Drosophila melanogaster

14 known processes

decay (Dmel_CG14902)

death executioner caspase related to Apopain/Yama

(Aliases: caspase 3,CG14902,Casp3,DECAY,Decay,CC3,Caspase-3,Dmel\CG14902,Cas3,Drosophila executioner caspase related to Apopain/Yama,caspase-3)

decay biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spermatogenesis GO:0007283 200 0.349
Fly
response to high light intensity GO:0009644 1 0.193
multi multicellular organism process GO:0044706 123 0.128
spermatid development GO:0007286 98 0.094
Fly
wing disc morphogenesis GO:0007472 344 0.071
spermatid differentiation GO:0048515 114 0.068
Fly
positive regulation of signal transduction GO:0009967 223 0.061
Fly
synapse assembly GO:0007416 143 0.058
cellular response to light intensity GO:0071484 1 0.053
vesicle mediated transport GO:0016192 381 0.053
neurological system process GO:0050877 358 0.048
positive regulation of signaling GO:0023056 243 0.047
Fly
cell death GO:0008219 279 0.046
imaginal disc derived wing morphogenesis GO:0007476 337 0.046
response to temperature stimulus GO:0009266 106 0.046
Rat
aggressive behavior GO:0002118 63 0.046
learning or memory GO:0007611 141 0.045
cell motility GO:0048870 251 0.045
sensory perception of sound GO:0007605 56 0.044
post embryonic appendage morphogenesis GO:0035120 385 0.044
epithelial cell differentiation GO:0030855 322 0.044
response to abiotic stimulus GO:0009628 341 0.043
Rat
positive regulation of cell communication GO:0010647 250 0.043
Fly
epithelial cell development GO:0002064 274 0.042
columnar cuboidal epithelial cell development GO:0002066 249 0.042
intracellular signal transduction GO:0035556 300 0.040
imaginal disc derived appendage development GO:0048737 399 0.040
tissue morphogenesis GO:0048729 297 0.040
imaginal disc derived appendage morphogenesis GO:0035114 395 0.039
regulation of intracellular signal transduction GO:1902531 236 0.038
response to radiation GO:0009314 155 0.038
Rat
inter male aggressive behavior GO:0002121 60 0.036
synaptic transmission GO:0007268 288 0.035
regulation of localization GO:0032879 275 0.035
negative regulation of gene expression GO:0010629 387 0.034
intracellular transport GO:0046907 228 0.033
immune response GO:0006955 246 0.033
Fly
morphogenesis of an epithelium GO:0002009 276 0.033
response to organic substance GO:0010033 284 0.032
Rat
appendage morphogenesis GO:0035107 397 0.032
cognition GO:0050890 141 0.032
synapse organization GO:0050808 196 0.031
positive regulation of response to stimulus GO:0048584 323 0.031
Fly
eye development GO:0001654 323 0.031
Rat Fly
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.031
multicellular organismal reproductive behavior GO:0033057 110 0.031
cellularization GO:0007349 90 0.030
Fly
appendage development GO:0048736 401 0.030
sensory organ morphogenesis GO:0090596 260 0.029
Rat Fly
positive regulation of intracellular signal transduction GO:1902533 116 0.029
regulation of multi organism process GO:0043900 131 0.028
regulation of reproductive process GO:2000241 54 0.028
death GO:0016265 284 0.027
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.027
localization of cell GO:0051674 257 0.027
embryonic development via the syncytial blastoderm GO:0001700 148 0.026
Fly
ovarian follicle cell development GO:0030707 248 0.026
regionalization GO:0003002 416 0.026
cell cell junction assembly GO:0007043 38 0.026
regulation of organelle organization GO:0033043 196 0.026
chaeta development GO:0022416 97 0.025
protein modification process GO:0036211 438 0.025
regulation of cellular component biogenesis GO:0044087 201 0.024
cell recognition GO:0008037 102 0.024
body morphogenesis GO:0010171 2 0.024
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.024
respiratory system development GO:0060541 213 0.024
multicellular organismal aging GO:0010259 140 0.024
Fly
negative regulation of signal transduction GO:0009968 206 0.024
lateral inhibition GO:0046331 206 0.023
embryonic morphogenesis GO:0048598 206 0.022
Fly
sensory perception GO:0007600 196 0.022
cell maturation GO:0048469 144 0.022
Fly
endocytosis GO:0006897 310 0.022
cellular protein modification process GO:0006464 438 0.021
catabolic process GO:0009056 409 0.021
Fly
regulation of anatomical structure morphogenesis GO:0022603 242 0.021
Rat Fly
actin cytoskeleton organization GO:0030036 206 0.021
organic substance catabolic process GO:1901575 308 0.021
cellular nitrogen compound catabolic process GO:0044270 165 0.021
regulation of behavior GO:0050795 75 0.020
negative regulation of response to stimulus GO:0048585 258 0.020
regulation of oviposition GO:0046662 14 0.020
ribose phosphate metabolic process GO:0019693 145 0.020
cell migration GO:0016477 238 0.020
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.020
protein localization GO:0008104 284 0.020
embryo development ending in birth or egg hatching GO:0009792 152 0.020
Fly
developmental maturation GO:0021700 172 0.020
Fly
actin filament based process GO:0030029 220 0.020
positive regulation of molecular function GO:0044093 136 0.019
Fly
response to light stimulus GO:0009416 124 0.019
multi organism behavior GO:0051705 175 0.019
tube development GO:0035295 244 0.018
developmental pigmentation GO:0048066 68 0.018
negative regulation of cell communication GO:0010648 223 0.018
sensory perception of mechanical stimulus GO:0050954 72 0.018
cytoplasmic transport GO:0016482 130 0.018
regulation of cell cycle GO:0051726 291 0.018
transcription from rna polymerase ii promoter GO:0006366 368 0.018
compound eye morphogenesis GO:0001745 249 0.018
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.018
organonitrogen compound metabolic process GO:1901564 318 0.017
cell junction assembly GO:0034329 42 0.017
immune system process GO:0002376 347 0.017
Fly
mating GO:0007618 120 0.017
single organism behavior GO:0044708 391 0.017
morphogenesis of embryonic epithelium GO:0016331 94 0.016
eye morphogenesis GO:0048592 260 0.016
Rat Fly
cell proliferation GO:0008283 299 0.016
Fly
reproductive behavior GO:0019098 122 0.016
chemosensory behavior GO:0007635 106 0.016
negative regulation of signaling GO:0023057 219 0.016
organic acid metabolic process GO:0006082 103 0.016
programmed cell death GO:0012501 257 0.016
molting cycle chitin based cuticle GO:0007591 56 0.016
regulation of catabolic process GO:0009894 170 0.016
Fly
dorsal closure GO:0007391 79 0.016
regulation of cytoskeleton organization GO:0051493 89 0.016
cuticle development GO:0042335 86 0.016
actin filament organization GO:0007015 126 0.015
organophosphate metabolic process GO:0019637 195 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.015
apoptotic process GO:0006915 159 0.015
embryonic pattern specification GO:0009880 174 0.015
phosphorylation GO:0016310 294 0.015
male courtship behavior GO:0008049 63 0.015
learning GO:0007612 75 0.015
establishment of localization in cell GO:0051649 402 0.015
positive regulation of cellular component organization GO:0051130 156 0.015
positive regulation of gene expression GO:0010628 290 0.015
regulation of cellular localization GO:0060341 136 0.015
nucleoside triphosphate metabolic process GO:0009141 120 0.014
phagocytosis GO:0006909 215 0.014
cell junction organization GO:0034330 57 0.014
activation of innate immune response GO:0002218 4 0.014
regulation of cell shape GO:0008360 113 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.014
cellular catabolic process GO:0044248 372 0.014
Fly
intracellular protein transport GO:0006886 104 0.014
endomembrane system organization GO:0010256 119 0.014
limb development GO:0060173 1 0.014
positive regulation of cellular protein metabolic process GO:0032270 118 0.013
Fly
negative regulation of biosynthetic process GO:0009890 277 0.013
purine ribonucleoside metabolic process GO:0046128 127 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.013
rho protein signal transduction GO:0007266 14 0.013
response to biotic stimulus GO:0009607 294 0.013
ribonucleoside triphosphate catabolic process GO:0009203 108 0.013
organelle localization GO:0051640 148 0.013
response to oxygen containing compound GO:1901700 200 0.013
Rat
establishment or maintenance of cell polarity GO:0007163 167 0.013
proteolysis GO:0006508 192 0.013
protein transport GO:0015031 155 0.013
single organism intracellular transport GO:1902582 207 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
open tracheal system development GO:0007424 204 0.013
organic substance transport GO:0071702 257 0.013
neuron recognition GO:0008038 101 0.013
negative regulation of transcription dna templated GO:0045892 237 0.013
dorsal appendage formation GO:0046843 47 0.013
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.012
connective tissue development GO:0061448 3 0.012
insemination GO:0007320 22 0.012
cell projection assembly GO:0030031 94 0.012
aromatic compound catabolic process GO:0019439 166 0.012
segmentation GO:0035282 207 0.012
cellular protein localization GO:0034613 160 0.012
detection of stimulus GO:0051606 156 0.012
chemical homeostasis GO:0048878 92 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
positive regulation of organelle organization GO:0010638 65 0.012
establishment of protein localization GO:0045184 163 0.012
forebrain development GO:0030900 2 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
positive regulation of biosynthetic process GO:0009891 316 0.012
larval development GO:0002164 104 0.012
regulation of cellular component size GO:0032535 98 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.012
pigment biosynthetic process GO:0046148 36 0.012
positive regulation of rna metabolic process GO:0051254 271 0.012
cell cell junction organization GO:0045216 55 0.012
positive regulation of transport GO:0051050 92 0.012
purine containing compound catabolic process GO:0072523 112 0.012
small molecule metabolic process GO:0044281 305 0.012
cilium assembly GO:0042384 38 0.012
membrane budding GO:0006900 4 0.012
male gamete generation GO:0048232 201 0.012
Fly
regulation of immune system process GO:0002682 176 0.011
locomotory behavior GO:0007626 176 0.011
axis specification GO:0009798 167 0.011
positive regulation of hydrolase activity GO:0051345 78 0.011
Fly
carboxylic acid metabolic process GO:0019752 92 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
regulation of protein modification process GO:0031399 112 0.011
apical junction assembly GO:0043297 32 0.011
negative regulation of cellular metabolic process GO:0031324 382 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
cell cycle phase transition GO:0044770 140 0.011
cellular response to abiotic stimulus GO:0071214 58 0.011
oocyte construction GO:0007308 112 0.011
purine nucleoside triphosphate catabolic process GO:0009146 108 0.011
positive regulation of catabolic process GO:0009896 105 0.011
positive regulation of transcription dna templated GO:0045893 266 0.011
positive regulation of cytoskeleton organization GO:0051495 21 0.011
negative regulation of rna metabolic process GO:0051253 251 0.011
reproductive system development GO:0061458 74 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
olfactory behavior GO:0042048 97 0.011
taxis GO:0042330 304 0.011
regulation of transport GO:0051049 181 0.011
negative regulation of cellular biosynthetic process GO:0031327 277 0.011
positive regulation of rna biosynthetic process GO:1902680 266 0.011
positive regulation of exocytosis GO:0045921 4 0.011
golgi organization GO:0007030 66 0.010
immune effector process GO:0002252 98 0.010
negative regulation of nucleic acid templated transcription GO:1903507 240 0.010
cellular ketone metabolic process GO:0042180 24 0.010
axonogenesis GO:0007409 290 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
Fly
regulation of cell differentiation GO:0045595 302 0.010
Rat Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.010
glycosyl compound catabolic process GO:1901658 112 0.010
neuron projection guidance GO:0097485 241 0.010
regulation of gtpase activity GO:0043087 44 0.010
cellular macromolecule catabolic process GO:0044265 136 0.010

decay disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
sensory system disease DOID:0050155 0 0.016
nervous system disease DOID:863 0 0.016
musculoskeletal system disease DOID:17 0 0.013