Drosophila melanogaster

50 known processes

MED14 (Dmel_CG12031)

Mediator complex subunit 14

(Aliases: Trap170,Dmel\CG12031,p160,Med14,dTRAP170,CG12031)

MED14 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of macromolecule metabolic process GO:0010604 405 0.661
protein modification process GO:0036211 438 0.429
positive regulation of response to stimulus GO:0048584 323 0.393
body morphogenesis GO:0010171 2 0.376
Worm
transcription from rna polymerase ii promoter GO:0006366 368 0.318
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.316
snrna 3 end processing GO:0034472 14 0.293
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.256
positive regulation of rna metabolic process GO:0051254 271 0.254
regulation of immune effector process GO:0002697 52 0.232
regulation of immune response GO:0050776 118 0.187
regulation of cellular protein metabolic process GO:0032268 243 0.178
positive regulation of nucleic acid templated transcription GO:1903508 266 0.178
positive regulation of transcription dna templated GO:0045893 266 0.174
positive regulation of cell communication GO:0010647 250 0.170
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.162
response to biotic stimulus GO:0009607 294 0.160
cellular response to peptide hormone stimulus GO:0071375 28 0.155
defense response GO:0006952 300 0.154
organonitrogen compound metabolic process GO:1901564 318 0.152
regulation of cell proliferation GO:0042127 163 0.145
intracellular signal transduction GO:0035556 300 0.138
immune response GO:0006955 246 0.133
vesicle mediated transport GO:0016192 381 0.132
cellular protein modification process GO:0006464 438 0.129
positive regulation of signal transduction GO:0009967 223 0.127
response to oxygen containing compound GO:1901700 200 0.119
positive regulation of biosynthetic process GO:0009891 316 0.117
regulation of cellular amino acid metabolic process GO:0006521 0 0.112
response to peptide hormone GO:0043434 29 0.111
axon development GO:0061564 297 0.109
positive regulation of cellular protein metabolic process GO:0032270 118 0.107
innate immune response GO:0045087 144 0.107
positive regulation of phosphate metabolic process GO:0045937 139 0.104
response to lipopolysaccharide GO:0032496 4 0.103
positive regulation of developmental process GO:0051094 143 0.102
regulation of intracellular signal transduction GO:1902531 236 0.101
cell cell signaling involved in cell fate commitment GO:0045168 210 0.101
regulation of cell differentiation GO:0045595 302 0.099
Mouse
wing disc morphogenesis GO:0007472 344 0.099
response to other organism GO:0051707 293 0.098
regulation of cell cycle phase transition GO:1901987 130 0.097
response to peptide GO:1901652 29 0.096
regulation of anatomical structure morphogenesis GO:0022603 242 0.091
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.089
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.088
photoreceptor cell differentiation GO:0046530 170 0.085
positive regulation of cellular biosynthetic process GO:0031328 316 0.083
positive regulation of gene expression GO:0010628 290 0.083
mitotic cell cycle phase transition GO:0044772 138 0.083
regulation of protein modification process GO:0031399 112 0.082
establishment or maintenance of cell polarity GO:0007163 167 0.078
nuclear division GO:0000280 332 0.077
regulation of cell death GO:0010941 173 0.077
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.074
positive regulation of multicellular organismal process GO:0051240 143 0.073
regulation of immune system process GO:0002682 176 0.073
positive regulation of signaling GO:0023056 243 0.069
immune effector process GO:0002252 98 0.065
eye morphogenesis GO:0048592 260 0.065
cell proliferation GO:0008283 299 0.063
negative regulation of cell proliferation GO:0008285 69 0.063
response to organic substance GO:0010033 284 0.062
biological adhesion GO:0022610 138 0.062
cellular amino acid metabolic process GO:0006520 61 0.062
humoral immune response GO:0006959 117 0.061
protein ubiquitination GO:0016567 70 0.060
cell cycle checkpoint GO:0000075 95 0.060
death GO:0016265 284 0.060
small molecule metabolic process GO:0044281 305 0.060
amine metabolic process GO:0009308 12 0.059
regulation of cell cycle process GO:0010564 181 0.058
cellular macromolecule catabolic process GO:0044265 136 0.058
eye development GO:0001654 323 0.057
cellular amine metabolic process GO:0044106 12 0.057
programmed cell death GO:0012501 257 0.057
regulation of cell morphogenesis GO:0022604 163 0.056
negative regulation of signaling GO:0023057 219 0.055
negative regulation of mitotic cell cycle GO:0045930 109 0.055
regulation of antimicrobial peptide production GO:0002784 44 0.055
catabolic process GO:0009056 409 0.054
compound eye development GO:0048749 307 0.053
production of molecular mediator of immune response GO:0002440 46 0.053
regulation of cell shape GO:0008360 113 0.052
rna 3 end processing GO:0031123 45 0.050
regulation of mapk cascade GO:0043408 92 0.050
regulation of protein metabolic process GO:0051246 256 0.049
regulation of cell development GO:0060284 215 0.049
cell adhesion GO:0007155 136 0.049
carboxylic acid metabolic process GO:0019752 92 0.048
mapk cascade GO:0000165 107 0.048
immune system process GO:0002376 347 0.048
enzyme linked receptor protein signaling pathway GO:0007167 179 0.047
cellular response to organic substance GO:0071310 132 0.047
response to organonitrogen compound GO:0010243 75 0.046
response to nitrogen compound GO:1901698 90 0.046
positive regulation of cellular amine metabolic process GO:0033240 0 0.045
mitotic g2 dna damage checkpoint GO:0007095 69 0.045
response to external biotic stimulus GO:0043207 293 0.045
stem cell maintenance GO:0019827 67 0.044
Mouse
positive regulation of rna biosynthetic process GO:1902680 266 0.044
regulation of cellular amine metabolic process GO:0033238 3 0.044
cellular response to oxygen containing compound GO:1901701 79 0.043
inositol lipid mediated signaling GO:0048017 4 0.042
negative regulation of cellular metabolic process GO:0031324 382 0.042
morphogenesis of an epithelium GO:0002009 276 0.042
growth GO:0040007 359 0.042
regulation of response to external stimulus GO:0032101 115 0.040
macromolecule catabolic process GO:0009057 161 0.040
embryonic morphogenesis GO:0048598 206 0.040
regulation of meiosis GO:0040020 3 0.039
regulation of transport GO:0051049 181 0.039
compound eye morphogenesis GO:0001745 249 0.039
gland development GO:0048732 191 0.039
regulation of production of molecular mediator of immune response GO:0002700 44 0.039
appendage development GO:0048736 401 0.038
positive regulation of phosphorylation GO:0042327 87 0.038
regulation of cellular ketone metabolic process GO:0010565 3 0.038
tube development GO:0035295 244 0.038
positive regulation of cell differentiation GO:0045597 64 0.037
regulation of mrna metabolic process GO:1903311 72 0.035
heterocycle catabolic process GO:0046700 166 0.034
regulation of phosphorus metabolic process GO:0051174 210 0.034
cellular response to organonitrogen compound GO:0071417 36 0.034
positive regulation of cellular component biogenesis GO:0044089 80 0.034
protein modification by small protein conjugation or removal GO:0070647 106 0.034
cellular response to endogenous stimulus GO:0071495 80 0.033
response to alcohol GO:0097305 95 0.033
negative regulation of signal transduction GO:0009968 206 0.033
cellular response to dna damage stimulus GO:0006974 223 0.032
cellular response to nitrogen compound GO:1901699 51 0.032
negative regulation of response to stimulus GO:0048585 258 0.032
phosphorylation GO:0016310 294 0.032
embryo development ending in birth or egg hatching GO:0009792 152 0.031
Worm
proteolysis GO:0006508 192 0.031
negative regulation of developmental process GO:0051093 201 0.031
Mouse
cardiovascular system development GO:0072358 82 0.031
positive regulation of protein metabolic process GO:0051247 128 0.031
organic substance catabolic process GO:1901575 308 0.031
cell fate determination GO:0001709 91 0.030
rna processing GO:0006396 147 0.030
developmental growth GO:0048589 280 0.030
embryonic pattern specification GO:0009880 174 0.030
regulation of cellular amide metabolic process GO:0034248 39 0.030
snrna processing GO:0016180 14 0.029
regulation of mitotic cell cycle phase transition GO:1901990 130 0.029
wnt signaling pathway GO:0016055 98 0.029
positive regulation of phosphorus metabolic process GO:0010562 139 0.029
regulation of organelle organization GO:0033043 196 0.028
neuron projection guidance GO:0097485 241 0.028
regulation of developmental growth GO:0048638 174 0.028
regulation of response to biotic stimulus GO:0002831 63 0.028
antimicrobial humoral response GO:0019730 99 0.028
regulation of phosphorylation GO:0042325 147 0.028
response to endogenous stimulus GO:0009719 119 0.028
regulation of cellular component size GO:0032535 98 0.028
positive regulation of cell proliferation GO:0008284 47 0.028
positive regulation of defense response GO:0031349 59 0.027
sensory organ morphogenesis GO:0090596 260 0.027
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.027
appendage morphogenesis GO:0035107 397 0.027
regulation of phosphate metabolic process GO:0019220 210 0.027
axonogenesis GO:0007409 290 0.027
lateral inhibition GO:0046331 206 0.027
protein modification by small protein conjugation GO:0032446 79 0.026
organic acid metabolic process GO:0006082 103 0.026
positive regulation of immune system process GO:0002684 68 0.026
regulation of defense response GO:0031347 102 0.025
regulation of molecular function GO:0065009 217 0.025
mrna metabolic process GO:0016071 124 0.025
protein phosphorylation GO:0006468 169 0.025
protein localization GO:0008104 284 0.025
hematopoietic stem cell differentiation GO:0060218 1 0.025
camera type eye development GO:0043010 4 0.025
peptide metabolic process GO:0006518 80 0.025
negative regulation of cell communication GO:0010648 223 0.025
positive regulation of endopeptidase activity GO:0010950 26 0.024
positive regulation of cellular component organization GO:0051130 156 0.024
purine ribonucleoside metabolic process GO:0046128 127 0.024
regulation of small gtpase mediated signal transduction GO:0051056 93 0.024
imaginal disc derived appendage morphogenesis GO:0035114 395 0.024
imaginal disc derived appendage development GO:0048737 399 0.023
stem cell differentiation GO:0048863 117 0.023
Mouse
cellular amide metabolic process GO:0043603 80 0.023
cellular response to hormone stimulus GO:0032870 44 0.023
response to hormone GO:0009725 45 0.023
regulation of growth GO:0040008 233 0.023
convergent extension GO:0060026 2 0.023
cellular ketone metabolic process GO:0042180 24 0.023
salivary gland development GO:0007431 162 0.023
regulation of multicellular organismal development GO:2000026 414 0.023
snrna metabolic process GO:0016073 14 0.023
exocrine system development GO:0035272 162 0.023
developmental programmed cell death GO:0010623 138 0.023
mitotic dna damage checkpoint GO:0044773 74 0.023
digestive tract development GO:0048565 149 0.022
negative regulation of cell cycle GO:0045786 116 0.022
mitotic g2 m transition checkpoint GO:0044818 70 0.022
notch signaling pathway GO:0007219 120 0.022
regulation of cell cycle GO:0051726 291 0.022
response to organic cyclic compound GO:0014070 89 0.022
ncrna metabolic process GO:0034660 43 0.022
regulation of multi organism process GO:0043900 131 0.021
formation of anatomical boundary GO:0048859 37 0.021
posttranscriptional regulation of gene expression GO:0010608 145 0.021
cellular response to peptide GO:1901653 28 0.021
organic substance transport GO:0071702 257 0.021
cell cycle phase transition GO:0044770 140 0.021
cellular response to chemical stimulus GO:0070887 199 0.021
epithelial cell differentiation GO:0030855 322 0.021
protein complex biogenesis GO:0070271 201 0.021
cellular response to organic cyclic compound GO:0071407 32 0.021
axon guidance GO:0007411 233 0.020
endocytosis GO:0006897 310 0.020
regulation of intracellular transport GO:0032386 64 0.020
regulation of mrna processing GO:0050684 71 0.019
positive regulation of catabolic process GO:0009896 105 0.019
gene silencing GO:0016458 138 0.019
response to radiation GO:0009314 155 0.018
imaginal disc pattern formation GO:0007447 91 0.018
regulation of embryonic development GO:0045995 68 0.018
defense response to other organism GO:0098542 225 0.018
post embryonic appendage morphogenesis GO:0035120 385 0.018
embryonic axis specification GO:0000578 107 0.018
regulation of cellular catabolic process GO:0031329 157 0.018
cellular protein complex assembly GO:0043623 71 0.018
tissue death GO:0016271 102 0.018
actin filament based process GO:0030029 220 0.018
cell death GO:0008219 279 0.018
ncrna 3 end processing GO:0043628 17 0.018
organelle fission GO:0048285 340 0.018
muscle structure development GO:0061061 224 0.017
negative regulation of stem cell proliferation GO:2000647 30 0.017
response to bacterium GO:0009617 198 0.017
single organism cellular localization GO:1902580 180 0.017
regulation of peptidase activity GO:0052547 39 0.017
cellular macromolecule localization GO:0070727 220 0.017
protein targeting to nucleus GO:0044744 51 0.017
cellular response to lipid GO:0071396 20 0.017
intracellular protein transport GO:0006886 104 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.016
mrna processing GO:0006397 104 0.016
negative regulation of notch signaling pathway GO:0045746 41 0.016
regulation of humoral immune response GO:0002920 51 0.016
positive regulation of mapk cascade GO:0043410 63 0.016
taxis GO:0042330 304 0.016
aromatic compound catabolic process GO:0019439 166 0.016
cellular macromolecular complex assembly GO:0034622 153 0.016
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.016
protein catabolic process GO:0030163 101 0.016
phagocytosis GO:0006909 215 0.016
regulation of cellular component biogenesis GO:0044087 201 0.016
positive regulation of protein modification process GO:0031401 58 0.015
regulation of mitotic cell cycle GO:0007346 190 0.015
single organism cell adhesion GO:0098602 47 0.015
protein transport GO:0015031 155 0.015
ameboidal type cell migration GO:0001667 151 0.015
autophagic cell death GO:0048102 83 0.015
regulation of catalytic activity GO:0050790 185 0.015
regulation of response to stress GO:0080134 200 0.015
cellular catabolic process GO:0044248 372 0.014
formation of organ boundary GO:0010160 30 0.014
intracellular transport GO:0046907 228 0.014
small gtpase mediated signal transduction GO:0007264 88 0.014
regulation of proteolysis GO:0030162 87 0.014
regulation of neural precursor cell proliferation GO:2000177 35 0.014
gonad development GO:0008406 50 0.014
modification dependent protein catabolic process GO:0019941 78 0.014
regulation of apoptotic process GO:0042981 130 0.014
epithelial cell development GO:0002064 274 0.014
actin filament polymerization GO:0030041 27 0.014
muscle organ development GO:0007517 127 0.014
gastrulation GO:0007369 70 0.014
developmental growth involved in morphogenesis GO:0060560 65 0.014
regulation of programmed cell death GO:0043067 152 0.014
gland morphogenesis GO:0022612 145 0.014
reproductive system development GO:0061458 74 0.013
protein localization to organelle GO:0033365 82 0.013
positive regulation of proteolysis GO:0045862 52 0.013
positive regulation of immune response GO:0050778 63 0.013
establishment of localization in cell GO:0051649 402 0.013
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
rna polyadenylation GO:0043631 12 0.013
mitotic cell cycle checkpoint GO:0007093 88 0.013
regulation of protein complex assembly GO:0043254 42 0.013
establishment of ommatidial planar polarity GO:0042067 49 0.013
epidermis development GO:0008544 65 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
regulation of antimicrobial humoral response GO:0002759 50 0.013
salivary gland morphogenesis GO:0007435 145 0.013
macromolecular complex assembly GO:0065003 256 0.013
nitrogen compound transport GO:0071705 85 0.012
chromatin organization GO:0006325 207 0.012
positive regulation of organelle organization GO:0010638 65 0.012
nuclear import GO:0051170 51 0.012
cellular response to ketone GO:1901655 17 0.012
protein import into nucleus GO:0006606 51 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.012
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.012
response to lipid GO:0033993 38 0.012
positive regulation of molecular function GO:0044093 136 0.012
formation of a compartment boundary GO:0060288 4 0.012
digestive system development GO:0055123 149 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.012
antimicrobial peptide production GO:0002775 46 0.012
positive regulation of transport GO:0051050 92 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
rna transport GO:0050658 46 0.012
regulation of hydrolase activity GO:0051336 97 0.012
regulation of endopeptidase activity GO:0052548 36 0.012
apoptotic process GO:0006915 159 0.012
single organism catabolic process GO:0044712 228 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.011
g2 dna damage checkpoint GO:0031572 69 0.011
development of primary sexual characteristics GO:0045137 50 0.011
single organism behavior GO:0044708 391 0.011
modification dependent macromolecule catabolic process GO:0043632 79 0.011
segmentation GO:0035282 207 0.011
negative regulation of cellular biosynthetic process GO:0031327 277 0.011
aging GO:0007568 143 0.011
salivary gland cell autophagic cell death GO:0035071 83 0.011
regulation of wnt signaling pathway GO:0030111 68 0.011
protein localization involved in establishment of planar polarity GO:0090251 3 0.011
tissue migration GO:0090130 155 0.011
dna damage checkpoint GO:0000077 78 0.011
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.011
response to ketone GO:1901654 34 0.011
digestive tract morphogenesis GO:0048546 127 0.011
regulation of ion transport GO:0043269 39 0.010
mitochondrial membrane organization GO:0007006 3 0.010
columnar cuboidal epithelial cell development GO:0002066 249 0.010
mrna 3 end processing GO:0031124 28 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.010
metal ion transport GO:0030001 74 0.010
response to wounding GO:0009611 94 0.010
positive regulation of neuron projection regeneration GO:0070572 3 0.010
anterior posterior pattern specification GO:0009952 136 0.010
protein localization to nucleus GO:0034504 55 0.010

MED14 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.121
nervous system disease DOID:863 0 0.038
benign neoplasm DOID:0060072 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
central nervous system disease DOID:331 0 0.011