Drosophila melanogaster

107 known processes

Cp190 (Dmel_CG6384)

Centrosomal protein 190kD

(Aliases: Rb188,Dmel\CG6384,CP-190,CEN190,Dmap190,Cen185,Map190,CP190,E(mod)4-1,Bx63,CG6384,DMAP190,AbS1-4,CP-60,dmap190,Cen190,DMAP-190)

Cp190 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromosome organization GO:0051276 360 0.992
positive regulation of cellular biosynthetic process GO:0031328 316 0.987
regulation of cell cycle GO:0051726 291 0.971
nuclear division GO:0000280 332 0.970
organelle fission GO:0048285 340 0.963
mitotic spindle organization GO:0007052 220 0.952
positive regulation of transcription dna templated GO:0045893 266 0.944
regulation of mitotic cell cycle GO:0007346 190 0.938
protein complex biogenesis GO:0070271 201 0.929
regulation of cell cycle phase transition GO:1901987 130 0.925
regulation of cell cycle process GO:0010564 181 0.881
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.869
mitotic nuclear division GO:0007067 213 0.859
macromolecular complex assembly GO:0065003 256 0.833
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.827
positive regulation of gene expression GO:0010628 290 0.806
negative regulation of cell cycle GO:0045786 116 0.805
positive regulation of rna biosynthetic process GO:1902680 266 0.802
positive regulation of macromolecule metabolic process GO:0010604 405 0.797
cell division GO:0051301 248 0.792
protein complex assembly GO:0006461 200 0.788
positive regulation of nucleic acid templated transcription GO:1903508 266 0.788
cell proliferation GO:0008283 299 0.702
cell motility GO:0048870 251 0.701
positive regulation of rna metabolic process GO:0051254 271 0.693
vesicle mediated transport GO:0016192 381 0.675
mitotic cell cycle phase transition GO:0044772 138 0.665
transcription from rna polymerase ii promoter GO:0006366 368 0.641
negative regulation of transcription dna templated GO:0045892 237 0.635
positive regulation of biosynthetic process GO:0009891 316 0.629
chromosome segregation GO:0007059 157 0.620
negative regulation of rna metabolic process GO:0051253 251 0.612
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.592
gonad development GO:0008406 50 0.570
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.552
negative regulation of cell cycle phase transition GO:1901988 103 0.521
cellular macromolecular complex assembly GO:0034622 153 0.497
microtubule organizing center organization GO:0031023 168 0.468
positive regulation of response to stimulus GO:0048584 323 0.462
embryo development ending in birth or egg hatching GO:0009792 152 0.437
development of primary sexual characteristics GO:0045137 50 0.436
endomembrane system organization GO:0010256 119 0.417
regulation of immune system process GO:0002682 176 0.409
sister chromatid segregation GO:0000819 92 0.408
negative regulation of rna biosynthetic process GO:1902679 240 0.378
dna metabolic process GO:0006259 227 0.365
negative regulation of nucleic acid templated transcription GO:1903507 240 0.358
establishment of organelle localization GO:0051656 122 0.357
response to other organism GO:0051707 293 0.353
negative regulation of mitotic cell cycle GO:0045930 109 0.349
nuclear migration GO:0007097 20 0.348
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.347
negative regulation of cellular metabolic process GO:0031324 382 0.335
regulation of mitotic cell cycle phase transition GO:1901990 130 0.310
regulation of growth GO:0040008 233 0.298
endocytosis GO:0006897 310 0.297
dendrite development GO:0016358 204 0.292
spindle organization GO:0007051 253 0.282
developmental growth GO:0048589 280 0.276
apoptotic process GO:0006915 159 0.273
central nervous system development GO:0007417 201 0.270
growth GO:0040007 359 0.264
muscle structure development GO:0061061 224 0.255
programmed cell death GO:0012501 257 0.254
regulation of organelle organization GO:0033043 196 0.247
positive regulation of signaling GO:0023056 243 0.243
mitotic sister chromatid segregation GO:0000070 87 0.241
cell cycle phase transition GO:0044770 140 0.231
dendrite morphogenesis GO:0048813 199 0.230
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.227
regulation of cellular protein metabolic process GO:0032268 243 0.224
death GO:0016265 284 0.223
stem cell proliferation GO:0072089 88 0.220
regionalization GO:0003002 416 0.220
stem cell differentiation GO:0048863 117 0.219
negative regulation of cellular biosynthetic process GO:0031327 277 0.216
negative regulation of biosynthetic process GO:0009890 277 0.212
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.208
regulation of cell proliferation GO:0042127 163 0.206
ameboidal type cell migration GO:0001667 151 0.200
negative regulation of cell cycle process GO:0010948 109 0.194
immune system process GO:0002376 347 0.189
sex differentiation GO:0007548 81 0.186
establishment of localization in cell GO:0051649 402 0.186
negative regulation of cell death GO:0060548 81 0.183
regulation of response to stress GO:0080134 200 0.180
regulation of programmed cell death GO:0043067 152 0.180
reproductive structure development GO:0048608 74 0.176
positive regulation of signal transduction GO:0009967 223 0.173
cell death GO:0008219 279 0.170
regulation of protein localization GO:0032880 76 0.166
meiotic nuclear division GO:0007126 151 0.158
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.157
neuroblast proliferation GO:0007405 74 0.151
regulation of dna metabolic process GO:0051052 34 0.143
positive regulation of intracellular signal transduction GO:1902533 116 0.143
regulation of intracellular protein transport GO:0033157 46 0.142
cellular response to chemical stimulus GO:0070887 199 0.137
positive regulation of cell cycle GO:0045787 43 0.137
centriole replication GO:0007099 24 0.137
reproductive system development GO:0061458 74 0.135
single organism cellular localization GO:1902580 180 0.134
muscle organ development GO:0007517 127 0.133
regulation of cell morphogenesis GO:0022604 163 0.127
regulation of nucleocytoplasmic transport GO:0046822 35 0.117
regulation of cell division GO:0051302 72 0.116
response to external biotic stimulus GO:0043207 293 0.115
male gamete generation GO:0048232 201 0.112
organelle localization GO:0051640 148 0.112
eye development GO:0001654 323 0.110
eye morphogenesis GO:0048592 260 0.110
mesenchymal cell differentiation GO:0048762 1 0.109
negative regulation of cell differentiation GO:0045596 143 0.108
digestive tract development GO:0048565 149 0.106
protein import into nucleus GO:0006606 51 0.105
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.103
positive regulation of cell communication GO:0010647 250 0.102
response to biotic stimulus GO:0009607 294 0.102
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.102
cellular macromolecule localization GO:0070727 220 0.100
regulation of protein transport GO:0051223 57 0.099
spermatogenesis GO:0007283 200 0.093
regulation of multicellular organismal development GO:2000026 414 0.091
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.089
regulation of intracellular transport GO:0032386 64 0.087
nucleus localization GO:0051647 34 0.087
negative regulation of developmental process GO:0051093 201 0.086
negative regulation of gene expression GO:0010629 387 0.085
regulation of transport GO:0051049 181 0.085
meiotic cell cycle process GO:1903046 132 0.084
signal transduction by phosphorylation GO:0023014 107 0.084
phosphorylation GO:0016310 294 0.083
body morphogenesis GO:0010171 2 0.082
regulation of protein metabolic process GO:0051246 256 0.080
cell migration GO:0016477 238 0.080
centrosome duplication GO:0051298 121 0.079
positive regulation of protein import into nucleus GO:0042307 21 0.078
histone modification GO:0016570 106 0.077
localization of cell GO:0051674 257 0.076
protein modification process GO:0036211 438 0.076
meiotic cell cycle GO:0051321 171 0.074
regulation of localization GO:0032879 275 0.073
cell adhesion GO:0007155 136 0.072
cardiovascular system development GO:0072358 82 0.071
regulation of intracellular signal transduction GO:1902531 236 0.070
centrosome cycle GO:0007098 137 0.069
regulation of protein localization to nucleus GO:1900180 29 0.068
genitalia development GO:0048806 26 0.068
regulation of cytoplasmic transport GO:1903649 47 0.066
organic substance transport GO:0071702 257 0.065
chromatin modification GO:0016568 147 0.065
digestive system development GO:0055123 149 0.065
mitotic cell cycle checkpoint GO:0007093 88 0.063
positive regulation of immune system process GO:0002684 68 0.060
response to organic substance GO:0010033 284 0.060
head development GO:0060322 135 0.059
protein import GO:0017038 55 0.058
cellular protein localization GO:0034613 160 0.058
negative regulation of cell proliferation GO:0008285 69 0.058
positive regulation of protein transport GO:0051222 37 0.057
nuclear transport GO:0051169 72 0.056
cellular protein modification process GO:0006464 438 0.056
cell cycle g1 s phase transition GO:0044843 31 0.052
regulation of anatomical structure morphogenesis GO:0022603 242 0.051
centrosome organization GO:0051297 163 0.050
regulation of cell death GO:0010941 173 0.048
cell type specific apoptotic process GO:0097285 38 0.047
cellular protein complex assembly GO:0043623 71 0.047
intracellular transport GO:0046907 228 0.045
regulation of developmental growth GO:0048638 174 0.044
negative regulation of protein metabolic process GO:0051248 85 0.044
determination of adult lifespan GO:0008340 137 0.042
establishment of protein localization GO:0045184 163 0.042
negative regulation of multicellular organismal process GO:0051241 142 0.042
regulation of phosphorylation GO:0042325 147 0.042
single organism intracellular transport GO:1902582 207 0.041
chromosome separation GO:0051304 42 0.040
regulation of cellular response to stress GO:0080135 89 0.040
regulation of cellular localization GO:0060341 136 0.040
oocyte differentiation GO:0009994 145 0.040
regulation of cytoskeleton organization GO:0051493 89 0.040
camera type eye development GO:0043010 4 0.040
regulation of mitosis GO:0007088 56 0.040
mrna metabolic process GO:0016071 124 0.039
brain development GO:0007420 120 0.039
cell maturation GO:0048469 144 0.038
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.038
renal tubule development GO:0061326 64 0.038
dorsal ventral pattern formation GO:0009953 133 0.037
compound eye development GO:0048749 307 0.037
negative regulation of protein secretion GO:0050709 2 0.037
centriole assembly GO:0098534 24 0.036
positive regulation of immune response GO:0050778 63 0.035
neuron apoptotic process GO:0051402 17 0.035
diterpenoid biosynthetic process GO:0016102 1 0.035
developmental maturation GO:0021700 172 0.034
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.034
regulation of cell differentiation GO:0045595 302 0.033
regulation of immune response GO:0050776 118 0.032
mitotic cell cycle embryonic GO:0045448 38 0.032
golgi organization GO:0007030 66 0.032
response to endogenous stimulus GO:0009719 119 0.032
maternal determination of dorsal ventral axis ovarian follicular epithelium germ line encoded GO:0008070 2 0.032
posttranscriptional regulation of gene expression GO:0010608 145 0.032
regulation of nuclear division GO:0051783 58 0.032
axon development GO:0061564 297 0.032
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.032
cranial nerve development GO:0021545 1 0.032
regulation of neuron apoptotic process GO:0043523 16 0.031
asymmetric neuroblast division resulting in ganglion mother cell formation GO:0055060 2 0.031
positive regulation of protein metabolic process GO:0051247 128 0.031
intracellular signal transduction GO:0035556 300 0.031
intracellular protein transport GO:0006886 104 0.030
protein transport GO:0015031 155 0.030
response to oxygen containing compound GO:1901700 200 0.030
negative regulation of cellular protein metabolic process GO:0032269 85 0.030
response to organic cyclic compound GO:0014070 89 0.030
cytoplasmic microtubule organization GO:0031122 22 0.030
meiotic chromosome segregation GO:0045132 59 0.030
nitrogen compound transport GO:0071705 85 0.029
epithelial cell migration GO:0010631 148 0.029
positive regulation of mitotic cell cycle GO:0045931 34 0.029
single organism nuclear import GO:1902593 51 0.029
segmentation GO:0035282 207 0.029
regulation of apoptotic process GO:0042981 130 0.029
anterior posterior axis specification follicular epithelium GO:0030714 2 0.029
ubiquitin dependent protein catabolic process GO:0006511 78 0.029
protein targeting to nucleus GO:0044744 51 0.028
proteolysis GO:0006508 192 0.028
protein localization to nucleus GO:0034504 55 0.028
positive regulation of transport GO:0051050 92 0.028
tissue migration GO:0090130 155 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.028
neural precursor cell proliferation GO:0061351 75 0.028
protein modification by small protein conjugation or removal GO:0070647 106 0.028
regulation of striated muscle contraction GO:0006942 2 0.027
catabolic process GO:0009056 409 0.027
sensory organ morphogenesis GO:0090596 260 0.027
atp metabolic process GO:0046034 49 0.026
defense response GO:0006952 300 0.026
small molecule metabolic process GO:0044281 305 0.026
protein phosphorylation GO:0006468 169 0.026
biological adhesion GO:0022610 138 0.026
negative regulation of gene expression epigenetic GO:0045814 77 0.026
positive regulation of cell death GO:0010942 69 0.026
regulation of microtubule based process GO:0032886 49 0.025
single organism biosynthetic process GO:0044711 206 0.025
positive regulation of cellular protein metabolic process GO:0032270 118 0.025
carboxylic acid metabolic process GO:0019752 92 0.025
regulation of microtubule cytoskeleton organization GO:0070507 41 0.025
response to abiotic stimulus GO:0009628 341 0.024
protein targeting GO:0006605 64 0.024
positive regulation of phosphorylation GO:0042327 87 0.024
ribonucleoside monophosphate metabolic process GO:0009161 51 0.024
embryonic morphogenesis GO:0048598 206 0.024
cell cycle checkpoint GO:0000075 95 0.023
phagocytosis GO:0006909 215 0.023
pronuclear fusion GO:0007344 4 0.023
nucleoside monophosphate metabolic process GO:0009123 52 0.023
response to drug GO:0042493 17 0.023
organonitrogen compound metabolic process GO:1901564 318 0.023
organic acid metabolic process GO:0006082 103 0.023
nuclear axial expansion GO:0035191 3 0.022
axis specification GO:0009798 167 0.022
mitochondrial membrane organization GO:0007006 3 0.021
chromatin organization GO:0006325 207 0.021
tube morphogenesis GO:0035239 191 0.021
dna repair GO:0006281 54 0.021
neuron projection guidance GO:0097485 241 0.021
immune system development GO:0002520 57 0.020
renal system development GO:0072001 72 0.020
immune effector process GO:0002252 98 0.020
negative regulation of programmed cell death GO:0043069 72 0.020
cellular amine metabolic process GO:0044106 12 0.019
response to radiation GO:0009314 155 0.019
covalent chromatin modification GO:0016569 106 0.019
response to hypoxia GO:0001666 53 0.019
regulation of protein modification process GO:0031399 112 0.019
regulation of nervous system development GO:0051960 248 0.019
regulation of response to external stimulus GO:0032101 115 0.019
dorsal closure leading edge cell differentiation GO:0046663 2 0.018
meiosis i GO:0007127 59 0.018
multicellular organismal aging GO:0010259 140 0.018
modification dependent protein catabolic process GO:0019941 78 0.018
cellular catabolic process GO:0044248 372 0.018
cellular response to nutrient GO:0031670 1 0.018
forebrain development GO:0030900 2 0.017
negative regulation of apoptotic process GO:0043066 63 0.017
microtubule polymerization or depolymerization GO:0031109 39 0.017
positive regulation of developmental process GO:0051094 143 0.017
nitric oxide metabolic process GO:0046209 1 0.017
spermatid differentiation GO:0048515 114 0.017
maintenance of location GO:0051235 73 0.016
gland development GO:0048732 191 0.016
stem cell development GO:0048864 79 0.016
epithelium migration GO:0090132 148 0.016
aging GO:0007568 143 0.016
regulation of embryonic development GO:0045995 68 0.016
telencephalon development GO:0021537 2 0.016
positive regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis GO:2001272 4 0.016
oxoacid metabolic process GO:0043436 103 0.016
regulation of establishment of protein localization GO:0070201 61 0.016
positive regulation of epidermal growth factor activated receptor activity GO:0045741 1 0.015
wnt signaling pathway GO:0016055 98 0.015
regulation of mapk cascade GO:0043408 92 0.015
protein localization GO:0008104 284 0.015
protein localization to organelle GO:0033365 82 0.015
meiotic chromosome movement towards spindle pole GO:0016344 1 0.015
regulation of protein import into nucleus GO:0042306 28 0.015
regulation of atp metabolic process GO:1903578 6 0.015
regulation of multi organism process GO:0043900 131 0.015
nucleocytoplasmic transport GO:0006913 72 0.014
negative regulation of meiotic cell cycle phase transition GO:1901994 1 0.014
morphogenesis of an epithelium GO:0002009 276 0.014
neurological system process GO:0050877 358 0.014
regulation of cellular component biogenesis GO:0044087 201 0.014
regulation of protein targeting GO:1903533 29 0.014
response to extracellular stimulus GO:0009991 116 0.014
response to organonitrogen compound GO:0010243 75 0.014
dorsal ventral axis specification GO:0009950 66 0.014
cellular response to growth factor stimulus GO:0071363 30 0.014
establishment of protein localization to organelle GO:0072594 62 0.014
regulation of immune effector process GO:0002697 52 0.014
chromatin remodeling GO:0006338 72 0.014
regulation of protein phosphorylation GO:0001932 64 0.014
regulation of molecular function GO:0065009 217 0.014
neuron maturation GO:0042551 31 0.014
hematopoietic progenitor cell differentiation GO:0002244 1 0.013
immune response GO:0006955 246 0.013
columnar cuboidal epithelial cell development GO:0002066 249 0.013
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.013
spindle assembly GO:0051225 80 0.013
mesenchymal cell development GO:0014031 1 0.013
nuclear pore organization GO:0006999 1 0.013
response to growth factor GO:0070848 31 0.013
macromolecule catabolic process GO:0009057 161 0.013
purine nucleoside monophosphate metabolic process GO:0009126 50 0.013
positive regulation of intracellular transport GO:0032388 42 0.013
oocyte morphogenesis GO:0048601 3 0.012
negative regulation of nucleotide metabolic process GO:0045980 4 0.012
regulation of neuron death GO:1901214 26 0.012
regulation of atp catabolic process GO:1903289 4 0.012
mapk cascade GO:0000165 107 0.012
negative regulation of terminal cell fate specification open tracheal system GO:0035155 2 0.012
circulatory system development GO:0072359 82 0.012
taxis GO:0042330 304 0.012
embryonic pattern specification GO:0009880 174 0.012
regulation of cell development GO:0060284 215 0.012
skeletal muscle tissue development GO:0007519 13 0.012
regulation of cellular protein catabolic process GO:1903362 44 0.012
oocyte fate commitment GO:0048600 2 0.012
glial cell differentiation GO:0010001 35 0.012
formation of a compartment boundary GO:0060288 4 0.011
dna replication GO:0006260 48 0.011
protein dna complex subunit organization GO:0071824 86 0.011
amine metabolic process GO:0009308 12 0.011
dendrite regeneration GO:0031104 2 0.011
male meiosis GO:0007140 52 0.011
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 20 0.011
negative regulation of signal transduction GO:0009968 206 0.011
g1 s transition of mitotic cell cycle GO:0000082 31 0.011
hindbrain development GO:0030902 2 0.011
regulation of cell proliferation involved in compound eye morphogenesis GO:2000495 2 0.011
maternal determination of dorsal ventral axis ovarian follicular epithelium soma encoded GO:0008071 1 0.011
defense response to other organism GO:0098542 225 0.011
rna processing GO:0006396 147 0.011
regulation of kinase activity GO:0043549 53 0.010
proteasomal protein catabolic process GO:0010498 59 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.010
chitin based larval cuticle pattern formation GO:0035293 11 0.010

Cp190 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
osteochondrodysplasia DOID:2256 0 0.069
osteogenesis imperfecta DOID:12347 0 0.069
bone development disease DOID:0080006 0 0.069
bone disease DOID:0080001 0 0.069
disease of anatomical entity DOID:7 0 0.069
musculoskeletal system disease DOID:17 0 0.069
connective tissue disease DOID:65 0 0.069
reproductive organ cancer DOID:193 0 0.012
ovarian cancer DOID:2394 0 0.012
female reproductive organ cancer DOID:120 0 0.012
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
nervous system benign neoplasm DOID:0060115 0 0.011
organ system benign neoplasm DOID:0060085 0 0.011
neuroma DOID:2001 0 0.011
benign neoplasm DOID:0060072 0 0.011