Drosophila melanogaster

31 known processes

Mes-4 (Dmel_CG4976)

CG4976 gene product from transcript CG4976-RA

(Aliases: dMES-4,Dmel\CG4976,CG4976,dMes-4)

Mes-4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 227 0.813
Mouse
chromosome organization GO:0051276 360 0.612
nuclear division GO:0000280 332 0.272
negative regulation of cellular biosynthetic process GO:0031327 277 0.259
Mouse
protein dna complex subunit organization GO:0071824 86 0.158
meiotic nuclear division GO:0007126 151 0.123
cellular catabolic process GO:0044248 372 0.121
catabolic process GO:0009056 409 0.116
dna conformation change GO:0071103 105 0.100
modification dependent macromolecule catabolic process GO:0043632 79 0.085
regulation of organelle organization GO:0033043 196 0.078
positive regulation of rna biosynthetic process GO:1902680 266 0.075
Human
cellular response to dna damage stimulus GO:0006974 223 0.067
Mouse
chromatin modification GO:0016568 147 0.065
negative regulation of rna biosynthetic process GO:1902679 240 0.065
Mouse
organelle fission GO:0048285 340 0.064
meiotic cell cycle GO:0051321 171 0.063
ubiquitin dependent protein catabolic process GO:0006511 78 0.058
embryo development ending in birth or egg hatching GO:0009792 152 0.057
Zebrafish
cellular macromolecule catabolic process GO:0044265 136 0.055
regulation of multicellular organismal development GO:2000026 414 0.053
Mouse
chromosome segregation GO:0007059 157 0.051
cell proliferation GO:0008283 299 0.051
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.050
Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.048
Mouse
regulation of cell cycle GO:0051726 291 0.047
dna replication GO:0006260 48 0.047
modification dependent protein catabolic process GO:0019941 78 0.043
cellular macromolecular complex assembly GO:0034622 153 0.042
organic substance catabolic process GO:1901575 308 0.041
cell death GO:0008219 279 0.041
protein localization GO:0008104 284 0.041
Mouse
macromolecular complex assembly GO:0065003 256 0.040
protein catabolic process GO:0030163 101 0.040
regulation of chromosome organization GO:0033044 64 0.039
proteolysis GO:0006508 192 0.039
body morphogenesis GO:0010171 2 0.038
regulation of programmed cell death GO:0043067 152 0.037
mitotic nuclear division GO:0007067 213 0.035
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.035
Human Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.035
Human
cellular protein catabolic process GO:0044257 83 0.034
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.034
dna repair GO:0006281 54 0.034
Mouse
mitotic sister chromatid segregation GO:0000070 87 0.034
positive regulation of response to stimulus GO:0048584 323 0.034
Mouse
death GO:0016265 284 0.033
response to abiotic stimulus GO:0009628 341 0.032
macromolecule catabolic process GO:0009057 161 0.032
histone modification GO:0016570 106 0.032
covalent chromatin modification GO:0016569 106 0.031
chromosome separation GO:0051304 42 0.030
protein complex assembly GO:0006461 200 0.030
negative regulation of cellular metabolic process GO:0031324 382 0.029
Mouse
chromatin silencing GO:0006342 76 0.029
vesicle mediated transport GO:0016192 381 0.029
cell division GO:0051301 248 0.028
heterocycle catabolic process GO:0046700 166 0.028
aromatic compound catabolic process GO:0019439 166 0.028
sister chromatid segregation GO:0000819 92 0.027
organonitrogen compound metabolic process GO:1901564 318 0.026
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.026
mrna metabolic process GO:0016071 124 0.026
cellular protein modification process GO:0006464 438 0.026
regulation of proteasomal protein catabolic process GO:0061136 39 0.026
chromatin remodeling GO:0006338 72 0.026
nucleosome organization GO:0034728 59 0.025
programmed cell death GO:0012501 257 0.025
nucleobase containing compound catabolic process GO:0034655 165 0.025
mitotic sister chromatid separation GO:0051306 30 0.024
positive regulation of signaling GO:0023056 243 0.024
small molecule metabolic process GO:0044281 305 0.024
negative regulation of neurotransmitter secretion GO:0046929 2 0.024
protein targeting GO:0006605 64 0.023
positive regulation of macromolecule metabolic process GO:0010604 405 0.023
Human Mouse
proteasomal protein catabolic process GO:0010498 59 0.023
negative regulation of gene expression epigenetic GO:0045814 77 0.023
apoptotic process GO:0006915 159 0.022
positive regulation of cell communication GO:0010647 250 0.022
positive regulation of nucleic acid templated transcription GO:1903508 266 0.022
Human
positive regulation of transcription dna templated GO:0045893 266 0.021
Human
imaginal disc derived wing morphogenesis GO:0007476 337 0.021
establishment of localization in cell GO:0051649 402 0.021
meiotic cell cycle process GO:1903046 132 0.020
protein transport GO:0015031 155 0.020
muscle structure development GO:0061061 224 0.020
positive regulation of biosynthetic process GO:0009891 316 0.020
Human
positive regulation of signal transduction GO:0009967 223 0.020
positive regulation of rna metabolic process GO:0051254 271 0.019
Human
negative regulation of nucleic acid templated transcription GO:1903507 240 0.019
Mouse
organic cyclic compound catabolic process GO:1901361 168 0.019
chromatin organization GO:0006325 207 0.019
organic acid metabolic process GO:0006082 103 0.019
positive regulation of cellular biosynthetic process GO:0031328 316 0.018
Human
cellular protein localization GO:0034613 160 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.018
Mouse
mitotic spindle organization GO:0007052 220 0.017
organelle assembly GO:0070925 198 0.017
regulation of cell death GO:0010941 173 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
single organism catabolic process GO:0044712 228 0.017
spindle organization GO:0007051 253 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.017
Human Mouse
regionalization GO:0003002 416 0.016
endocytosis GO:0006897 310 0.016
wing disc morphogenesis GO:0007472 344 0.015
transcription from rna polymerase ii promoter GO:0006366 368 0.015
Mouse
oxoacid metabolic process GO:0043436 103 0.015
positive regulation of multicellular organismal process GO:0051240 143 0.015
Mouse
phosphorylation GO:0016310 294 0.015
imaginal disc derived appendage morphogenesis GO:0035114 395 0.015
intracellular signal transduction GO:0035556 300 0.015
anterior posterior pattern specification GO:0009952 136 0.015
regulation of cell cycle process GO:0010564 181 0.015
positive regulation of gene expression GO:0010628 290 0.014
Human
regulation of cell proliferation GO:0042127 163 0.014
negative regulation of gene expression GO:0010629 387 0.014
Mouse
multi multicellular organism process GO:0044706 123 0.014
regulation of chromatin organization GO:1902275 32 0.013
double strand break repair GO:0006302 26 0.013
Mouse
intracellular transport GO:0046907 228 0.013
regulation of cell division GO:0051302 72 0.013
multi organism behavior GO:0051705 175 0.013
single organism intracellular transport GO:1902582 207 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
chromatin assembly or disassembly GO:0006333 52 0.013
establishment of protein localization GO:0045184 163 0.013
Mouse
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.013
larval development GO:0002164 104 0.013
phagocytosis GO:0006909 215 0.012
response to biotic stimulus GO:0009607 294 0.012
protein complex biogenesis GO:0070271 201 0.012
heterochromatin organization GO:0070828 25 0.012
cellular macromolecule localization GO:0070727 220 0.012
regulation of mitotic cell cycle phase transition GO:1901990 130 0.012
protein modification process GO:0036211 438 0.012
negative regulation of biosynthetic process GO:0009890 277 0.012
Mouse
reproductive structure development GO:0048608 74 0.012
appendage development GO:0048736 401 0.012
regulation of apoptotic process GO:0042981 130 0.012
atp dependent chromatin remodeling GO:0043044 22 0.012
homeostatic process GO:0042592 199 0.012
regulation of protein catabolic process GO:0042176 55 0.011
meiosis i GO:0007127 59 0.011
developmental growth GO:0048589 280 0.011
single organism cellular localization GO:1902580 180 0.011
cellular protein complex assembly GO:0043623 71 0.011
sensory organ morphogenesis GO:0090596 260 0.011
imaginal disc derived appendage development GO:0048737 399 0.011
regulation of catalytic activity GO:0050790 185 0.011
regulation of molecular function GO:0065009 217 0.011
regulation of phosphatase activity GO:0010921 3 0.011
dna duplex unwinding GO:0032508 16 0.011
dna packaging GO:0006323 91 0.010
positive regulation of intracellular signal transduction GO:1902533 116 0.010
embryonic morphogenesis GO:0048598 206 0.010
Mouse
mrna processing GO:0006397 104 0.010
nucleoside phosphate catabolic process GO:1901292 110 0.010
purine ribonucleotide metabolic process GO:0009150 145 0.010

Mes-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.012
organ system cancer DOID:0050686 0 0.010
Human
disease of cellular proliferation DOID:14566 0 0.010
Human
cancer DOID:162 0 0.010
Human
syndrome DOID:225 0 0.010
Human