Drosophila melanogaster

11 known processes

CLIP-190 (Dmel_CG5020)

Cytoplasmic linker protein 190

(Aliases: Dmel\CG5020,Clip-190,D-Clip-190,CG5020,D-CLIP-19,CLIP190,Clip190,Clip- 190,D-CLIP-195,D-CLIP-90,D-CLIP-190)

CLIP-190 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein removal GO:0070646 28 0.176
cellular protein modification process GO:0006464 438 0.131
Human
programmed cell death GO:0012501 257 0.118
Human
cellular macromolecule catabolic process GO:0044265 136 0.110
death GO:0016265 284 0.108
Human
regulation of reproductive process GO:2000241 54 0.105
organic substance catabolic process GO:1901575 308 0.097
regulation of cellular component biogenesis GO:0044087 201 0.089
Human
regulation of cell death GO:0010941 173 0.086
Human
regulation of multi organism process GO:0043900 131 0.086
negative regulation of response to stimulus GO:0048585 258 0.085
protein modification process GO:0036211 438 0.082
Human
catabolic process GO:0009056 409 0.078
regulation of localization GO:0032879 275 0.077
Human
regulation of cell development GO:0060284 215 0.068
cell division GO:0051301 248 0.065
cellular catabolic process GO:0044248 372 0.064
imaginal disc derived wing morphogenesis GO:0007476 337 0.062
homeostatic process GO:0042592 199 0.062
dna metabolic process GO:0006259 227 0.060
chaeta development GO:0022416 97 0.059
wing disc morphogenesis GO:0007472 344 0.057
developmental maturation GO:0021700 172 0.056
cellular macromolecule localization GO:0070727 220 0.056
Mouse
regulation of multicellular organismal development GO:2000026 414 0.055
protein modification by small protein conjugation or removal GO:0070647 106 0.054
regulation of response to stress GO:0080134 200 0.053
cellular nitrogen compound catabolic process GO:0044270 165 0.049
post embryonic appendage morphogenesis GO:0035120 385 0.047
ras protein signal transduction GO:0007265 88 0.047
chromosome segregation GO:0007059 157 0.047
establishment or maintenance of cell polarity GO:0007163 167 0.046
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.045
protein phosphorylation GO:0006468 169 0.045
negative regulation of cellular metabolic process GO:0031324 382 0.044
negative regulation of signal transduction GO:0009968 206 0.044
spindle organization GO:0007051 253 0.042
immune system process GO:0002376 347 0.042
meiotic cell cycle GO:0051321 171 0.041
protein localization GO:0008104 284 0.041
Human Mouse
endocytosis GO:0006897 310 0.041
Human
appendage morphogenesis GO:0035107 397 0.041
aromatic compound catabolic process GO:0019439 166 0.041
appendage development GO:0048736 401 0.041
negative regulation of signaling GO:0023057 219 0.040
oocyte development GO:0048599 124 0.040
modification dependent macromolecule catabolic process GO:0043632 79 0.039
regulation of cell differentiation GO:0045595 302 0.039
kidney development GO:0001822 3 0.039
regulation of apoptotic process GO:0042981 130 0.038
Human
regulation of mitotic cell cycle GO:0007346 190 0.036
axis specification GO:0009798 167 0.036
organic cyclic compound catabolic process GO:1901361 168 0.036
growth GO:0040007 359 0.036
neurological system process GO:0050877 358 0.036
positive regulation of cellular component organization GO:0051130 156 0.035
Human
imaginal disc derived appendage morphogenesis GO:0035114 395 0.035
regulation of cellular localization GO:0060341 136 0.035
positive regulation of nucleic acid templated transcription GO:1903508 266 0.034
oocyte axis specification GO:0007309 108 0.034
transcription from rna polymerase ii promoter GO:0006366 368 0.033
macromolecule catabolic process GO:0009057 161 0.032
intracellular signal transduction GO:0035556 300 0.032
single organism cellular localization GO:1902580 180 0.031
Mouse
negative regulation of cell communication GO:0010648 223 0.031
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.031
positive regulation of gene expression GO:0010628 290 0.031
positive regulation of biosynthetic process GO:0009891 316 0.030
axon development GO:0061564 297 0.030
regulation of intracellular signal transduction GO:1902531 236 0.030
sister chromatid segregation GO:0000819 92 0.029
regulation of cell cycle GO:0051726 291 0.029
regulation of transport GO:0051049 181 0.029
Human
segmentation GO:0035282 207 0.029
regulation of developmental growth GO:0048638 174 0.028
chemotaxis GO:0006935 249 0.028
molting cycle chitin based cuticle GO:0007591 56 0.028
imaginal disc derived appendage development GO:0048737 399 0.028
heterocycle catabolic process GO:0046700 166 0.028
cytoskeleton dependent cytokinesis GO:0061640 81 0.028
rna catabolic process GO:0006401 37 0.028
phosphorylation GO:0016310 294 0.027
apoptotic process GO:0006915 159 0.026
Human
chromosome organization GO:0051276 360 0.026
small gtpase mediated signal transduction GO:0007264 88 0.026
organonitrogen compound metabolic process GO:1901564 318 0.025
taxis GO:0042330 304 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.024
ubiquitin dependent protein catabolic process GO:0006511 78 0.024
axonogenesis GO:0007409 290 0.024
nucleobase containing compound catabolic process GO:0034655 165 0.024
regulation of programmed cell death GO:0043067 152 0.023
Human
mrna catabolic process GO:0006402 33 0.023
positive regulation of cellular biosynthetic process GO:0031328 316 0.023
cell proliferation GO:0008283 299 0.023
compound eye morphogenesis GO:0001745 249 0.023
detection of stimulus involved in sensory perception GO:0050906 92 0.022
body morphogenesis GO:0010171 2 0.022
cellular protein catabolic process GO:0044257 83 0.022
cellular homeostasis GO:0019725 80 0.022
oocyte differentiation GO:0009994 145 0.022
cellular response to dna damage stimulus GO:0006974 223 0.022
purine nucleotide metabolic process GO:0006163 146 0.022
meiotic cell cycle process GO:1903046 132 0.022
cytokinesis GO:0000910 90 0.021
sensory perception of mechanical stimulus GO:0050954 72 0.021
synaptic transmission GO:0007268 288 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.021
nucleoside phosphate metabolic process GO:0006753 162 0.021
proteolysis GO:0006508 192 0.021
regulation of response to external stimulus GO:0032101 115 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.021
single organism behavior GO:0044708 391 0.020
rhythmic process GO:0048511 106 0.020
response to abiotic stimulus GO:0009628 341 0.020
small molecule metabolic process GO:0044281 305 0.020
compound eye development GO:0048749 307 0.020
regulation of immune system process GO:0002682 176 0.020
regulation of protein localization GO:0032880 76 0.020
oocyte construction GO:0007308 112 0.020
centrosome organization GO:0051297 163 0.019
negative regulation of biosynthetic process GO:0009890 277 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.019
axon guidance GO:0007411 233 0.019
embryonic axis specification GO:0000578 107 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.019
positive regulation of developmental process GO:0051094 143 0.019
protein transport GO:0015031 155 0.019
Human Mouse
macromolecular complex assembly GO:0065003 256 0.019
Human
morphogenesis of an epithelium GO:0002009 276 0.019
endomembrane system organization GO:0010256 119 0.019
Mouse
negative regulation of cell death GO:0060548 81 0.019
mitotic nuclear division GO:0007067 213 0.018
positive regulation of macromolecule metabolic process GO:0010604 405 0.018
regulation of cellular catabolic process GO:0031329 157 0.018
organelle localization GO:0051640 148 0.018
mitotic sister chromatid segregation GO:0000070 87 0.018
organelle assembly GO:0070925 198 0.018
negative regulation of developmental process GO:0051093 201 0.018
positive regulation of signal transduction GO:0009967 223 0.018
embryonic development via the syncytial blastoderm GO:0001700 148 0.018
negative regulation of multicellular organismal process GO:0051241 142 0.017
regulation of cellular response to stress GO:0080135 89 0.017
carboxylic acid metabolic process GO:0019752 92 0.017
organophosphate metabolic process GO:0019637 195 0.017
purine containing compound catabolic process GO:0072523 112 0.017
nucleotide metabolic process GO:0009117 161 0.017
protein complex biogenesis GO:0070271 201 0.017
Human
protein modification by small protein conjugation GO:0032446 79 0.017
transmembrane transport GO:0055085 139 0.017
organonitrogen compound biosynthetic process GO:1901566 117 0.017
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.017
tripartite regional subdivision GO:0007351 103 0.017
response to external biotic stimulus GO:0043207 293 0.017
purine ribonucleotide catabolic process GO:0009154 109 0.017
cell motility GO:0048870 251 0.017
skin development GO:0043588 65 0.017
cognition GO:0050890 141 0.016
anatomical structure homeostasis GO:0060249 97 0.016
regulation of protein metabolic process GO:0051246 256 0.016
hematopoietic or lymphoid organ development GO:0048534 57 0.016
positive regulation of rna biosynthetic process GO:1902680 266 0.016
protein deubiquitination GO:0016579 17 0.016
neuron projection guidance GO:0097485 241 0.016
spermatogenesis GO:0007283 200 0.016
negative regulation of gene expression GO:0010629 387 0.016
epidermis development GO:0008544 65 0.016
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.016
sensory organ morphogenesis GO:0090596 260 0.016
molting cycle GO:0042303 56 0.016
protein catabolic process GO:0030163 101 0.016
positive regulation of growth GO:0045927 75 0.016
nucleus organization GO:0006997 45 0.016
negative regulation of cell cycle phase transition GO:1901988 103 0.015
regulation of ras protein signal transduction GO:0046578 93 0.015
positive regulation of signaling GO:0023056 243 0.015
rna localization GO:0006403 115 0.015
oxoacid metabolic process GO:0043436 103 0.015
nucleoside phosphate catabolic process GO:1901292 110 0.015
single organism membrane organization GO:0044802 93 0.015
Mouse
regulation of cell cycle process GO:0010564 181 0.015
nucleoside catabolic process GO:0009164 112 0.015
cell cell signaling involved in cell fate commitment GO:0045168 210 0.015
response to temperature stimulus GO:0009266 106 0.015
establishment of localization in cell GO:0051649 402 0.015
Mouse
multi multicellular organism process GO:0044706 123 0.015
peptidyl amino acid modification GO:0018193 105 0.014
Human
organic acid metabolic process GO:0006082 103 0.014
negative regulation of cell proliferation GO:0008285 69 0.014
immune system development GO:0002520 57 0.014
positive regulation of response to stimulus GO:0048584 323 0.014
positive regulation of transcription dna templated GO:0045893 266 0.014
cellular amide metabolic process GO:0043603 80 0.014
oocyte anterior posterior axis specification GO:0007314 72 0.014
cell maturation GO:0048469 144 0.014
humoral immune response GO:0006959 117 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
negative regulation of cell development GO:0010721 62 0.014
wnt signaling pathway GO:0016055 98 0.014
spermatid differentiation GO:0048515 114 0.014
positive regulation of rna metabolic process GO:0051254 271 0.014
establishment of protein localization GO:0045184 163 0.014
Human Mouse
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.014
glycosyl compound catabolic process GO:1901658 112 0.014
single organism catabolic process GO:0044712 228 0.013
mrna metabolic process GO:0016071 124 0.013
maintenance of location in cell GO:0051651 28 0.013
purine ribonucleoside metabolic process GO:0046128 127 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
negative regulation of cell differentiation GO:0045596 143 0.013
embryonic pattern specification GO:0009880 174 0.013
organelle fission GO:0048285 340 0.013
regulation of response to dna damage stimulus GO:2001020 23 0.013
blastoderm segmentation GO:0007350 159 0.013
vesicle mediated transport GO:0016192 381 0.013
Human
developmental growth GO:0048589 280 0.013
regulation of cell morphogenesis GO:0022604 163 0.013
regulation of rna splicing GO:0043484 69 0.013
nucleobase containing small molecule metabolic process GO:0055086 174 0.013
regulation of molecular function GO:0065009 217 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
cell growth GO:0016049 108 0.012
protein ubiquitination GO:0016567 70 0.012
regulation of small gtpase mediated signal transduction GO:0051056 93 0.012
eye photoreceptor cell differentiation GO:0001754 145 0.012
ribose phosphate metabolic process GO:0019693 145 0.012
embryo development ending in birth or egg hatching GO:0009792 152 0.012
anterior posterior axis specification embryo GO:0008595 103 0.012
rrna processing GO:0006364 3 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.012
ribonucleoside triphosphate catabolic process GO:0009203 108 0.012
establishment of organelle localization GO:0051656 122 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
cellular protein localization GO:0034613 160 0.012
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.012
macromolecular complex disassembly GO:0032984 37 0.012
cell death GO:0008219 279 0.012
Human
centrosome duplication GO:0051298 121 0.012
larval development GO:0002164 104 0.012
dendrite development GO:0016358 204 0.012
regulation of neuron projection development GO:0010975 69 0.012
mrna processing GO:0006397 104 0.012
microtubule polymerization or depolymerization GO:0031109 39 0.012
Human
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.012
membrane organization GO:0061024 112 0.011
Mouse
single organism carbohydrate metabolic process GO:0044723 72 0.011
response to organic substance GO:0010033 284 0.011
regulation of nervous system development GO:0051960 248 0.011
spindle elongation GO:0051231 83 0.011
regulation of nuclear division GO:0051783 58 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
maternal determination of anterior posterior axis embryo GO:0008358 74 0.011
actin filament based process GO:0030029 220 0.011
carbohydrate derivative metabolic process GO:1901135 217 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
olfactory behavior GO:0042048 97 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
peptide metabolic process GO:0006518 80 0.011
positive regulation of transport GO:0051050 92 0.011
Human
intracellular mrna localization GO:0008298 66 0.011
mitotic sister chromatid separation GO:0051306 30 0.011
response to nitrogen compound GO:1901698 90 0.011
mapk cascade GO:0000165 107 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
regulation of organelle organization GO:0033043 196 0.011
Human
cytoplasm organization GO:0007028 64 0.011
telencephalon development GO:0021537 2 0.011
male gamete generation GO:0048232 201 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.011
extrinsic apoptotic signaling pathway GO:0097191 1 0.011
reproductive system development GO:0061458 74 0.010
golgi organization GO:0007030 66 0.010
non sensory hair organization GO:0035316 47 0.010
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.010
mrna splicing via spliceosome GO:0000398 73 0.010
negative regulation of transcription dna templated GO:0045892 237 0.010
regulation of oocyte development GO:0060281 27 0.010
ribonucleoside catabolic process GO:0042454 112 0.010
protein targeting GO:0006605 64 0.010
negative regulation of programmed cell death GO:0043069 72 0.010
chromosome separation GO:0051304 42 0.010
negative regulation of mitotic cell cycle GO:0045930 109 0.010
nuclear division GO:0000280 332 0.010
central nervous system development GO:0007417 201 0.010
sex differentiation GO:0007548 81 0.010
hair cell differentiation GO:0035315 47 0.010
regulation of behavior GO:0050795 75 0.010
rna processing GO:0006396 147 0.010

CLIP-190 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.082
nervous system disease DOID:863 0 0.045
central nervous system disease DOID:331 0 0.012
disease of metabolism DOID:0014667 0 0.011