Drosophila melanogaster

56 known processes

Mcm7 (Dmel_CG4978)

Minichromosome maintenance 7

(Aliases: McM7,anon-EST:Liang-1.66,CG4978,clone 1.66,Dmel\CG4978,MCM7,DmMCM7,PCR1,DmeMCM7,mcm7,Mcp-PCR1)

Mcm7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein dna complex assembly GO:0065004 63 0.784
Yeast
meiosis i GO:0007127 59 0.629
dna metabolic process GO:0006259 227 0.615
cellular response to dna damage stimulus GO:0006974 223 0.567
dna repair GO:0006281 54 0.539
Yeast
dna geometric change GO:0032392 16 0.467
negative regulation of cell cycle GO:0045786 116 0.466
cell cycle dna replication GO:0044786 23 0.453
Yeast
dna recombination GO:0006310 32 0.416
Yeast
negative regulation of cellular biosynthetic process GO:0031327 277 0.410
Yeast
nuclear dna replication GO:0033260 1 0.385
Yeast
dna conformation change GO:0071103 105 0.376
regulation of cell cycle GO:0051726 291 0.361
dna replication GO:0006260 48 0.311
Yeast Mouse
mitotic cell cycle checkpoint GO:0007093 88 0.311
negative regulation of cellular metabolic process GO:0031324 382 0.297
Yeast
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.294
Yeast
double strand break repair via nonhomologous end joining GO:0006303 5 0.286
g2 dna damage checkpoint GO:0031572 69 0.281
negative regulation of mitotic cell cycle GO:0045930 109 0.278
double strand break repair GO:0006302 26 0.249
Yeast
chromosome separation GO:0051304 42 0.245
regulation of cell cycle process GO:0010564 181 0.235
mitotic g2 m transition checkpoint GO:0044818 70 0.235
negative regulation of cell cycle process GO:0010948 109 0.227
meiotic nuclear division GO:0007126 151 0.222
macromolecular complex assembly GO:0065003 256 0.219
Yeast
negative regulation of cell cycle phase transition GO:1901988 103 0.215
mitotic dna damage checkpoint GO:0044773 74 0.212
cell migration GO:0016477 238 0.208
cell cycle checkpoint GO:0000075 95 0.208
endocytosis GO:0006897 310 0.203
dna integrity checkpoint GO:0031570 81 0.193
negative regulation of rna biosynthetic process GO:1902679 240 0.191
Yeast
mitotic cell cycle phase transition GO:0044772 138 0.186
negative regulation of gene expression epigenetic GO:0045814 77 0.185
Yeast
double strand break repair via homologous recombination GO:0000724 13 0.183
Yeast
protein dna complex subunit organization GO:0071824 86 0.181
Yeast
embryo development ending in birth or egg hatching GO:0009792 152 0.180
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.179
Yeast
dna packaging GO:0006323 91 0.178
meiotic cell cycle GO:0051321 171 0.177
nucleotide excision repair GO:0006289 8 0.172
nuclear division GO:0000280 332 0.168
regulation of mitotic cell cycle GO:0007346 190 0.162
negative regulation of gene expression GO:0010629 387 0.155
Yeast
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.155
Yeast
recombinational repair GO:0000725 13 0.153
Yeast
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.151
regulation of cell death GO:0010941 173 0.151
cell motility GO:0048870 251 0.149
small molecule metabolic process GO:0044281 305 0.149
Human Yeast
dna damage checkpoint GO:0000077 78 0.147
organelle fission GO:0048285 340 0.144
death GO:0016265 284 0.140
cell division GO:0051301 248 0.131
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.126
Yeast
meiotic cell cycle process GO:1903046 132 0.123
localization of cell GO:0051674 257 0.118
negative regulation of transcription dna templated GO:0045892 237 0.112
Yeast
mitotic dna integrity checkpoint GO:0044774 75 0.112
cell cycle phase transition GO:0044770 140 0.108
mitotic g2 dna damage checkpoint GO:0007095 69 0.101
body morphogenesis GO:0010171 2 0.100
chromatin silencing GO:0006342 76 0.099
Yeast
mitotic nuclear division GO:0007067 213 0.098
cell proliferation GO:0008283 299 0.097
Mouse
cell death GO:0008219 279 0.095
nucleosome assembly GO:0006334 35 0.093
meiotic chromosome segregation GO:0045132 59 0.091
negative regulation of biosynthetic process GO:0009890 277 0.086
Yeast
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.085
regulation of mitotic sister chromatid segregation GO:0033047 28 0.084
negative regulation of nucleic acid templated transcription GO:1903507 240 0.082
Yeast
chromosome organization GO:0051276 360 0.082
chromosome segregation GO:0007059 157 0.081
reproductive system development GO:0061458 74 0.079
negative regulation of cellular component organization GO:0051129 108 0.079
negative regulation of organelle organization GO:0010639 56 0.078
single organism biosynthetic process GO:0044711 206 0.078
Yeast
immune response GO:0006955 246 0.075
development of primary sexual characteristics GO:0045137 50 0.074
carboxylic acid metabolic process GO:0019752 92 0.073
zymogen activation GO:0031638 20 0.071
response to endogenous stimulus GO:0009719 119 0.070
response to organic substance GO:0010033 284 0.068
regulation of chromosome organization GO:0033044 64 0.066
negative regulation of response to stimulus GO:0048585 258 0.066
dna duplex unwinding GO:0032508 16 0.065
larval development GO:0002164 104 0.064
protein localization GO:0008104 284 0.064
regulation of apoptotic process GO:0042981 130 0.063
regulation of cell division GO:0051302 72 0.062
regulation of programmed cell death GO:0043067 152 0.060
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.059
proteolysis GO:0006508 192 0.059
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.058
mitotic spindle checkpoint GO:0071174 11 0.055
regulation of cellular response to stress GO:0080135 89 0.053
regulation of cell differentiation GO:0045595 302 0.052
activation of cysteine type endopeptidase activity GO:0097202 17 0.052
chromatin remodeling GO:0006338 72 0.051
regulation of cell cycle phase transition GO:1901987 130 0.050
single organism intracellular transport GO:1902582 207 0.050
enzyme linked receptor protein signaling pathway GO:0007167 179 0.050
embryonic morphogenesis GO:0048598 206 0.050
regulation of mitotic cell cycle phase transition GO:1901990 130 0.049
gonad development GO:0008406 50 0.049
mitotic sister chromatid separation GO:0051306 30 0.049
negative regulation of rna metabolic process GO:0051253 251 0.048
Yeast
establishment of localization in cell GO:0051649 402 0.046
organonitrogen compound metabolic process GO:1901564 318 0.045
Human Yeast
chromatin modification GO:0016568 147 0.044
vesicle mediated transport GO:0016192 381 0.044
response to abiotic stimulus GO:0009628 341 0.043
mitotic spindle organization GO:0007052 220 0.043
protein maturation GO:0051604 71 0.042
histone modification GO:0016570 106 0.042
regulation of phosphate metabolic process GO:0019220 210 0.041
Human
dna biosynthetic process GO:0071897 24 0.041
organic acid metabolic process GO:0006082 103 0.041
positive regulation of endopeptidase activity GO:0010950 26 0.040
catabolic process GO:0009056 409 0.039
Human Yeast
single organism behavior GO:0044708 391 0.039
imaginal disc derived appendage development GO:0048737 399 0.039
protein modification process GO:0036211 438 0.038
positive regulation of molecular function GO:0044093 136 0.038
chromatin organization GO:0006325 207 0.037
cellular response to chemical stimulus GO:0070887 199 0.035
regulation of response to stress GO:0080134 200 0.035
negative regulation of chromosome organization GO:2001251 19 0.035
central nervous system development GO:0007417 201 0.035
regulation of proteolysis GO:0030162 87 0.035
response to radiation GO:0009314 155 0.035
cellular macromolecular complex assembly GO:0034622 153 0.035
Yeast
appendage development GO:0048736 401 0.034
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.034
aging GO:0007568 143 0.034
apoptotic process GO:0006915 159 0.034
regulation of dna recombination GO:0000018 4 0.034
regulation of multicellular organismal development GO:2000026 414 0.033
tube development GO:0035295 244 0.032
intracellular transport GO:0046907 228 0.032
negative regulation of sister chromatid segregation GO:0033046 13 0.032
protein complex assembly GO:0006461 200 0.032
regulation of mitosis GO:0007088 56 0.032
reciprocal dna recombination GO:0035825 19 0.032
spindle organization GO:0007051 253 0.031
reciprocal meiotic recombination GO:0007131 19 0.031
negative regulation of developmental process GO:0051093 201 0.031
regulation of cell proliferation GO:0042127 163 0.030
regulation of cellular protein metabolic process GO:0032268 243 0.030
phosphorylation GO:0016310 294 0.030
Human
positive regulation of transcription dna templated GO:0045893 266 0.030
cellular macromolecule localization GO:0070727 220 0.029
non recombinational repair GO:0000726 7 0.029
single organism cellular localization GO:1902580 180 0.029
humoral immune response GO:0006959 117 0.029
organic substance transport GO:0071702 257 0.029
reproductive structure development GO:0048608 74 0.029
regulation of cellular component biogenesis GO:0044087 201 0.029
organophosphate metabolic process GO:0019637 195 0.029
Human Yeast
resolution of meiotic recombination intermediates GO:0000712 6 0.029
response to external biotic stimulus GO:0043207 293 0.028
programmed cell death GO:0012501 257 0.028
ribonucleotide metabolic process GO:0009259 145 0.027
Human Yeast
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.027
regulation of meiosis GO:0040020 3 0.027
response to biotic stimulus GO:0009607 294 0.027
regulation of sister chromatid segregation GO:0033045 28 0.027
cellular nitrogen compound catabolic process GO:0044270 165 0.027
Human Yeast
aromatic compound catabolic process GO:0019439 166 0.026
Human Yeast
single organism catabolic process GO:0044712 228 0.026
Human Yeast
regulation of cysteine type endopeptidase activity GO:2000116 27 0.026
negative regulation of cell division GO:0051782 17 0.026
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.026
postreplication repair GO:0006301 2 0.025
negative regulation of meiotic cell cycle GO:0051447 2 0.025
regulation of mitotic sister chromatid separation GO:0010965 28 0.025
nucleoside phosphate metabolic process GO:0006753 162 0.025
Human Yeast
regulation of organelle organization GO:0033043 196 0.024
immune system process GO:0002376 347 0.024
protein transport GO:0015031 155 0.024
negative regulation of catabolic process GO:0009895 36 0.023
dna dependent dna replication GO:0006261 17 0.023
Yeast Mouse
heterocycle catabolic process GO:0046700 166 0.023
Human Yeast
regulation of nuclear division GO:0051783 58 0.023
covalent chromatin modification GO:0016569 106 0.023
camera type eye development GO:0043010 4 0.023
cellular macromolecule catabolic process GO:0044265 136 0.023
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.023
positive regulation of cellular component biogenesis GO:0044089 80 0.023
organic cyclic compound catabolic process GO:1901361 168 0.022
Human Yeast
positive regulation of hydrolase activity GO:0051345 78 0.022
appendage morphogenesis GO:0035107 397 0.022
metaphase anaphase transition of cell cycle GO:0044784 28 0.022
protein targeting to nucleus GO:0044744 51 0.022
regulation of phosphorus metabolic process GO:0051174 210 0.022
Human
intracellular protein transport GO:0006886 104 0.022
organic substance catabolic process GO:1901575 308 0.022
Human Yeast
amine metabolic process GO:0009308 12 0.022
positive regulation of cellular component organization GO:0051130 156 0.021
dna double strand break processing GO:0000729 3 0.021
negative regulation of cell death GO:0060548 81 0.021
purine nucleoside triphosphate catabolic process GO:0009146 108 0.021
Human Yeast
intermediate filament cytoskeleton organization GO:0045104 1 0.021
regulation of hydrolase activity GO:0051336 97 0.021
positive regulation of phosphate metabolic process GO:0045937 139 0.021
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.020
positive regulation of catalytic activity GO:0043085 118 0.020
negative regulation of chromosome segregation GO:0051985 14 0.020
dna replication initiation GO:0006270 6 0.020
Yeast
nucleotide metabolic process GO:0009117 161 0.020
Human Yeast
regulation of catalytic activity GO:0050790 185 0.019
positive regulation of macromolecule metabolic process GO:0010604 405 0.019
multi organism behavior GO:0051705 175 0.019
cellular amino acid metabolic process GO:0006520 61 0.019
regulation of molecular function GO:0065009 217 0.019
regulation of gene expression epigenetic GO:0040029 128 0.019
Yeast
nucleoside triphosphate metabolic process GO:0009141 120 0.018
Human Yeast
cellular protein modification process GO:0006464 438 0.018
histone methylation GO:0016571 40 0.018
regulation of chromatin silencing GO:0031935 36 0.018
regulation of localization GO:0032879 275 0.018
multicellular organismal aging GO:0010259 140 0.018
positive regulation of proteolysis GO:0045862 52 0.018
small gtpase mediated signal transduction GO:0007264 88 0.017
regulation of catabolic process GO:0009894 170 0.017
positive regulation of programmed cell death GO:0043068 62 0.017
regulation of phosphorylation GO:0042325 147 0.017
Human
epithelial cell differentiation GO:0030855 322 0.016
actin filament based process GO:0030029 220 0.016
regulation of anatomical structure morphogenesis GO:0022603 242 0.016
regulation of protein metabolic process GO:0051246 256 0.016
female meiosis chromosome segregation GO:0016321 33 0.016
nucleobase containing compound catabolic process GO:0034655 165 0.016
Human Yeast
cellular response to organic substance GO:0071310 132 0.016
negative regulation of dna metabolic process GO:0051053 12 0.015
regulation of dna metabolic process GO:0051052 34 0.015
spindle assembly involved in mitosis GO:0090307 50 0.015
dna amplification GO:0006277 11 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
regulation of peptidase activity GO:0052547 39 0.015
regulation of immune system process GO:0002682 176 0.015
oxidation reduction process GO:0055114 123 0.015
protein processing GO:0016485 68 0.015
stem cell proliferation GO:0072089 88 0.015
response to light stimulus GO:0009416 124 0.015
ribose phosphate metabolic process GO:0019693 145 0.015
Human Yeast
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.015
regulation of histone modification GO:0031056 20 0.015
intracellular signal transduction GO:0035556 300 0.015
protein complex biogenesis GO:0070271 201 0.014
cellular catabolic process GO:0044248 372 0.014
Human Yeast
cell cycle g1 s phase transition GO:0044843 31 0.014
ribonucleoside catabolic process GO:0042454 112 0.014
Human Yeast
regulation of endopeptidase activity GO:0052548 36 0.014
cellular amine metabolic process GO:0044106 12 0.014
ribonucleoside metabolic process GO:0009119 127 0.014
Human Yeast
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
Human Yeast
muscle organ development GO:0007517 127 0.014
peptidyl amino acid modification GO:0018193 105 0.014
cellular response to endogenous stimulus GO:0071495 80 0.014
protein localization to nucleus GO:0034504 55 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
negative regulation of apoptotic process GO:0043066 63 0.013
positive regulation of response to stimulus GO:0048584 323 0.013
methylation GO:0032259 47 0.013
response to nitrogen compound GO:1901698 90 0.013
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.013
growth GO:0040007 359 0.013
regulation of cell development GO:0060284 215 0.013
regulation of cytoskeleton organization GO:0051493 89 0.013
cellular response to oxygen containing compound GO:1901701 79 0.013
establishment of protein localization GO:0045184 163 0.013
establishment or maintenance of cell polarity GO:0007163 167 0.013
ras protein signal transduction GO:0007265 88 0.013
regulation of response to dna damage stimulus GO:2001020 23 0.013
developmental growth GO:0048589 280 0.013
protein alkylation GO:0008213 43 0.012
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
macromolecule catabolic process GO:0009057 161 0.012
positive regulation of gene expression GO:0010628 290 0.012
regulation of proteasomal protein catabolic process GO:0061136 39 0.012
positive regulation of protein metabolic process GO:0051247 128 0.012
protein phosphorylation GO:0006468 169 0.012
epithelial tube morphogenesis GO:0060562 88 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
Human Yeast
positive regulation of binding GO:0051099 4 0.012
negative regulation of cellular catabolic process GO:0031330 34 0.012
ribonucleoside triphosphate catabolic process GO:0009203 108 0.012
Human Yeast
regulation of cellular localization GO:0060341 136 0.012
imaginal disc derived appendage morphogenesis GO:0035114 395 0.012
atp catabolic process GO:0006200 38 0.012
Human Yeast
purine containing compound metabolic process GO:0072521 155 0.012
Human Yeast
regulation of developmental growth GO:0048638 174 0.012
regulation of cell morphogenesis GO:0022604 163 0.012
response to other organism GO:0051707 293 0.012
positive regulation of cell differentiation GO:0045597 64 0.011
negative regulation of programmed cell death GO:0043069 72 0.011
dna catabolic process GO:0006308 16 0.011
response to inorganic substance GO:0010035 44 0.011
nuclear transport GO:0051169 72 0.011
progression of morphogenetic furrow involved in compound eye morphogenesis GO:0007458 8 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.011
Human Yeast
tube morphogenesis GO:0035239 191 0.011
organophosphate catabolic process GO:0046434 112 0.011
Human Yeast
purine ribonucleoside catabolic process GO:0046130 112 0.011
Human Yeast
regulation of meiotic cell cycle GO:0051445 9 0.011
limb development GO:0060173 1 0.011
camera type eye morphogenesis GO:0048593 2 0.011
determination of adult lifespan GO:0008340 137 0.011
organelle assembly GO:0070925 198 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
Human Yeast
heart development GO:0007507 82 0.010
phagocytosis GO:0006909 215 0.010
single organism nuclear import GO:1902593 51 0.010
multi multicellular organism process GO:0044706 123 0.010
regulation of double strand break repair GO:2000779 3 0.010
post embryonic appendage morphogenesis GO:0035120 385 0.010
protein methylation GO:0006479 43 0.010
negative regulation of cellular protein metabolic process GO:0032269 85 0.010
positive regulation of mitotic cell cycle GO:0045931 34 0.010
sex differentiation GO:0007548 81 0.010
mitotic spindle assembly checkpoint GO:0007094 11 0.010
g1 s transition of mitotic cell cycle GO:0000082 31 0.010
homeostatic process GO:0042592 199 0.010

Mcm7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.029
disease of cellular proliferation DOID:14566 0 0.029
organ system cancer DOID:0050686 0 0.024
disease of anatomical entity DOID:7 0 0.021