Drosophila melanogaster

54 known processes

MED8 (Dmel_CG13867)

Mediator complex subunit 8

(Aliases: dARC32,CG30140,ARC32,CG13867,Arc32,Med8/ARC32,Dmel\CG13867)

MED8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transcription from rna polymerase ii promoter GO:0006366 368 0.578
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.307
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.218
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.192
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.181
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.174
nuclear division GO:0000280 332 0.141
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.138
positive regulation of gene expression GO:0010628 290 0.125
positive regulation of nucleic acid templated transcription GO:1903508 266 0.106
negative regulation of biosynthetic process GO:0009890 277 0.093
positive regulation of transcription dna templated GO:0045893 266 0.084
positive regulation of rna metabolic process GO:0051254 271 0.080
negative regulation of rna biosynthetic process GO:1902679 240 0.080
response to other organism GO:0051707 293 0.077
protein modification process GO:0036211 438 0.071
negative regulation of cellular biosynthetic process GO:0031327 277 0.070
positive regulation of rna biosynthetic process GO:1902680 266 0.069
cellular response to dna damage stimulus GO:0006974 223 0.063
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.057
negative regulation of transcription dna templated GO:0045892 237 0.057
embryo development ending in birth or egg hatching GO:0009792 152 0.055
positive regulation of cellular biosynthetic process GO:0031328 316 0.051
small molecule metabolic process GO:0044281 305 0.047
organelle fission GO:0048285 340 0.047
compound eye development GO:0048749 307 0.042
chromatin modification GO:0016568 147 0.037
negative regulation of cell cycle GO:0045786 116 0.037
mitotic nuclear division GO:0007067 213 0.037
regulation of immune system process GO:0002682 176 0.036
regulation of cell proliferation GO:0042127 163 0.036
positive regulation of macromolecule metabolic process GO:0010604 405 0.035
positive regulation of biosynthetic process GO:0009891 316 0.035
negative regulation of gene expression GO:0010629 387 0.035
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.033
cellular nitrogen compound catabolic process GO:0044270 165 0.033
posttranscriptional regulation of gene expression GO:0010608 145 0.031
regulation of gene expression epigenetic GO:0040029 128 0.030
regulation of cell cycle GO:0051726 291 0.030
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.030
cellular catabolic process GO:0044248 372 0.029
protein complex biogenesis GO:0070271 201 0.028
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.028
cellular protein complex assembly GO:0043623 71 0.028
mitotic g2 m transition checkpoint GO:0044818 70 0.028
catabolic process GO:0009056 409 0.026
cell cell signaling involved in cell fate commitment GO:0045168 210 0.026
negative regulation of developmental process GO:0051093 201 0.026
regulation of multicellular organismal development GO:2000026 414 0.025
regulation of cellular component biogenesis GO:0044087 201 0.025
g2 dna damage checkpoint GO:0031572 69 0.025
negative regulation of mitotic cell cycle GO:0045930 109 0.025
organic substance catabolic process GO:1901575 308 0.024
positive regulation of cell communication GO:0010647 250 0.023
organic acid metabolic process GO:0006082 103 0.022
mitotic cell cycle phase transition GO:0044772 138 0.022
rna catabolic process GO:0006401 37 0.021
mitotic dna damage checkpoint GO:0044773 74 0.021
negative regulation of nucleic acid templated transcription GO:1903507 240 0.021
cellular protein modification process GO:0006464 438 0.020
protein localization GO:0008104 284 0.020
regulation of nervous system development GO:0051960 248 0.020
negative regulation of cellular metabolic process GO:0031324 382 0.020
regulation of cellular amine metabolic process GO:0033238 3 0.019
regulation of multi organism process GO:0043900 131 0.019
cellular macromolecule catabolic process GO:0044265 136 0.019
regulation of cellular protein metabolic process GO:0032268 243 0.019
growth GO:0040007 359 0.019
response to organic substance GO:0010033 284 0.018
single organism cellular localization GO:1902580 180 0.018
oxoacid metabolic process GO:0043436 103 0.017
chromosome segregation GO:0007059 157 0.017
sensory organ morphogenesis GO:0090596 260 0.017
neurological system process GO:0050877 358 0.017
localization of cell GO:0051674 257 0.017
phosphorylation GO:0016310 294 0.017
regulation of mitotic cell cycle GO:0007346 190 0.017
positive regulation of cellular component organization GO:0051130 156 0.016
cell migration GO:0016477 238 0.016
photoreceptor cell differentiation GO:0046530 170 0.016
establishment of localization in cell GO:0051649 402 0.016
positive regulation of signaling GO:0023056 243 0.016
carboxylic acid metabolic process GO:0019752 92 0.016
snrna 3 end processing GO:0034472 14 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
mitotic g2 dna damage checkpoint GO:0007095 69 0.015
positive regulation of signal transduction GO:0009967 223 0.015
protein complex assembly GO:0006461 200 0.014
peptidyl lysine acetylation GO:0018394 39 0.014
rna 3 end processing GO:0031123 45 0.014
eye photoreceptor cell differentiation GO:0001754 145 0.014
rna processing GO:0006396 147 0.014
negative regulation of multicellular organismal process GO:0051241 142 0.013
negative regulation of cell proliferation GO:0008285 69 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
chromosome organization GO:0051276 360 0.013
lateral inhibition GO:0046331 206 0.012
regulation of cell development GO:0060284 215 0.012
macromolecular complex assembly GO:0065003 256 0.012
rna interference GO:0016246 27 0.012
response to biotic stimulus GO:0009607 294 0.012
photoreceptor cell development GO:0042461 96 0.012
peptidyl amino acid modification GO:0018193 105 0.012
covalent chromatin modification GO:0016569 106 0.012
developmental growth GO:0048589 280 0.012
immune response GO:0006955 246 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.011
posttranscriptional gene silencing by rna GO:0035194 45 0.011
appendage development GO:0048736 401 0.011
body morphogenesis GO:0010171 2 0.011
negative regulation of rna metabolic process GO:0051253 251 0.011
dendrite development GO:0016358 204 0.011
regulation of cell cycle process GO:0010564 181 0.011
intracellular transport GO:0046907 228 0.011
mitotic cell cycle checkpoint GO:0007093 88 0.011
negative regulation of nervous system development GO:0051961 92 0.011
eye morphogenesis GO:0048592 260 0.011
eye development GO:0001654 323 0.010
histone modification GO:0016570 106 0.010

MED8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013
central nervous system disease DOID:331 0 0.011