Drosophila melanogaster

48 known processes

Manf (Dmel_CG7013)

Mesencephalic astrocyte-derived neurotrophic factor

(Aliases: CG7013,anon-EST:ParkEST188,ARP-like,Dmel\CG7013,DmMANF)

Manf biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of localization in cell GO:0051649 402 0.357
intracellular transport GO:0046907 228 0.211
protein localization GO:0008104 284 0.177
multi multicellular organism process GO:0044706 123 0.171
golgi vesicle transport GO:0048193 27 0.158
single organism behavior GO:0044708 391 0.151
reproductive behavior GO:0019098 122 0.145
regulation of reproductive process GO:2000241 54 0.135
single organism intracellular transport GO:1902582 207 0.124
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.119
cellular macromolecule localization GO:0070727 220 0.113
oocyte development GO:0048599 124 0.098
oocyte differentiation GO:0009994 145 0.096
oocyte axis specification GO:0007309 108 0.091
regulation of post mating oviposition GO:0048042 10 0.089
dorsal ventral axis specification GO:0009950 66 0.086
regulation of localization GO:0032879 275 0.085
embryo development ending in birth or egg hatching GO:0009792 152 0.085
oocyte dorsal ventral axis specification GO:0007310 34 0.083
response to organic substance GO:0010033 284 0.081
organic substance transport GO:0071702 257 0.077
autophagy GO:0006914 108 0.075
positive regulation of cell communication GO:0010647 250 0.075
intracellular signal transduction GO:0035556 300 0.074
embryonic development via the syncytial blastoderm GO:0001700 148 0.073
positive regulation of response to stimulus GO:0048584 323 0.068
regionalization GO:0003002 416 0.061
dorsal ventral pattern formation GO:0009953 133 0.061
photoreceptor cell development GO:0042461 96 0.060
multicellular organismal reproductive behavior GO:0033057 110 0.057
protein transport GO:0015031 155 0.056
maintenance of location GO:0051235 73 0.056
post mating oviposition GO:0060403 10 0.054
multi organism reproductive behavior GO:0044705 121 0.052
secretion GO:0046903 109 0.052
regulation of behavior GO:0050795 75 0.052
localization of cell GO:0051674 257 0.049
catabolic process GO:0009056 409 0.049
response to unfolded protein GO:0006986 9 0.048
larval development GO:0002164 104 0.047
rna localization GO:0006403 115 0.047
regulation of vesicle mediated transport GO:0060627 59 0.046
axis specification GO:0009798 167 0.046
developmental maturation GO:0021700 172 0.046
regulation of oviposition GO:0046662 14 0.045
endocytosis GO:0006897 310 0.044
positive regulation of biosynthetic process GO:0009891 316 0.043
axonogenesis GO:0007409 290 0.041
positive regulation of transcription dna templated GO:0045893 266 0.041
cell death GO:0008219 279 0.041
multi organism behavior GO:0051705 175 0.039
spindle organization GO:0007051 253 0.038
regulation of transport GO:0051049 181 0.038
cytoplasmic transport GO:0016482 130 0.037
establishment of protein localization GO:0045184 163 0.037
mitotic spindle organization GO:0007052 220 0.037
camera type eye development GO:0043010 4 0.036
cellular catabolic process GO:0044248 372 0.036
lipid storage GO:0019915 38 0.036
positive regulation of cellular biosynthetic process GO:0031328 316 0.036
eye development GO:0001654 323 0.036
molting cycle chitin based cuticle GO:0007591 56 0.035
regulation of multi organism process GO:0043900 131 0.035
vesicle mediated transport GO:0016192 381 0.033
protein adp ribosylation GO:0006471 4 0.032
phagocytosis GO:0006909 215 0.032
oocyte construction GO:0007308 112 0.032
post mating behavior GO:0045297 11 0.032
cell maturation GO:0048469 144 0.031
single organism cellular localization GO:1902580 180 0.031
adult behavior GO:0030534 137 0.029
positive regulation of signaling GO:0023056 243 0.029
taxis GO:0042330 304 0.029
positive regulation of rna metabolic process GO:0051254 271 0.029
tissue morphogenesis GO:0048729 297 0.028
regulation of endocytosis GO:0030100 37 0.028
organelle localization GO:0051640 148 0.028
positive regulation of nucleic acid templated transcription GO:1903508 266 0.026
secretion by cell GO:0032940 101 0.025
carbohydrate derivative biosynthetic process GO:1901137 85 0.025
response to oxygen containing compound GO:1901700 200 0.025
negative regulation of autophagy GO:0010507 16 0.025
carbohydrate derivative metabolic process GO:1901135 217 0.025
regulation of protein secretion GO:0050708 13 0.024
spermatogenesis GO:0007283 200 0.024
male gamete generation GO:0048232 201 0.024
regulation of wnt protein secretion GO:0061356 5 0.023
positive regulation of signal transduction GO:0009967 223 0.023
meiotic cell cycle process GO:1903046 132 0.022
nuclear division GO:0000280 332 0.022
instar larval development GO:0002168 55 0.022
cellular protein localization GO:0034613 160 0.021
regulation of multicellular organismal development GO:2000026 414 0.021
negative regulation of cellular metabolic process GO:0031324 382 0.021
positive regulation of rna biosynthetic process GO:1902680 266 0.021
positive regulation of gene expression GO:0010628 290 0.021
regulation of cell death GO:0010941 173 0.021
protein complex assembly GO:0006461 200 0.020
response to abiotic stimulus GO:0009628 341 0.020
transcription from rna polymerase ii promoter GO:0006366 368 0.020
maternal specification of dorsal ventral axis oocyte germ line encoded GO:0007311 4 0.020
establishment of organelle localization GO:0051656 122 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.019
death GO:0016265 284 0.019
growth GO:0040007 359 0.018
positive regulation of transport GO:0051050 92 0.018
regulation of establishment of protein localization GO:0070201 61 0.018
regulation of cell differentiation GO:0045595 302 0.017
wnt protein secretion GO:0061355 5 0.017
protein secretion GO:0009306 45 0.017
stem cell differentiation GO:0048863 117 0.017
regulation of secretion by cell GO:1903530 39 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.017
protein complex biogenesis GO:0070271 201 0.016
positive regulation of cellular component organization GO:0051130 156 0.016
cellular macromolecule catabolic process GO:0044265 136 0.016
regulation of anatomical structure morphogenesis GO:0022603 242 0.016
intracellular protein transport GO:0006886 104 0.016
camera type eye morphogenesis GO:0048593 2 0.016
regulation of secretion GO:0051046 44 0.015
regulation of synapse organization GO:0050807 110 0.015
protein processing GO:0016485 68 0.015
response to temperature stimulus GO:0009266 106 0.015
cellular protein modification process GO:0006464 438 0.015
membrane budding GO:0006900 4 0.015
protein maturation GO:0051604 71 0.014
single organism carbohydrate metabolic process GO:0044723 72 0.014
organonitrogen compound metabolic process GO:1901564 318 0.014
cellular response to chemical stimulus GO:0070887 199 0.014
regulation of catalytic activity GO:0050790 185 0.014
protein import GO:0017038 55 0.014
chemotaxis GO:0006935 249 0.014
regulation of protein localization GO:0032880 76 0.014
golgi organization GO:0007030 66 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.013
regulation of cell substrate adhesion GO:0010810 2 0.013
cellular response to starvation GO:0009267 61 0.012
regulation of intracellular signal transduction GO:1902531 236 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
organic substance catabolic process GO:1901575 308 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
ras protein signal transduction GO:0007265 88 0.012
lipid localization GO:0010876 54 0.011
body morphogenesis GO:0010171 2 0.011
regulation of synapse structure and activity GO:0050803 128 0.011
chromosome segregation GO:0007059 157 0.011
smad protein import into nucleus GO:0007184 11 0.011
inorganic ion transmembrane transport GO:0098660 73 0.011
cation transmembrane transport GO:0098655 88 0.011
response to decreased oxygen levels GO:0036293 58 0.010
er associated ubiquitin dependent protein catabolic process GO:0030433 3 0.010
eye photoreceptor cell development GO:0042462 81 0.010
meiotic cell cycle GO:0051321 171 0.010
regulation of cell morphogenesis GO:0022604 163 0.010
carbohydrate metabolic process GO:0005975 82 0.010

Manf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 0 0.016
disease of anatomical entity DOID:7 0 0.016
muscular disease DOID:0080000 0 0.016
muscle tissue disease DOID:66 0 0.011