Drosophila melanogaster

216 known processes

Dcr-2 (Dmel_CG6493)

Dicer-2

(Aliases: dicer,Dcr2,dcr2,DCR-2,DCR2,dicer2,Dmel\CG6493,dcr-2,Dicer,cg6493,DICER,CG6493)

Dcr-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
defense response GO:0006952 300 0.991
rhythmic process GO:0048511 106 0.990
circadian rhythm GO:0007623 105 0.987
locomotory behavior GO:0007626 176 0.987
cognition GO:0050890 141 0.983
epithelial cell differentiation GO:0030855 322 0.978
immune system process GO:0002376 347 0.972
single organism behavior GO:0044708 391 0.954
regulation of anatomical structure morphogenesis GO:0022603 242 0.949
actin filament based process GO:0030029 220 0.898
circadian behavior GO:0048512 76 0.897
autophagy GO:0006914 108 0.886
imaginal disc derived wing morphogenesis GO:0007476 337 0.885
epithelial cell development GO:0002064 274 0.873
innate immune response GO:0045087 144 0.868
cellular response to dna damage stimulus GO:0006974 223 0.867
nuclear division GO:0000280 332 0.855
catabolic process GO:0009056 409 0.855
multi organism reproductive behavior GO:0044705 121 0.854
macromolecule catabolic process GO:0009057 161 0.853
muscle structure development GO:0061061 224 0.850
negative regulation of signaling GO:0023057 219 0.844
cellular catabolic process GO:0044248 372 0.840
organelle fission GO:0048285 340 0.830
positive regulation of cellular biosynthetic process GO:0031328 316 0.829
regulation of cytoskeleton organization GO:0051493 89 0.821
regulation of anatomical structure size GO:0090066 163 0.813
synaptic transmission GO:0007268 288 0.810
mitochondrion organization GO:0007005 65 0.806
embryo development ending in birth or egg hatching GO:0009792 152 0.806
response to bacterium GO:0009617 198 0.801
regulation of cellular component size GO:0032535 98 0.799
mating behavior GO:0007617 106 0.796
regionalization GO:0003002 416 0.792
Fly
response to organic cyclic compound GO:0014070 89 0.753
actomyosin structure organization GO:0031032 56 0.753
regulation of catabolic process GO:0009894 170 0.723
immune response GO:0006955 246 0.720
negative regulation of cell communication GO:0010648 223 0.719
learning or memory GO:0007611 141 0.718
cellular component assembly involved in morphogenesis GO:0010927 151 0.709
regulation of organelle organization GO:0033043 196 0.698
muscle cell differentiation GO:0042692 103 0.666
somatic muscle development GO:0007525 66 0.663
regulation of endopeptidase activity GO:0052548 36 0.654
wing disc morphogenesis GO:0007472 344 0.649
muscle cell development GO:0055001 50 0.641
regulation of transport GO:0051049 181 0.630
regulation of gene expression epigenetic GO:0040029 128 0.602
neuromuscular synaptic transmission GO:0007274 67 0.600
protein complex biogenesis GO:0070271 201 0.599
meiotic cell cycle GO:0051321 171 0.598
gene silencing GO:0016458 138 0.593
aging GO:0007568 143 0.588
regulation of cellular catabolic process GO:0031329 157 0.584
regulation of protein metabolic process GO:0051246 256 0.568
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.566
sleep GO:0030431 49 0.565
negative regulation of cellular component organization GO:0051129 108 0.560
secretion by cell GO:0032940 101 0.555
secretion GO:0046903 109 0.553
imaginal disc derived wing hair organization GO:0035317 45 0.534
regulation of cellular localization GO:0060341 136 0.531
response to inorganic substance GO:0010035 44 0.526
regulation of response to stress GO:0080134 200 0.524
negative regulation of response to stimulus GO:0048585 258 0.524
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.520
negative regulation of gene expression GO:0010629 387 0.516
embryonic development via the syncytial blastoderm GO:0001700 148 0.503
response to oxidative stress GO:0006979 86 0.498
meiotic nuclear division GO:0007126 151 0.496
striated muscle cell differentiation GO:0051146 90 0.495
short term memory GO:0007614 19 0.495
regulation of behavior GO:0050795 75 0.494
regulation of catalytic activity GO:0050790 185 0.493
developmental growth GO:0048589 280 0.488
neuron projection guidance GO:0097485 241 0.487
negative regulation of signal transduction GO:0009968 206 0.482
post embryonic appendage morphogenesis GO:0035120 385 0.478
organic substance catabolic process GO:1901575 308 0.478
positive regulation of catabolic process GO:0009896 105 0.476
regulation of cellular component biogenesis GO:0044087 201 0.471
cellular protein modification process GO:0006464 438 0.468
intracellular signal transduction GO:0035556 300 0.459
regulation of defense response to virus by host GO:0050691 10 0.459
positive regulation of cellular catabolic process GO:0031331 95 0.457
epithelial cell migration GO:0010631 148 0.457
immune system development GO:0002520 57 0.448
heterocycle catabolic process GO:0046700 166 0.447
regulation of phosphate metabolic process GO:0019220 210 0.439
hair cell differentiation GO:0035315 47 0.435
ovarian follicle cell development GO:0030707 248 0.435
myofibril assembly GO:0030239 36 0.433
regulation of proteolysis GO:0030162 87 0.432
male mating behavior GO:0060179 70 0.418
negative regulation of programmed cell death GO:0043069 72 0.415
circadian sleep wake cycle sleep GO:0050802 23 0.414
actin cytoskeleton organization GO:0030036 206 0.410
actin filament organization GO:0007015 126 0.406
regulation of phosphorus metabolic process GO:0051174 210 0.404
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.403
dna metabolic process GO:0006259 227 0.399
posttranscriptional regulation of gene expression GO:0010608 145 0.399
response to virus GO:0009615 28 0.380
positive regulation of proteolysis GO:0045862 52 0.380
regulation of secretion by cell GO:1903530 39 0.376
cellular response to starvation GO:0009267 61 0.376
response to organic substance GO:0010033 284 0.373
single organism cellular localization GO:1902580 180 0.371
protein localization GO:0008104 284 0.364
regulation of actin filament length GO:0030832 27 0.361
appendage morphogenesis GO:0035107 397 0.350
regulation of secretion GO:0051046 44 0.348
larval development GO:0002164 104 0.345
axon development GO:0061564 297 0.342
cellular macromolecule localization GO:0070727 220 0.339
dendrite morphogenesis GO:0048813 199 0.337
Fly
heart development GO:0007507 82 0.336
sarcomere organization GO:0045214 26 0.336
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.334
single organism catabolic process GO:0044712 228 0.333
cation transport GO:0006812 110 0.332
establishment of localization in cell GO:0051649 402 0.329
regulation of cell differentiation GO:0045595 302 0.327
regulation of molecular function GO:0065009 217 0.322
regulation of ion transport GO:0043269 39 0.320
cell motility GO:0048870 251 0.320
response to nitrogen compound GO:1901698 90 0.312
response to other organism GO:0051707 293 0.307
wound healing GO:0042060 75 0.307
multicellular organismal reproductive behavior GO:0033057 110 0.304
defense response to other organism GO:0098542 225 0.304
macroautophagy GO:0016236 42 0.302
regulation of protein modification process GO:0031399 112 0.301
regulation of peptidase activity GO:0052547 39 0.298
hematopoietic or lymphoid organ development GO:0048534 57 0.293
chemical homeostasis GO:0048878 92 0.292
carbohydrate metabolic process GO:0005975 82 0.290
morphogenesis of an epithelium GO:0002009 276 0.289
chromosome segregation GO:0007059 157 0.287
carbohydrate derivative metabolic process GO:1901135 217 0.285
response to extracellular stimulus GO:0009991 116 0.284
Fly
ion transmembrane transport GO:0034220 122 0.282
nucleobase containing compound catabolic process GO:0034655 165 0.281
response to nutrient levels GO:0031667 114 0.279
Fly
locomotor rhythm GO:0045475 56 0.278
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.278
defense response to bacterium GO:0042742 178 0.276
protein modification process GO:0036211 438 0.275
regulation of response to external stimulus GO:0032101 115 0.270
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.267
carboxylic acid metabolic process GO:0019752 92 0.266
hemopoiesis GO:0030097 46 0.264
positive regulation of apoptotic signaling pathway GO:2001235 4 0.257
cardiovascular system development GO:0072358 82 0.256
single organism carbohydrate metabolic process GO:0044723 72 0.254
response to oxygen containing compound GO:1901700 200 0.250
chemotaxis GO:0006935 249 0.248
extracellular structure organization GO:0043062 46 0.246
tube development GO:0035295 244 0.236
endocytosis GO:0006897 310 0.235
mitochondrial fission GO:0000266 8 0.233
regulation of dendrite morphogenesis GO:0048814 28 0.231
determination of adult lifespan GO:0008340 137 0.227
cellular protein localization GO:0034613 160 0.226
neuron maturation GO:0042551 31 0.225
imaginal disc derived appendage morphogenesis GO:0035114 395 0.224
reproductive behavior GO:0019098 122 0.224
columnar cuboidal epithelial cell development GO:0002066 249 0.224
meiotic cell cycle process GO:1903046 132 0.223
macromolecular complex assembly GO:0065003 256 0.223
tissue morphogenesis GO:0048729 297 0.223
positive regulation of developmental growth GO:0048639 62 0.222
synapse organization GO:0050808 196 0.219
regulation of cellular protein metabolic process GO:0032268 243 0.217
adult behavior GO:0030534 137 0.216
multicellular organismal aging GO:0010259 140 0.214
protein localization to organelle GO:0033365 82 0.211
muscle organ development GO:0007517 127 0.209
positive regulation of response to stimulus GO:0048584 323 0.206
positive regulation of signaling GO:0023056 243 0.206
protein complex assembly GO:0006461 200 0.205
regulation of actin filament based process GO:0032970 42 0.205
regulation of cell death GO:0010941 173 0.205
regulation of apoptotic process GO:0042981 130 0.203
neurological system process GO:0050877 358 0.202
spermatogenesis GO:0007283 200 0.201
imaginal disc derived appendage development GO:0048737 399 0.201
translation GO:0006412 69 0.200
regulation of autophagy GO:0010506 62 0.200
regulation of synaptic transmission GO:0050804 69 0.197
cellular nitrogen compound catabolic process GO:0044270 165 0.197
positive regulation of cell communication GO:0010647 250 0.197
defense response to gram negative bacterium GO:0050829 94 0.196
ribonucleoside catabolic process GO:0042454 112 0.196
response to metal ion GO:0010038 23 0.189
dephosphorylation GO:0016311 51 0.185
spermatid development GO:0007286 98 0.184
regulation of cysteine type endopeptidase activity GO:2000116 27 0.183
regulation of innate immune response GO:0045088 71 0.180
ribonucleotide catabolic process GO:0009261 109 0.180
cellular protein complex assembly GO:0043623 71 0.179
positive regulation of immune system process GO:0002684 68 0.176
multi organism behavior GO:0051705 175 0.175
response to radiation GO:0009314 155 0.175
negative regulation of catalytic activity GO:0043086 42 0.173
posttranscriptional gene silencing GO:0016441 46 0.170
regulation of defense response GO:0031347 102 0.169
organophosphate metabolic process GO:0019637 195 0.169
nucleoside triphosphate catabolic process GO:0009143 108 0.168
cellular response to organic substance GO:0071310 132 0.165
reactive oxygen species metabolic process GO:0072593 22 0.163
non sensory hair organization GO:0035316 47 0.161
circulatory system development GO:0072359 82 0.161
positive regulation of jun kinase activity GO:0043507 4 0.160
rhythmic behavior GO:0007622 76 0.159
eye development GO:0001654 323 0.158
positive regulation of developmental process GO:0051094 143 0.156
negative regulation of apoptotic process GO:0043066 63 0.155
regulation of intracellular signal transduction GO:1902531 236 0.155
dendrite development GO:0016358 204 0.152
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.150
cellular response to nutrient levels GO:0031669 62 0.148
sperm individualization GO:0007291 48 0.144
homeostatic process GO:0042592 199 0.143
defense response to virus GO:0051607 23 0.141
purine containing compound catabolic process GO:0072523 112 0.140
regulation of neurotransmitter levels GO:0001505 38 0.137
negative regulation of cellular response to oxidative stress GO:1900408 1 0.137
head involution GO:0008258 35 0.136
actin filament polymerization GO:0030041 27 0.132
regulation of synapse structural plasticity GO:0051823 3 0.128
cortical cytoskeleton organization GO:0030865 29 0.128
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.127
positive regulation of protein transport GO:0051222 37 0.126
cellularization GO:0007349 90 0.125
Fly
mating GO:0007618 120 0.125
cation transmembrane transport GO:0098655 88 0.124
purine ribonucleoside metabolic process GO:0046128 127 0.122
immune effector process GO:0002252 98 0.121
apical constriction involved in gastrulation GO:0003384 7 0.121
signal transduction by phosphorylation GO:0023014 107 0.121
epidermal cell differentiation GO:0009913 51 0.119
ion transport GO:0006811 145 0.118
regulation of neuron projection development GO:0010975 69 0.118
apoptotic process GO:0006915 159 0.116
positive regulation of biosynthetic process GO:0009891 316 0.115
syncytium formation GO:0006949 43 0.115
single organism biosynthetic process GO:0044711 206 0.114
response to external biotic stimulus GO:0043207 293 0.113
regulation of developmental growth GO:0048638 174 0.112
establishment of tissue polarity GO:0007164 87 0.111
protein phosphorylation GO:0006468 169 0.111
female meiotic division GO:0007143 70 0.110
positive regulation of hydrolase activity GO:0051345 78 0.109
anatomical structure homeostasis GO:0060249 97 0.105
positive regulation of peptidase activity GO:0010952 29 0.104
myoblast fusion GO:0007520 43 0.104
body morphogenesis GO:0010171 2 0.103
transmembrane transport GO:0055085 139 0.102
posttranscriptional gene silencing by rna GO:0035194 45 0.102
organonitrogen compound metabolic process GO:1901564 318 0.101
protein catabolic process GO:0030163 101 0.099
organic substance transport GO:0071702 257 0.098
positive regulation of multicellular organismal process GO:0051240 143 0.098
regulation of reactive oxygen species metabolic process GO:2000377 8 0.097
regulation of mitochondrion organization GO:0010821 12 0.097
regulation of cell projection organization GO:0031344 92 0.097
regulation of growth GO:0040008 233 0.096
positive regulation of catalytic activity GO:0043085 118 0.095
regulation of hemocyte proliferation GO:0035206 37 0.094
regulation of organ morphogenesis GO:2000027 78 0.092
positive regulation of molecular function GO:0044093 136 0.092
regulation of programmed cell death GO:0043067 152 0.092
transcription from rna polymerase ii promoter GO:0006366 368 0.091
establishment of protein localization to organelle GO:0072594 62 0.090
positive regulation of cellular component biogenesis GO:0044089 80 0.089
negative regulation of cellular metabolic process GO:0031324 382 0.088
response to wounding GO:0009611 94 0.088
male gamete generation GO:0048232 201 0.088
sensory perception GO:0007600 196 0.088
regulation of neuron differentiation GO:0045664 103 0.088
multi multicellular organism process GO:0044706 123 0.088
positive regulation of protein phosphorylation GO:0001934 34 0.087
organelle assembly GO:0070925 198 0.086
negative regulation of molecular function GO:0044092 51 0.086
localization of cell GO:0051674 257 0.085
positive regulation of behavior GO:0048520 19 0.084
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.082
positive regulation of phosphorus metabolic process GO:0010562 139 0.082
regulation of synapse organization GO:0050807 110 0.081
cellular response to oxygen containing compound GO:1901701 79 0.080
cellular amino acid metabolic process GO:0006520 61 0.079
peptidyl tyrosine modification GO:0018212 24 0.079
positive regulation of protein metabolic process GO:0051247 128 0.079
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.079
response to osmotic stress GO:0006970 14 0.078
appendage development GO:0048736 401 0.078
spermatid differentiation GO:0048515 114 0.078
positive regulation of gene expression GO:0010628 290 0.078
nitrogen compound transport GO:0071705 85 0.077
purine ribonucleotide catabolic process GO:0009154 109 0.077
response to biotic stimulus GO:0009607 294 0.077
mitochondrion degradation GO:0000422 8 0.076
mapk cascade GO:0000165 107 0.076
regulation of immune system process GO:0002682 176 0.076
negative regulation of cellular protein metabolic process GO:0032269 85 0.075
positive regulation of growth GO:0045927 75 0.074
ribose phosphate metabolic process GO:0019693 145 0.074
protein transport GO:0015031 155 0.073
positive regulation of immune response GO:0050778 63 0.073
cytokinetic process GO:0032506 27 0.072
response to starvation GO:0042594 97 0.071
Fly
regulation of cell shape GO:0008360 113 0.070
regulation of protein localization to nucleus GO:1900180 29 0.070
positive regulation of cellular protein metabolic process GO:0032270 118 0.070
collateral sprouting GO:0048668 3 0.069
skin development GO:0043588 65 0.069
regulation of synapse structure and activity GO:0050803 128 0.069
cell growth GO:0016049 108 0.068
pigmentation GO:0043473 75 0.068
eye morphogenesis GO:0048592 260 0.068
neuromuscular junction development GO:0007528 149 0.067
cell maturation GO:0048469 144 0.066
purine nucleotide catabolic process GO:0006195 109 0.066
negative regulation of gene expression epigenetic GO:0045814 77 0.065
inositol lipid mediated signaling GO:0048017 4 0.065
eggshell formation GO:0030703 105 0.064
programmed cell death GO:0012501 257 0.063
negative regulation of protein metabolic process GO:0051248 85 0.063
growth GO:0040007 359 0.062
gene silencing by rna GO:0031047 57 0.062
regulation of phosphorylation GO:0042325 147 0.062
cell division GO:0051301 248 0.061
Fly
memory GO:0007613 94 0.061
negative regulation of multicellular organismal process GO:0051241 142 0.061
muscle attachment GO:0016203 36 0.061
lipid metabolic process GO:0006629 121 0.060
head development GO:0060322 135 0.059
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.059
negative regulation of neuron apoptotic process GO:0043524 14 0.057
protein localization to nucleus GO:0034504 55 0.057
learning GO:0007612 75 0.056
cellular macromolecular complex assembly GO:0034622 153 0.056
developmental cell growth GO:0048588 52 0.056
epithelium migration GO:0090132 148 0.056
adult locomotory behavior GO:0008344 76 0.056
ribonucleoside triphosphate catabolic process GO:0009203 108 0.056
regulation of macroautophagy GO:0016241 15 0.055
regulation of nervous system development GO:0051960 248 0.055
chromatin organization GO:0006325 207 0.055
compound eye morphogenesis GO:0001745 249 0.054
regulation of phosphatidylinositol 3 kinase activity GO:0043551 2 0.054
regulation of transferase activity GO:0051338 58 0.054
actin polymerization or depolymerization GO:0008154 31 0.054
mitochondrial fusion GO:0008053 7 0.053
cellular response to metal ion GO:0071248 6 0.053
cellular lipid metabolic process GO:0044255 83 0.052
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.052
protein dephosphorylation GO:0006470 27 0.051
regulation of apoptotic signaling pathway GO:2001233 10 0.051
intracellular transport GO:0046907 228 0.051
cellular response to extracellular stimulus GO:0031668 64 0.050
cellular amine metabolic process GO:0044106 12 0.050
digestive system development GO:0055123 149 0.049
positive regulation of synapse assembly GO:0051965 29 0.049
regulation of actin cytoskeleton organization GO:0032956 42 0.049
aromatic compound catabolic process GO:0019439 166 0.048
positive regulation of cellular component organization GO:0051130 156 0.048
positive regulation of phosphate metabolic process GO:0045937 139 0.048
cellular response to external stimulus GO:0071496 66 0.048
telencephalon development GO:0021537 2 0.047
morphogenesis of a branching structure GO:0001763 45 0.047
behavioral response to ethanol GO:0048149 49 0.047
negative regulation of cell death GO:0060548 81 0.047
central nervous system development GO:0007417 201 0.046
death GO:0016265 284 0.046
oxoacid metabolic process GO:0043436 103 0.046
meiotic cytokinesis GO:0033206 33 0.045
gliogenesis GO:0042063 80 0.045
molting cycle chitin based cuticle GO:0007591 56 0.045
single organism membrane fusion GO:0044801 42 0.045
neuron recognition GO:0008038 101 0.045
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.044
single organism nuclear import GO:1902593 51 0.044
humoral immune response GO:0006959 117 0.044
cytokinetic cell separation GO:0000920 1 0.043
positive regulation of intracellular signal transduction GO:1902533 116 0.042
chromosome organization GO:0051276 360 0.042
regulation of lipid kinase activity GO:0043550 2 0.041
response to light stimulus GO:0009416 124 0.041
camera type eye morphogenesis GO:0048593 2 0.041
regulation of intracellular protein transport GO:0033157 46 0.040
striated muscle cell development GO:0055002 50 0.040
cell migration GO:0016477 238 0.040
purine nucleotide metabolic process GO:0006163 146 0.040
regulation of cell size GO:0008361 63 0.040
activation of protein kinase activity GO:0032147 12 0.039
positive regulation of nitric oxide biosynthetic process GO:0045429 1 0.039
positive regulation of cell death GO:0010942 69 0.038
positive regulation of lipid metabolic process GO:0045834 4 0.038
positive regulation of macromolecule metabolic process GO:0010604 405 0.038
muscle fiber development GO:0048747 12 0.038
activation of innate immune response GO:0002218 4 0.038
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.038
purine ribonucleoside catabolic process GO:0046130 112 0.037
germ line cyst formation GO:0048134 44 0.037
Fly
skeletal muscle organ development GO:0060538 48 0.037
semaphorin plexin signaling pathway GO:0071526 4 0.037
signal release GO:0023061 49 0.036
establishment of protein localization GO:0045184 163 0.036
regulation of metal ion transport GO:0010959 15 0.036
brain development GO:0007420 120 0.036
nucleoside metabolic process GO:0009116 127 0.036
negative regulation of organelle organization GO:0010639 56 0.035
organophosphate catabolic process GO:0046434 112 0.035
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.035
actin mediated cell contraction GO:0070252 21 0.035
regulation of hydrolase activity GO:0051336 97 0.034
positive regulation of transport GO:0051050 92 0.034
axon guidance GO:0007411 233 0.034
vesicle mediated transport GO:0016192 381 0.034
positive regulation of signal transduction GO:0009967 223 0.033
regulation of kinase activity GO:0043549 53 0.032
limb morphogenesis GO:0035108 1 0.032
regulation of cell morphogenesis GO:0022604 163 0.032
phagocytosis engulfment GO:0006911 11 0.032
cell death GO:0008219 279 0.032
purine containing compound metabolic process GO:0072521 155 0.031
regulation of protein transport GO:0051223 57 0.031
response to temperature stimulus GO:0009266 106 0.031
ribonucleotide metabolic process GO:0009259 145 0.031
regulation of cellular response to oxidative stress GO:1900407 4 0.031
regulation of tube size GO:0035150 46 0.031
synaptic transmission dopaminergic GO:0001963 2 0.031
phosphorylation GO:0016310 294 0.031
positive regulation of rna biosynthetic process GO:1902680 266 0.031
actin filament depolymerization GO:0030042 5 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.031
wnt signaling pathway planar cell polarity pathway GO:0060071 6 0.031
negative regulation of neuromuscular synaptic transmission GO:1900074 7 0.030
organic acid metabolic process GO:0006082 103 0.030
cell recognition GO:0008037 102 0.030
regulation of actin polymerization or depolymerization GO:0008064 27 0.029
epidermis development GO:0008544 65 0.029
nucleobase containing small molecule metabolic process GO:0055086 174 0.029
signal transduction in response to dna damage GO:0042770 3 0.029
response to abiotic stimulus GO:0009628 341 0.028
chorion containing eggshell formation GO:0007304 105 0.028
carbohydrate derivative biosynthetic process GO:1901137 85 0.028
protein targeting to nucleus GO:0044744 51 0.028
negative regulation of response to external stimulus GO:0032102 22 0.028
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.028
regulation of stress activated mapk cascade GO:0032872 41 0.028
nucleoside phosphate metabolic process GO:0006753 162 0.028
compound eye development GO:0048749 307 0.028
cell type specific apoptotic process GO:0097285 38 0.027
negative regulation of protein modification process GO:0031400 29 0.027
nucleotide metabolic process GO:0009117 161 0.027
regulation of protein kinase activity GO:0045859 51 0.027
regulation of neurogenesis GO:0050767 158 0.027
negative regulation of growth GO:0045926 84 0.027
cellular response to chemical stimulus GO:0070887 199 0.027
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.027
positive regulation of secretion by cell GO:1903532 20 0.026
organic cyclic compound catabolic process GO:1901361 168 0.026
regulation of multicellular organismal development GO:2000026 414 0.026
stress activated mapk cascade GO:0051403 52 0.026
sperm axoneme assembly GO:0007288 13 0.026
male meiosis GO:0007140 52 0.026
photoreceptor cell differentiation GO:0046530 170 0.026
biological adhesion GO:0022610 138 0.025
negative regulation of kinase activity GO:0033673 16 0.025
lipid biosynthetic process GO:0008610 46 0.025
actin filament bundle organization GO:0061572 28 0.025
divalent inorganic cation homeostasis GO:0072507 29 0.025
nucleocytoplasmic transport GO:0006913 72 0.025
regulation of establishment of protein localization GO:0070201 61 0.025
nucleoside phosphate catabolic process GO:1901292 110 0.025
segmentation GO:0035282 207 0.025
Fly
cellular response to organic cyclic compound GO:0071407 32 0.025
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.025
response to endogenous stimulus GO:0009719 119 0.024
single organism intracellular transport GO:1902582 207 0.024
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.024
sperm mitochondrion organization GO:0030382 7 0.024
peripheral nervous system development GO:0007422 52 0.024

Dcr-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.208
cardiovascular system disease DOID:1287 0 0.093
disease of metabolism DOID:0014667 0 0.045
cancer DOID:162 0 0.038
disease of cellular proliferation DOID:14566 0 0.038
parkinson s disease DOID:14330 0 0.025
synucleinopathy DOID:0050890 0 0.025
central nervous system disease DOID:331 0 0.025
neurodegenerative disease DOID:1289 0 0.025
nervous system disease DOID:863 0 0.025