Drosophila melanogaster

92 known processes

phyl (Dmel_CG10108)

phyllopod

(Aliases: Su(Raf)2C,PHYL,D(DmcycE[JP])2.2,SR2-3,CG10108,Dmel\CG10108,Phyl)

phyl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
r7 cell differentiation GO:0045466 43 0.999
eye photoreceptor cell differentiation GO:0001754 145 0.989
negative regulation of gene expression GO:0010629 387 0.987
compound eye development GO:0048749 307 0.976
negative regulation of nucleic acid templated transcription GO:1903507 240 0.973
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.956
photoreceptor cell differentiation GO:0046530 170 0.953
negative regulation of cellular biosynthetic process GO:0031327 277 0.947
eye morphogenesis GO:0048592 260 0.930
positive regulation of biosynthetic process GO:0009891 316 0.928
regulation of r7 cell differentiation GO:0045676 15 0.899
compound eye morphogenesis GO:0001745 249 0.899
negative regulation of biosynthetic process GO:0009890 277 0.881
compound eye photoreceptor cell differentiation GO:0001751 140 0.858
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.858
regulation of anatomical structure morphogenesis GO:0022603 242 0.822
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.816
negative regulation of transcription dna templated GO:0045892 237 0.793
negative regulation of rna biosynthetic process GO:1902679 240 0.785
sensory organ morphogenesis GO:0090596 260 0.777
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.773
eye development GO:0001654 323 0.731
negative regulation of rna metabolic process GO:0051253 251 0.730
regulation of multicellular organismal development GO:2000026 414 0.657
compound eye photoreceptor fate commitment GO:0001752 36 0.636
regulation of cell development GO:0060284 215 0.614
positive regulation of rna metabolic process GO:0051254 271 0.603
stem cell differentiation GO:0048863 117 0.568
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.561
transcription from rna polymerase ii promoter GO:0006366 368 0.524
compound eye photoreceptor development GO:0042051 78 0.472
compound eye cone cell fate commitment GO:0042676 5 0.455
negative regulation of cellular metabolic process GO:0031324 382 0.440
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.433
cellular response to external stimulus GO:0071496 66 0.416
positive regulation of cellular biosynthetic process GO:0031328 316 0.395
developmental pigmentation GO:0048066 68 0.375
eye photoreceptor cell development GO:0042462 81 0.363
muscle cell differentiation GO:0042692 103 0.345
regulation of cell differentiation GO:0045595 302 0.341
photoreceptor cell fate commitment GO:0046552 41 0.308
muscle organ development GO:0007517 127 0.298
establishment of ommatidial planar polarity GO:0042067 49 0.297
photoreceptor cell development GO:0042461 96 0.296
positive regulation of transcription dna templated GO:0045893 266 0.294
positive regulation of nucleic acid templated transcription GO:1903508 266 0.291
body morphogenesis GO:0010171 2 0.284
chitin based cuticle development GO:0040003 49 0.279
central nervous system development GO:0007417 201 0.276
epithelial cell differentiation GO:0030855 322 0.273
cell fate specification GO:0001708 71 0.273
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.254
cellular response to endogenous stimulus GO:0071495 80 0.252
regulation of organ morphogenesis GO:2000027 78 0.242
compound eye cone cell differentiation GO:0042675 13 0.233
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.229
positive regulation of gene expression GO:0010628 290 0.215
r7 cell development GO:0045467 14 0.211
pigmentation GO:0043473 75 0.203
dendrite morphogenesis GO:0048813 199 0.202
regulation of nervous system development GO:0051960 248 0.201
r7 cell fate commitment GO:0007465 12 0.197
tissue morphogenesis GO:0048729 297 0.194
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.193
response to gravity GO:0009629 26 0.187
ameboidal type cell migration GO:0001667 151 0.179
positive regulation of rna biosynthetic process GO:1902680 266 0.178
positive regulation of developmental process GO:0051094 143 0.164
embryonic organ development GO:0048568 50 0.149
neuron fate commitment GO:0048663 50 0.145
epithelial cell development GO:0002064 274 0.145
myotube cell development GO:0014904 3 0.135
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.133
striated muscle cell development GO:0055002 50 0.132
striated muscle cell differentiation GO:0051146 90 0.131
developmental maturation GO:0021700 172 0.131
negative regulation of developmental process GO:0051093 201 0.129
dendrite development GO:0016358 204 0.126
formation of anatomical boundary GO:0048859 37 0.123
hemocyte differentiation GO:0042386 38 0.120
columnar cuboidal epithelial cell development GO:0002066 249 0.118
cellular amino acid metabolic process GO:0006520 61 0.115
localization of cell GO:0051674 257 0.114
skeletal muscle fiber development GO:0048741 3 0.111
morphogenesis of an epithelium GO:0002009 276 0.106
brain development GO:0007420 120 0.105
hindbrain development GO:0030902 2 0.104
positive regulation of r7 cell differentiation GO:0045678 7 0.099
camera type eye development GO:0043010 4 0.099
spermatogenesis GO:0007283 200 0.097
retina development in camera type eye GO:0060041 4 0.093
regulation of photoreceptor cell differentiation GO:0046532 34 0.093
cellular response to chemical stimulus GO:0070887 199 0.092
eye photoreceptor cell fate commitment GO:0042706 37 0.087
regulation of cell fate specification GO:0042659 27 0.086
regulation of compound eye cone cell fate specification GO:0042682 4 0.085
regionalization GO:0003002 416 0.083
gene silencing GO:0016458 138 0.082
regulation of neuron differentiation GO:0045664 103 0.081
digestive system development GO:0055123 149 0.079
neuron projection guidance GO:0097485 241 0.077
regulation of notch signaling pathway GO:0008593 100 0.075
epithelial cell migration GO:0010631 148 0.073
cellular component assembly involved in morphogenesis GO:0010927 151 0.073
sensory organ precursor cell fate determination GO:0016360 19 0.072
peripheral nervous system development GO:0007422 52 0.072
negative regulation of multicellular organismal process GO:0051241 142 0.071
response to organic substance GO:0010033 284 0.071
organ formation GO:0048645 39 0.070
apoptotic process GO:0006915 159 0.070
stem cell development GO:0048864 79 0.067
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.066
cellular response to organic substance GO:0071310 132 0.066
digestive tract development GO:0048565 149 0.066
stem cell fate commitment GO:0048865 25 0.066
fusion cell fate specification GO:0035156 4 0.064
serotonin metabolic process GO:0042428 2 0.063
protein localization GO:0008104 284 0.063
ovarian follicle cell development GO:0030707 248 0.062
skeletal muscle tissue development GO:0007519 13 0.062
regulation of localization GO:0032879 275 0.060
cell motility GO:0048870 251 0.058
cell migration GO:0016477 238 0.058
organic acid metabolic process GO:0006082 103 0.056
morphogenesis of a polarized epithelium GO:0001738 93 0.055
regulation of gene expression epigenetic GO:0040029 128 0.054
regulation of myotube differentiation GO:0010830 6 0.053
negative regulation of cell differentiation GO:0045596 143 0.052
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.052
cellular response to hormone stimulus GO:0032870 44 0.052
carboxylic acid metabolic process GO:0019752 92 0.051
r1 r6 cell differentiation GO:0048052 4 0.051
regulation of cellular ketone metabolic process GO:0010565 3 0.049
cellular amine metabolic process GO:0044106 12 0.049
ion transport GO:0006811 145 0.048
neurological system process GO:0050877 358 0.048
taxis GO:0042330 304 0.047
positive regulation of retinal cell programmed cell death GO:0046670 9 0.047
establishment of planar polarity GO:0001736 87 0.047
neuron fate specification GO:0048665 12 0.043
protein acetylation GO:0006473 39 0.043
forebrain development GO:0030900 2 0.043
small molecule metabolic process GO:0044281 305 0.043
amine metabolic process GO:0009308 12 0.041
cellular protein modification process GO:0006464 438 0.041
single organism behavior GO:0044708 391 0.040
cuticle development GO:0042335 86 0.040
cellular amide metabolic process GO:0043603 80 0.040
epithelium migration GO:0090132 148 0.040
muscle cell development GO:0055001 50 0.039
single organism biosynthetic process GO:0044711 206 0.039
enzyme linked receptor protein signaling pathway GO:0007167 179 0.039
positive regulation of molecular function GO:0044093 136 0.038
regulation of actin filament based process GO:0032970 42 0.038
positive regulation of cell proliferation GO:0008284 47 0.038
response to endogenous stimulus GO:0009719 119 0.038
chaeta development GO:0022416 97 0.038
formation of organ boundary GO:0010160 30 0.038
regulation of cell morphogenesis GO:0022604 163 0.037
chromatin organization GO:0006325 207 0.037
regulation of epithelial cell proliferation GO:0050678 4 0.037
response to oxygen containing compound GO:1901700 200 0.036
immune system process GO:0002376 347 0.035
intercellular bridge organization GO:0043063 14 0.035
chorion containing eggshell formation GO:0007304 105 0.034
protein transport GO:0015031 155 0.034
establishment of tissue polarity GO:0007164 87 0.034
cell death GO:0008219 279 0.033
equator specification GO:0045317 4 0.033
sensory perception GO:0007600 196 0.033
positive regulation of histone deacetylation GO:0031065 2 0.032
gland development GO:0048732 191 0.032
head development GO:0060322 135 0.032
camera type eye photoreceptor cell differentiation GO:0060219 2 0.032
response to extracellular stimulus GO:0009991 116 0.031
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.031
cell division GO:0051301 248 0.031
urogenital system development GO:0001655 72 0.031
response to lipid GO:0033993 38 0.030
growth GO:0040007 359 0.030
chaeta morphogenesis GO:0008407 42 0.030
axon guidance GO:0007411 233 0.030
regulation of membrane potential GO:0042391 35 0.029
eye antennal disc development GO:0035214 60 0.029
regulation of stem cell proliferation GO:0072091 40 0.028
regulation of cellular amino acid metabolic process GO:0006521 0 0.028
malpighian tubule morphogenesis GO:0007443 44 0.027
sensory organ boundary specification GO:0008052 22 0.027
stem cell maintenance GO:0019827 67 0.027
nephron development GO:0072006 3 0.027
cellular macromolecule localization GO:0070727 220 0.027
establishment of localization in cell GO:0051649 402 0.027
anterior posterior pattern specification GO:0009952 136 0.026
neural retina development GO:0003407 4 0.026
negative regulation of neurogenesis GO:0050768 53 0.026
eggshell chorion assembly GO:0007306 66 0.026
regulation of programmed cell death GO:0043067 152 0.025
epithelial tube morphogenesis GO:0060562 88 0.025
programmed cell death GO:0012501 257 0.024
cell fate determination GO:0001709 91 0.024
oxoacid metabolic process GO:0043436 103 0.024
positive regulation of multicellular organismal process GO:0051240 143 0.024
response to abiotic stimulus GO:0009628 341 0.024
regulation of response to external stimulus GO:0032101 115 0.024
regulation of protein acetylation GO:1901983 7 0.024
muscle cell fate commitment GO:0042693 14 0.024
kidney development GO:0001822 3 0.024
response to glucose GO:0009749 2 0.024
retina morphogenesis in camera type eye GO:0060042 2 0.024
notch signaling pathway GO:0007219 120 0.024
germ line stem cell maintenance GO:0030718 50 0.024
regulation of cell death GO:0010941 173 0.023
gravitaxis GO:0042332 26 0.023
compound eye retinal cell programmed cell death GO:0046667 23 0.023
neuron recognition GO:0008038 101 0.022
muscle structure development GO:0061061 224 0.022
cell cell signaling involved in cell fate commitment GO:0045168 210 0.022
negative regulation of nervous system development GO:0051961 92 0.022
asymmetric cell division GO:0008356 37 0.022
regulation of cellular amine metabolic process GO:0033238 3 0.021
molting cycle GO:0042303 56 0.020
dorsal ventral axis specification GO:0009950 66 0.020
nephrocyte diaphragm assembly GO:0036059 3 0.020
chromatin silencing GO:0006342 76 0.020
appendage development GO:0048736 401 0.020
secretion GO:0046903 109 0.020
response to nutrient levels GO:0031667 114 0.019
regulation of cellular component movement GO:0051270 42 0.019
regulation of reactive oxygen species metabolic process GO:2000377 8 0.019
cell proliferation GO:0008283 299 0.019
muscle system process GO:0003012 21 0.019
epithelial cell proliferation involved in renal tubule morphogenesis GO:2001013 11 0.019
imaginal disc derived wing morphogenesis GO:0007476 337 0.019
gliogenesis GO:0042063 80 0.019
positive regulation of epithelial cell differentiation GO:0030858 1 0.018
spermatid differentiation GO:0048515 114 0.018
divalent metal ion transport GO:0070838 26 0.018
renal system development GO:0072001 72 0.018
regulation of transport GO:0051049 181 0.018
negative regulation of cell death GO:0060548 81 0.018
wing disc morphogenesis GO:0007472 344 0.018
ocellus development GO:0008056 4 0.018
retinal cone cell differentiation GO:0042670 2 0.017
cranial nerve development GO:0021545 1 0.017
eggshell formation GO:0030703 105 0.017
spindle organization GO:0007051 253 0.017
protein localization to nucleus GO:0034504 55 0.017
organelle assembly GO:0070925 198 0.017
actin filament based process GO:0030029 220 0.017
translation GO:0006412 69 0.017
negative regulation of signaling GO:0023057 219 0.017
eye antennal disc morphogenesis GO:0007455 34 0.016
regulation of protein localization to nucleus GO:1900180 29 0.016
cognition GO:0050890 141 0.016
regulation of cell cycle process GO:0010564 181 0.016
muscle tissue development GO:0060537 30 0.016
regulation of heart morphogenesis GO:2000826 3 0.016
tissue migration GO:0090130 155 0.016
circulatory system process GO:0003013 37 0.016
protein acylation GO:0043543 42 0.016
divalent inorganic cation transport GO:0072511 30 0.016
death GO:0016265 284 0.015
positive regulation of cell death GO:0010942 69 0.015
protein catabolic process GO:0030163 101 0.015
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.015
mesenchymal cell differentiation GO:0048762 1 0.015
digestive tract morphogenesis GO:0048546 127 0.015
connective tissue development GO:0061448 3 0.015
adult chitin based cuticle development GO:0008365 2 0.015
muscle tissue morphogenesis GO:0060415 2 0.015
cellular response to organic cyclic compound GO:0071407 32 0.015
tube development GO:0035295 244 0.014
imaginal disc pattern formation GO:0007447 91 0.014
specification of organ identity GO:0010092 3 0.014
negative regulation of catabolic process GO:0009895 36 0.014
morphogenesis of follicular epithelium GO:0016333 36 0.014
peptidyl lysine modification GO:0018205 57 0.014
regulation of cellular localization GO:0060341 136 0.014
positive regulation of notch signaling pathway GO:0045747 34 0.014
mitotic spindle organization GO:0007052 220 0.014
peptidyl amino acid modification GO:0018193 105 0.014
circulatory system development GO:0072359 82 0.013
regulation of locomotion GO:0040012 42 0.013
dorsal ventral pattern formation GO:0009953 133 0.013
macromolecular complex assembly GO:0065003 256 0.013
negative regulation of programmed cell death GO:0043069 72 0.013
mesenchymal cell development GO:0014031 1 0.013
response to hormone GO:0009725 45 0.013
regulation of system process GO:0044057 36 0.013
cellular protein complex assembly GO:0043623 71 0.013
protein modification process GO:0036211 438 0.013
skeletal muscle organ development GO:0060538 48 0.013
cell adhesion GO:0007155 136 0.012
germarium derived egg chamber formation GO:0007293 101 0.012
long term memory GO:0007616 62 0.012
medulla oblongata development GO:0021550 2 0.012
axonogenesis GO:0007409 290 0.012
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.012
response to organic cyclic compound GO:0014070 89 0.012
cellular response to mechanical stimulus GO:0071260 2 0.012
negative regulation of epithelial cell proliferation GO:0050680 4 0.012
positive regulation of photoreceptor cell differentiation GO:0046534 12 0.012
regulation of protein metabolic process GO:0051246 256 0.012
adult chitin based cuticle pattern formation GO:0035018 1 0.012
negative regulation of fusion cell fate specification GO:0035157 2 0.012
negative regulation of cell development GO:0010721 62 0.012
positive regulation of stem cell differentiation GO:2000738 3 0.011
carbohydrate derivative metabolic process GO:1901135 217 0.011
negative regulation of gene expression epigenetic GO:0045814 77 0.011
hematopoietic or lymphoid organ development GO:0048534 57 0.011
establishment of protein localization GO:0045184 163 0.011
regulation of protein localization GO:0032880 76 0.011
post embryonic appendage morphogenesis GO:0035120 385 0.011
stem cell fate specification GO:0048866 2 0.011
lateral inhibition GO:0046331 206 0.011
cell cycle arrest GO:0007050 4 0.011
dephosphorylation GO:0016311 51 0.011
positive regulation of signaling GO:0023056 243 0.011
sex comb development GO:0045498 8 0.011
cellular homeostasis GO:0019725 80 0.011
learning or memory GO:0007611 141 0.011
photoreceptor cell fate specification GO:0043704 9 0.011
positive regulation of protein metabolic process GO:0051247 128 0.010
detection of stimulus GO:0051606 156 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.010
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 20 0.010
regulation of protein deacetylation GO:0090311 2 0.010
regulation of anatomical structure size GO:0090066 163 0.010
spinal cord patterning GO:0021511 1 0.010
aromatic compound catabolic process GO:0019439 166 0.010
striated muscle tissue development GO:0014706 27 0.010
oocyte construction GO:0007308 112 0.010
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 15 0.010
covalent chromatin modification GO:0016569 106 0.010
histone acetylation GO:0016573 38 0.010
chromosome organization GO:0051276 360 0.010

phyl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.075
musculoskeletal system disease DOID:17 0 0.045
muscular disease DOID:0080000 0 0.012
disease of cellular proliferation DOID:14566 0 0.011