Drosophila melanogaster

14 known processes

PebIII (Dmel_CG11390)

Ejaculatory bulb protein III

(Aliases: Dmel\CG11390,BcDNA:RH74005,PEBmeIII,CG11390,phk-2,Phk-2,PEB)

PebIII biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to biotic stimulus GO:0009607 294 0.333
response to external biotic stimulus GO:0043207 293 0.234
small molecule metabolic process GO:0044281 305 0.191
sensory perception of smell GO:0007608 80 0.138
chemical homeostasis GO:0048878 92 0.124
reproductive behavior GO:0019098 122 0.119
immune response GO:0006955 246 0.116
organonitrogen compound biosynthetic process GO:1901566 117 0.114
defense response to other organism GO:0098542 225 0.100
mesoderm development GO:0007498 78 0.099
death GO:0016265 284 0.088
lipid metabolic process GO:0006629 121 0.088
single organism biosynthetic process GO:0044711 206 0.074
oxoacid metabolic process GO:0043436 103 0.071
mating behavior GO:0007617 106 0.068
multi organism behavior GO:0051705 175 0.067
defense response to bacterium GO:0042742 178 0.063
gland morphogenesis GO:0022612 145 0.062
defense response GO:0006952 300 0.061
adult behavior GO:0030534 137 0.059
mating GO:0007618 120 0.059
cellular ketone metabolic process GO:0042180 24 0.058
courtship behavior GO:0007619 68 0.057
response to other organism GO:0051707 293 0.057
organonitrogen compound metabolic process GO:1901564 318 0.054
sensory perception GO:0007600 196 0.054
carboxylic acid metabolic process GO:0019752 92 0.053
response to organic substance GO:0010033 284 0.053
cell death GO:0008219 279 0.051
gland development GO:0048732 191 0.049
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.047
catabolic process GO:0009056 409 0.047
hormone biosynthetic process GO:0042446 20 0.047
response to bacterium GO:0009617 198 0.046
Fly
immune system process GO:0002376 347 0.046
response to oxygen containing compound GO:1901700 200 0.046
developmental programmed cell death GO:0010623 138 0.046
organic acid metabolic process GO:0006082 103 0.044
salivary gland development GO:0007431 162 0.043
intracellular signal transduction GO:0035556 300 0.041
neurological system process GO:0050877 358 0.037
salivary gland cell autophagic cell death GO:0035071 83 0.037
innate immune response GO:0045087 144 0.036
regionalization GO:0003002 416 0.036
exocrine system development GO:0035272 162 0.035
regulation of localization GO:0032879 275 0.034
positive regulation of protein metabolic process GO:0051247 128 0.034
cellular catabolic process GO:0044248 372 0.034
regulation of immune system process GO:0002682 176 0.033
multi organism reproductive behavior GO:0044705 121 0.033
programmed cell death GO:0012501 257 0.032
protein modification process GO:0036211 438 0.032
cellular response to chemical stimulus GO:0070887 199 0.031
mitotic spindle organization GO:0007052 220 0.030
multi multicellular organism process GO:0044706 123 0.030
tissue death GO:0016271 102 0.030
regulation of immune response GO:0050776 118 0.029
autophagic cell death GO:0048102 83 0.029
humoral immune response GO:0006959 117 0.029
regulation of cellular protein metabolic process GO:0032268 243 0.028
ovarian follicle cell development GO:0030707 248 0.028
cell division GO:0051301 248 0.027
carbohydrate derivative metabolic process GO:1901135 217 0.027
monocarboxylic acid metabolic process GO:0032787 29 0.027
regulation of intracellular transport GO:0032386 64 0.027
water homeostasis GO:0030104 3 0.026
vesicle mediated transport GO:0016192 381 0.026
actin cytoskeleton organization GO:0030036 206 0.026
single organism catabolic process GO:0044712 228 0.025
histolysis GO:0007559 102 0.025
feeding behavior GO:0007631 50 0.025
single organism intracellular transport GO:1902582 207 0.025
hormone metabolic process GO:0042445 33 0.025
cellular hormone metabolic process GO:0034754 23 0.025
regulation of hormone levels GO:0010817 40 0.025
homeostatic process GO:0042592 199 0.024
organic substance transport GO:0071702 257 0.024
positive regulation of cell communication GO:0010647 250 0.023
chitin based cuticle development GO:0040003 49 0.023
digestive system development GO:0055123 149 0.023
response to lipopolysaccharide GO:0032496 4 0.023
organic substance catabolic process GO:1901575 308 0.022
positive regulation of molecular function GO:0044093 136 0.022
negative regulation of cellular component organization GO:0051129 108 0.022
regulation of phosphorus metabolic process GO:0051174 210 0.021
sterol homeostasis GO:0055092 4 0.021
response to starvation GO:0042594 97 0.021
segmentation GO:0035282 207 0.021
salivary gland histolysis GO:0035070 88 0.021
cellular protein modification process GO:0006464 438 0.021
androgen metabolic process GO:0008209 1 0.020
regulation of cell cycle GO:0051726 291 0.020
regulation of cell differentiation GO:0045595 302 0.020
very long chain fatty acid metabolic process GO:0000038 4 0.020
regulation of cellular catabolic process GO:0031329 157 0.020
organic hydroxy compound metabolic process GO:1901615 83 0.020
microtubule organizing center organization GO:0031023 168 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.020
positive regulation of signaling GO:0023056 243 0.020
salivary gland morphogenesis GO:0007435 145 0.019
pigmentation GO:0043473 75 0.019
cellular amino acid metabolic process GO:0006520 61 0.019
negative regulation of cell differentiation GO:0045596 143 0.019
taxis GO:0042330 304 0.019
negative regulation of extracellular matrix organization GO:1903054 1 0.019
multicellular organismal reproductive behavior GO:0033057 110 0.018
spindle organization GO:0007051 253 0.018
cell recognition GO:0008037 102 0.018
neuron recognition GO:0008038 101 0.018
cellular chemical homeostasis GO:0055082 40 0.018
positive regulation of signal transduction GO:0009967 223 0.018
actin filament organization GO:0007015 126 0.018
tube development GO:0035295 244 0.018
cellular response to molecule of bacterial origin GO:0071219 3 0.018
convergent extension GO:0060026 2 0.017
biological adhesion GO:0022610 138 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.017
positive regulation of phosphorus metabolic process GO:0010562 139 0.017
oocyte construction GO:0007308 112 0.017
anterior posterior axis specification embryo GO:0008595 103 0.017
actin filament based process GO:0030029 220 0.017
cytoplasmic transport GO:0016482 130 0.017
single organism nuclear import GO:1902593 51 0.016
ras protein signal transduction GO:0007265 88 0.016
cell migration GO:0016477 238 0.016
regulation of catalytic activity GO:0050790 185 0.016
developmental pigmentation GO:0048066 68 0.016
lipid biosynthetic process GO:0008610 46 0.016
posttranscriptional regulation of gene expression GO:0010608 145 0.016
response to nutrient levels GO:0031667 114 0.016
cell proliferation GO:0008283 299 0.016
chromosome organization GO:0051276 360 0.016
steroid metabolic process GO:0008202 20 0.016
body morphogenesis GO:0010171 2 0.016
long chain fatty acid biosynthetic process GO:0042759 1 0.016
spindle elongation GO:0051231 83 0.016
negative regulation of signal transduction GO:0009968 206 0.016
cellular response to biotic stimulus GO:0071216 4 0.016
positive regulation of cellular protein metabolic process GO:0032270 118 0.016
regulation of cell death GO:0010941 173 0.016
regulation of molecular function GO:0065009 217 0.015
regulation of cellular localization GO:0060341 136 0.015
regulation of innate immune response GO:0045088 71 0.015
ovarian follicle cell migration GO:0007297 121 0.015
single organism cellular localization GO:1902580 180 0.015
regulation of protein metabolic process GO:0051246 256 0.015
positive regulation of response to stimulus GO:0048584 323 0.015
wnt signaling pathway GO:0016055 98 0.015
defense response to fungus GO:0050832 48 0.015
protein localization GO:0008104 284 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
protein complex biogenesis GO:0070271 201 0.014
epithelial cell development GO:0002064 274 0.014
regulation of mitotic cell cycle GO:0007346 190 0.014
ion transport GO:0006811 145 0.014
protein localization to organelle GO:0033365 82 0.014
cellular homeostasis GO:0019725 80 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
positive regulation of cell motility GO:2000147 3 0.014
synaptic target recognition GO:0008039 45 0.014
positive regulation of phosphate metabolic process GO:0045937 139 0.014
aromatic compound catabolic process GO:0019439 166 0.014
anterior posterior pattern specification GO:0009952 136 0.014
response to abiotic stimulus GO:0009628 341 0.014
regulation of catabolic process GO:0009894 170 0.014
positive regulation of cellular catabolic process GO:0031331 95 0.014
phagocytosis GO:0006909 215 0.013
anatomical structure homeostasis GO:0060249 97 0.013
oocyte differentiation GO:0009994 145 0.013
extracellular structure organization GO:0043062 46 0.013
hormone catabolic process GO:0042447 3 0.013
establishment of localization in cell GO:0051649 402 0.013
pheromone biosynthetic process GO:0042811 3 0.013
cell motility GO:0048870 251 0.013
tube morphogenesis GO:0035239 191 0.013
columnar cuboidal epithelial cell development GO:0002066 249 0.013
regulation of cytoskeleton organization GO:0051493 89 0.013
pigment metabolic process involved in pigmentation GO:0043474 33 0.013
cellular amine metabolic process GO:0044106 12 0.013
regulation of response to external stimulus GO:0032101 115 0.013
cuticle development GO:0042335 86 0.013
cytokinesis GO:0000910 90 0.013
negative regulation of cell death GO:0060548 81 0.012
intracellular ph reduction GO:0051452 7 0.012
maintenance of location GO:0051235 73 0.012
rna localization GO:0006403 115 0.012
mitotic spindle elongation GO:0000022 81 0.012
protein localization to nucleus GO:0034504 55 0.012
vitamin metabolic process GO:0006766 2 0.012
open tracheal system development GO:0007424 204 0.012
mitotic cell cycle phase transition GO:0044772 138 0.012
camera type eye development GO:0043010 4 0.012
wound healing GO:0042060 75 0.012
regulation of protein localization GO:0032880 76 0.012
intracellular transport GO:0046907 228 0.012
response to alcohol GO:0097305 95 0.012
positive regulation of catabolic process GO:0009896 105 0.012
ameboidal type cell migration GO:0001667 151 0.012
protein import GO:0017038 55 0.012
small molecule biosynthetic process GO:0044283 37 0.012
very long chain fatty acid biosynthetic process GO:0042761 2 0.012
regulation of establishment of protein localization GO:0070201 61 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
regulation of multi organism process GO:0043900 131 0.012
eggshell formation GO:0030703 105 0.012
negative regulation of gene expression GO:0010629 387 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.011
secondary metabolite biosynthetic process GO:0044550 24 0.011
gene silencing GO:0016458 138 0.011
cellular response to organic substance GO:0071310 132 0.011
mitotic cytokinesis GO:0000281 50 0.011
regulation of response to stress GO:0080134 200 0.011
imaginal disc derived wing morphogenesis GO:0007476 337 0.011
oxidation reduction process GO:0055114 123 0.011
post embryonic appendage morphogenesis GO:0035120 385 0.011
wing disc morphogenesis GO:0007472 344 0.011
fatty acid elongation GO:0030497 3 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
regulation of protein modification process GO:0031399 112 0.011
positive regulation of macromolecule metabolic process GO:0010604 405 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
regulation of actin filament polymerization GO:0030833 25 0.011
negative regulation of cell communication GO:0010648 223 0.011
establishment of protein localization GO:0045184 163 0.011
negative regulation of response to stimulus GO:0048585 258 0.011
protein complex assembly GO:0006461 200 0.011
single organism behavior GO:0044708 391 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
developmental maturation GO:0021700 172 0.010
regulation of transport GO:0051049 181 0.010
cell cell signaling involved in cell fate commitment GO:0045168 210 0.010
regulation of response to biotic stimulus GO:0002831 63 0.010
negative regulation of extracellular matrix disassembly GO:0010716 1 0.010
anterior posterior axis specification GO:0009948 109 0.010
regulation of cytoplasmic transport GO:1903649 47 0.010
endomembrane system organization GO:0010256 119 0.010
stem cell differentiation GO:0048863 117 0.010
centrosome organization GO:0051297 163 0.010
regulation of phosphate metabolic process GO:0019220 210 0.010
macromolecular complex assembly GO:0065003 256 0.010
nucleoside triphosphate metabolic process GO:0009141 120 0.010
antimicrobial humoral response GO:0019730 99 0.010
cellular response to lipopolysaccharide GO:0071222 3 0.010
response to extracellular stimulus GO:0009991 116 0.010

PebIII disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.077
eye and adnexa disease DOID:1492 0 0.053
sensory system disease DOID:0050155 0 0.053
nervous system disease DOID:863 0 0.053
musculoskeletal system disease DOID:17 0 0.014
eye disease DOID:5614 0 0.012
retinal disease DOID:5679 0 0.012