Drosophila melanogaster

106 known processes

MED31 (Dmel_CG1057)

Mediator complex subunit 31

(Aliases: Med31,Dmel\CG1057,BcDNA:GM28912,dSOH1,dTRAP18,CG1057,Trap18,p36)

MED31 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of neuroblast proliferation GO:0007406 27 0.986
regulation of neuroblast proliferation GO:1902692 34 0.969
negative regulation of stem cell proliferation GO:2000647 30 0.932
negative regulation of neural precursor cell proliferation GO:2000178 27 0.744
regulation of neural precursor cell proliferation GO:2000177 35 0.736
negative regulation of cellular metabolic process GO:0031324 382 0.560
negative regulation of cell differentiation GO:0045596 143 0.486
regulation of mitotic cell cycle GO:0007346 190 0.476
transcription from rna polymerase ii promoter GO:0006366 368 0.470
negative regulation of cell development GO:0010721 62 0.387
regulation of cell development GO:0060284 215 0.375
neuroblast proliferation GO:0007405 74 0.366
neural precursor cell proliferation GO:0061351 75 0.357
negative regulation of developmental process GO:0051093 201 0.340
regulation of stem cell proliferation GO:0072091 40 0.334
dna damage checkpoint GO:0000077 78 0.309
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.303
negative regulation of cell cycle phase transition GO:1901988 103 0.295
mitotic dna integrity checkpoint GO:0044774 75 0.280
cell cycle checkpoint GO:0000075 95 0.268
negative regulation of neurogenesis GO:0050768 53 0.268
cell proliferation GO:0008283 299 0.265
regulation of cell proliferation GO:0042127 163 0.230
mitotic nuclear division GO:0007067 213 0.224
sex comb development GO:0045498 8 0.213
mitotic cell cycle checkpoint GO:0007093 88 0.209
dna integrity checkpoint GO:0031570 81 0.204
mitotic g2 dna damage checkpoint GO:0007095 69 0.198
negative regulation of mitotic cell cycle GO:0045930 109 0.193
stem cell proliferation GO:0072089 88 0.169
negative regulation of gene expression GO:0010629 387 0.164
dendrite development GO:0016358 204 0.163
negative regulation of cell proliferation GO:0008285 69 0.153
regulation of multicellular organismal development GO:2000026 414 0.153
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.149
negative regulation of nervous system development GO:0051961 92 0.141
mitotic cell cycle phase transition GO:0044772 138 0.132
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.127
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.125
mitotic dna damage checkpoint GO:0044773 74 0.124
innate immune response GO:0045087 144 0.111
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.108
phagocytosis GO:0006909 215 0.103
regulation of intracellular signal transduction GO:1902531 236 0.102
growth GO:0040007 359 0.096
cell cycle phase transition GO:0044770 140 0.094
rna processing GO:0006396 147 0.093
mrna processing GO:0006397 104 0.083
cell division GO:0051301 248 0.079
regulation of mitotic cell cycle phase transition GO:1901990 130 0.079
jak stat cascade GO:0007259 49 0.072
mitotic g2 m transition checkpoint GO:0044818 70 0.071
regulation of cell cycle phase transition GO:1901987 130 0.071
mrna metabolic process GO:0016071 124 0.070
negative regulation of response to stimulus GO:0048585 258 0.069
positive regulation of response to stimulus GO:0048584 323 0.068
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.064
regulation of immune system process GO:0002682 176 0.064
dna templated transcription initiation GO:0006352 25 0.063
positive regulation of signal transduction GO:0009967 223 0.060
exocrine system development GO:0035272 162 0.059
negative regulation of multicellular organismal process GO:0051241 142 0.058
chromatin modification GO:0016568 147 0.057
positive regulation of nucleic acid templated transcription GO:1903508 266 0.056
negative regulation of cell cycle process GO:0010948 109 0.055
response to sterol GO:0036314 34 0.054
protein localization GO:0008104 284 0.052
organic substance catabolic process GO:1901575 308 0.051
neuron remodeling GO:0016322 29 0.049
regulation of immune response GO:0050776 118 0.048
mrna splicing via spliceosome GO:0000398 73 0.048
multicellular organismal reproductive behavior GO:0033057 110 0.046
regionalization GO:0003002 416 0.046
body morphogenesis GO:0010171 2 0.046
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.046
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.044
organic cyclic compound catabolic process GO:1901361 168 0.044
protein localization to organelle GO:0033365 82 0.043
negative regulation of cell cycle GO:0045786 116 0.043
organelle assembly GO:0070925 198 0.042
catabolic process GO:0009056 409 0.041
maintenance of location GO:0051235 73 0.041
dendrite morphogenesis GO:0048813 199 0.041
regulation of nervous system development GO:0051960 248 0.039
g2 dna damage checkpoint GO:0031572 69 0.039
regulation of cell cycle process GO:0010564 181 0.038
immune system process GO:0002376 347 0.037
cell death GO:0008219 279 0.037
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.037
immune response GO:0006955 246 0.036
muscle structure development GO:0061061 224 0.036
mrna 3 end processing GO:0031124 28 0.036
regulation of innate immune response GO:0045088 71 0.036
positive regulation of gene expression GO:0010628 290 0.036
somatic stem cell division GO:0048103 37 0.036
microtubule organizing center organization GO:0031023 168 0.036
positive regulation of cellular biosynthetic process GO:0031328 316 0.036
rna splicing GO:0008380 83 0.036
cell maturation GO:0048469 144 0.035
stem cell maintenance GO:0019827 67 0.035
response to organic cyclic compound GO:0014070 89 0.035
biological adhesion GO:0022610 138 0.034
nucleocytoplasmic transport GO:0006913 72 0.034
salivary gland morphogenesis GO:0007435 145 0.034
cell cell signaling involved in cell fate commitment GO:0045168 210 0.034
developmental growth GO:0048589 280 0.033
developmental programmed cell death GO:0010623 138 0.033
small molecule metabolic process GO:0044281 305 0.032
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.032
regulation of protein localization GO:0032880 76 0.032
vesicle mediated transport GO:0016192 381 0.032
salivary gland cell autophagic cell death GO:0035071 83 0.032
single organism nuclear import GO:1902593 51 0.031
response to ecdysone GO:0035075 34 0.031
aromatic compound catabolic process GO:0019439 166 0.031
developmental maturation GO:0021700 172 0.030
cellular macromolecule localization GO:0070727 220 0.030
organelle fission GO:0048285 340 0.030
Yeast
regulation of neurogenesis GO:0050767 158 0.030
endocytosis GO:0006897 310 0.029
germ line stem cell maintenance GO:0030718 50 0.029
atp dependent chromatin remodeling GO:0043044 22 0.029
positive regulation of transcription dna templated GO:0045893 266 0.029
macromolecular complex assembly GO:0065003 256 0.029
oviposition GO:0018991 19 0.029
cellular catabolic process GO:0044248 372 0.028
positive regulation of macromolecule metabolic process GO:0010604 405 0.028
regulation of mrna metabolic process GO:1903311 72 0.028
phosphorylation GO:0016310 294 0.028
regulation of growth GO:0040008 233 0.028
autophagic cell death GO:0048102 83 0.027
regulation of cell cycle GO:0051726 291 0.027
regulation of mrna processing GO:0050684 71 0.027
salivary gland development GO:0007431 162 0.027
positive regulation of intracellular signal transduction GO:1902533 116 0.026
protein complex biogenesis GO:0070271 201 0.026
cellular nitrogen compound catabolic process GO:0044270 165 0.026
sister chromatid segregation GO:0000819 92 0.025
Yeast
positive regulation of rna metabolic process GO:0051254 271 0.025
small gtpase mediated signal transduction GO:0007264 88 0.025
positive regulation of apoptotic process GO:0043065 47 0.025
protein import into nucleus GO:0006606 51 0.025
multi multicellular organism process GO:0044706 123 0.024
response to ketone GO:1901654 34 0.024
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.024
regulation of cell death GO:0010941 173 0.023
muscle organ development GO:0007517 127 0.023
methylation GO:0032259 47 0.023
positive regulation of programmed cell death GO:0043068 62 0.023
intracellular transport GO:0046907 228 0.023
cellular protein localization GO:0034613 160 0.022
protein import GO:0017038 55 0.022
regulation of cell differentiation GO:0045595 302 0.022
lateral inhibition GO:0046331 206 0.022
cytoplasmic transport GO:0016482 130 0.022
apoptotic process GO:0006915 159 0.021
mushroom body development GO:0016319 70 0.021
death GO:0016265 284 0.021
regulation of rna splicing GO:0043484 69 0.021
heterocycle catabolic process GO:0046700 166 0.021
spindle organization GO:0007051 253 0.020
cellular response to organic cyclic compound GO:0071407 32 0.020
regulation of catabolic process GO:0009894 170 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.020
neuron maturation GO:0042551 31 0.020
chromosome condensation GO:0030261 41 0.020
organonitrogen compound metabolic process GO:1901564 318 0.020
centriole replication GO:0007099 24 0.020
salivary gland histolysis GO:0035070 88 0.019
oocyte construction GO:0007308 112 0.019
protein targeting GO:0006605 64 0.019
stem cell development GO:0048864 79 0.019
positive regulation of cell cycle GO:0045787 43 0.019
organic substance transport GO:0071702 257 0.019
gland morphogenesis GO:0022612 145 0.018
maintenance of protein location in cell GO:0032507 26 0.018
protein transport GO:0015031 155 0.018
regulation of cellular localization GO:0060341 136 0.018
defense response to bacterium GO:0042742 178 0.018
mitotic sister chromatid segregation GO:0000070 87 0.018
stem cell division GO:0017145 69 0.017
centrosome duplication GO:0051298 121 0.017
rna localization GO:0006403 115 0.017
regulation of mrna splicing via spliceosome GO:0048024 64 0.017
negative regulation of cellular biosynthetic process GO:0031327 277 0.017
positive regulation of biosynthetic process GO:0009891 316 0.017
ras protein signal transduction GO:0007265 88 0.017
single organism catabolic process GO:0044712 228 0.016
positive regulation of developmental process GO:0051094 143 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
Yeast
plasma membrane organization GO:0007009 26 0.016
intracellular signal transduction GO:0035556 300 0.016
chaeta development GO:0022416 97 0.016
protein modification by small protein removal GO:0070646 28 0.016
macromolecule catabolic process GO:0009057 161 0.016
negative regulation of signal transduction GO:0009968 206 0.015
positive regulation of mrna catabolic process GO:0061014 5 0.015
centrosome cycle GO:0007098 137 0.015
histone exchange GO:0043486 21 0.015
single organism membrane organization GO:0044802 93 0.015
negative regulation of immune response GO:0050777 39 0.014
meiotic dna double strand break formation GO:0042138 1 0.014
regulation of ras protein signal transduction GO:0046578 93 0.014
social behavior GO:0035176 4 0.014
response to light stimulus GO:0009416 124 0.014
tissue death GO:0016271 102 0.014
ncrna metabolic process GO:0034660 43 0.014
oocyte axis specification GO:0007309 108 0.014
oocyte differentiation GO:0009994 145 0.014
dna conformation change GO:0071103 105 0.014
reproductive behavior GO:0019098 122 0.014
dorsal closure GO:0007391 79 0.013
positive regulation of apoptotic signaling pathway GO:2001235 4 0.013
rna 3 end processing GO:0031123 45 0.013
positive regulation of cell communication GO:0010647 250 0.013
immune effector process GO:0002252 98 0.013
protein alkylation GO:0008213 43 0.013
cellular response to lipopolysaccharide GO:0071222 3 0.013
response to organonitrogen compound GO:0010243 75 0.013
positive regulation of defense response GO:0031349 59 0.013
regulation of jak stat cascade GO:0046425 43 0.013
posttranscriptional gene silencing by rna GO:0035194 45 0.013
protein heterooligomerization GO:0051291 4 0.013
organophosphate metabolic process GO:0019637 195 0.012
nuclear transport GO:0051169 72 0.012
segmentation GO:0035282 207 0.012
positive regulation of cell death GO:0010942 69 0.012
histolysis GO:0007559 102 0.012
cellular response to organic substance GO:0071310 132 0.012
multi organism reproductive behavior GO:0044705 121 0.012
compound eye development GO:0048749 307 0.012
proteolysis GO:0006508 192 0.012
cellular response to lipid GO:0071396 20 0.012
positive regulation of mitotic cell cycle GO:0045931 34 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.012
reproductive system development GO:0061458 74 0.012
nuclear division GO:0000280 332 0.012
Yeast
posttranscriptional regulation of gene expression GO:0010608 145 0.012
positive regulation of rna biosynthetic process GO:1902680 266 0.012
chromatin remodeling GO:0006338 72 0.012
dephosphorylation GO:0016311 51 0.012
chromatin organization GO:0006325 207 0.012
eye photoreceptor cell differentiation GO:0001754 145 0.011
response to organic substance GO:0010033 284 0.011
histone methylation GO:0016571 40 0.011
oxidation reduction process GO:0055114 123 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
peptide biosynthetic process GO:0043043 42 0.011
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.011
rna transport GO:0050658 46 0.011
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.011
rna splicing via transesterification reactions GO:0000375 73 0.011
axonogenesis GO:0007409 290 0.011
extrinsic apoptotic signaling pathway GO:0097191 1 0.011
cellular hormone metabolic process GO:0034754 23 0.010
establishment of nucleus localization GO:0040023 26 0.010
establishment of localization in cell GO:0051649 402 0.010
negative regulation of signaling GO:0023057 219 0.010
dna packaging GO:0006323 91 0.010
cellular response to uv GO:0034644 12 0.010
male pronucleus assembly GO:0035039 6 0.010
retina development in camera type eye GO:0060041 4 0.010
execution phase of apoptosis GO:0097194 7 0.010

MED31 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
synucleinopathy DOID:0050890 0 0.035
central nervous system disease DOID:331 0 0.035
disease of anatomical entity DOID:7 0 0.035
neurodegenerative disease DOID:1289 0 0.035
nervous system disease DOID:863 0 0.035
sensory system disease DOID:0050155 0 0.010