Drosophila melanogaster

48 known processes

M6 (Dmel_CG7540)

CG7540 gene product from transcript CG7540-RA

(Aliases: CG7540,dM6a,Dmel\CG7540)

M6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
determination of adult lifespan GO:0008340 137 0.573
programmed cell death GO:0012501 257 0.495
multicellular organismal aging GO:0010259 140 0.479
regulation of tube architecture open tracheal system GO:0035152 68 0.421
regulation of cell differentiation GO:0045595 302 0.406
response to radiation GO:0009314 155 0.397
negative regulation of cell communication GO:0010648 223 0.369
negative regulation of cell differentiation GO:0045596 143 0.367
homeostatic process GO:0042592 199 0.296
post embryonic appendage morphogenesis GO:0035120 385 0.278
defense response GO:0006952 300 0.263
regulation of multi organism process GO:0043900 131 0.250
response to abiotic stimulus GO:0009628 341 0.249
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.247
single organism biosynthetic process GO:0044711 206 0.247
regulation of cellular response to stress GO:0080135 89 0.247
regulation of neurogenesis GO:0050767 158 0.246
enzyme linked receptor protein signaling pathway GO:0007167 179 0.244
notch signaling pathway GO:0007219 120 0.241
dna integrity checkpoint GO:0031570 81 0.232
establishment of vesicle localization GO:0051650 51 0.222
synaptic transmission GO:0007268 288 0.219
dna damage checkpoint GO:0000077 78 0.218
wing disc morphogenesis GO:0007472 344 0.208
imaginal disc derived appendage development GO:0048737 399 0.208
establishment of localization in cell GO:0051649 402 0.207
appendage morphogenesis GO:0035107 397 0.206
establishment of organelle localization GO:0051656 122 0.188
appendage development GO:0048736 401 0.182
regulation of intracellular signal transduction GO:1902531 236 0.182
response to external biotic stimulus GO:0043207 293 0.179
negative regulation of developmental process GO:0051093 201 0.175
positive regulation of response to stimulus GO:0048584 323 0.165
response to light stimulus GO:0009416 124 0.154
death GO:0016265 284 0.149
intrinsic apoptotic signaling pathway GO:0097193 16 0.149
imaginal disc derived appendage morphogenesis GO:0035114 395 0.147
epithelial cell development GO:0002064 274 0.146
septate junction assembly GO:0019991 26 0.141
regulation of growth GO:0040008 233 0.132
response to other organism GO:0051707 293 0.132
developmental maturation GO:0021700 172 0.130
regulation of mitotic cell cycle GO:0007346 190 0.129
lipid localization GO:0010876 54 0.127
establishment of synaptic vesicle localization GO:0097480 50 0.125
cardiovascular system development GO:0072358 82 0.120
regulation of cell cycle process GO:0010564 181 0.117
immune system process GO:0002376 347 0.116
regulation of response to stress GO:0080134 200 0.113
lipid storage GO:0019915 38 0.110
tube morphogenesis GO:0035239 191 0.109
vesicle mediated transport GO:0016192 381 0.109
developmental growth GO:0048589 280 0.109
vesicle localization GO:0051648 55 0.107
mating behavior GO:0007617 106 0.106
cellular component assembly involved in morphogenesis GO:0010927 151 0.106
mitotic dna integrity checkpoint GO:0044774 75 0.105
regulation of immune system process GO:0002682 176 0.103
cell cycle checkpoint GO:0000075 95 0.101
epithelial cell differentiation GO:0030855 322 0.100
embryonic morphogenesis GO:0048598 206 0.098
mitotic dna damage checkpoint GO:0044773 74 0.094
ion transport GO:0006811 145 0.092
positive regulation of macromolecule metabolic process GO:0010604 405 0.089
organelle localization GO:0051640 148 0.086
aging GO:0007568 143 0.086
secretion GO:0046903 109 0.085
digestive tract morphogenesis GO:0048546 127 0.084
endocytosis GO:0006897 310 0.083
g2 dna damage checkpoint GO:0031572 69 0.083
neuron projection guidance GO:0097485 241 0.082
proteolysis GO:0006508 192 0.082
immune effector process GO:0002252 98 0.082
apical junction assembly GO:0043297 32 0.077
cell cell junction assembly GO:0007043 38 0.076
growth GO:0040007 359 0.075
eye development GO:0001654 323 0.073
response to oxidative stress GO:0006979 86 0.072
cell cell junction organization GO:0045216 55 0.072
negative regulation of signaling GO:0023057 219 0.071
maintenance of location GO:0051235 73 0.069
ribonucleotide metabolic process GO:0009259 145 0.068
synapse assembly GO:0007416 143 0.067
cell junction assembly GO:0034329 42 0.067
heart development GO:0007507 82 0.066
regulation of localization GO:0032879 275 0.065
gland development GO:0048732 191 0.065
cell death GO:0008219 279 0.064
positive regulation of signal transduction GO:0009967 223 0.063
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.058
larval development GO:0002164 104 0.058
regulation of programmed cell death GO:0043067 152 0.058
positive regulation of cell migration GO:0030335 2 0.057
ethanolamine containing compound metabolic process GO:0042439 4 0.057
defense response to other organism GO:0098542 225 0.055
anatomical structure homeostasis GO:0060249 97 0.055
localization of cell GO:0051674 257 0.054
immune system development GO:0002520 57 0.052
protein phosphorylation GO:0006468 169 0.052
regulation of cytoskeleton organization GO:0051493 89 0.052
regulation of protein metabolic process GO:0051246 256 0.052
forebrain development GO:0030900 2 0.051
regulation of notch signaling pathway GO:0008593 100 0.051
regulation of cell cycle phase transition GO:1901987 130 0.051
reproductive behavior GO:0019098 122 0.051
single organism behavior GO:0044708 391 0.050
cellular macromolecule localization GO:0070727 220 0.050
negative regulation of multicellular organismal process GO:0051241 142 0.049
protein modification process GO:0036211 438 0.049
negative regulation of cellular metabolic process GO:0031324 382 0.049
regeneration GO:0031099 16 0.049
positive regulation of cell cycle GO:0045787 43 0.047
cellular lipid metabolic process GO:0044255 83 0.047
mitotic cell cycle checkpoint GO:0007093 88 0.047
regulation of immune effector process GO:0002697 52 0.047
regulation of synapse structure and activity GO:0050803 128 0.047
respiratory system development GO:0060541 213 0.046
cognition GO:0050890 141 0.046
synapse organization GO:0050808 196 0.046
regulation of tube length open tracheal system GO:0035159 24 0.044
regulation of transport GO:0051049 181 0.044
peptidyl amino acid modification GO:0018193 105 0.044
autophagic vacuole assembly GO:0000045 2 0.044
regulation of multicellular organismal development GO:2000026 414 0.044
apoptotic process GO:0006915 159 0.043
carbohydrate derivative biosynthetic process GO:1901137 85 0.042
regulation of molecular function GO:0065009 217 0.042
synaptic vesicle localization GO:0097479 53 0.041
regulation of organelle organization GO:0033043 196 0.040
cellular amino acid metabolic process GO:0006520 61 0.040
detection of light stimulus GO:0009583 58 0.039
cell junction organization GO:0034330 57 0.039
response to wounding GO:0009611 94 0.039
cell maturation GO:0048469 144 0.039
regulation of phosphorylation GO:0042325 147 0.039
cellular protein modification process GO:0006464 438 0.039
positive regulation of signaling GO:0023056 243 0.038
regulation of vesicle mediated transport GO:0060627 59 0.038
negative regulation of cell death GO:0060548 81 0.037
regulation of catalytic activity GO:0050790 185 0.037
biological adhesion GO:0022610 138 0.037
protein transport GO:0015031 155 0.037
apoptotic signaling pathway GO:0097190 27 0.037
lipid metabolic process GO:0006629 121 0.036
positive regulation of protein metabolic process GO:0051247 128 0.036
positive regulation of cellular amine metabolic process GO:0033240 0 0.036
developmental programmed cell death GO:0010623 138 0.036
regulation of peptidase activity GO:0052547 39 0.034
taxis GO:0042330 304 0.034
hemopoiesis GO:0030097 46 0.034
regulation of cellular protein metabolic process GO:0032268 243 0.034
negative regulation of response to stimulus GO:0048585 258 0.034
response to axon injury GO:0048678 12 0.033
regulation of cellular amino acid metabolic process GO:0006521 0 0.033
amine metabolic process GO:0009308 12 0.032
regulation of cell development GO:0060284 215 0.031
positive regulation of cell cycle process GO:0090068 28 0.030
oxoacid metabolic process GO:0043436 103 0.030
establishment of blood brain barrier GO:0060856 16 0.030
carbohydrate derivative metabolic process GO:1901135 217 0.030
stress activated protein kinase signaling cascade GO:0031098 55 0.030
synaptic vesicle transport GO:0048489 50 0.030
regulation of proteolysis GO:0030162 87 0.030
peptidyl lysine acetylation GO:0018394 39 0.029
negative regulation of signal transduction GO:0009968 206 0.029
tube development GO:0035295 244 0.028
dna metabolic process GO:0006259 227 0.028
positive regulation of apoptotic signaling pathway GO:2001235 4 0.028
membrane organization GO:0061024 112 0.028
camera type eye morphogenesis GO:0048593 2 0.028
regulation of phosphate metabolic process GO:0019220 210 0.027
mitotic cell cycle phase transition GO:0044772 138 0.027
regulation of actin filament based process GO:0032970 42 0.027
chemotaxis GO:0006935 249 0.027
positive regulation of molecular function GO:0044093 136 0.027
single organism intracellular transport GO:1902582 207 0.027
positive regulation of cellular biosynthetic process GO:0031328 316 0.027
cellular amine metabolic process GO:0044106 12 0.026
embryo development ending in birth or egg hatching GO:0009792 152 0.026
myotube cell development GO:0014904 3 0.026
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.025
regulation of neurotransmitter levels GO:0001505 38 0.025
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.025
positive regulation of protein phosphorylation GO:0001934 34 0.024
ion homeostasis GO:0050801 55 0.024
regulation of cellular ketone metabolic process GO:0010565 3 0.024
negative regulation of cellular component organization GO:0051129 108 0.024
organic substance transport GO:0071702 257 0.024
regulation of anatomical structure morphogenesis GO:0022603 242 0.023
organic acid metabolic process GO:0006082 103 0.023
transcription from rna polymerase ii promoter GO:0006366 368 0.023
multi organism reproductive behavior GO:0044705 121 0.023
dendrite development GO:0016358 204 0.022
dendrite morphogenesis GO:0048813 199 0.022
response to virus GO:0009615 28 0.022
regulation of anatomical structure size GO:0090066 163 0.022
actin filament based movement GO:0030048 26 0.022
synaptic growth at neuromuscular junction GO:0051124 119 0.022
regulation of protein import into nucleus GO:0042306 28 0.022
establishment of protein localization GO:0045184 163 0.022
negative regulation of immune system process GO:0002683 50 0.022
response to lipopolysaccharide GO:0032496 4 0.021
positive regulation of phosphorylation GO:0042327 87 0.021
central nervous system development GO:0007417 201 0.021
negative regulation of programmed cell death GO:0043069 72 0.021
positive regulation of transport GO:0051050 92 0.021
axon development GO:0061564 297 0.021
protein localization GO:0008104 284 0.021
regulation of response to external stimulus GO:0032101 115 0.021
regulation of mitotic cell cycle phase transition GO:1901990 130 0.020
multi organism behavior GO:0051705 175 0.020
spermatogenesis GO:0007283 200 0.020
eye morphogenesis GO:0048592 260 0.020
learning or memory GO:0007611 141 0.020
tissue homeostasis GO:0001894 36 0.020
positive regulation of multicellular organismal process GO:0051240 143 0.020
extrinsic apoptotic signaling pathway GO:0097191 1 0.020
protein complex assembly GO:0006461 200 0.020
regulation of cell cycle GO:0051726 291 0.020
organelle fission GO:0048285 340 0.020
regulation of intracellular transport GO:0032386 64 0.019
regulation of cell morphogenesis GO:0022604 163 0.019
single organism membrane organization GO:0044802 93 0.019
regulation of neuron differentiation GO:0045664 103 0.019
regulation of cell size GO:0008361 63 0.019
negative regulation of nervous system development GO:0051961 92 0.019
multicellular organismal reproductive behavior GO:0033057 110 0.019
regulation of cellular amine metabolic process GO:0033238 3 0.019
protein catabolic process GO:0030163 101 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.019
carboxylic acid metabolic process GO:0019752 92 0.019
exocytosis GO:0006887 28 0.018
cuticle pigmentation GO:0048067 22 0.018
cellular ketone metabolic process GO:0042180 24 0.018
positive regulation of phosphate metabolic process GO:0045937 139 0.018
columnar cuboidal epithelial cell development GO:0002066 249 0.018
skeletal muscle fiber development GO:0048741 3 0.018
positive regulation of catalytic activity GO:0043085 118 0.018
cation transport GO:0006812 110 0.018
exocrine system development GO:0035272 162 0.018
muscle attachment GO:0016203 36 0.018
acetylcholine catabolic process GO:0006581 1 0.018
establishment of blood nerve barrier GO:0008065 2 0.018
cell migration GO:0016477 238 0.018
regulation of intracellular protein transport GO:0033157 46 0.018
macromolecule catabolic process GO:0009057 161 0.018
purine ribonucleotide metabolic process GO:0009150 145 0.017
cellular response to dna damage stimulus GO:0006974 223 0.017
paracrine signaling GO:0038001 7 0.017
negative regulation of apoptotic process GO:0043066 63 0.017
camera type eye development GO:0043010 4 0.017
axon guidance GO:0007411 233 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
cell growth GO:0016049 108 0.017
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 15 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
organelle assembly GO:0070925 198 0.017
regulation of defense response GO:0031347 102 0.016
chromosome segregation GO:0007059 157 0.016
negative regulation of cell development GO:0010721 62 0.016
cell cycle arrest GO:0007050 4 0.016
positive regulation of immune system process GO:0002684 68 0.016
regulation of apoptotic process GO:0042981 130 0.016
small molecule metabolic process GO:0044281 305 0.016
response to bacterium GO:0009617 198 0.016
fatty acid metabolic process GO:0006631 20 0.016
nephron morphogenesis GO:0072028 3 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.016
cell adhesion GO:0007155 136 0.015
chemical homeostasis GO:0048878 92 0.015
secretion by cell GO:0032940 101 0.015
negative regulation of multi organism process GO:0043901 29 0.015
regulation of lipid storage GO:0010883 22 0.015
regulation of protein transport GO:0051223 57 0.015
telencephalon development GO:0021537 2 0.015
response to starvation GO:0042594 97 0.015
cell division GO:0051301 248 0.015
nitrogen compound transport GO:0071705 85 0.015
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 4 0.015
actin mediated cell contraction GO:0070252 21 0.015
negative regulation of protein metabolic process GO:0051248 85 0.015
posttranscriptional regulation of gene expression GO:0010608 145 0.015
regulation of stress activated mapk cascade GO:0032872 41 0.014
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.014
segmentation GO:0035282 207 0.014
lysosome organization GO:0007040 4 0.014
detection of abiotic stimulus GO:0009582 66 0.014
regulation of protein phosphorylation GO:0001932 64 0.014
compound eye retinal cell programmed cell death GO:0046667 23 0.014
actin filament capping GO:0051693 2 0.014
positive regulation of cell size GO:0045793 21 0.014
fertilization GO:0009566 26 0.014
negative regulation of cell cycle phase transition GO:1901988 103 0.014
necrotic cell death GO:0070265 1 0.013
positive regulation of cell motility GO:2000147 3 0.013
single organism cell adhesion GO:0098602 47 0.013
neural retina development GO:0003407 4 0.013
positive regulation of cell communication GO:0010647 250 0.013
morphogenesis of embryonic epithelium GO:0016331 94 0.013
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.013
cation homeostasis GO:0055080 51 0.013
cilium organization GO:0044782 41 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
nucleotide metabolic process GO:0009117 161 0.013
regulation of reproductive process GO:2000241 54 0.013
response to biotic stimulus GO:0009607 294 0.013
response to organic substance GO:0010033 284 0.013
regulation of cell proliferation GO:0042127 163 0.013
regulation of protein kinase activity GO:0045859 51 0.013
positive regulation of apoptotic process GO:0043065 47 0.013
organonitrogen compound metabolic process GO:1901564 318 0.013
imaginal disc derived leg segmentation GO:0036011 26 0.013
intracellular transport GO:0046907 228 0.013
regulation of cellular localization GO:0060341 136 0.013
regulation of protein modification process GO:0031399 112 0.013
ameboidal type cell migration GO:0001667 151 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
regulation of nervous system development GO:0051960 248 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 16 0.012
response to oxygen containing compound GO:1901700 200 0.012
regulation of developmental growth GO:0048638 174 0.012
imaginal disc derived wing morphogenesis GO:0007476 337 0.012
nucleoside triphosphate metabolic process GO:0009141 120 0.012
regulation of response to biotic stimulus GO:0002831 63 0.012
organic substance catabolic process GO:1901575 308 0.012
single organism cellular localization GO:1902580 180 0.012
regulation of secretion GO:0051046 44 0.012
mitotic nuclear division GO:0007067 213 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
gastrulation GO:0007369 70 0.012
positive regulation of protein localization to nucleus GO:1900182 21 0.012
muscle organ development GO:0007517 127 0.012
vesicle organization GO:0016050 44 0.012
cellular protein localization GO:0034613 160 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.012
macromolecular complex assembly GO:0065003 256 0.012
wound healing GO:0042060 75 0.011
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.011
tissue morphogenesis GO:0048729 297 0.011
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.011
interspecies interaction between organisms GO:0044419 16 0.011
cilium assembly GO:0042384 38 0.011
regionalization GO:0003002 416 0.011
imaginal disc fusion GO:0046528 19 0.011
embryonic organ development GO:0048568 50 0.011
cell cycle phase transition GO:0044770 140 0.011
peptidyl tyrosine phosphorylation GO:0018108 24 0.011
limb morphogenesis GO:0035108 1 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
microtubule bundle formation GO:0001578 27 0.011
positive regulation of notch signaling pathway GO:0045747 34 0.011
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.011
regulation of microtubule cytoskeleton organization GO:0070507 41 0.011
positive regulation of cell differentiation GO:0045597 64 0.011
regulation of microtubule based process GO:0032886 49 0.011
neurotransmitter transport GO:0006836 37 0.011
embryonic hemopoiesis GO:0035162 26 0.011
detection of external stimulus GO:0009581 66 0.011
immune response regulating signaling pathway GO:0002764 2 0.011
positive regulation of neurogenesis GO:0050769 41 0.010
cell aging GO:0007569 2 0.010
organophosphate catabolic process GO:0046434 112 0.010
neuron maturation GO:0042551 31 0.010
regulation of cell death GO:0010941 173 0.010
heart morphogenesis GO:0003007 32 0.010
connective tissue development GO:0061448 3 0.010
regulation of dendrite morphogenesis GO:0048814 28 0.010
negative regulation of organelle organization GO:0010639 56 0.010

M6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
musculoskeletal system disease DOID:17 0 0.024
nervous system disease DOID:863 0 0.016
bone disease DOID:0080001 0 0.012
connective tissue disease DOID:65 0 0.012
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.011