Drosophila melanogaster

39 known processes

Pep (Dmel_CG6143)

Protein on ecdysone puffs

(Aliases: X4/PEP,PEP/X4,pep,PEP,p100,Dmel\CG6143,CG6143)

Pep biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic nuclear division GO:0007067 213 0.506
nuclear division GO:0000280 332 0.364
regulation of mrna splicing via spliceosome GO:0048024 64 0.363
negative regulation of rna metabolic process GO:0051253 251 0.351
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.285
regulation of cell cycle process GO:0010564 181 0.278
rna processing GO:0006396 147 0.273
negative regulation of gene expression GO:0010629 387 0.245
negative regulation of cellular metabolic process GO:0031324 382 0.218
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.201
regulation of mitosis GO:0007088 56 0.173
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.169
mrna splicing via spliceosome GO:0000398 73 0.163
regulation of mrna processing GO:0050684 71 0.152
negative regulation of transcription dna templated GO:0045892 237 0.149
mrna metabolic process GO:0016071 124 0.139
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.139
positive regulation of transcription dna templated GO:0045893 266 0.132
negative regulation of rna biosynthetic process GO:1902679 240 0.125
negative regulation of biosynthetic process GO:0009890 277 0.123
mitotic spindle organization GO:0007052 220 0.122
positive regulation of macromolecule metabolic process GO:0010604 405 0.121
positive regulation of rna metabolic process GO:0051254 271 0.116
response to abiotic stimulus GO:0009628 341 0.112
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.105
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.098
intracellular signal transduction GO:0035556 300 0.097
Fly
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.093
regulation of localization GO:0032879 275 0.092
imaginal disc derived appendage development GO:0048737 399 0.090
translation GO:0006412 69 0.085
multi organism behavior GO:0051705 175 0.083
regulation of cell cycle GO:0051726 291 0.083
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.083
regulation of mitotic cell cycle GO:0007346 190 0.082
regulation of cellular component biogenesis GO:0044087 201 0.079
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.078
stem cell differentiation GO:0048863 117 0.078
endocytosis GO:0006897 310 0.077
positive regulation of biosynthetic process GO:0009891 316 0.077
regulation of mrna metabolic process GO:1903311 72 0.077
organonitrogen compound metabolic process GO:1901564 318 0.075
vesicle mediated transport GO:0016192 381 0.074
regulation of cellular protein metabolic process GO:0032268 243 0.070
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.070
negative regulation of nucleic acid templated transcription GO:1903507 240 0.069
single organism behavior GO:0044708 391 0.068
detection of stimulus GO:0051606 156 0.067
catabolic process GO:0009056 409 0.066
phosphorylation GO:0016310 294 0.066
organic substance transport GO:0071702 257 0.065
negative regulation of developmental process GO:0051093 201 0.065
alternative mrna splicing via spliceosome GO:0000380 60 0.064
stem cell development GO:0048864 79 0.064
organic substance catabolic process GO:1901575 308 0.063
positive regulation of cellular biosynthetic process GO:0031328 316 0.062
death GO:0016265 284 0.062
single organism catabolic process GO:0044712 228 0.060
regulation of organelle organization GO:0033043 196 0.058
positive regulation of gene expression GO:0010628 290 0.058
body morphogenesis GO:0010171 2 0.058
chromosome organization GO:0051276 360 0.056
regulation of protein metabolic process GO:0051246 256 0.056
negative regulation of cellular biosynthetic process GO:0031327 277 0.055
mitotic sister chromatid segregation GO:0000070 87 0.055
positive regulation of nucleic acid templated transcription GO:1903508 266 0.053
response to other organism GO:0051707 293 0.051
homeostatic process GO:0042592 199 0.050
negative regulation of multicellular organismal process GO:0051241 142 0.049
regulation of phosphorylation GO:0042325 147 0.049
cellular protein modification process GO:0006464 438 0.048
stem cell maintenance GO:0019827 67 0.048
spindle organization GO:0007051 253 0.048
regulation of multi organism process GO:0043900 131 0.047
positive regulation of cellular component biogenesis GO:0044089 80 0.046
protein modification process GO:0036211 438 0.046
regulation of cell division GO:0051302 72 0.046
response to organic substance GO:0010033 284 0.046
cell division GO:0051301 248 0.045
cellular catabolic process GO:0044248 372 0.045
posttranscriptional regulation of gene expression GO:0010608 145 0.043
mrna processing GO:0006397 104 0.043
positive regulation of rna biosynthetic process GO:1902680 266 0.041
aging GO:0007568 143 0.041
small molecule metabolic process GO:0044281 305 0.041
organelle fission GO:0048285 340 0.040
proteolysis GO:0006508 192 0.039
rna splicing GO:0008380 83 0.038
multicellular organismal reproductive behavior GO:0033057 110 0.036
determination of adult lifespan GO:0008340 137 0.036
regulation of phosphorus metabolic process GO:0051174 210 0.036
regulation of phosphatase activity GO:0010921 3 0.035
negative regulation of protein metabolic process GO:0051248 85 0.034
response to bacterium GO:0009617 198 0.034
negative regulation of cellular protein metabolic process GO:0032269 85 0.034
sister chromatid segregation GO:0000819 92 0.033
oxoacid metabolic process GO:0043436 103 0.033
transcription from rna polymerase ii promoter GO:0006366 368 0.032
positive regulation of cellular component organization GO:0051130 156 0.032
regulation of rna splicing GO:0043484 69 0.031
defense response to gram negative bacterium GO:0050829 94 0.031
regulation of gene expression epigenetic GO:0040029 128 0.030
regulation of nuclear division GO:0051783 58 0.029
morphogenesis of an epithelium GO:0002009 276 0.029
regulation of response to stress GO:0080134 200 0.029
positive regulation of phosphorus metabolic process GO:0010562 139 0.029
positive regulation of intracellular signal transduction GO:1902533 116 0.028
Fly
response to external biotic stimulus GO:0043207 293 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.027
carbohydrate derivative metabolic process GO:1901135 217 0.026
protein phosphorylation GO:0006468 169 0.026
nitrogen compound transport GO:0071705 85 0.026
negative regulation of cell cycle process GO:0010948 109 0.026
nucleobase containing small molecule metabolic process GO:0055086 174 0.026
intracellular transport GO:0046907 228 0.026
establishment of localization in cell GO:0051649 402 0.025
oocyte development GO:0048599 124 0.025
peptide metabolic process GO:0006518 80 0.025
cell proliferation GO:0008283 299 0.025
purine nucleoside catabolic process GO:0006152 112 0.025
regulation of mitotic cell cycle phase transition GO:1901990 130 0.025
cellular response to chemical stimulus GO:0070887 199 0.024
response to radiation GO:0009314 155 0.024
dendrite development GO:0016358 204 0.024
nucleotide metabolic process GO:0009117 161 0.024
positive regulation of response to stimulus GO:0048584 323 0.024
Fly
heterochromatin organization GO:0070828 25 0.024
regulation of phosphate metabolic process GO:0019220 210 0.023
compound eye development GO:0048749 307 0.023
cellular response to organic substance GO:0071310 132 0.023
rna splicing via transesterification reactions GO:0000375 73 0.022
posttranscriptional gene silencing by rna GO:0035194 45 0.022
gland development GO:0048732 191 0.022
response to light stimulus GO:0009416 124 0.022
cell death GO:0008219 279 0.022
production of molecular mediator of immune response GO:0002440 46 0.021
exocrine system development GO:0035272 162 0.021
organic cyclic compound catabolic process GO:1901361 168 0.021
regulation of catalytic activity GO:0050790 185 0.021
macromolecule catabolic process GO:0009057 161 0.021
programmed cell death GO:0012501 257 0.021
embryo development ending in birth or egg hatching GO:0009792 152 0.021
regulation of synapse structure and activity GO:0050803 128 0.020
chromosome segregation GO:0007059 157 0.020
ribonucleotide metabolic process GO:0009259 145 0.020
imaginal disc derived appendage morphogenesis GO:0035114 395 0.020
carbohydrate derivative catabolic process GO:1901136 118 0.020
regulation of protein modification process GO:0031399 112 0.020
multi multicellular organism process GO:0044706 123 0.020
open tracheal system development GO:0007424 204 0.020
purine nucleotide metabolic process GO:0006163 146 0.020
regulation of translation GO:0006417 56 0.019
phagocytosis GO:0006909 215 0.019
multicellular organismal aging GO:0010259 140 0.019
signal transduction by phosphorylation GO:0023014 107 0.019
germ line stem cell maintenance GO:0030718 50 0.019
eggshell formation GO:0030703 105 0.019
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.018
regulation of cellular localization GO:0060341 136 0.018
sensory organ morphogenesis GO:0090596 260 0.018
actin cytoskeleton organization GO:0030036 206 0.018
organonitrogen compound catabolic process GO:1901565 128 0.018
retina development in camera type eye GO:0060041 4 0.018
regulation of multicellular organismal development GO:2000026 414 0.018
organophosphate metabolic process GO:0019637 195 0.017
gland morphogenesis GO:0022612 145 0.017
negative regulation of neurotransmitter secretion GO:0046929 2 0.017
regulation of cytoskeleton organization GO:0051493 89 0.017
positive regulation of molecular function GO:0044093 136 0.016
organic acid metabolic process GO:0006082 103 0.016
regulation of immune response GO:0050776 118 0.016
glycosyl compound metabolic process GO:1901657 127 0.016
salivary gland development GO:0007431 162 0.016
purine nucleoside triphosphate metabolic process GO:0009144 119 0.016
lipid localization GO:0010876 54 0.016
negative regulation of mitotic sister chromatid segregation GO:0033048 13 0.015
positive regulation of signaling GO:0023056 243 0.015
Fly
rna interference GO:0016246 27 0.015
aromatic compound catabolic process GO:0019439 166 0.015
positive regulation of cellular protein metabolic process GO:0032270 118 0.015
mrna 3 end processing GO:0031124 28 0.015
appendage development GO:0048736 401 0.015
regulation of developmental growth GO:0048638 174 0.015
cellular response to molecule of bacterial origin GO:0071219 3 0.015
tissue morphogenesis GO:0048729 297 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.014
immune system process GO:0002376 347 0.014
regulation of cell shape GO:0008360 113 0.014
regulation of lipid transport GO:0032368 3 0.014
mitotic cell cycle phase transition GO:0044772 138 0.014
nuclear pore organization GO:0006999 1 0.014
negative regulation of translation GO:0017148 28 0.014
eye development GO:0001654 323 0.014
posttranscriptional gene silencing GO:0016441 46 0.013
meiotic nuclear division GO:0007126 151 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
regulation of dna metabolic process GO:0051052 34 0.013
negative regulation of cellular component organization GO:0051129 108 0.013
regionalization GO:0003002 416 0.013
microtubule anchoring GO:0034453 11 0.013
eye morphogenesis GO:0048592 260 0.013
response to biotic stimulus GO:0009607 294 0.013
respiratory system development GO:0060541 213 0.013
establishment of rna localization GO:0051236 47 0.013
rna 3 end processing GO:0031123 45 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.012
regulation of cellular response to stress GO:0080135 89 0.012
centrosome organization GO:0051297 163 0.012
response to temperature stimulus GO:0009266 106 0.012
multi organism reproductive behavior GO:0044705 121 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
regulation of chromosome organization GO:0033044 64 0.012
organophosphate catabolic process GO:0046434 112 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
g1 s transition of mitotic cell cycle GO:0000082 31 0.012
cellular macromolecule catabolic process GO:0044265 136 0.011
regulation of chromatin modification GO:1903308 28 0.011
mitotic spindle checkpoint GO:0071174 11 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
translational initiation GO:0006413 11 0.011
cell cycle phase transition GO:0044770 140 0.011
post embryonic appendage morphogenesis GO:0035120 385 0.011
negative regulation of protein phosphorylation GO:0001933 17 0.011
heterocycle catabolic process GO:0046700 166 0.011
protein localization GO:0008104 284 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
regulation of intracellular signal transduction GO:1902531 236 0.011
Fly
regulation of molecular function GO:0065009 217 0.011
taxis GO:0042330 304 0.011
single organism biosynthetic process GO:0044711 206 0.011
nucleoside phosphate catabolic process GO:1901292 110 0.011
intermediate filament cytoskeleton organization GO:0045104 1 0.011
establishment or maintenance of cell polarity GO:0007163 167 0.011
negative regulation of cell division GO:0051782 17 0.011
detection of abiotic stimulus GO:0009582 66 0.011
embryonic axis specification GO:0000578 107 0.010
purine containing compound metabolic process GO:0072521 155 0.010
camera type eye development GO:0043010 4 0.010
tube morphogenesis GO:0035239 191 0.010
regulation of hemocyte proliferation GO:0035206 37 0.010
positive regulation of cell communication GO:0010647 250 0.010
Fly
mitotic spindle assembly checkpoint GO:0007094 11 0.010
cell cycle checkpoint GO:0000075 95 0.010
morphogenesis of follicular epithelium GO:0016333 36 0.010
regulation of immune system process GO:0002682 176 0.010
purine nucleoside triphosphate catabolic process GO:0009146 108 0.010
regulation of anatomical structure morphogenesis GO:0022603 242 0.010
negative regulation of mitotic cell cycle GO:0045930 109 0.010
response to oxygen containing compound GO:1901700 200 0.010

Pep disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.019
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014