Drosophila melanogaster

20 known processes

Act42A (Dmel_CG12051)

Actin 42A

(Aliases: A,Actin/BAP47,C,BAP47,AFFX-Dros-ACTIN_M_r_at,CG12051,act 42A,Actin,Dmel\CG12051,Act,Act42a,act42A,actin)

Act42A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
digestive system development GO:0055123 149 0.258
digestive tract morphogenesis GO:0048546 127 0.234
cell division GO:0051301 248 0.213
tube development GO:0035295 244 0.192
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.166
catabolic process GO:0009056 409 0.153
humoral immune response GO:0006959 117 0.143
intracellular signal transduction GO:0035556 300 0.139
vesicle mediated transport GO:0016192 381 0.133
digestive tract development GO:0048565 149 0.132
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.119
organelle fission GO:0048285 340 0.116
death GO:0016265 284 0.116
dendrite development GO:0016358 204 0.114
organic substance catabolic process GO:1901575 308 0.108
cell migration GO:0016477 238 0.107
cell death GO:0008219 279 0.104
protein modification process GO:0036211 438 0.095
endocytosis GO:0006897 310 0.095
mesodermal cell migration GO:0008078 7 0.090
embryo development ending in birth or egg hatching GO:0009792 152 0.090
immune system process GO:0002376 347 0.089
localization of cell GO:0051674 257 0.088
response to abiotic stimulus GO:0009628 341 0.085
cell motility GO:0048870 251 0.084
positive regulation of rna biosynthetic process GO:1902680 266 0.082
positive regulation of rna metabolic process GO:0051254 271 0.081
dorsal ventral pattern formation GO:0009953 133 0.080
gastrulation GO:0007369 70 0.078
autophagic cell death GO:0048102 83 0.078
positive regulation of biosynthetic process GO:0009891 316 0.077
cytoskeleton dependent cytokinesis GO:0061640 81 0.077
gland morphogenesis GO:0022612 145 0.077
mesoderm development GO:0007498 78 0.077
embryonic morphogenesis GO:0048598 206 0.074
cytokinesis GO:0000910 90 0.073
defense response to fungus GO:0050832 48 0.071
muscle organ development GO:0007517 127 0.068
Fly
intracellular transport GO:0046907 228 0.068
Fly
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.068
defense response GO:0006952 300 0.068
wing disc pattern formation GO:0035222 66 0.067
negative regulation of signal transduction GO:0009968 206 0.066
immune response GO:0006955 246 0.065
male gamete generation GO:0048232 201 0.063
regulation of cellular catabolic process GO:0031329 157 0.063
negative regulation of cell communication GO:0010648 223 0.063
spermatogenesis GO:0007283 200 0.062
organonitrogen compound metabolic process GO:1901564 318 0.061
positive regulation of developmental process GO:0051094 143 0.059
tube morphogenesis GO:0035239 191 0.058
response to wounding GO:0009611 94 0.057
regulation of immune response GO:0050776 118 0.057
gland development GO:0048732 191 0.056
regulation of protein metabolic process GO:0051246 256 0.055
negative regulation of cell cycle GO:0045786 116 0.055
brain development GO:0007420 120 0.054
appendage morphogenesis GO:0035107 397 0.053
transition metal ion transport GO:0000041 16 0.053
histolysis GO:0007559 102 0.051
biological adhesion GO:0022610 138 0.051
positive regulation of signal transduction GO:0009967 223 0.051
regulation of cellular component biogenesis GO:0044087 201 0.050
regulation of localization GO:0032879 275 0.049
Fly
negative regulation of cellular catabolic process GO:0031330 34 0.049
regulation of response to external stimulus GO:0032101 115 0.048
positive regulation of cellular biosynthetic process GO:0031328 316 0.048
phenol containing compound metabolic process GO:0018958 57 0.048
cellular catabolic process GO:0044248 372 0.048
macromolecular complex assembly GO:0065003 256 0.048
negative regulation of signaling GO:0023057 219 0.047
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.046
developmental maturation GO:0021700 172 0.046
regulation of cellular protein metabolic process GO:0032268 243 0.045
axon guidance GO:0007411 233 0.044
anatomical structure homeostasis GO:0060249 97 0.043
forebrain development GO:0030900 2 0.043
protein localization GO:0008104 284 0.043
Fly
single organism catabolic process GO:0044712 228 0.043
salivary gland development GO:0007431 162 0.042
regulation of transport GO:0051049 181 0.042
Fly
salivary gland morphogenesis GO:0007435 145 0.042
ameboidal type cell migration GO:0001667 151 0.040
regulation of tube architecture open tracheal system GO:0035152 68 0.040
response to bacterium GO:0009617 198 0.040
mitotic spindle organization GO:0007052 220 0.040
mitotic cytokinesis GO:0000281 50 0.039
response to starvation GO:0042594 97 0.039
phosphorylation GO:0016310 294 0.039
chaeta development GO:0022416 97 0.038
taxis GO:0042330 304 0.038
positive regulation of gene expression GO:0010628 290 0.038
dendrite morphogenesis GO:0048813 199 0.038
negative regulation of cell cycle process GO:0010948 109 0.037
regulation of nervous system development GO:0051960 248 0.037
defense response to gram negative bacterium GO:0050829 94 0.037
appendage development GO:0048736 401 0.037
negative regulation of response to stimulus GO:0048585 258 0.037
regulation of cell differentiation GO:0045595 302 0.036
cellular protein modification process GO:0006464 438 0.035
tissue death GO:0016271 102 0.035
negative regulation of gene expression GO:0010629 387 0.035
central nervous system development GO:0007417 201 0.035
chemotaxis GO:0006935 249 0.035
response to other organism GO:0051707 293 0.034
nuclear division GO:0000280 332 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.034
organonitrogen compound catabolic process GO:1901565 128 0.033
carbohydrate derivative metabolic process GO:1901135 217 0.032
cilium organization GO:0044782 41 0.032
programmed cell death GO:0012501 257 0.032
regulation of cellular response to stress GO:0080135 89 0.032
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.032
secretion GO:0046903 109 0.032
response to radiation GO:0009314 155 0.032
positive regulation of macromolecule metabolic process GO:0010604 405 0.031
embryonic development via the syncytial blastoderm GO:0001700 148 0.031
salivary gland cell autophagic cell death GO:0035071 83 0.031
regulation of response to stress GO:0080134 200 0.031
cell proliferation GO:0008283 299 0.031
defense response to bacterium GO:0042742 178 0.031
ribonucleoside triphosphate metabolic process GO:0009199 119 0.031
developmental growth GO:0048589 280 0.030
response to extracellular stimulus GO:0009991 116 0.030
positive regulation of response to stimulus GO:0048584 323 0.030
regulation of cell cycle GO:0051726 291 0.030
response to nutrient levels GO:0031667 114 0.030
aging GO:0007568 143 0.030
sex differentiation GO:0007548 81 0.030
positive regulation of signaling GO:0023056 243 0.029
imaginal disc pattern formation GO:0007447 91 0.029
establishment of localization in cell GO:0051649 402 0.029
Fly
positive regulation of transport GO:0051050 92 0.029
Fly
mesodermal cell fate specification GO:0007501 2 0.029
tissue morphogenesis GO:0048729 297 0.029
regulation of behavior GO:0050795 75 0.029
protein import into nucleus GO:0006606 51 0.029
Fly
regulation of catabolic process GO:0009894 170 0.029
regulation of cell cycle phase transition GO:1901987 130 0.028
protein phosphorylation GO:0006468 169 0.028
regulation of phosphate metabolic process GO:0019220 210 0.028
embryonic pattern specification GO:0009880 174 0.027
regulation of cellular amide metabolic process GO:0034248 39 0.027
apoptotic process GO:0006915 159 0.027
transcription from rna polymerase ii promoter GO:0006366 368 0.027
cell cell signaling involved in cell fate commitment GO:0045168 210 0.026
carbohydrate derivative catabolic process GO:1901136 118 0.026
response to light stimulus GO:0009416 124 0.026
neuron projection guidance GO:0097485 241 0.026
regulation of vesicle mediated transport GO:0060627 59 0.026
small molecule metabolic process GO:0044281 305 0.026
protein complex assembly GO:0006461 200 0.026
regulation of immune system process GO:0002682 176 0.025
maintenance of location GO:0051235 73 0.025
endomembrane system organization GO:0010256 119 0.025
cell adhesion GO:0007155 136 0.025
protein maturation GO:0051604 71 0.025
gonad development GO:0008406 50 0.025
proteolysis GO:0006508 192 0.025
response to biotic stimulus GO:0009607 294 0.024
leg disc morphogenesis GO:0007478 80 0.024
mitotic g2 dna damage checkpoint GO:0007095 69 0.024
stem cell differentiation GO:0048863 117 0.024
salivary gland histolysis GO:0035070 88 0.024
innate immune response GO:0045087 144 0.023
morphogenesis of an epithelium GO:0002009 276 0.023
mesoderm formation GO:0001707 21 0.023
regulation of neurogenesis GO:0050767 158 0.023
meiotic cell cycle process GO:1903046 132 0.023
regionalization GO:0003002 416 0.023
cellular protein localization GO:0034613 160 0.023
Fly
positive regulation of cell motility GO:2000147 3 0.023
single organism cellular localization GO:1902580 180 0.022
Fly
regulation of cell death GO:0010941 173 0.022
establishment of organelle localization GO:0051656 122 0.022
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.022
cellular component assembly involved in morphogenesis GO:0010927 151 0.022
positive regulation of nervous system development GO:0051962 69 0.022
homeostatic process GO:0042592 199 0.022
regulation of cell shape GO:0008360 113 0.021
negative regulation of cellular metabolic process GO:0031324 382 0.021
regulation of cell development GO:0060284 215 0.021
organic acid metabolic process GO:0006082 103 0.021
mitotic cell cycle phase transition GO:0044772 138 0.021
skeletal muscle organ development GO:0060538 48 0.021
Fly
positive regulation of cellular component biogenesis GO:0044089 80 0.021
exocrine system development GO:0035272 162 0.021
regulation of molecular function GO:0065009 217 0.021
response to external biotic stimulus GO:0043207 293 0.021
antimicrobial peptide production GO:0002775 46 0.021
negative regulation of mitotic cell cycle GO:0045930 109 0.021
telencephalon development GO:0021537 2 0.020
developmental programmed cell death GO:0010623 138 0.020
negative regulation of catabolic process GO:0009895 36 0.020
response to oxygen containing compound GO:1901700 200 0.020
protein complex biogenesis GO:0070271 201 0.020
actin cytoskeleton organization GO:0030036 206 0.020
hindbrain development GO:0030902 2 0.020
determination of adult lifespan GO:0008340 137 0.020
mitotic nuclear division GO:0007067 213 0.020
cellular macromolecular complex assembly GO:0034622 153 0.020
purine containing compound metabolic process GO:0072521 155 0.020
cell projection assembly GO:0030031 94 0.020
negative regulation of cellular protein metabolic process GO:0032269 85 0.019
cognition GO:0050890 141 0.019
establishment of protein localization GO:0045184 163 0.019
Fly
arp2 3 complex mediated actin nucleation GO:0034314 3 0.019
protein catabolic process GO:0030163 101 0.019
positive regulation of phagocytosis GO:0050766 3 0.019
wing disc dorsal ventral pattern formation GO:0048190 47 0.019
negative regulation of protein metabolic process GO:0051248 85 0.019
regulation of notch signaling pathway GO:0008593 100 0.019
glycosyl compound catabolic process GO:1901658 112 0.019
regulation of anatomical structure morphogenesis GO:0022603 242 0.019
cellular homeostasis GO:0019725 80 0.019
nucleoside metabolic process GO:0009116 127 0.019
purine containing compound catabolic process GO:0072523 112 0.019
response to lipopolysaccharide GO:0032496 4 0.019
regulation of endocytosis GO:0030100 37 0.019
organelle localization GO:0051640 148 0.019
reproductive system development GO:0061458 74 0.018
response to fungus GO:0009620 50 0.018
notch signaling pathway GO:0007219 120 0.018
positive regulation of developmental growth GO:0048639 62 0.018
antibacterial humoral response GO:0019731 44 0.018
nucleoside phosphate metabolic process GO:0006753 162 0.018
phagocytosis GO:0006909 215 0.018
single organism nuclear import GO:1902593 51 0.018
Fly
response to endogenous stimulus GO:0009719 119 0.018
chromosome organization GO:0051276 360 0.018
regulation of mitotic cell cycle GO:0007346 190 0.018
regulation of multicellular organismal development GO:2000026 414 0.018
regulation of organ formation GO:0003156 3 0.018
antimicrobial peptide biosynthetic process GO:0002777 38 0.017
regulation of intracellular signal transduction GO:1902531 236 0.017
negative regulation of proteolysis GO:0045861 31 0.017
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.017
respiratory system development GO:0060541 213 0.017
immune effector process GO:0002252 98 0.017
wing disc morphogenesis GO:0007472 344 0.017
positive regulation of cell communication GO:0010647 250 0.017
response to hypoxia GO:0001666 53 0.017
regulation of cell projection organization GO:0031344 92 0.017
aromatic compound catabolic process GO:0019439 166 0.017
establishment of protein localization to organelle GO:0072594 62 0.017
Fly
spindle organization GO:0007051 253 0.017
regulation of protein modification process GO:0031399 112 0.017
larval development GO:0002164 104 0.017
cellular amino acid metabolic process GO:0006520 61 0.017
cellular response to lipopolysaccharide GO:0071222 3 0.016
regulation of cell morphogenesis GO:0022604 163 0.016
negative regulation of epithelial cell proliferation GO:0050680 4 0.016
negative regulation of biosynthetic process GO:0009890 277 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.016
purine ribonucleoside catabolic process GO:0046130 112 0.016
cellular response to biotic stimulus GO:0071216 4 0.016
regulation of protein localization GO:0032880 76 0.016
Fly
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.016
antimicrobial humoral response GO:0019730 99 0.016
heart morphogenesis GO:0003007 32 0.016
regulation of anatomical structure size GO:0090066 163 0.016
positive regulation of nucleic acid templated transcription GO:1903508 266 0.016
nucleoside catabolic process GO:0009164 112 0.016
cellular response to molecule of bacterial origin GO:0071219 3 0.016
striated muscle cell differentiation GO:0051146 90 0.016
Fly
body morphogenesis GO:0010171 2 0.015
regulation of cell cycle process GO:0010564 181 0.015
detection of abiotic stimulus GO:0009582 66 0.015
divalent inorganic cation transport GO:0072511 30 0.015
regulation of antimicrobial peptide production GO:0002784 44 0.015
regulation of actin cytoskeleton organization GO:0032956 42 0.015
g protein coupled receptor signaling pathway GO:0007186 136 0.015
camera type eye development GO:0043010 4 0.015
regulation of cellular component size GO:0032535 98 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.015
negative regulation of developmental process GO:0051093 201 0.015
connective tissue development GO:0061448 3 0.015
regulation of synapse structure and activity GO:0050803 128 0.014
Fly
positive regulation of apoptotic signaling pathway GO:2001235 4 0.014
purine nucleoside catabolic process GO:0006152 112 0.014
signal transduction by phosphorylation GO:0023014 107 0.014
protein transport GO:0015031 155 0.014
Fly
regulation of multi organism process GO:0043900 131 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
regulation of defense response to bacterium GO:1900424 30 0.014
imaginal disc derived appendage morphogenesis GO:0035114 395 0.014
positive regulation of cellular protein metabolic process GO:0032270 118 0.014
regulation of intracellular transport GO:0032386 64 0.014
Fly
wound healing GO:0042060 75 0.014
ribonucleoside catabolic process GO:0042454 112 0.014
neural retina development GO:0003407 4 0.014
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
regulation of neuron differentiation GO:0045664 103 0.014
nuclear transport GO:0051169 72 0.014
Fly
negative regulation of multicellular organismal process GO:0051241 142 0.013
translation GO:0006412 69 0.013
imaginal disc derived appendage development GO:0048737 399 0.013
negative regulation of protein processing GO:0010955 31 0.013
regulation of catalytic activity GO:0050790 185 0.013
morphogenesis of embryonic epithelium GO:0016331 94 0.013
formation of primary germ layer GO:0001704 24 0.013
regulation of cellular component movement GO:0051270 42 0.013
negative regulation of cellular component organization GO:0051129 108 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.013
actin filament based process GO:0030029 220 0.013
cell junction assembly GO:0034329 42 0.013
cell cycle checkpoint GO:0000075 95 0.013
protein processing GO:0016485 68 0.013
amine metabolic process GO:0009308 12 0.013
positive regulation of cell migration GO:0030335 2 0.013
nucleobase containing compound catabolic process GO:0034655 165 0.013
regulation of protein processing GO:0070613 32 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
nucleotide metabolic process GO:0009117 161 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
regulation of mitotic cell cycle phase transition GO:1901990 130 0.012
imaginal disc derived wing morphogenesis GO:0007476 337 0.012
purine nucleoside metabolic process GO:0042278 127 0.012
purine ribonucleotide catabolic process GO:0009154 109 0.012
blastoderm segmentation GO:0007350 159 0.012
mitotic cell cycle checkpoint GO:0007093 88 0.012
peptide biosynthetic process GO:0043043 42 0.012
response to heat GO:0009408 63 0.012
retina development in camera type eye GO:0060041 4 0.012
maintenance of epithelial integrity open tracheal system GO:0035160 12 0.012
regulation of programmed cell death GO:0043067 152 0.012
mesoderm morphogenesis GO:0048332 22 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
spermatid development GO:0007286 98 0.012
cilium morphogenesis GO:0060271 39 0.012
peptide metabolic process GO:0006518 80 0.012
single organism intracellular transport GO:1902582 207 0.012
Fly
regulation of locomotion GO:0040012 42 0.012
carboxylic acid metabolic process GO:0019752 92 0.012
neurological system process GO:0050877 358 0.012
embryonic axis specification GO:0000578 107 0.012
negative regulation of cell cycle phase transition GO:1901988 103 0.012
receptor mediated endocytosis GO:0006898 21 0.012
cytoplasmic transport GO:0016482 130 0.012
Fly
mushroom body development GO:0016319 70 0.012
chaeta morphogenesis GO:0008407 42 0.012
multicellular organismal reproductive behavior GO:0033057 110 0.011
production of molecular mediator of immune response GO:0002440 46 0.011
chromosome segregation GO:0007059 157 0.011
multicellular organismal aging GO:0010259 140 0.011
lateral inhibition GO:0046331 206 0.011
cellular protein complex assembly GO:0043623 71 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
nucleotide catabolic process GO:0009166 109 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
limb morphogenesis GO:0035108 1 0.011
cellular component disassembly GO:0022411 46 0.011
compound eye development GO:0048749 307 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
positive regulation of transcription dna templated GO:0045893 266 0.011
organophosphate catabolic process GO:0046434 112 0.011
heterocycle catabolic process GO:0046700 166 0.011
single organism cell adhesion GO:0098602 47 0.011
nucleocytoplasmic transport GO:0006913 72 0.011
Fly
regulation of wnt signaling pathway GO:0030111 68 0.011
negative regulation of cell proliferation GO:0008285 69 0.011
eye development GO:0001654 323 0.011
extrinsic apoptotic signaling pathway GO:0097191 1 0.010
post embryonic appendage morphogenesis GO:0035120 385 0.010
cellular response to external stimulus GO:0071496 66 0.010
asymmetric cell division GO:0008356 37 0.010
chromatin organization GO:0006325 207 0.010
regulation of hydrolase activity GO:0051336 97 0.010
positive regulation of multicellular organismal process GO:0051240 143 0.010
cell cycle phase transition GO:0044770 140 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.010
protein secretion GO:0009306 45 0.010
multicellular organismal homeostasis GO:0048871 41 0.010
axonogenesis GO:0007409 290 0.010

Act42A disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.144
musculoskeletal system disease DOID:17 0 0.144
muscular disease DOID:0080000 0 0.014
muscle tissue disease DOID:66 0 0.014
myopathy DOID:423 0 0.011