Drosophila melanogaster

0 known processes

TwdlO (Dmel_CG6452)

TweedleO

(Aliases: Dmel\CG6452,CG6452)

TwdlO biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organonitrogen compound metabolic process GO:1901564 318 0.042
catabolic process GO:0009056 409 0.038
small molecule metabolic process GO:0044281 305 0.037
single organism biosynthetic process GO:0044711 206 0.037
cellular catabolic process GO:0044248 372 0.033
cellular protein modification process GO:0006464 438 0.033
response to abiotic stimulus GO:0009628 341 0.031
carbohydrate derivative metabolic process GO:1901135 217 0.031
organic substance catabolic process GO:1901575 308 0.029
epithelial cell development GO:0002064 274 0.028
regulation of localization GO:0032879 275 0.028
vesicle mediated transport GO:0016192 381 0.027
cholesterol homeostasis GO:0042632 3 0.027
protein modification process GO:0036211 438 0.027
regulation of cell cycle GO:0051726 291 0.027
phagocytosis GO:0006909 215 0.026
establishment of localization in cell GO:0051649 402 0.026
regulation of multicellular organismal development GO:2000026 414 0.026
positive regulation of nucleic acid templated transcription GO:1903508 266 0.025
immune system process GO:0002376 347 0.025
regulation of cellular ketone metabolic process GO:0010565 3 0.024
cell proliferation GO:0008283 299 0.024
sterol homeostasis GO:0055092 4 0.024
camera type eye development GO:0043010 4 0.024
organic acid metabolic process GO:0006082 103 0.024
imaginal disc derived wing morphogenesis GO:0007476 337 0.023
cellular amino acid metabolic process GO:0006520 61 0.023
compound eye development GO:0048749 307 0.023
imaginal disc derived appendage morphogenesis GO:0035114 395 0.023
negative regulation of gene expression GO:0010629 387 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.022
single organism catabolic process GO:0044712 228 0.022
macromolecular complex assembly GO:0065003 256 0.022
oxoacid metabolic process GO:0043436 103 0.022
endocytosis GO:0006897 310 0.022
positive regulation of response to stimulus GO:0048584 323 0.022
positive regulation of cellular biosynthetic process GO:0031328 316 0.022
protein complex biogenesis GO:0070271 201 0.022
imaginal disc derived appendage development GO:0048737 399 0.022
appendage morphogenesis GO:0035107 397 0.021
appendage development GO:0048736 401 0.021
lipid metabolic process GO:0006629 121 0.021
response to lipopolysaccharide GO:0032496 4 0.021
positive regulation of macromolecule metabolic process GO:0010604 405 0.021
carbohydrate derivative biosynthetic process GO:1901137 85 0.021
intracellular signal transduction GO:0035556 300 0.021
organophosphate metabolic process GO:0019637 195 0.020
regulation of cell differentiation GO:0045595 302 0.020
developmental growth GO:0048589 280 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.020
carboxylic acid metabolic process GO:0019752 92 0.020
lateral inhibition GO:0046331 206 0.020
wing disc morphogenesis GO:0007472 344 0.020
positive regulation of biosynthetic process GO:0009891 316 0.020
regulation of cellular amine metabolic process GO:0033238 3 0.020
body morphogenesis GO:0010171 2 0.020
Fly
cell death GO:0008219 279 0.019
monocarboxylic acid transport GO:0015718 3 0.019
regulation of sequestering of triglyceride GO:0010889 3 0.019
epithelial cell differentiation GO:0030855 322 0.019
positive regulation of gene expression GO:0010628 290 0.019
phosphorylation GO:0016310 294 0.019
cellular ketone metabolic process GO:0042180 24 0.019
cellular lipid metabolic process GO:0044255 83 0.019
protein complex assembly GO:0006461 200 0.019
amine metabolic process GO:0009308 12 0.019
positive regulation of signal transduction GO:0009967 223 0.018
anion homeostasis GO:0055081 3 0.018
transcription from rna polymerase ii promoter GO:0006366 368 0.018
death GO:0016265 284 0.018
cell division GO:0051301 248 0.018
compound eye morphogenesis GO:0001745 249 0.018
gland development GO:0048732 191 0.018
cellular amine metabolic process GO:0044106 12 0.018
response to copper ion GO:0046688 4 0.018
transmembrane transport GO:0055085 139 0.018
neutral lipid biosynthetic process GO:0046460 2 0.018
eye morphogenesis GO:0048592 260 0.018
response to organic substance GO:0010033 284 0.018
eye development GO:0001654 323 0.017
ethanolamine containing compound metabolic process GO:0042439 4 0.017
organic substance transport GO:0071702 257 0.017
regulation of transport GO:0051049 181 0.017
post embryonic appendage morphogenesis GO:0035120 385 0.017
cellular response to chemical stimulus GO:0070887 199 0.017
triglyceride biosynthetic process GO:0019432 2 0.017
positive regulation of signaling GO:0023056 243 0.017
forebrain development GO:0030900 2 0.017
acylglycerol catabolic process GO:0046464 3 0.017
actin filament based process GO:0030029 220 0.017
organophosphate catabolic process GO:0046434 112 0.017
cholesterol transport GO:0030301 2 0.017
positive regulation of cell communication GO:0010647 250 0.017
growth GO:0040007 359 0.017
cellular response to organic substance GO:0071310 132 0.017
programmed cell death GO:0012501 257 0.016
single organism intracellular transport GO:1902582 207 0.016
ion transport GO:0006811 145 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
response to oxygen containing compound GO:1901700 200 0.016
regulation of mitotic cell cycle GO:0007346 190 0.016
response to biotic stimulus GO:0009607 294 0.016
negative regulation of developmental process GO:0051093 201 0.016
positive regulation of lipid storage GO:0010884 4 0.016
proteolysis GO:0006508 192 0.016
regulation of cellular component biogenesis GO:0044087 201 0.015
spindle organization GO:0007051 253 0.015
organonitrogen compound biosynthetic process GO:1901566 117 0.015
defense response GO:0006952 300 0.015
homeostatic process GO:0042592 199 0.015
response to other organism GO:0051707 293 0.015
regionalization GO:0003002 416 0.015
regulation of cell cycle process GO:0010564 181 0.015
negative regulation of cellular metabolic process GO:0031324 382 0.015
chromosome organization GO:0051276 360 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
taxis GO:0042330 304 0.015
response to monosaccharide GO:0034284 4 0.015
response to bacterium GO:0009617 198 0.015
intracellular transport GO:0046907 228 0.015
response to external biotic stimulus GO:0043207 293 0.015
ras protein signal transduction GO:0007265 88 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.015
protein localization GO:0008104 284 0.015
organelle fission GO:0048285 340 0.014
immune response activating signal transduction GO:0002757 2 0.014
negative regulation of biosynthetic process GO:0009890 277 0.014
regulation of intracellular signal transduction GO:1902531 236 0.014
carbohydrate metabolic process GO:0005975 82 0.014
response to extracellular stimulus GO:0009991 116 0.014
phosphatidic acid metabolic process GO:0046473 1 0.014
single organism carbohydrate metabolic process GO:0044723 72 0.014
response to nutrient levels GO:0031667 114 0.014
organic cyclic compound catabolic process GO:1901361 168 0.014
sensory organ morphogenesis GO:0090596 260 0.014
small gtpase mediated signal transduction GO:0007264 88 0.014
vitamin metabolic process GO:0006766 2 0.014
aromatic compound catabolic process GO:0019439 166 0.014
regulation of developmental growth GO:0048638 174 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.014
regulation of cellular protein metabolic process GO:0032268 243 0.014
androgen metabolic process GO:0008209 1 0.014
retina development in camera type eye GO:0060041 4 0.014
positive regulation of rna biosynthetic process GO:1902680 266 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
apoptotic process GO:0006915 159 0.013
negative regulation of response to stimulus GO:0048585 258 0.013
acylglycerol biosynthetic process GO:0046463 2 0.013
telencephalon development GO:0021537 2 0.013
regulation of molecular function GO:0065009 217 0.013
protein phosphorylation GO:0006468 169 0.013
positive regulation of transcription dna templated GO:0045893 266 0.013
rhythmic process GO:0048511 106 0.013
cellular response to dna damage stimulus GO:0006974 223 0.013
kidney development GO:0001822 3 0.013
macromolecule catabolic process GO:0009057 161 0.013
cellular component assembly involved in morphogenesis GO:0010927 151 0.013
regulation of lipid transport GO:0032368 3 0.013
phosphatidylethanolamine metabolic process GO:0046337 1 0.013
columnar cuboidal epithelial cell development GO:0002066 249 0.013
mitotic nuclear division GO:0007067 213 0.013
neutral lipid catabolic process GO:0046461 3 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.013
autophagic cell death GO:0048102 83 0.013
defense response to bacterium GO:0042742 178 0.013
negative regulation of rna metabolic process GO:0051253 251 0.013
phospholipid homeostasis GO:0055091 1 0.013
developmental maturation GO:0021700 172 0.013
adult behavior GO:0030534 137 0.013
wnt signaling pathway GO:0016055 98 0.013
regulation of cell death GO:0010941 173 0.013
positive regulation of cellular component organization GO:0051130 156 0.013
nucleobase containing small molecule metabolic process GO:0055086 174 0.013
positive regulation of transport GO:0051050 92 0.013
dorsal ventral pattern formation GO:0009953 133 0.013
notch signaling pathway GO:0007219 120 0.012
ovarian follicle cell development GO:0030707 248 0.012
regulation of nervous system development GO:0051960 248 0.012
response to organophosphorus GO:0046683 2 0.012
positive regulation of cellular component biogenesis GO:0044089 80 0.012
connective tissue development GO:0061448 3 0.012
glycoprotein metabolic process GO:0009100 41 0.012
regulation of growth GO:0040008 233 0.012
cellular protein localization GO:0034613 160 0.012
eye photoreceptor cell differentiation GO:0001754 145 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
compound eye photoreceptor cell differentiation GO:0001751 140 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
positive regulation of cell motility GO:2000147 3 0.012
hematopoietic progenitor cell differentiation GO:0002244 1 0.012
endomembrane system organization GO:0010256 119 0.012
gene silencing GO:0016458 138 0.012
nuclear division GO:0000280 332 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
response to wounding GO:0009611 94 0.012
immune response regulating signaling pathway GO:0002764 2 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.012
central nervous system development GO:0007417 201 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
regulation of phosphorylation GO:0042325 147 0.012
secondary metabolic process GO:0019748 75 0.012
negative regulation of nucleic acid templated transcription GO:1903507 240 0.012
hormone catabolic process GO:0042447 3 0.012
regulation of catalytic activity GO:0050790 185 0.012
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
response to organonitrogen compound GO:0010243 75 0.012
ion transmembrane transport GO:0034220 122 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
fat soluble vitamin metabolic process GO:0006775 1 0.012
neurological system process GO:0050877 358 0.012
neuron projection guidance GO:0097485 241 0.012
developmental programmed cell death GO:0010623 138 0.012
chemotaxis GO:0006935 249 0.012
triglyceride catabolic process GO:0019433 3 0.012
heterocycle catabolic process GO:0046700 166 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
regulation of protein metabolic process GO:0051246 256 0.012
embryonic morphogenesis GO:0048598 206 0.012
regulation of programmed cell death GO:0043067 152 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
single organism behavior GO:0044708 391 0.011
positive regulation of molecular function GO:0044093 136 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
negative regulation of signal transduction GO:0009968 206 0.011
l amino acid import GO:0043092 2 0.011
regulation of sterol transport GO:0032371 1 0.011
lipid localization GO:0010876 54 0.011
histolysis GO:0007559 102 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
pigmentation GO:0043473 75 0.011
camera type eye morphogenesis GO:0048593 2 0.011
nucleotide metabolic process GO:0009117 161 0.011
synaptic transmission GO:0007268 288 0.011
regulation of apoptotic process GO:0042981 130 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
cellularization GO:0007349 90 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.011
pigment metabolic process GO:0042440 84 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
chemical homeostasis GO:0048878 92 0.011
regulation of cell development GO:0060284 215 0.011
salivary gland development GO:0007431 162 0.011
mapk cascade GO:0000165 107 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.011
axon guidance GO:0007411 233 0.011
positive regulation of hydrolase activity GO:0051345 78 0.011
glycoprotein biosynthetic process GO:0009101 41 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
hindbrain development GO:0030902 2 0.011
wound healing GO:0042060 75 0.011
dendrite development GO:0016358 204 0.011
water homeostasis GO:0030104 3 0.011
exocrine system development GO:0035272 162 0.011
male gamete generation GO:0048232 201 0.011
humoral immune response GO:0006959 117 0.011
regulation of steroid metabolic process GO:0019218 2 0.011
positive regulation of rna metabolic process GO:0051254 271 0.010
salivary gland morphogenesis GO:0007435 145 0.010
purine containing compound metabolic process GO:0072521 155 0.010
regulation of catabolic process GO:0009894 170 0.010
organelle assembly GO:0070925 198 0.010
regulation of gene expression epigenetic GO:0040029 128 0.010
cellular macromolecule localization GO:0070727 220 0.010
cellular response to lipopolysaccharide GO:0071222 3 0.010
alditol phosphate metabolic process GO:0052646 2 0.010
positive regulation of catabolic process GO:0009896 105 0.010
enzyme linked receptor protein signaling pathway GO:0007167 179 0.010
gland morphogenesis GO:0022612 145 0.010
regulation of anatomical structure morphogenesis GO:0022603 242 0.010
activation of innate immune response GO:0002218 4 0.010
axis specification GO:0009798 167 0.010
rna processing GO:0006396 147 0.010
cellular macromolecular complex assembly GO:0034622 153 0.010
carbohydrate derivative catabolic process GO:1901136 118 0.010
positive regulation of phosphorus metabolic process GO:0010562 139 0.010
axonogenesis GO:0007409 290 0.010
positive regulation of intracellular signal transduction GO:1902533 116 0.010

TwdlO disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.046
disease of metabolism DOID:0014667 0 0.021
inherited metabolic disorder DOID:655 0 0.017
nervous system disease DOID:863 0 0.017
familial hyperlipidemia DOID:1168 0 0.016
lipid metabolism disorder DOID:3146 0 0.016
acquired metabolic disease DOID:0060158 0 0.015
diabetes mellitus DOID:9351 0 0.015
carbohydrate metabolism disease DOID:0050013 0 0.015
glucose metabolism disease DOID:4194 0 0.015
type 2 diabetes mellitus DOID:9352 0 0.014
familial hypertriglyceridemia DOID:0050527 0 0.013
musculoskeletal system disease DOID:17 0 0.012
cardiovascular system disease DOID:1287 0 0.012
hair disease DOID:421 0 0.011
integumentary system disease DOID:16 0 0.011
hypotrichosis DOID:4535 0 0.011
sensory system disease DOID:0050155 0 0.011
familial lipoprotein lipase deficiency DOID:14118 0 0.011