Drosophila melanogaster

34 known processes

Pros29 (Dmel_CG9327)

Proteasome 29kD subunit

(Aliases: pros29,Prosalpha3,alpha3_dm,PSB3_DROME,CG9327,Pros20S-alpha3,PROS-29,Dmel\CG9327)

Pros29 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic spindle elongation GO:0000022 81 0.972
ubiquitin dependent protein catabolic process GO:0006511 78 0.965
modification dependent macromolecule catabolic process GO:0043632 79 0.958
cellular response to dna damage stimulus GO:0006974 223 0.953
proteolysis GO:0006508 192 0.869
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.816
modification dependent protein catabolic process GO:0019941 78 0.780
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.752
cellular protein catabolic process GO:0044257 83 0.737
cellular catabolic process GO:0044248 372 0.598
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.547
protein catabolic process GO:0030163 101 0.474
proteasomal protein catabolic process GO:0010498 59 0.466
programmed cell death GO:0012501 257 0.455
death GO:0016265 284 0.437
macromolecule catabolic process GO:0009057 161 0.390
organelle fission GO:0048285 340 0.320
catabolic process GO:0009056 409 0.318
cell proliferation GO:0008283 299 0.285
cellular macromolecule catabolic process GO:0044265 136 0.258
mitotic cell cycle phase transition GO:0044772 138 0.248
apoptotic process GO:0006915 159 0.209
larval development GO:0002164 104 0.185
macromolecular complex assembly GO:0065003 256 0.175
protein dna complex subunit organization GO:0071824 86 0.171
mitotic g2 dna damage checkpoint GO:0007095 69 0.167
spindle organization GO:0007051 253 0.167
cell death GO:0008219 279 0.156
organic substance catabolic process GO:1901575 308 0.140
transcription from rna polymerase ii promoter GO:0006366 368 0.107
cellular macromolecular complex assembly GO:0034622 153 0.104
centrosome organization GO:0051297 163 0.095
protein complex biogenesis GO:0070271 201 0.093
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.091
embryo development ending in birth or egg hatching GO:0009792 152 0.090
protein localization GO:0008104 284 0.077
dna metabolic process GO:0006259 227 0.074
male meiosis GO:0007140 52 0.073
positive regulation of biosynthetic process GO:0009891 316 0.071
dna templated transcriptional preinitiation complex assembly GO:0070897 20 0.070
male gamete generation GO:0048232 201 0.069
nuclear division GO:0000280 332 0.067
protein complex assembly GO:0006461 200 0.063
positive regulation of nucleic acid templated transcription GO:1903508 266 0.061
spindle elongation GO:0051231 83 0.060
regulation of cellular protein metabolic process GO:0032268 243 0.057
protein dna complex assembly GO:0065004 63 0.056
positive regulation of macromolecule metabolic process GO:0010604 405 0.055
posttranscriptional regulation of gene expression GO:0010608 145 0.054
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.051
regulation of phosphorylation GO:0042325 147 0.049
positive regulation of cellular biosynthetic process GO:0031328 316 0.049
dna templated transcription initiation GO:0006352 25 0.048
regulation of protein modification process GO:0031399 112 0.048
establishment of localization in cell GO:0051649 402 0.047
positive regulation of cellular protein metabolic process GO:0032270 118 0.046
regulation of intracellular signal transduction GO:1902531 236 0.043
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.043
regulation of protein metabolic process GO:0051246 256 0.042
mitotic cell cycle checkpoint GO:0007093 88 0.042
mitotic spindle organization GO:0007052 220 0.041
aging GO:0007568 143 0.039
chromosome organization GO:0051276 360 0.039
chromatin organization GO:0006325 207 0.039
mitotic dna damage checkpoint GO:0044773 74 0.038
mitotic nuclear division GO:0007067 213 0.037
purine containing compound metabolic process GO:0072521 155 0.037
regulation of gene expression epigenetic GO:0040029 128 0.036
nucleotide excision repair GO:0006289 8 0.036
dendrite development GO:0016358 204 0.035
negative regulation of cell differentiation GO:0045596 143 0.034
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.034
determination of adult lifespan GO:0008340 137 0.033
body morphogenesis GO:0010171 2 0.033
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.032
regulation of plasmatocyte differentiation GO:0045613 6 0.032
appendage development GO:0048736 401 0.032
organonitrogen compound metabolic process GO:1901564 318 0.032
intracellular signal transduction GO:0035556 300 0.032
protein destabilization GO:0031648 2 0.031
dna integrity checkpoint GO:0031570 81 0.031
negative regulation of gene expression GO:0010629 387 0.030
positive regulation of rna metabolic process GO:0051254 271 0.030
microtubule organizing center organization GO:0031023 168 0.030
mitotic g2 m transition checkpoint GO:0044818 70 0.029
positive regulation of rna biosynthetic process GO:1902680 266 0.029
organelle assembly GO:0070925 198 0.029
regulation of locomotion GO:0040012 42 0.026
regulation of cellular catabolic process GO:0031329 157 0.026
rna interference GO:0016246 27 0.026
positive regulation of transcription dna templated GO:0045893 266 0.026
multicellular organismal aging GO:0010259 140 0.025
positive regulation of catabolic process GO:0009896 105 0.024
oxoacid metabolic process GO:0043436 103 0.024
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.024
positive regulation of gene expression GO:0010628 290 0.024
negative regulation of cell cycle process GO:0010948 109 0.024
regulation of molecular function GO:0065009 217 0.023
regulation of multicellular organismal development GO:2000026 414 0.023
phosphorylation GO:0016310 294 0.023
regulation of mitotic cell cycle GO:0007346 190 0.023
spindle assembly involved in mitosis GO:0090307 50 0.022
cellular protein modification process GO:0006464 438 0.022
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 20 0.022
regulation of proteolysis GO:0030162 87 0.022
regulation of cell differentiation GO:0045595 302 0.021
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.021
heterocycle catabolic process GO:0046700 166 0.021
purine nucleoside triphosphate catabolic process GO:0009146 108 0.021
regulation of proteasomal protein catabolic process GO:0061136 39 0.020
positive regulation of proteolysis GO:0045862 52 0.020
taxis GO:0042330 304 0.019
regulation of phosphate metabolic process GO:0019220 210 0.019
molting cycle GO:0042303 56 0.019
establishment of protein localization GO:0045184 163 0.019
cellular macromolecule localization GO:0070727 220 0.019
protein modification by small protein conjugation or removal GO:0070647 106 0.018
small molecule metabolic process GO:0044281 305 0.018
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.018
positive regulation of cellular catabolic process GO:0031331 95 0.018
g2 dna damage checkpoint GO:0031572 69 0.018
regulation of cell cycle phase transition GO:1901987 130 0.018
appendage morphogenesis GO:0035107 397 0.018
purine ribonucleotide catabolic process GO:0009154 109 0.018
single organism catabolic process GO:0044712 228 0.018
small gtpase mediated signal transduction GO:0007264 88 0.018
negative regulation of mitotic cell cycle GO:0045930 109 0.017
cellular protein complex assembly GO:0043623 71 0.017
protein ubiquitination GO:0016567 70 0.017
regulation of cell cycle GO:0051726 291 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.017
protein transport GO:0015031 155 0.017
cell cycle checkpoint GO:0000075 95 0.016
organic substance transport GO:0071702 257 0.016
meiotic cell cycle process GO:1903046 132 0.016
regulation of cell proliferation GO:0042127 163 0.016
dna damage checkpoint GO:0000077 78 0.016
dna repair GO:0006281 54 0.016
response to nitrogen compound GO:1901698 90 0.016
gene silencing by rna GO:0031047 57 0.016
regulation of mitotic cell cycle phase transition GO:1901990 130 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
protein modification process GO:0036211 438 0.016
aromatic compound catabolic process GO:0019439 166 0.015
nucleoside metabolic process GO:0009116 127 0.015
imaginal disc derived wing morphogenesis GO:0007476 337 0.015
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.015
ribonucleotide metabolic process GO:0009259 145 0.015
regulation of ras protein signal transduction GO:0046578 93 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
regulation of gtpase activity GO:0043087 44 0.015
single organism behavior GO:0044708 391 0.015
mitotic dna integrity checkpoint GO:0044774 75 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
single organism intracellular transport GO:1902582 207 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.014
positive regulation of cellular component biogenesis GO:0044089 80 0.014
positive regulation of cellular component organization GO:0051130 156 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.014
cell recognition GO:0008037 102 0.013
positive regulation of response to stimulus GO:0048584 323 0.013
response to light stimulus GO:0009416 124 0.013
phagocytosis GO:0006909 215 0.013
histolysis GO:0007559 102 0.013
regulation of cell cycle process GO:0010564 181 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
ras protein signal transduction GO:0007265 88 0.013
positive regulation of protein complex assembly GO:0031334 22 0.013
organophosphate catabolic process GO:0046434 112 0.013
secretion by cell GO:0032940 101 0.012
regulation of catabolic process GO:0009894 170 0.012
cell motility GO:0048870 251 0.012
response to oxygen containing compound GO:1901700 200 0.012
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 1 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
cellular protein localization GO:0034613 160 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
negative regulation of phosphate metabolic process GO:0045936 45 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
response to organic substance GO:0010033 284 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
er associated ubiquitin dependent protein catabolic process GO:0030433 3 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
positive regulation of cell communication GO:0010647 250 0.011
gland development GO:0048732 191 0.011
cellular homeostasis GO:0019725 80 0.011
regulation of phosphatase activity GO:0010921 3 0.011
intracellular transport GO:0046907 228 0.011
positive regulation of protein modification process GO:0031401 58 0.011
homeostatic process GO:0042592 199 0.011
response to external biotic stimulus GO:0043207 293 0.010
chromatin modification GO:0016568 147 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
regulation of rac gtpase activity GO:0032314 1 0.010
cell cycle phase transition GO:0044770 140 0.010

Pros29 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
disease of cellular proliferation DOID:14566 0 0.010
benign neoplasm DOID:0060072 0 0.010