Drosophila melanogaster

270 known processes

Tsc1 (Dmel_CG6147)

CG6147 gene product from transcript CG6147-RA

(Aliases: CG6147,dTsc1,dTSC1,rocky,TSC,dTSC,Dmel\CG6147,tsc1,TSC1)

Tsc1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
open tracheal system development GO:0007424 204 0.985
respiratory system development GO:0060541 213 0.936
eye morphogenesis GO:0048592 260 0.923
sensory organ morphogenesis GO:0090596 260 0.916
membrane organization GO:0061024 112 0.909
compound eye photoreceptor development GO:0042051 78 0.908
trachea morphogenesis GO:0060439 22 0.853
compound eye morphogenesis GO:0001745 249 0.844
small molecule metabolic process GO:0044281 305 0.844
response to extracellular stimulus GO:0009991 116 0.836
compound eye photoreceptor cell differentiation GO:0001751 140 0.793
regulation of anatomical structure morphogenesis GO:0022603 242 0.769
autophagic vacuole fusion GO:0000046 15 0.758
organic substance transport GO:0071702 257 0.756
Human Mouse
appendage development GO:0048736 401 0.752
regulation of phosphorylation GO:0042325 147 0.750
negative regulation of developmental process GO:0051093 201 0.732
eye photoreceptor cell differentiation GO:0001754 145 0.727
nucleotide metabolic process GO:0009117 161 0.727
cellular protein modification process GO:0006464 438 0.707
Mouse
muscle structure development GO:0061061 224 0.681
Mouse
tube development GO:0035295 244 0.670
Mouse
striated muscle cell differentiation GO:0051146 90 0.668
Mouse
protein transport GO:0015031 155 0.666
regulation of cellular catabolic process GO:0031329 157 0.666
protein localization GO:0008104 284 0.664
regulation of localization GO:0032879 275 0.655
negative regulation of response to stimulus GO:0048585 258 0.654
protein modification process GO:0036211 438 0.649
Mouse
appendage morphogenesis GO:0035107 397 0.643
negative regulation of signal transduction GO:0009968 206 0.641
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.639
regulation of anatomical structure size GO:0090066 163 0.638
trachea development GO:0060438 29 0.630
negative regulation of cellular metabolic process GO:0031324 382 0.607
Human
immune response GO:0006955 246 0.601
tube morphogenesis GO:0035239 191 0.598
Mouse
regulation of nervous system development GO:0051960 248 0.597
negative regulation of cell communication GO:0010648 223 0.596
response to external biotic stimulus GO:0043207 293 0.590
positive regulation of wnt signaling pathway GO:0030177 25 0.583
negative regulation of multicellular organismal process GO:0051241 142 0.574
immune system process GO:0002376 347 0.566
circulatory system development GO:0072359 82 0.558
Mouse
single organism cellular localization GO:1902580 180 0.556
endomembrane system organization GO:0010256 119 0.537
nucleoside phosphate metabolic process GO:0006753 162 0.532
determination of adult lifespan GO:0008340 137 0.527
chemotaxis GO:0006935 249 0.525
positive regulation of phosphorus metabolic process GO:0010562 139 0.522
purine containing compound metabolic process GO:0072521 155 0.519
epithelial cell differentiation GO:0030855 322 0.518
regulation of transport GO:0051049 181 0.516
eye development GO:0001654 323 0.513
regulation of programmed cell death GO:0043067 152 0.512
post embryonic appendage morphogenesis GO:0035120 385 0.500
photoreceptor cell differentiation GO:0046530 170 0.491
growth GO:0040007 359 0.489
regulation of multicellular organismal development GO:2000026 414 0.489
single organism membrane organization GO:0044802 93 0.487
secretion GO:0046903 109 0.482
programmed cell death GO:0012501 257 0.466
negative regulation of cell death GO:0060548 81 0.465
enzyme linked receptor protein signaling pathway GO:0007167 179 0.465
regulation of protein modification process GO:0031399 112 0.450
Mouse
tissue morphogenesis GO:0048729 297 0.449
Mouse
digestive tract development GO:0048565 149 0.448
compound eye development GO:0048749 307 0.448
response to organic substance GO:0010033 284 0.446
organophosphate metabolic process GO:0019637 195 0.445
muscle organ development GO:0007517 127 0.441
regulation of phosphorus metabolic process GO:0051174 210 0.429
establishment of localization in cell GO:0051649 402 0.424
Human
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.417
death GO:0016265 284 0.417
wing disc morphogenesis GO:0007472 344 0.414
cellular catabolic process GO:0044248 372 0.414
regulation of wnt signaling pathway GO:0030111 68 0.414
catabolic process GO:0009056 409 0.410
cellular amino acid metabolic process GO:0006520 61 0.405
carbohydrate derivative metabolic process GO:1901135 217 0.397
stem cell maintenance GO:0019827 67 0.392
muscle cell differentiation GO:0042692 103 0.385
Mouse
response to nutrient levels GO:0031667 114 0.382
negative regulation of signaling GO:0023057 219 0.378
negative regulation of growth GO:0045926 84 0.375
cellular protein localization GO:0034613 160 0.374
chromosome organization GO:0051276 360 0.372
glycosyl compound catabolic process GO:1901658 112 0.371
larval development GO:0002164 104 0.370
regulation of catabolic process GO:0009894 170 0.369
imaginal disc derived appendage development GO:0048737 399 0.369
regulation of cell differentiation GO:0045595 302 0.368
regulation of cell proliferation GO:0042127 163 0.367
ribonucleoside catabolic process GO:0042454 112 0.367
ribonucleotide catabolic process GO:0009261 109 0.359
organonitrogen compound metabolic process GO:1901564 318 0.359
nucleoside phosphate catabolic process GO:1901292 110 0.358
negative regulation of organ growth GO:0046621 15 0.357
secretion by cell GO:0032940 101 0.350
nucleoside metabolic process GO:0009116 127 0.347
wnt signaling pathway GO:0016055 98 0.334
regulation of cellular component size GO:0032535 98 0.332
purine ribonucleoside metabolic process GO:0046128 127 0.318
vesicle mediated transport GO:0016192 381 0.318
reproductive behavior GO:0019098 122 0.317
intracellular transport GO:0046907 228 0.316
Human
cellular response to extracellular stimulus GO:0031668 64 0.313
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.302
intracellular signal transduction GO:0035556 300 0.297
lipid localization GO:0010876 54 0.294
positive regulation of macromolecule metabolic process GO:0010604 405 0.294
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.291
ribose phosphate metabolic process GO:0019693 145 0.289
regulation of cell development GO:0060284 215 0.284
eye photoreceptor cell development GO:0042462 81 0.284
regulation of cell morphogenesis GO:0022604 163 0.272
regulation of cell cycle GO:0051726 291 0.265
response to other organism GO:0051707 293 0.264
cell proliferation GO:0008283 299 0.264
cell death GO:0008219 279 0.261
regulation of phosphate metabolic process GO:0019220 210 0.260
embryo development ending in birth or egg hatching GO:0009792 152 0.259
Mouse
gtp catabolic process GO:0006184 72 0.259
negative regulation of intracellular signal transduction GO:1902532 57 0.254
stem cell differentiation GO:0048863 117 0.252
positive regulation of cellular protein metabolic process GO:0032270 118 0.251
oxoacid metabolic process GO:0043436 103 0.248
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.244
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.243
regulation of cell death GO:0010941 173 0.241
regulation of protein transport GO:0051223 57 0.237
negative regulation of cell differentiation GO:0045596 143 0.232
morphogenesis of an epithelium GO:0002009 276 0.229
Mouse
regulation of cellular localization GO:0060341 136 0.223
golgi to plasma membrane protein transport GO:0043001 8 0.221
epithelial cell development GO:0002064 274 0.216
purine containing compound catabolic process GO:0072523 112 0.216
stem cell development GO:0048864 79 0.212
positive regulation of cellular biosynthetic process GO:0031328 316 0.211
negative regulation of developmental growth GO:0048640 64 0.210
vesicle organization GO:0016050 44 0.208
aging GO:0007568 143 0.204
purine ribonucleotide catabolic process GO:0009154 109 0.202
regulation of growth GO:0040008 233 0.201
localization of cell GO:0051674 257 0.198
regulation of organ growth GO:0046620 42 0.197
multi multicellular organism process GO:0044706 123 0.196
muscle tissue development GO:0060537 30 0.192
Mouse
positive regulation of cell differentiation GO:0045597 64 0.190
cell growth GO:0016049 108 0.189
maintenance of location GO:0051235 73 0.187
imaginal disc derived appendage morphogenesis GO:0035114 395 0.186
phagocytosis GO:0006909 215 0.181
regulation of cellular protein metabolic process GO:0032268 243 0.180
Human Mouse
defense response to other organism GO:0098542 225 0.180
positive regulation of response to stimulus GO:0048584 323 0.178
positive regulation of signal transduction GO:0009967 223 0.176
negative regulation of programmed cell death GO:0043069 72 0.176
positive regulation of signaling GO:0023056 243 0.176
organonitrogen compound catabolic process GO:1901565 128 0.174
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.174
multicellular organismal aging GO:0010259 140 0.173
membrane fusion GO:0061025 42 0.169
cell cycle phase transition GO:0044770 140 0.169
negative regulation of mitotic cell cycle GO:0045930 109 0.168
homeostatic process GO:0042592 199 0.168
response to organic cyclic compound GO:0014070 89 0.168
carboxylic acid metabolic process GO:0019752 92 0.168
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.166
carbohydrate derivative catabolic process GO:1901136 118 0.163
organic acid metabolic process GO:0006082 103 0.162
locomotory behavior GO:0007626 176 0.162
nucleobase containing small molecule metabolic process GO:0055086 174 0.161
regulation of apoptotic process GO:0042981 130 0.160
ribonucleotide metabolic process GO:0009259 145 0.160
cytoplasmic transport GO:0016482 130 0.158
Human
somatic stem cell maintenance GO:0035019 14 0.156
heart development GO:0007507 82 0.154
Mouse
response to biotic stimulus GO:0009607 294 0.153
regulation of intracellular signal transduction GO:1902531 236 0.152
lysosomal transport GO:0007041 13 0.151
regulation of neurogenesis GO:0050767 158 0.149
phosphorylation GO:0016310 294 0.147
cellular response to chemical stimulus GO:0070887 199 0.146
guanosine containing compound metabolic process GO:1901068 74 0.146
organelle membrane fusion GO:0090174 16 0.146
cellular amine metabolic process GO:0044106 12 0.144
response to wounding GO:0009611 94 0.144
striated muscle tissue development GO:0014706 27 0.144
Mouse
positive regulation of protein modification process GO:0031401 58 0.143
photoreceptor cell development GO:0042461 96 0.143
organic substance catabolic process GO:1901575 308 0.142
establishment of protein localization GO:0045184 163 0.141
digestive tract morphogenesis GO:0048546 127 0.139
regulation of cellular amine metabolic process GO:0033238 3 0.139
positive regulation of phosphorylation GO:0042327 87 0.139
regulation of protein localization GO:0032880 76 0.138
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.136
response to nitrogen compound GO:1901698 90 0.136
positive regulation of developmental process GO:0051094 143 0.135
nucleoside triphosphate catabolic process GO:0009143 108 0.134
purine ribonucleoside catabolic process GO:0046130 112 0.133
regulation of protein metabolic process GO:0051246 256 0.132
Human Mouse
cell division GO:0051301 248 0.128
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.128
Human
adherens junction organization GO:0034332 27 0.126
Human
regulation of cell cycle process GO:0010564 181 0.125
negative regulation of nucleic acid templated transcription GO:1903507 240 0.125
cell migration GO:0016477 238 0.124
response to starvation GO:0042594 97 0.124
negative regulation of cell cycle g1 s phase transition GO:1902807 13 0.123
positive regulation of protein phosphorylation GO:0001934 34 0.123
branching morphogenesis of an epithelial tube GO:0048754 45 0.122
regulation of protein kinase activity GO:0045859 51 0.121
Mouse
hindbrain development GO:0030902 2 0.121
negative regulation of cell cycle GO:0045786 116 0.120
regulation of cytoplasmic transport GO:1903649 47 0.119
skin development GO:0043588 65 0.119
regulation of secretion GO:0051046 44 0.118
negative regulation of biosynthetic process GO:0009890 277 0.118
Human
mitotic cell cycle phase transition GO:0044772 138 0.118
protein phosphorylation GO:0006468 169 0.116
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 108 0.112
rhabdomere development GO:0042052 38 0.110
anatomical structure homeostasis GO:0060249 97 0.110
positive regulation of phosphate metabolic process GO:0045937 139 0.110
brain development GO:0007420 120 0.109
Mouse
regulation of intracellular protein transport GO:0033157 46 0.108
ovarian follicle cell development GO:0030707 248 0.107
defense response to virus GO:0051607 23 0.106
production of small rna involved in gene silencing by rna GO:0070918 15 0.106
negative regulation of rna metabolic process GO:0051253 251 0.106
purine nucleoside metabolic process GO:0042278 127 0.105
branching involved in open tracheal system development GO:0060446 45 0.105
endocytosis GO:0006897 310 0.104
lipid metabolic process GO:0006629 121 0.103
positive regulation of cellular amine metabolic process GO:0033240 0 0.103
membrane biogenesis GO:0044091 8 0.101
lipid storage GO:0019915 38 0.101
axon guidance GO:0007411 233 0.100
columnar cuboidal epithelial cell development GO:0002066 249 0.100
positive regulation of nucleotide metabolic process GO:0045981 55 0.099
regulation of mapk cascade GO:0043408 92 0.099
negative regulation of apoptotic process GO:0043066 63 0.098
transcription from rna polymerase ii promoter GO:0006366 368 0.098
intracellular protein transport GO:0006886 104 0.098
cell motility GO:0048870 251 0.097
canonical wnt signaling pathway GO:0060070 21 0.097
apoptotic process GO:0006915 159 0.097
morphogenesis of a branching epithelium GO:0061138 45 0.096
response to abiotic stimulus GO:0009628 341 0.096
signal transduction by phosphorylation GO:0023014 107 0.095
axonogenesis GO:0007409 290 0.094
regulation of transferase activity GO:0051338 58 0.094
Mouse
organ growth GO:0035265 56 0.094
developmental programmed cell death GO:0010623 138 0.093
cellular macromolecule localization GO:0070727 220 0.093
establishment of protein localization to membrane GO:0090150 11 0.092
response to endogenous stimulus GO:0009719 119 0.092
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.092
macromolecular complex assembly GO:0065003 256 0.089
striated muscle cell development GO:0055002 50 0.089
cholesterol homeostasis GO:0042632 3 0.089
purine nucleoside triphosphate catabolic process GO:0009146 108 0.089
oxidation reduction process GO:0055114 123 0.088
regulation of cell division GO:0051302 72 0.088
positive regulation of neurogenesis GO:0050769 41 0.088
embryonic morphogenesis GO:0048598 206 0.087
Mouse
single organism catabolic process GO:0044712 228 0.085
regulation of organ morphogenesis GO:2000027 78 0.084
germarium derived female germ line cyst formation GO:0030727 42 0.083
mitotic nuclear division GO:0007067 213 0.082
establishment of protein localization to plasma membrane GO:0090002 9 0.081
positive regulation of transcription dna templated GO:0045893 266 0.081
regulation of intracellular transport GO:0032386 64 0.080
cardiocyte differentiation GO:0035051 29 0.080
Mouse
peptidyl lysine modification GO:0018205 57 0.080
regulation of protein phosphorylation GO:0001932 64 0.079
Mouse
nucleoside triphosphate metabolic process GO:0009141 120 0.079
regulation of epithelial cell differentiation GO:0030856 4 0.078
negative regulation of glial cell proliferation GO:0060253 6 0.078
regulation of cellular amino acid metabolic process GO:0006521 0 0.078
negative regulation of epithelial cell proliferation GO:0050680 4 0.078
regulation of neuron differentiation GO:0045664 103 0.077
nucleobase containing compound catabolic process GO:0034655 165 0.077
cellular response to oxygen containing compound GO:1901701 79 0.077
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.076
regulation of gtp catabolic process GO:0033124 44 0.076
ribonucleoside metabolic process GO:0009119 127 0.074
regulation of developmental growth GO:0048638 174 0.074
mapk cascade GO:0000165 107 0.073
multicellular organismal reproductive behavior GO:0033057 110 0.072
regulation of epithelial cell proliferation GO:0050678 4 0.072
regulation of canonical wnt signaling pathway GO:0060828 15 0.072
positive regulation of nucleotide catabolic process GO:0030813 46 0.071
organophosphate catabolic process GO:0046434 112 0.071
guanosine containing compound catabolic process GO:1901069 74 0.070
negative regulation of cell cycle phase transition GO:1901988 103 0.069
positive regulation of protein metabolic process GO:0051247 128 0.068
amine metabolic process GO:0009308 12 0.068
body morphogenesis GO:0010171 2 0.068
regulation of cell migration GO:0030334 22 0.067
aromatic compound catabolic process GO:0019439 166 0.067
single organism membrane fusion GO:0044801 42 0.067
purine ribonucleotide metabolic process GO:0009150 145 0.067
male mating behavior GO:0060179 70 0.066
positive regulation of ras gtpase activity GO:0032320 36 0.066
chemical homeostasis GO:0048878 92 0.065
cell cell junction organization GO:0045216 55 0.065
Human
purine nucleoside catabolic process GO:0006152 112 0.064
nuclear body organization GO:0030575 6 0.064
imaginal disc derived wing morphogenesis GO:0007476 337 0.063
positive regulation of canonical wnt signaling pathway GO:0090263 7 0.063
positive regulation of catalytic activity GO:0043085 118 0.063
purine nucleoside triphosphate metabolic process GO:0009144 119 0.063
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.063
development of primary sexual characteristics GO:0045137 50 0.062
negative regulation of transcription dna templated GO:0045892 237 0.062
regulation of immune response GO:0050776 118 0.062
regulation of molecular function GO:0065009 217 0.061
cellular lipid metabolic process GO:0044255 83 0.061
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.060
protein localization to organelle GO:0033365 82 0.060
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.060
positive regulation of cell communication GO:0010647 250 0.060
epidermal cell differentiation GO:0009913 51 0.059
cell substrate adhesion GO:0031589 10 0.059
Human
purine nucleotide metabolic process GO:0006163 146 0.059
sex differentiation GO:0007548 81 0.059
defense response to gram negative bacterium GO:0050829 94 0.059
telencephalon development GO:0021537 2 0.058
Mouse
regulation of cellular ketone metabolic process GO:0010565 3 0.058
regulation of establishment of protein localization GO:0070201 61 0.057
cellular response to organonitrogen compound GO:0071417 36 0.057
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.057
regulation of innate immune response GO:0045088 71 0.057
mesenchymal cell differentiation GO:0048762 1 0.056
muscle cell development GO:0055001 50 0.055
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 13 0.054
golgi to plasma membrane transport GO:0006893 8 0.054
autophagy GO:0006914 108 0.053
cellular nitrogen compound catabolic process GO:0044270 165 0.053
morphogenesis of a branching structure GO:0001763 45 0.053
digestive system development GO:0055123 149 0.052
regulation of cell size GO:0008361 63 0.052
g1 s transition of mitotic cell cycle GO:0000082 31 0.052
regulation of gtpase activity GO:0043087 44 0.052
eye antennal disc development GO:0035214 60 0.052
reproductive system development GO:0061458 74 0.051
protein localization to nucleus GO:0034504 55 0.050
positive regulation of multicellular organismal process GO:0051240 143 0.050
nucleoside catabolic process GO:0009164 112 0.050
neuron projection guidance GO:0097485 241 0.050
regulation of purine nucleotide metabolic process GO:1900542 62 0.049
response to organonitrogen compound GO:0010243 75 0.049
epithelial tube morphogenesis GO:0060562 88 0.049
Mouse
cardioblast differentiation GO:0010002 20 0.049
larval midgut histolysis GO:0035069 22 0.049
cell cycle g1 s phase transition GO:0044843 31 0.048
rhythmic behavior GO:0007622 76 0.048
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.048
Human
mesenchymal cell development GO:0014031 1 0.048
regulation of glial cell proliferation GO:0060251 11 0.047
dormancy process GO:0022611 2 0.047
myotube differentiation GO:0014902 46 0.047
positive regulation of nervous system development GO:0051962 69 0.047
epithelial cell proliferation GO:0050673 15 0.047
gtp metabolic process GO:0046039 72 0.047
determination of bilateral symmetry GO:0009855 13 0.047
Zebrafish
specification of symmetry GO:0009799 13 0.047
Zebrafish
negative regulation of phosphorus metabolic process GO:0010563 45 0.047
covalent chromatin modification GO:0016569 106 0.046
purine nucleotide catabolic process GO:0006195 109 0.046
endosome to lysosome transport GO:0008333 7 0.046
cellular response to nitrogen compound GO:1901699 51 0.046
cardiovascular system development GO:0072358 82 0.045
Mouse
negative regulation of phosphate metabolic process GO:0045936 45 0.045
positive regulation of gtpase activity GO:0043547 43 0.044
single organism behavior GO:0044708 391 0.044
instar larval development GO:0002168 55 0.044
positive regulation of transport GO:0051050 92 0.044
protein catabolic process GO:0030163 101 0.044
negative regulation of rna biosynthetic process GO:1902679 240 0.044
organic hydroxy compound metabolic process GO:1901615 83 0.043
ras protein signal transduction GO:0007265 88 0.043
gliogenesis GO:0042063 80 0.043
head development GO:0060322 135 0.043
Mouse
negative regulation of cellular protein metabolic process GO:0032269 85 0.043
Human
gland development GO:0048732 191 0.042
regulation of immune system process GO:0002682 176 0.042
negative regulation of gene expression GO:0010629 387 0.042
Human
positive regulation of gtp catabolic process GO:0033126 43 0.042
muscle organ morphogenesis GO:0048644 7 0.041
regulation of nucleocytoplasmic transport GO:0046822 35 0.041
ribonucleoside triphosphate metabolic process GO:0009199 119 0.041
posttranscriptional regulation of gene expression GO:0010608 145 0.041
Human
negative regulation of phosphorylation GO:0042326 35 0.041
positive regulation of programmed cell death GO:0043068 62 0.041
single organism biosynthetic process GO:0044711 206 0.040
nuclear import GO:0051170 51 0.040
rhythmic process GO:0048511 106 0.040
regulation of tor signaling GO:0032006 21 0.040
epithelial cell migration GO:0010631 148 0.040
protein acylation GO:0043543 42 0.040
regulation of nucleotide catabolic process GO:0030811 48 0.039
regulation of developmental pigmentation GO:0048070 24 0.039
apoptotic signaling pathway GO:0097190 27 0.039
forebrain development GO:0030900 2 0.039
Mouse
multi organism reproductive behavior GO:0044705 121 0.039
positive regulation of cell development GO:0010720 61 0.038
border follicle cell migration GO:0007298 113 0.038
cellular response to organic substance GO:0071310 132 0.038
protein complex biogenesis GO:0070271 201 0.037
cell cell signaling involved in cell fate commitment GO:0045168 210 0.037
tissue migration GO:0090130 155 0.037
molting cycle GO:0042303 56 0.037
organelle fission GO:0048285 340 0.036
regulation of phosphatase activity GO:0010921 3 0.036
Human
cellular response to nutrient levels GO:0031669 62 0.036
positive regulation of catabolic process GO:0009896 105 0.036
glycosyl compound metabolic process GO:1901657 127 0.036
negative regulation of kinase activity GO:0033673 16 0.035
taxis GO:0042330 304 0.035
organonitrogen compound biosynthetic process GO:1901566 117 0.035
positive regulation of cellular component organization GO:0051130 156 0.035
Human
chromatin organization GO:0006325 207 0.035
negative regulation of nervous system development GO:0051961 92 0.035
cation transport GO:0006812 110 0.034
Mouse
positive regulation of cell growth GO:0030307 19 0.034
r8 cell fate specification GO:0045464 5 0.034
positive regulation of immune system process GO:0002684 68 0.033
regulation of secretion by cell GO:1903530 39 0.033
macromolecule catabolic process GO:0009057 161 0.032
camera type eye morphogenesis GO:0048593 2 0.032
protein modification by small protein conjugation or removal GO:0070647 106 0.032
cellular response to hormone stimulus GO:0032870 44 0.032
regulation of behavior GO:0050795 75 0.032
multi organism behavior GO:0051705 175 0.032
embryonic digestive tract morphogenesis GO:0048557 4 0.032
imaginal disc growth GO:0007446 37 0.032
protein import into nucleus GO:0006606 51 0.031
positive regulation of cellular catabolic process GO:0031331 95 0.031
protein targeting to nucleus GO:0044744 51 0.031
autophagic vacuole assembly GO:0000045 2 0.031
central nervous system development GO:0007417 201 0.031
Mouse
regulation of cell cycle phase transition GO:1901987 130 0.030
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.030
actin cytoskeleton organization GO:0030036 206 0.030
Human
positive regulation of biosynthetic process GO:0009891 316 0.030
tor signaling GO:0031929 32 0.030
regulation of gliogenesis GO:0014013 11 0.030
negative regulation of notch signaling pathway GO:0045746 41 0.030
negative regulation of cellular biosynthetic process GO:0031327 277 0.029
Human
response to sterol GO:0036314 34 0.029
defense response to bacterium GO:0042742 178 0.029
response to bacterium GO:0009617 198 0.029
positive regulation of molecular function GO:0044093 136 0.029
convergent extension involved in gastrulation GO:0060027 2 0.028
regulation of imaginal disc growth GO:0045570 26 0.028
peptidyl amino acid modification GO:0018193 105 0.028
myoblast migration GO:0051451 2 0.028
regulation of nuclear division GO:0051783 58 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.028
regulation of stem cell proliferation GO:0072091 40 0.027
internal peptidyl lysine acetylation GO:0018393 38 0.027
protein localization to plasma membrane GO:0072659 13 0.027
regulation of notch signaling pathway GO:0008593 100 0.027
positive regulation of kinase activity GO:0033674 25 0.027
compound eye pigmentation GO:0048072 17 0.027
regulation of mitosis GO:0007088 56 0.027
regulation of defense response GO:0031347 102 0.027
positive regulation of immune response GO:0050778 63 0.026
carbohydrate metabolic process GO:0005975 82 0.026
rhabdomere membrane biogenesis GO:0045313 6 0.026
actin filament organization GO:0007015 126 0.026
Human
ameboidal type cell migration GO:0001667 151 0.026
histone modification GO:0016570 106 0.026
negative regulation of cyclin dependent protein serine threonine kinase activity GO:0045736 1 0.026
convergent extension GO:0060026 2 0.025
cuticle development GO:0042335 86 0.025
regulation of cell motility GO:2000145 23 0.025
negative regulation of insulin receptor signaling pathway GO:0046627 11 0.025
negative regulation of tor signaling GO:0032007 5 0.025
regulation of multicellular organism growth GO:0040014 40 0.025
positive regulation of rna metabolic process GO:0051254 271 0.025
r8 cell fate commitment GO:0007460 6 0.025
salivary gland development GO:0007431 162 0.025
negative regulation of cell cycle process GO:0010948 109 0.024
regulation of cell cycle g1 s phase transition GO:1902806 23 0.024
developmental maturation GO:0021700 172 0.024
embryonic organ development GO:0048568 50 0.024
compound eye photoreceptor fate commitment GO:0001752 36 0.024

Tsc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.137
cancer DOID:162 0 0.107
organ system cancer DOID:0050686 0 0.107
disease of anatomical entity DOID:7 0 0.087