Drosophila melanogaster

111 known processes

Taf4 (Dmel_CG5444)

TBP-associated factor 4

(Aliases: dTAF4,l(3)72Dj,SY3-2 TAF110,Taf[[II]]110,Dmel\CG5444,CG5444,TAF[[II]],TAFII110,TAF,TAF110,p110,d110,SR3-3,dTAF[[II]]110,TFIID 110,TAF[[II]]110,taf110,TAF[II]110,dTAFII110,TAF4,dmTAF4,Taf110,TFIID)

Taf4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna templated transcription initiation GO:0006352 25 0.954
dendrite morphogenesis GO:0048813 199 0.783
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.736
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 20 0.731
axon development GO:0061564 297 0.723
positive regulation of transcription dna templated GO:0045893 266 0.716
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.714
axonogenesis GO:0007409 290 0.677
growth GO:0040007 359 0.621
mrna splicing via spliceosome GO:0000398 73 0.566
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.563
positive regulation of nucleic acid templated transcription GO:1903508 266 0.558
protein dna complex subunit organization GO:0071824 86 0.554
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.547
positive regulation of rna metabolic process GO:0051254 271 0.519
dna templated transcriptional preinitiation complex assembly GO:0070897 20 0.500
photoreceptor cell differentiation GO:0046530 170 0.478
positive regulation of response to stimulus GO:0048584 323 0.437
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.425
positive regulation of rna biosynthetic process GO:1902680 266 0.407
positive regulation of gene expression GO:0010628 290 0.397
dendrite development GO:0016358 204 0.383
imaginal disc derived appendage development GO:0048737 399 0.364
regulation of cell proliferation GO:0042127 163 0.355
axon guidance GO:0007411 233 0.346
rna splicing via transesterification reactions GO:0000375 73 0.325
telencephalon development GO:0021537 2 0.305
g2 m transition of mitotic cell cycle GO:0000086 19 0.302
positive regulation of cellular biosynthetic process GO:0031328 316 0.298
forebrain development GO:0030900 2 0.294
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.276
post embryonic appendage morphogenesis GO:0035120 385 0.275
cell proliferation GO:0008283 299 0.269
developmental growth GO:0048589 280 0.255
cellular macromolecular complex assembly GO:0034622 153 0.254
negative regulation of gene expression GO:0010629 387 0.254
regulation of growth GO:0040008 233 0.254
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.247
regulation of mitotic cell cycle GO:0007346 190 0.246
macromolecular complex assembly GO:0065003 256 0.240
neuron projection guidance GO:0097485 241 0.236
cell migration GO:0016477 238 0.220
neuron fate commitment GO:0048663 50 0.217
negative regulation of nucleic acid templated transcription GO:1903507 240 0.216
positive regulation of macromolecule metabolic process GO:0010604 405 0.216
hair cell differentiation GO:0035315 47 0.209
protein modification by small protein conjugation GO:0032446 79 0.203
imaginal disc derived appendage morphogenesis GO:0035114 395 0.203
muscle structure development GO:0061061 224 0.201
gonad development GO:0008406 50 0.196
Mouse
negative regulation of biosynthetic process GO:0009890 277 0.188
taxis GO:0042330 304 0.185
muscle cell development GO:0055001 50 0.184
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.181
neuronal stem cell maintenance GO:0097150 4 0.181
immune system process GO:0002376 347 0.174
regulation of cell death GO:0010941 173 0.172
mrna metabolic process GO:0016071 124 0.169
spermatid differentiation GO:0048515 114 0.167
negative regulation of transcription dna templated GO:0045892 237 0.166
cellular catabolic process GO:0044248 372 0.164
rna splicing GO:0008380 83 0.164
negative regulation of developmental process GO:0051093 201 0.155
negative regulation of rna biosynthetic process GO:1902679 240 0.155
response to organic substance GO:0010033 284 0.153
cellular component assembly involved in morphogenesis GO:0010927 151 0.153
organic substance catabolic process GO:1901575 308 0.146
stem cell differentiation GO:0048863 117 0.145
vesicle mediated transport GO:0016192 381 0.142
chromatin organization GO:0006325 207 0.141
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.140
regulation of mrna splicing via spliceosome GO:0048024 64 0.137
cellular response to chemical stimulus GO:0070887 199 0.133
regulation of programmed cell death GO:0043067 152 0.130
appendage morphogenesis GO:0035107 397 0.125
anterior posterior pattern specification GO:0009952 136 0.124
regulation of neuroblast proliferation GO:1902692 34 0.123
male gamete generation GO:0048232 201 0.122
single organism membrane organization GO:0044802 93 0.120
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.110
dna integrity checkpoint GO:0031570 81 0.107
regulation of chromatin silencing GO:0031935 36 0.106
gene silencing GO:0016458 138 0.105
organelle fission GO:0048285 340 0.104
r7 cell differentiation GO:0045466 43 0.103
regulation of phosphorylation GO:0042325 147 0.103
eye morphogenesis GO:0048592 260 0.103
muscle cell differentiation GO:0042692 103 0.102
cellular response to dna damage stimulus GO:0006974 223 0.095
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.095
compound eye photoreceptor cell differentiation GO:0001751 140 0.094
protein modification process GO:0036211 438 0.094
eye development GO:0001654 323 0.093
chromosome organization GO:0051276 360 0.091
myoblast fusion GO:0007520 43 0.091
reproductive system development GO:0061458 74 0.090
Mouse
eye photoreceptor cell development GO:0042462 81 0.084
negative regulation of rna metabolic process GO:0051253 251 0.083
mitotic cell cycle phase transition GO:0044772 138 0.083
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.080
catabolic process GO:0009056 409 0.080
regulation of cell cycle process GO:0010564 181 0.080
wing disc morphogenesis GO:0007472 344 0.079
death GO:0016265 284 0.078
programmed cell death GO:0012501 257 0.078
protein dna complex assembly GO:0065004 63 0.078
regulation of response to biotic stimulus GO:0002831 63 0.077
negative regulation of gene expression epigenetic GO:0045814 77 0.077
establishment of planar polarity GO:0001736 87 0.075
regulation of apoptotic process GO:0042981 130 0.075
multi organism behavior GO:0051705 175 0.074
tissue migration GO:0090130 155 0.073
histone deubiquitination GO:0016578 8 0.072
cellular response to growth factor stimulus GO:0071363 30 0.072
protein complex assembly GO:0006461 200 0.071
regulation of molecular function GO:0065009 217 0.071
sex differentiation GO:0007548 81 0.070
Mouse
regionalization GO:0003002 416 0.069
chromatin silencing GO:0006342 76 0.069
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.068
cellular macromolecule catabolic process GO:0044265 136 0.067
striated muscle cell development GO:0055002 50 0.066
regulation of gene expression epigenetic GO:0040029 128 0.066
g2 dna damage checkpoint GO:0031572 69 0.066
response to other organism GO:0051707 293 0.065
adult behavior GO:0030534 137 0.065
regulation of cell cycle phase transition GO:1901987 130 0.065
stem cell maintenance GO:0019827 67 0.062
locomotory behavior GO:0007626 176 0.062
hindbrain development GO:0030902 2 0.061
mitotic g2 m transition checkpoint GO:0044818 70 0.060
establishment of tissue polarity GO:0007164 87 0.060
multicellular organismal reproductive behavior GO:0033057 110 0.059
cell cycle phase transition GO:0044770 140 0.059
negative regulation of cellular biosynthetic process GO:0031327 277 0.057
protein ubiquitination GO:0016567 70 0.055
regulation of compound eye cone cell fate specification GO:0042682 4 0.055
malpighian tubule morphogenesis GO:0007443 44 0.055
alternative mrna splicing via spliceosome GO:0000380 60 0.055
rna processing GO:0006396 147 0.054
appendage development GO:0048736 401 0.054
protein complex biogenesis GO:0070271 201 0.052
transcription from rna polymerase ii promoter GO:0006366 368 0.052
regulation of synapse structure and activity GO:0050803 128 0.052
adult locomotory behavior GO:0008344 76 0.051
proteolysis GO:0006508 192 0.050
embryonic morphogenesis GO:0048598 206 0.049
positive regulation of biosynthetic process GO:0009891 316 0.049
mrna processing GO:0006397 104 0.048
endocytosis GO:0006897 310 0.048
stem cell development GO:0048864 79 0.047
sensory organ morphogenesis GO:0090596 260 0.046
reproductive structure development GO:0048608 74 0.045
Mouse
regulation of tube size GO:0035150 46 0.044
regulation of cellular response to growth factor stimulus GO:0090287 13 0.044
response to endogenous stimulus GO:0009719 119 0.044
imaginal disc derived wing morphogenesis GO:0007476 337 0.043
body morphogenesis GO:0010171 2 0.042
negative regulation of cellular metabolic process GO:0031324 382 0.042
mitotic cell cycle embryonic GO:0045448 38 0.041
apoptotic process GO:0006915 159 0.041
chromatin modification GO:0016568 147 0.040
embryonic development via the syncytial blastoderm GO:0001700 148 0.040
spermatogenesis GO:0007283 200 0.040
photoreceptor cell development GO:0042461 96 0.039
organic cyclic compound catabolic process GO:1901361 168 0.038
multi organism reproductive behavior GO:0044705 121 0.038
single organism behavior GO:0044708 391 0.038
glial cell differentiation GO:0010001 35 0.038
mitotic g2 dna damage checkpoint GO:0007095 69 0.038
epithelial cell differentiation GO:0030855 322 0.037
negative regulation of neuroblast proliferation GO:0007406 27 0.037
positive regulation of protein complex assembly GO:0031334 22 0.037
dna templated transcription elongation GO:0006354 18 0.037
neuron recognition GO:0008038 101 0.036
stem cell fate commitment GO:0048865 25 0.036
cellular nitrogen compound catabolic process GO:0044270 165 0.036
compound eye photoreceptor development GO:0042051 78 0.036
regulation of cellular component biogenesis GO:0044087 201 0.035
multicellular organism growth GO:0035264 46 0.035
respiratory system development GO:0060541 213 0.035
regulation of gene silencing GO:0060968 63 0.035
positive regulation of cell communication GO:0010647 250 0.035
developmental maturation GO:0021700 172 0.035
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.034
development of primary sexual characteristics GO:0045137 50 0.033
Mouse
pigmentation GO:0043473 75 0.033
striated muscle cell differentiation GO:0051146 90 0.033
organic substance transport GO:0071702 257 0.033
macromolecule catabolic process GO:0009057 161 0.033
mitotic sister chromatid segregation GO:0000070 87 0.032
sister chromatid segregation GO:0000819 92 0.032
eye photoreceptor cell differentiation GO:0001754 145 0.032
regulation of rna splicing GO:0043484 69 0.032
spermatid development GO:0007286 98 0.031
negative regulation of cell communication GO:0010648 223 0.031
imaginal disc derived wing hair organization GO:0035317 45 0.031
gland morphogenesis GO:0022612 145 0.031
positive regulation of cellular component organization GO:0051130 156 0.031
morphogenesis of a polarized epithelium GO:0001738 93 0.031
epidermis development GO:0008544 65 0.031
nephron epithelium morphogenesis GO:0072088 3 0.030
internal protein amino acid acetylation GO:0006475 38 0.030
negative regulation of cell death GO:0060548 81 0.030
regulation of cell cycle GO:0051726 291 0.030
regulation of anatomical structure morphogenesis GO:0022603 242 0.029
aromatic compound catabolic process GO:0019439 166 0.029
cellular protein localization GO:0034613 160 0.029
cell recognition GO:0008037 102 0.029
negative regulation of multicellular organismal process GO:0051241 142 0.028
histone modification GO:0016570 106 0.028
outflow tract morphogenesis GO:0003151 4 0.028
regulation of mrna metabolic process GO:1903311 72 0.028
open tracheal system development GO:0007424 204 0.027
positive regulation of signal transduction GO:0009967 223 0.027
cell death GO:0008219 279 0.027
myotube cell development GO:0014904 3 0.027
skin development GO:0043588 65 0.026
protein catabolic process GO:0030163 101 0.026
nucleobase containing compound catabolic process GO:0034655 165 0.026
regulation of erbb signaling pathway GO:1901184 42 0.026
central nervous system development GO:0007417 201 0.025
response to lipopolysaccharide GO:0032496 4 0.025
positive regulation of catabolic process GO:0009896 105 0.025
single organism catabolic process GO:0044712 228 0.025
cell growth GO:0016049 108 0.025
cellular response to insulin stimulus GO:0032869 28 0.025
protein modification by small protein conjugation or removal GO:0070647 106 0.025
chromatin remodeling GO:0006338 72 0.025
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.024
negative regulation of protein metabolic process GO:0051248 85 0.024
regulation of phosphorus metabolic process GO:0051174 210 0.024
positive regulation of signaling GO:0023056 243 0.024
regulation of meiosis GO:0040020 3 0.024
cellular macromolecule localization GO:0070727 220 0.024
mitotic cell cycle checkpoint GO:0007093 88 0.023
sarcomere organization GO:0045214 26 0.023
imaginal disc pattern formation GO:0007447 91 0.023
compound eye photoreceptor fate commitment GO:0001752 36 0.023
eye photoreceptor cell fate commitment GO:0042706 37 0.023
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.023
male sex differentiation GO:0046661 25 0.022
regulation of dna templated transcription elongation GO:0032784 17 0.022
morphogenesis of an epithelium GO:0002009 276 0.022
chromatin mediated maintenance of transcription GO:0048096 7 0.022
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.022
dna methylation or demethylation GO:0044728 4 0.022
dna damage checkpoint GO:0000077 78 0.022
muscle fiber development GO:0048747 12 0.022
positive regulation of immune system process GO:0002684 68 0.022
cellular protein modification process GO:0006464 438 0.021
compound eye development GO:0048749 307 0.021
head development GO:0060322 135 0.021
skeletal muscle fiber development GO:0048741 3 0.021
meiosis i GO:0007127 59 0.021
rrna processing GO:0006364 3 0.021
antimicrobial humoral response GO:0019730 99 0.021
r1 r6 cell differentiation GO:0048052 4 0.021
positive regulation of growth GO:0045927 75 0.021
signal transduction by phosphorylation GO:0023014 107 0.021
response to bacterium GO:0009617 198 0.021
negative regulation of molecular function GO:0044092 51 0.021
epithelial structure maintenance GO:0010669 17 0.020
regulation of mrna processing GO:0050684 71 0.020
myofibril assembly GO:0030239 36 0.020
negative regulation of cellular catabolic process GO:0031330 34 0.020
response to nutrient levels GO:0031667 114 0.020
response to biotic stimulus GO:0009607 294 0.020
renal tubule development GO:0061326 64 0.019
regulation of cellular catabolic process GO:0031329 157 0.019
peptidyl lysine acetylation GO:0018394 39 0.019
establishment of localization in cell GO:0051649 402 0.019
dna repair GO:0006281 54 0.019
heterocycle catabolic process GO:0046700 166 0.019
immune system development GO:0002520 57 0.019
sensory perception GO:0007600 196 0.019
negative regulation of cell cycle phase transition GO:1901988 103 0.019
non sensory hair organization GO:0035316 47 0.019
regulation of developmental growth GO:0048638 174 0.019
negative regulation of cell proliferation GO:0008285 69 0.019
meiotic nuclear division GO:0007126 151 0.019
regulation of mitotic cell cycle phase transition GO:1901990 130 0.018
phosphate ion transport GO:0006817 4 0.018
meiotic chromosome condensation GO:0010032 3 0.018
cell cycle checkpoint GO:0000075 95 0.018
phosphorylation GO:0016310 294 0.018
mitotic dna integrity checkpoint GO:0044774 75 0.018
regulation of multi organism process GO:0043900 131 0.018
brain development GO:0007420 120 0.018
regulation of phosphate metabolic process GO:0019220 210 0.018
mating GO:0007618 120 0.018
positive regulation of cellular component biogenesis GO:0044089 80 0.017
nuclear division GO:0000280 332 0.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.017
chemotaxis GO:0006935 249 0.017
compound eye cone cell fate commitment GO:0042676 5 0.017
dna metabolic process GO:0006259 227 0.017
epidermal cell differentiation GO:0009913 51 0.017
regulation of response to stress GO:0080134 200 0.017
establishment or maintenance of cell polarity GO:0007163 167 0.017
negative regulation of cell cycle process GO:0010948 109 0.017
multi multicellular organism process GO:0044706 123 0.017
positive regulation of developmental process GO:0051094 143 0.017
meiotic spindle organization GO:0000212 36 0.017
regulation of organ morphogenesis GO:2000027 78 0.017
protein import GO:0017038 55 0.016
embryonic hindgut morphogenesis GO:0048619 48 0.016
negative regulation of cell differentiation GO:0045596 143 0.016
actin cytoskeleton organization GO:0030036 206 0.016
autophagic cell death GO:0048102 83 0.016
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.016
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.016
organelle assembly GO:0070925 198 0.016
positive regulation of intracellular signal transduction GO:1902533 116 0.016
regulation of catalytic activity GO:0050790 185 0.016
neuroblast differentiation GO:0014016 29 0.015
meiotic cell cycle GO:0051321 171 0.015
mesenchymal cell development GO:0014031 1 0.015
positive regulation of response to external stimulus GO:0032103 44 0.015
digestive system development GO:0055123 149 0.015
erbb signaling pathway GO:0038127 58 0.015
neuroblast proliferation GO:0007405 74 0.015
dna methylation GO:0006306 4 0.015
response to organic cyclic compound GO:0014070 89 0.015
regulation of protein localization GO:0032880 76 0.015
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.015
protein localization GO:0008104 284 0.015
tissue morphogenesis GO:0048729 297 0.015
wing disc dorsal ventral pattern formation GO:0048190 47 0.015
ribonucleoprotein complex biogenesis GO:0022613 31 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.015
imaginal disc growth GO:0007446 37 0.014
regulation of intracellular signal transduction GO:1902531 236 0.014
centriole replication GO:0007099 24 0.014
regulation of humoral immune response GO:0002920 51 0.014
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.014
mitotic dna damage checkpoint GO:0044773 74 0.014
phagocytosis GO:0006909 215 0.014
renal tubule morphogenesis GO:0061333 44 0.014
posttranscriptional regulation of gene expression GO:0010608 145 0.014
intracellular transport GO:0046907 228 0.014
organonitrogen compound metabolic process GO:1901564 318 0.014
protein modification by small protein removal GO:0070646 28 0.014
cell division GO:0051301 248 0.014
defense response to other organism GO:0098542 225 0.013
dosage compensation GO:0007549 16 0.013
hindgut development GO:0061525 58 0.013
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 15 0.013
response to oxygen levels GO:0070482 59 0.013
response to alcohol GO:0097305 95 0.013
organophosphate metabolic process GO:0019637 195 0.013
negative regulation of mitotic cell cycle GO:0045930 109 0.013
regulation of chromosome organization GO:0033044 64 0.013
metaphase anaphase transition of cell cycle GO:0044784 28 0.013
regulation of cellular response to stress GO:0080135 89 0.013
gland development GO:0048732 191 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
regulation of multicellular organismal development GO:2000026 414 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.012
photoreceptor cell fate commitment GO:0046552 41 0.012
histolysis GO:0007559 102 0.012
positive regulation of molecular function GO:0044093 136 0.012
negative regulation of catabolic process GO:0009895 36 0.012
rna catabolic process GO:0006401 37 0.012
wing disc pattern formation GO:0035222 66 0.012
developmental growth involved in morphogenesis GO:0060560 65 0.012
regulation of dna binding GO:0051101 10 0.012
muscle organ development GO:0007517 127 0.012
neuron projection extension GO:1990138 32 0.012
hemopoiesis GO:0030097 46 0.012
positive regulation of cell death GO:0010942 69 0.012
regulation of catabolic process GO:0009894 170 0.011
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 16 0.011
single organism biosynthetic process GO:0044711 206 0.011
protein localization to organelle GO:0033365 82 0.011
actomyosin structure organization GO:0031032 56 0.011
negative regulation of programmed cell death GO:0043069 72 0.011
receptor mediated endocytosis GO:0006898 21 0.011
morphogenesis of follicular epithelium GO:0016333 36 0.011
tissue death GO:0016271 102 0.011
cellular response to hormone stimulus GO:0032870 44 0.011
mitotic nuclear division GO:0007067 213 0.011
nuclear transcribed mrna catabolic process GO:0000956 24 0.011
synaptic transmission GO:0007268 288 0.011
regulation of cell fate specification GO:0042659 27 0.011
sensory perception of sound GO:0007605 56 0.011
myotube differentiation GO:0014902 46 0.011
regulation of protein complex assembly GO:0043254 42 0.011
intracellular protein transport GO:0006886 104 0.011
posttranscriptional gene silencing GO:0016441 46 0.011
cellular response to endogenous stimulus GO:0071495 80 0.011
pupal development GO:0035209 11 0.010
nuclear transcribed mrna poly a tail shortening GO:0000289 12 0.010
epithelium migration GO:0090132 148 0.010
protein kinase b signaling GO:0043491 1 0.010
positive regulation of chromatin silencing GO:0031937 16 0.010
regulation of embryonic cell shape GO:0016476 30 0.010
genitalia development GO:0048806 26 0.010
dna alkylation GO:0006305 4 0.010
regulation of stem cell proliferation GO:0072091 40 0.010

Taf4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.020
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
central nervous system disease DOID:331 0 0.012
neurodegenerative disease DOID:1289 0 0.012
parkinson s disease DOID:14330 0 0.012
synucleinopathy DOID:0050890 0 0.012