Drosophila melanogaster

64 known processes

Past1 (Dmel_CG6148)

Putative Achaete Scute Target 1

(Aliases: PAST-1,CG6148,PAST,Ehd,dEHD,Dmel\CG6148,Past-1)

Past1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spermatid differentiation GO:0048515 114 0.999
sperm individualization GO:0007291 48 0.958
spermatogenesis GO:0007283 200 0.944
male gamete generation GO:0048232 201 0.870
spermatid development GO:0007286 98 0.860
cellularization GO:0007349 90 0.735
establishment of localization in cell GO:0051649 402 0.326
Human Mouse Worm
regulation of localization GO:0032879 275 0.220
Mouse
ion transmembrane transport GO:0034220 122 0.220
endomembrane system organization GO:0010256 119 0.209
Mouse
single organism membrane organization GO:0044802 93 0.191
Mouse
proteolysis GO:0006508 192 0.185
cellular catabolic process GO:0044248 372 0.185
Worm
cellular macromolecule localization GO:0070727 220 0.180
Human Mouse
regulation of transport GO:0051049 181 0.173
Mouse
single organism cellular localization GO:1902580 180 0.171
Mouse
metal ion transport GO:0030001 74 0.170
actin cytoskeleton organization GO:0030036 206 0.166
protein transport GO:0015031 155 0.158
Human Mouse
endocytosis GO:0006897 310 0.155
oocyte development GO:0048599 124 0.140
regulation of cellular component biogenesis GO:0044087 201 0.132
pole plasm rna localization GO:0007316 52 0.126
organophosphate metabolic process GO:0019637 195 0.112
Worm
organic substance transport GO:0071702 257 0.106
Human Mouse
actin filament based process GO:0030029 220 0.104
oocyte construction GO:0007308 112 0.104
cellular macromolecular complex assembly GO:0034622 153 0.098
regulation of organelle organization GO:0033043 196 0.095
vesicle mediated transport GO:0016192 381 0.094
morphogenesis of an epithelium GO:0002009 276 0.090
protein localization GO:0008104 284 0.090
Human Mouse
catabolic process GO:0009056 409 0.088
Worm
pole plasm mrna localization GO:0019094 49 0.087
oocyte differentiation GO:0009994 145 0.087
ion transport GO:0006811 145 0.085
single organism intracellular transport GO:1902582 207 0.085
Human Mouse Worm
oocyte axis specification GO:0007309 108 0.084
autophagy GO:0006914 108 0.080
meiosis i GO:0007127 59 0.080
negative regulation of gene expression GO:0010629 387 0.079
embryonic axis specification GO:0000578 107 0.078
embryo development ending in birth or egg hatching GO:0009792 152 0.075
Worm
regulation of proteolysis GO:0030162 87 0.073
cellular macromolecule catabolic process GO:0044265 136 0.073
rna splicing GO:0008380 83 0.071
maternal determination of anterior posterior axis embryo GO:0008358 74 0.070
establishment or maintenance of cell polarity GO:0007163 167 0.070
pole plasm assembly GO:0007315 61 0.068
oocyte anterior posterior axis specification GO:0007314 72 0.065
meiotic cell cycle process GO:1903046 132 0.065
response to oxygen containing compound GO:1901700 200 0.065
regulation of cell cycle GO:0051726 291 0.063
cellular response to dna damage stimulus GO:0006974 223 0.063
membrane organization GO:0061024 112 0.062
Mouse
cellular protein localization GO:0034613 160 0.061
Human Mouse
dorsal appendage formation GO:0046843 47 0.060
cytoplasm organization GO:0007028 64 0.059
regulation of multicellular organismal development GO:2000026 414 0.059
regulation of cell development GO:0060284 215 0.059
developmental programmed cell death GO:0010623 138 0.057
intracellular transport GO:0046907 228 0.057
Human Mouse Worm
immune system process GO:0002376 347 0.056
phagocytosis GO:0006909 215 0.056
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.055
response to organic substance GO:0010033 284 0.054
developmental maturation GO:0021700 172 0.053
cytokinesis GO:0000910 90 0.052
histolysis GO:0007559 102 0.052
response to abiotic stimulus GO:0009628 341 0.051
segmentation GO:0035282 207 0.050
single organism biosynthetic process GO:0044711 206 0.050
protein catabolic process GO:0030163 101 0.049
centrosome organization GO:0051297 163 0.049
posttranscriptional regulation of gene expression GO:0010608 145 0.049
transmembrane transport GO:0055085 139 0.049
chromosome organization GO:0051276 360 0.048
actin filament organization GO:0007015 126 0.048
negative regulation of cellular metabolic process GO:0031324 382 0.048
lipid localization GO:0010876 54 0.048
Mouse
post embryonic appendage morphogenesis GO:0035120 385 0.047
exocrine system development GO:0035272 162 0.047
synapse assembly GO:0007416 143 0.046
locomotory behavior GO:0007626 176 0.046
regulation of cellular protein metabolic process GO:0032268 243 0.045
tissue death GO:0016271 102 0.045
cellular protein complex assembly GO:0043623 71 0.042
aging GO:0007568 143 0.042
eggshell chorion assembly GO:0007306 66 0.042
synaptic transmission GO:0007268 288 0.042
rna processing GO:0006396 147 0.042
gland morphogenesis GO:0022612 145 0.041
cellular lipid metabolic process GO:0044255 83 0.040
organelle fission GO:0048285 340 0.040
Worm
rna localization GO:0006403 115 0.040
positive regulation of cell migration GO:0030335 2 0.040
myotube differentiation GO:0014902 46 0.039
Mouse
purine containing compound metabolic process GO:0072521 155 0.039
Worm
germarium derived egg chamber formation GO:0007293 101 0.039
pole plasm oskar mrna localization GO:0045451 46 0.038
gene silencing GO:0016458 138 0.038
lipid modification GO:0030258 24 0.038
glycosyl compound metabolic process GO:1901657 127 0.037
Worm
embryonic development via the syncytial blastoderm GO:0001700 148 0.037
cell maturation GO:0048469 144 0.036
lipid metabolic process GO:0006629 121 0.036
cation transmembrane transport GO:0098655 88 0.036
activation of cysteine type endopeptidase activity GO:0097202 17 0.035
syncytium formation GO:0006949 43 0.035
Mouse
secretion GO:0046903 109 0.035
anterior posterior axis specification embryo GO:0008595 103 0.035
organic acid metabolic process GO:0006082 103 0.034
negative regulation of cellular protein metabolic process GO:0032269 85 0.034
protein complex assembly GO:0006461 200 0.034
Human
regulation of cell differentiation GO:0045595 302 0.034
Mouse
regulation of protein metabolic process GO:0051246 256 0.034
microtubule organizing center organization GO:0031023 168 0.034
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.034
salivary gland morphogenesis GO:0007435 145 0.034
regulation of intracellular transport GO:0032386 64 0.034
Mouse
regionalization GO:0003002 416 0.033
regulation of cellular localization GO:0060341 136 0.033
Mouse
establishment of protein localization GO:0045184 163 0.033
Human Mouse
cell recognition GO:0008037 102 0.033
macromolecular complex assembly GO:0065003 256 0.033
Human
intracellular protein transport GO:0006886 104 0.033
Human Mouse
regulation of mitotic cell cycle GO:0007346 190 0.033
cell death GO:0008219 279 0.033
Worm
tissue morphogenesis GO:0048729 297 0.032
negative regulation of cell cycle GO:0045786 116 0.031
forebrain development GO:0030900 2 0.031
positive regulation of exocytosis GO:0045921 4 0.031
mitotic nuclear division GO:0007067 213 0.031
adult behavior GO:0030534 137 0.030
cellular protein modification process GO:0006464 438 0.030
cell migration GO:0016477 238 0.030
epithelial cell development GO:0002064 274 0.029
centrosome duplication GO:0051298 121 0.029
nucleobase containing small molecule metabolic process GO:0055086 174 0.029
Worm
blastoderm segmentation GO:0007350 159 0.028
protein secretion GO:0009306 45 0.028
mitochondrion organization GO:0007005 65 0.028
microtubule polymerization or depolymerization GO:0031109 39 0.028
oxoacid metabolic process GO:0043436 103 0.027
meiotic nuclear division GO:0007126 151 0.027
Worm
axon development GO:0061564 297 0.027
wing disc morphogenesis GO:0007472 344 0.027
hemopoiesis GO:0030097 46 0.027
regulation of cytoskeleton organization GO:0051493 89 0.027
neuron recognition GO:0008038 101 0.026
cellular protein catabolic process GO:0044257 83 0.026
cell proliferation GO:0008283 299 0.026
chromatin silencing GO:0006342 76 0.026
cytoplasmic transport GO:0016482 130 0.026
single organism behavior GO:0044708 391 0.026
intracellular signal transduction GO:0035556 300 0.026
salivary gland development GO:0007431 162 0.025
body morphogenesis GO:0010171 2 0.025
anion transport GO:0006820 41 0.025
cellular homeostasis GO:0019725 80 0.025
homeostatic process GO:0042592 199 0.025
Mouse
tripartite regional subdivision GO:0007351 103 0.025
salivary gland cell autophagic cell death GO:0035071 83 0.025
positive regulation of cell differentiation GO:0045597 64 0.025
Mouse
death GO:0016265 284 0.024
Worm
anterior posterior axis specification GO:0009948 109 0.024
negative regulation of protein metabolic process GO:0051248 85 0.024
cation transport GO:0006812 110 0.024
protein maturation GO:0051604 71 0.024
transition metal ion transport GO:0000041 16 0.024
regulation of microtubule based process GO:0032886 49 0.024
nuclear division GO:0000280 332 0.024
Worm
myotube cell development GO:0014904 3 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.024
programmed cell death GO:0012501 257 0.024
organic substance catabolic process GO:1901575 308 0.024
Worm
sensory organ morphogenesis GO:0090596 260 0.023
cellular amino acid metabolic process GO:0006520 61 0.023
regulation of secretion by cell GO:1903530 39 0.023
ameboidal type cell migration GO:0001667 151 0.023
intracellular mrna localization GO:0008298 66 0.022
positive regulation of cell communication GO:0010647 250 0.022
respiratory system development GO:0060541 213 0.022
epithelial cell differentiation GO:0030855 322 0.022
embryonic pattern specification GO:0009880 174 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.022
cell adhesion GO:0007155 136 0.022
male meiosis i GO:0007141 9 0.022
regulation of synaptic transmission GO:0050804 69 0.022
regulation of nervous system development GO:0051960 248 0.022
heterochromatin organization GO:0070828 25 0.022
cell division GO:0051301 248 0.022
nucleus organization GO:0006997 45 0.021
negative regulation of gene expression epigenetic GO:0045814 77 0.021
iron ion transmembrane transport GO:0034755 4 0.021
female germ line cyst formation GO:0048135 42 0.021
asymmetric cell division GO:0008356 37 0.021
developmental growth GO:0048589 280 0.021
cellular component assembly involved in morphogenesis GO:0010927 151 0.021
microtubule depolymerization GO:0007019 25 0.021
signal release GO:0023061 49 0.020
carbohydrate derivative metabolic process GO:1901135 217 0.020
Worm
nucleoside metabolic process GO:0009116 127 0.020
Worm
positive regulation of signaling GO:0023056 243 0.020
spindle organization GO:0007051 253 0.020
protein complex biogenesis GO:0070271 201 0.020
Human
muscle cell differentiation GO:0042692 103 0.020
Mouse
localization of cell GO:0051674 257 0.020
negative regulation of cell communication GO:0010648 223 0.020
head development GO:0060322 135 0.019
anterior posterior pattern specification GO:0009952 136 0.019
regulation of oocyte development GO:0060281 27 0.019
skeletal muscle fiber development GO:0048741 3 0.019
chromosome segregation GO:0007059 157 0.019
regulation of translation GO:0006417 56 0.019
macromolecule catabolic process GO:0009057 161 0.019
response to lipopolysaccharide GO:0032496 4 0.019
regulation of molecular function GO:0065009 217 0.019
apoptotic process GO:0006915 159 0.018
ubiquitin dependent protein catabolic process GO:0006511 78 0.018
fertilization GO:0009566 26 0.018
regulation of gene silencing GO:0060968 63 0.018
regulation of gene expression epigenetic GO:0040029 128 0.018
immune system development GO:0002520 57 0.018
oocyte microtubule cytoskeleton organization GO:0016325 35 0.018
regulation of anatomical structure morphogenesis GO:0022603 242 0.018
Mouse
negative regulation of response to stimulus GO:0048585 258 0.018
growth GO:0040007 359 0.018
positive regulation of cell motility GO:2000147 3 0.018
protein polymerization GO:0051258 42 0.018
protein processing GO:0016485 68 0.018
organonitrogen compound metabolic process GO:1901564 318 0.018
Worm
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.018
response to alcohol GO:0097305 95 0.018
cellular response to molecule of bacterial origin GO:0071219 3 0.018
golgi organization GO:0007030 66 0.018
proteasomal protein catabolic process GO:0010498 59 0.017
biological adhesion GO:0022610 138 0.017
mitotic spindle organization GO:0007052 220 0.017
regulation of endopeptidase activity GO:0052548 36 0.017
regulation of embryonic pattern specification GO:1902875 27 0.017
muscle structure development GO:0061061 224 0.017
Mouse
negative regulation of cell cycle process GO:0010948 109 0.017
organophosphate biosynthetic process GO:0090407 46 0.017
dephosphorylation GO:0016311 51 0.017
gland development GO:0048732 191 0.017
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.017
positive regulation of apoptotic signaling pathway GO:2001235 4 0.016
vesicle organization GO:0016050 44 0.016
compound eye development GO:0048749 307 0.016
axis specification GO:0009798 167 0.016
chemotaxis GO:0006935 249 0.016
cell motility GO:0048870 251 0.016
cellular response to chemical stimulus GO:0070887 199 0.016
taxis GO:0042330 304 0.016
nucleoside triphosphate metabolic process GO:0009141 120 0.016
Worm
extracellular structure organization GO:0043062 46 0.016
protein modification process GO:0036211 438 0.016
regulation of catalytic activity GO:0050790 185 0.015
positive regulation of hydrolase activity GO:0051345 78 0.015
organophosphate catabolic process GO:0046434 112 0.015
Worm
purine nucleoside triphosphate catabolic process GO:0009146 108 0.015
Worm
immune response GO:0006955 246 0.015
regulation of mitosis GO:0007088 56 0.015
developmental pigmentation GO:0048066 68 0.015
purine ribonucleotide catabolic process GO:0009154 109 0.015
Worm
regulation of actin filament length GO:0030832 27 0.015
mitotic sister chromatid separation GO:0051306 30 0.015
carbohydrate derivative catabolic process GO:1901136 118 0.015
Worm
epithelial cell migration GO:0010631 148 0.015
trna processing GO:0008033 3 0.015
organonitrogen compound catabolic process GO:1901565 128 0.015
Worm
gonad development GO:0008406 50 0.015
appendage morphogenesis GO:0035107 397 0.015
negative regulation of molecular function GO:0044092 51 0.015
positive regulation of response to stimulus GO:0048584 323 0.015
nucleoside triphosphate catabolic process GO:0009143 108 0.015
Worm
multicellular organismal aging GO:0010259 140 0.014
striated muscle cell differentiation GO:0051146 90 0.014
Mouse
response to radiation GO:0009314 155 0.014
imaginal disc derived appendage morphogenesis GO:0035114 395 0.014
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.014
protein depolymerization GO:0051261 31 0.014
negative regulation of protein processing GO:0010955 31 0.014
extracellular matrix organization GO:0030198 32 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
protein targeting GO:0006605 64 0.014
Mouse
heterocycle catabolic process GO:0046700 166 0.014
Worm
regulation of cell morphogenesis GO:0022604 163 0.013
negative regulation of organelle organization GO:0010639 56 0.013
positive regulation of signal transduction GO:0009967 223 0.013
positive regulation of secretion GO:0051047 22 0.013
ribose phosphate metabolic process GO:0019693 145 0.013
Worm
eye morphogenesis GO:0048592 260 0.013
regulation of microtubule cytoskeleton organization GO:0070507 41 0.013
tissue migration GO:0090130 155 0.013
response to starvation GO:0042594 97 0.013
ribonucleoprotein complex subunit organization GO:0071826 28 0.013
lipid biosynthetic process GO:0008610 46 0.013
regulation of nuclear division GO:0051783 58 0.013
gravitaxis GO:0042332 26 0.013
ribonucleoprotein complex assembly GO:0022618 23 0.013
establishment of rna localization GO:0051236 47 0.013
regulation of vesicle mediated transport GO:0060627 59 0.013
Mouse
regulation of protein import into nucleus GO:0042306 28 0.013
nucleotide catabolic process GO:0009166 109 0.013
Worm
actin filament polymerization GO:0030041 27 0.013
negative regulation of biosynthetic process GO:0009890 277 0.013
microtubule based movement GO:0007018 51 0.012
regulation of cell adhesion GO:0030155 27 0.012
response to external biotic stimulus GO:0043207 293 0.012
negative regulation of signaling GO:0023057 219 0.012
meiotic cell cycle GO:0051321 171 0.012
Worm
regulation of microtubule depolymerization GO:0031114 24 0.012
regulation of synapse assembly GO:0051963 94 0.012
actin polymerization or depolymerization GO:0008154 31 0.012
negative regulation of mitotic cell cycle GO:0045930 109 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.012
translation GO:0006412 69 0.012
response to bacterium GO:0009617 198 0.012
response to lipid GO:0033993 38 0.012
autophagic cell death GO:0048102 83 0.012
negative regulation of catabolic process GO:0009895 36 0.012
cortical actin cytoskeleton organization GO:0030866 24 0.012
adult locomotory behavior GO:0008344 76 0.012
cellular component disassembly GO:0022411 46 0.012
regulation of cell death GO:0010941 173 0.011
Worm
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.011
regulation of growth GO:0040008 233 0.011
exocytosis GO:0006887 28 0.011
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.011
response to light stimulus GO:0009416 124 0.011
cytoskeleton dependent cytokinesis GO:0061640 81 0.011
single organism catabolic process GO:0044712 228 0.011
Worm
regulation of peptidase activity GO:0052547 39 0.011
negative regulation of signal transduction GO:0009968 206 0.011
positive regulation of protein complex assembly GO:0031334 22 0.011
determination of adult lifespan GO:0008340 137 0.011
purine containing compound catabolic process GO:0072523 112 0.011
Worm
response to extracellular stimulus GO:0009991 116 0.011
regulation of pole plasm oskar mrna localization GO:0007317 27 0.011
response to oxygen levels GO:0070482 59 0.011
regulation of cell cycle process GO:0010564 181 0.011
cell cycle phase transition GO:0044770 140 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
Worm
positive regulation of developmental pigmentation GO:0048087 5 0.011
imaginal disc derived wing morphogenesis GO:0007476 337 0.011
protein localization to organelle GO:0033365 82 0.011
purine ribonucleoside metabolic process GO:0046128 127 0.011
Worm
open tracheal system development GO:0007424 204 0.011
cellular response to nutrient levels GO:0031669 62 0.011
negative regulation of developmental process GO:0051093 201 0.010
response to other organism GO:0051707 293 0.010
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.010
establishment of protein localization to organelle GO:0072594 62 0.010
hematopoietic or lymphoid organ development GO:0048534 57 0.010
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.010
imaginal disc derived appendage development GO:0048737 399 0.010
negative regulation of translation GO:0017148 28 0.010
ovarian follicle cell development GO:0030707 248 0.010
appendage development GO:0048736 401 0.010

Past1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.105
retinal disease DOID:5679 0 0.032
retinal degeneration DOID:8466 0 0.032
sensory system disease DOID:0050155 0 0.032
macular degeneration DOID:4448 0 0.032
eye and adnexa disease DOID:1492 0 0.032
nervous system disease DOID:863 0 0.032
eye disease DOID:5614 0 0.032
central nervous system disease DOID:331 0 0.013
neurodegenerative disease DOID:1289 0 0.010