Drosophila melanogaster

77 known processes

Scr (Dmel_CG1030)

Sex combs reduced

(Aliases: BG:DS07876.2,CG1030,l(3)84Af,DmScr,Dmel\CG1030,scr,Msc,SCR)

Scr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
eye development GO:0001654 323 0.090
single organism behavior GO:0044708 391 0.080
neurological system process GO:0050877 358 0.072
sensory perception GO:0007600 196 0.060
mating GO:0007618 120 0.056
regionalization GO:0003002 416 0.054
Fly
organonitrogen compound metabolic process GO:1901564 318 0.053
sensory perception of chemical stimulus GO:0007606 116 0.052
positive regulation of cellular biosynthetic process GO:0031328 316 0.051
post embryonic appendage morphogenesis GO:0035120 385 0.047
dendrite development GO:0016358 204 0.047
small molecule metabolic process GO:0044281 305 0.046
morphogenesis of an epithelium GO:0002009 276 0.045
compound eye development GO:0048749 307 0.044
leg disc development GO:0035218 92 0.044
response to organic substance GO:0010033 284 0.043
appendage morphogenesis GO:0035107 397 0.042
appendage development GO:0048736 401 0.042
eye morphogenesis GO:0048592 260 0.041
imaginal disc derived appendage morphogenesis GO:0035114 395 0.040
head development GO:0060322 135 0.040
Fly
positive regulation of biosynthetic process GO:0009891 316 0.039
positive regulation of macromolecule metabolic process GO:0010604 405 0.039
imaginal disc derived appendage development GO:0048737 399 0.039
positive regulation of gene expression GO:0010628 290 0.038
protein localization GO:0008104 284 0.038
detection of stimulus GO:0051606 156 0.038
sensory organ morphogenesis GO:0090596 260 0.037
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.037
imaginal disc derived wing morphogenesis GO:0007476 337 0.037
endocytosis GO:0006897 310 0.036
negative regulation of developmental process GO:0051093 201 0.036
negative regulation of response to stimulus GO:0048585 258 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.034
wing disc morphogenesis GO:0007472 344 0.034
segmentation GO:0035282 207 0.033
Fly
multi organism behavior GO:0051705 175 0.032
vesicle mediated transport GO:0016192 381 0.032
segment specification GO:0007379 33 0.032
Fly
respiratory system development GO:0060541 213 0.031
regulation of anatomical structure size GO:0090066 163 0.030
compound eye morphogenesis GO:0001745 249 0.030
carbohydrate derivative metabolic process GO:1901135 217 0.030
biological adhesion GO:0022610 138 0.029
taxis GO:0042330 304 0.029
defense response GO:0006952 300 0.029
open tracheal system development GO:0007424 204 0.029
positive regulation of rna biosynthetic process GO:1902680 266 0.029
tissue morphogenesis GO:0048729 297 0.028
negative regulation of rna metabolic process GO:0051253 251 0.028
Fly
phagocytosis GO:0006909 215 0.028
gland morphogenesis GO:0022612 145 0.028
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.028
Fly
intracellular signal transduction GO:0035556 300 0.028
cellular response to chemical stimulus GO:0070887 199 0.027
central nervous system development GO:0007417 201 0.027
Fly
dendrite morphogenesis GO:0048813 199 0.027
cell death GO:0008219 279 0.027
Fly
detection of chemical stimulus GO:0009593 93 0.027
nucleobase containing small molecule metabolic process GO:0055086 174 0.027
positive regulation of transcription dna templated GO:0045893 266 0.027
response to abiotic stimulus GO:0009628 341 0.027
transcription from rna polymerase ii promoter GO:0006366 368 0.026
cell motility GO:0048870 251 0.026
single organism biosynthetic process GO:0044711 206 0.026
catabolic process GO:0009056 409 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.026
imaginal disc derived leg morphogenesis GO:0007480 80 0.026
negative regulation of multicellular organismal process GO:0051241 142 0.026
regulation of anatomical structure morphogenesis GO:0022603 242 0.026
Fly
regulation of intracellular signal transduction GO:1902531 236 0.026
salivary gland morphogenesis GO:0007435 145 0.026
blastoderm segmentation GO:0007350 159 0.025
Fly
response to oxygen containing compound GO:1901700 200 0.025
nucleoside phosphate metabolic process GO:0006753 162 0.025
organophosphate metabolic process GO:0019637 195 0.025
mating behavior GO:0007617 106 0.025
embryonic morphogenesis GO:0048598 206 0.025
cellular catabolic process GO:0044248 372 0.024
axonogenesis GO:0007409 290 0.024
regulation of cell development GO:0060284 215 0.024
Fly
negative regulation of rna biosynthetic process GO:1902679 240 0.024
Fly
nuclear division GO:0000280 332 0.024
embryonic pattern specification GO:0009880 174 0.024
Fly
single organism catabolic process GO:0044712 228 0.024
gland development GO:0048732 191 0.024
cellular protein modification process GO:0006464 438 0.024
positive regulation of cell communication GO:0010647 250 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.023
purine ribonucleotide metabolic process GO:0009150 145 0.023
positive regulation of nucleic acid templated transcription GO:1903508 266 0.023
response to external biotic stimulus GO:0043207 293 0.023
adult behavior GO:0030534 137 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.023
Fly
exocrine system development GO:0035272 162 0.023
organic substance transport GO:0071702 257 0.023
death GO:0016265 284 0.023
Fly
regulation of nervous system development GO:0051960 248 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.023
mesoderm development GO:0007498 78 0.023
body morphogenesis GO:0010171 2 0.023
regulation of multicellular organismal development GO:2000026 414 0.023
response to biotic stimulus GO:0009607 294 0.022
tissue death GO:0016271 102 0.022
multi multicellular organism process GO:0044706 123 0.022
neuron recognition GO:0008038 101 0.022
cell cell signaling involved in cell fate commitment GO:0045168 210 0.022
lateral inhibition GO:0046331 206 0.022
establishment of protein localization GO:0045184 163 0.022
tube development GO:0035295 244 0.021
response to other organism GO:0051707 293 0.021
detection of stimulus involved in sensory perception GO:0050906 92 0.021
camera type eye development GO:0043010 4 0.021
regulation of molecular function GO:0065009 217 0.021
cell adhesion GO:0007155 136 0.021
regulation of cell death GO:0010941 173 0.021
Fly
negative regulation of biosynthetic process GO:0009890 277 0.021
Fly
positive regulation of rna metabolic process GO:0051254 271 0.021
localization of cell GO:0051674 257 0.021
actin cytoskeleton organization GO:0030036 206 0.021
organelle fission GO:0048285 340 0.020
positive regulation of signal transduction GO:0009967 223 0.020
forebrain development GO:0030900 2 0.020
negative regulation of cellular biosynthetic process GO:0031327 277 0.020
Fly
nucleotide metabolic process GO:0009117 161 0.020
anterior posterior pattern specification GO:0009952 136 0.020
cellular macromolecule localization GO:0070727 220 0.020
locomotory behavior GO:0007626 176 0.020
circulatory system development GO:0072359 82 0.020
negative regulation of cellular metabolic process GO:0031324 382 0.020
Fly
regulation of defense response GO:0031347 102 0.019
growth GO:0040007 359 0.019
response to lipopolysaccharide GO:0032496 4 0.019
cation transport GO:0006812 110 0.019
kidney development GO:0001822 3 0.019
ion transport GO:0006811 145 0.019
ribonucleotide metabolic process GO:0009259 145 0.019
regulation of localization GO:0032879 275 0.019
developmental growth GO:0048589 280 0.019
purine nucleotide metabolic process GO:0006163 146 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.018
Fly
positive regulation of response to stimulus GO:0048584 323 0.018
regulation of transport GO:0051049 181 0.018
reproductive behavior GO:0019098 122 0.018
male courtship behavior GO:0008049 63 0.018
purine containing compound metabolic process GO:0072521 155 0.018
ribose phosphate metabolic process GO:0019693 145 0.018
morphogenesis of embryonic epithelium GO:0016331 94 0.018
developmental programmed cell death GO:0010623 138 0.018
Fly
single organism cellular localization GO:1902580 180 0.018
protein modification process GO:0036211 438 0.018
malpighian tubule development GO:0072002 64 0.018
nephron development GO:0072006 3 0.018
homeostatic process GO:0042592 199 0.018
organonitrogen compound biosynthetic process GO:1901566 117 0.018
dorsal ventral pattern formation GO:0009953 133 0.018
salivary gland development GO:0007431 162 0.018
protein transport GO:0015031 155 0.018
chaeta development GO:0022416 97 0.018
organic cyclic compound catabolic process GO:1901361 168 0.017
regulation of growth GO:0040008 233 0.017
photoreceptor cell differentiation GO:0046530 170 0.017
immune response GO:0006955 246 0.017
mitotic nuclear division GO:0007067 213 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.017
Fly
proteolysis GO:0006508 192 0.017
cardiovascular system development GO:0072358 82 0.017
anatomical structure homeostasis GO:0060249 97 0.017
histolysis GO:0007559 102 0.017
leg disc morphogenesis GO:0007478 80 0.017
phosphorylation GO:0016310 294 0.017
heterocycle catabolic process GO:0046700 166 0.017
organic substance catabolic process GO:1901575 308 0.017
male mating behavior GO:0060179 70 0.017
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.017
imaginal disc pattern formation GO:0007447 91 0.017
cellular protein localization GO:0034613 160 0.017
positive regulation of phosphorus metabolic process GO:0010562 139 0.016
developmental maturation GO:0021700 172 0.016
eye photoreceptor cell differentiation GO:0001754 145 0.016
response to bacterium GO:0009617 198 0.016
immune system process GO:0002376 347 0.016
courtship behavior GO:0007619 68 0.016
salt aversion GO:0035199 3 0.016
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.016
positive regulation of signaling GO:0023056 243 0.016
steroid catabolic process GO:0006706 1 0.016
response to organophosphorus GO:0046683 2 0.016
cell migration GO:0016477 238 0.016
nucleotide biosynthetic process GO:0009165 34 0.016
actin filament organization GO:0007015 126 0.016
organic acid metabolic process GO:0006082 103 0.016
regulation of developmental growth GO:0048638 174 0.016
androgen metabolic process GO:0008209 1 0.015
multicellular organismal reproductive behavior GO:0033057 110 0.015
negative regulation of cell differentiation GO:0045596 143 0.015
negative regulation of transcription dna templated GO:0045892 237 0.015
Fly
embryonic development via the syncytial blastoderm GO:0001700 148 0.015
tube morphogenesis GO:0035239 191 0.015
multi organism reproductive behavior GO:0044705 121 0.015
response to starvation GO:0042594 97 0.015
cyclic nucleotide biosynthetic process GO:0009190 25 0.015
wing disc pattern formation GO:0035222 66 0.015
neuron projection guidance GO:0097485 241 0.015
negative regulation of nucleic acid templated transcription GO:1903507 240 0.015
Fly
positive regulation of molecular function GO:0044093 136 0.015
cellular response to oxygen containing compound GO:1901701 79 0.015
telencephalon development GO:0021537 2 0.015
oxoacid metabolic process GO:0043436 103 0.015
actin filament based process GO:0030029 220 0.015
chemosensory behavior GO:0007635 106 0.015
autophagic cell death GO:0048102 83 0.015
cellular ketone metabolic process GO:0042180 24 0.015
camp biosynthetic process GO:0006171 17 0.015
axis specification GO:0009798 167 0.014
columnar cuboidal epithelial cell development GO:0002066 249 0.014
negative regulation of gene expression GO:0010629 387 0.014
Fly
response to organic cyclic compound GO:0014070 89 0.014
ras protein signal transduction GO:0007265 88 0.014
sensory perception of smell GO:0007608 80 0.014
anterior posterior axis specification GO:0009948 109 0.014
defense response to bacterium GO:0042742 178 0.014
transmembrane transport GO:0055085 139 0.014
retina development in camera type eye GO:0060041 4 0.014
endomembrane system organization GO:0010256 119 0.014
cellular response to carbohydrate stimulus GO:0071322 4 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
regulation of cell differentiation GO:0045595 302 0.014
Fly
cell recognition GO:0008037 102 0.014
establishment of localization in cell GO:0051649 402 0.014
carboxylic acid metabolic process GO:0019752 92 0.014
cellular amino acid metabolic process GO:0006520 61 0.014
defense response to other organism GO:0098542 225 0.014
digestive tract development GO:0048565 149 0.014
cyclic purine nucleotide metabolic process GO:0052652 25 0.014
amine metabolic process GO:0009308 12 0.014
chemotaxis GO:0006935 249 0.014
xenobiotic catabolic process GO:0042178 1 0.014
somatic muscle development GO:0007525 66 0.013
aromatic compound catabolic process GO:0019439 166 0.013
cognition GO:0050890 141 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
regulation of epithelial cell differentiation GO:0030856 4 0.013
programmed cell death GO:0012501 257 0.013
Fly
regulation of cell cycle process GO:0010564 181 0.013
aggressive behavior GO:0002118 63 0.013
salivary gland histolysis GO:0035070 88 0.013
digestive system development GO:0055123 149 0.013
hindbrain development GO:0030902 2 0.013
regulation of protein metabolic process GO:0051246 256 0.013
olfactory behavior GO:0042048 97 0.013
positive regulation of cell migration GO:0030335 2 0.013
regulation of nucleotide metabolic process GO:0006140 62 0.013
establishment or maintenance of cell polarity GO:0007163 167 0.013
regulation of organelle organization GO:0033043 196 0.013
negative regulation of nervous system development GO:0051961 92 0.013
spinal cord development GO:0021510 1 0.013
regulation of response to stress GO:0080134 200 0.013
rhythmic behavior GO:0007622 76 0.013
synaptic transmission GO:0007268 288 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
carbohydrate derivative biosynthetic process GO:1901137 85 0.012
response to radiation GO:0009314 155 0.012
regulation of synapse structure and activity GO:0050803 128 0.012
mesenchymal cell differentiation GO:0048762 1 0.012
axon guidance GO:0007411 233 0.012
regulation of cell cycle GO:0051726 291 0.012
defense response to gram negative bacterium GO:0050829 94 0.012
meiotic cell cycle GO:0051321 171 0.012
limb development GO:0060173 1 0.012
response to nitrogen compound GO:1901698 90 0.012
innate immune response GO:0045087 144 0.012
response to ethanol GO:0045471 59 0.012
chromosome organization GO:0051276 360 0.012
sensory perception of salty taste GO:0050914 3 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
response to nutrient levels GO:0031667 114 0.012
epithelial cell development GO:0002064 274 0.012
purine ribonucleotide biosynthetic process GO:0009152 28 0.012
axon development GO:0061564 297 0.012
regulation of cellular protein metabolic process GO:0032268 243 0.012
regulation of innate immune response GO:0045088 71 0.012
epithelial cell differentiation GO:0030855 322 0.012
tripartite regional subdivision GO:0007351 103 0.012
salivary gland cell autophagic cell death GO:0035071 83 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
g protein coupled receptor signaling pathway GO:0007186 136 0.012
digestive tract morphogenesis GO:0048546 127 0.012
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.012
nephron epithelium development GO:0072009 3 0.012
cellular response to organic substance GO:0071310 132 0.012
muscle structure development GO:0061061 224 0.012
regulation of neurogenesis GO:0050767 158 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.012
hindgut development GO:0061525 58 0.011
connective tissue development GO:0061448 3 0.011
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.011
mesenchymal cell development GO:0014031 1 0.011
epithelial tube morphogenesis GO:0060562 88 0.011
regulation of immune response GO:0050776 118 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
macromolecule catabolic process GO:0009057 161 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
negative regulation of cell death GO:0060548 81 0.011
regulation of cell substrate adhesion GO:0010810 2 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.011
Fly
purine nucleoside metabolic process GO:0042278 127 0.011
positive regulation of catabolic process GO:0009896 105 0.011
wing disc dorsal ventral pattern formation GO:0048190 47 0.011
epithelial cell migration open tracheal system GO:0007427 32 0.011
benzene containing compound metabolic process GO:0042537 3 0.011
embryonic axis specification GO:0000578 107 0.011
positive regulation of nucleotide metabolic process GO:0045981 55 0.011
meiotic nuclear division GO:0007126 151 0.011
cellular homeostasis GO:0019725 80 0.011
synapse organization GO:0050808 196 0.011
regulation of catabolic process GO:0009894 170 0.011
ameboidal type cell migration GO:0001667 151 0.011
positive regulation of cell motility GO:2000147 3 0.011
purine ribonucleoside metabolic process GO:0046128 127 0.011
cell cycle phase transition GO:0044770 140 0.011
sensory perception of pain GO:0019233 4 0.011
gastrulation GO:0007369 70 0.011
regulation of catalytic activity GO:0050790 185 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
organophosphate biosynthetic process GO:0090407 46 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
regulation of purine nucleotide metabolic process GO:1900542 62 0.011
macromolecular complex assembly GO:0065003 256 0.010
cell division GO:0051301 248 0.010
hindgut morphogenesis GO:0007442 58 0.010
positive regulation of developmental growth GO:0048639 62 0.010
response to wounding GO:0009611 94 0.010
response to monosaccharide GO:0034284 4 0.010
regulation of immune system process GO:0002682 176 0.010
brain development GO:0007420 120 0.010
Fly
renal tubule development GO:0061326 64 0.010
response to extracellular stimulus GO:0009991 116 0.010
compound eye photoreceptor cell differentiation GO:0001751 140 0.010
chromatin organization GO:0006325 207 0.010
hematopoietic progenitor cell differentiation GO:0002244 1 0.010
secretion by cell GO:0032940 101 0.010
cell maturation GO:0048469 144 0.010
neuron fate commitment GO:0048663 50 0.010
regulation of programmed cell death GO:0043067 152 0.010
Fly
estrogen metabolic process GO:0008210 1 0.010
stem cell differentiation GO:0048863 117 0.010
protein complex assembly GO:0006461 200 0.010
hormone catabolic process GO:0042447 3 0.010

Scr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.053
musculoskeletal system disease DOID:17 0 0.016
connective tissue disease DOID:65 0 0.014
nervous system disease DOID:863 0 0.013
cardiovascular system disease DOID:1287 0 0.011