Drosophila melanogaster

45 known processes

Gdh (Dmel_CG5320)

Glutamate dehydrogenase

(Aliases: GLU-D,Dmel\CG5320,gdh,DHE3,GLUD pre-mRNA,GDH,GLUD,Glud,CG5320)

Gdh biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
catabolic process GO:0009056 409 0.592
single organism catabolic process GO:0044712 228 0.378
organic acid metabolic process GO:0006082 103 0.366
small molecule metabolic process GO:0044281 305 0.330
nadh metabolic process GO:0006734 1 0.314
organonitrogen compound metabolic process GO:1901564 318 0.291
energy derivation by oxidation of organic compounds GO:0015980 32 0.276
nad metabolic process GO:0019674 1 0.272
cell cell signaling involved in cell fate commitment GO:0045168 210 0.271
oxidation reduction process GO:0055114 123 0.232
carboxylic acid metabolic process GO:0019752 92 0.230
oxidoreduction coenzyme metabolic process GO:0006733 2 0.228
organic substance catabolic process GO:1901575 308 0.210
oxoacid metabolic process GO:0043436 103 0.198
nucleotide metabolic process GO:0009117 161 0.149
nicotinamide nucleotide metabolic process GO:0046496 2 0.147
centrosome organization GO:0051297 163 0.137
alpha amino acid metabolic process GO:1901605 20 0.114
lateral inhibition GO:0046331 206 0.111
organophosphate metabolic process GO:0019637 195 0.104
tricarboxylic acid metabolic process GO:0072350 1 0.087
cellular catabolic process GO:0044248 372 0.083
establishment of localization in cell GO:0051649 402 0.074
organonitrogen compound catabolic process GO:1901565 128 0.071
death GO:0016265 284 0.065
defense response to other organism GO:0098542 225 0.064
nucleoside phosphate metabolic process GO:0006753 162 0.060
endocytosis GO:0006897 310 0.060
nucleobase containing small molecule metabolic process GO:0055086 174 0.059
vesicle mediated transport GO:0016192 381 0.052
regulation of multicellular organismal development GO:2000026 414 0.051
positive regulation of signaling GO:0023056 243 0.051
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.049
purine containing compound catabolic process GO:0072523 112 0.048
purine nucleoside metabolic process GO:0042278 127 0.048
apoptotic process GO:0006915 159 0.048
carbohydrate derivative catabolic process GO:1901136 118 0.047
organonitrogen compound biosynthetic process GO:1901566 117 0.047
ribonucleoside catabolic process GO:0042454 112 0.046
regionalization GO:0003002 416 0.045
cell death GO:0008219 279 0.045
cellular respiration GO:0045333 26 0.044
ribonucleotide metabolic process GO:0009259 145 0.044
cellular carbohydrate catabolic process GO:0044275 2 0.043
multicellular organismal reproductive behavior GO:0033057 110 0.043
ribonucleoside monophosphate catabolic process GO:0009158 39 0.043
immune system process GO:0002376 347 0.043
purine ribonucleoside metabolic process GO:0046128 127 0.042
body morphogenesis GO:0010171 2 0.041
nucleoside metabolic process GO:0009116 127 0.041
cellular nitrogen compound catabolic process GO:0044270 165 0.041
positive regulation of macromolecule metabolic process GO:0010604 405 0.041
purine ribonucleotide metabolic process GO:0009150 145 0.040
ion transport GO:0006811 145 0.038
growth GO:0040007 359 0.038
programmed cell death GO:0012501 257 0.038
purine nucleoside catabolic process GO:0006152 112 0.037
nucleobase containing compound catabolic process GO:0034655 165 0.036
inorganic cation transmembrane transport GO:0098662 61 0.035
nucleoside triphosphate catabolic process GO:0009143 108 0.034
phagocytosis GO:0006909 215 0.034
epithelial cell differentiation GO:0030855 322 0.034
pyridine containing compound metabolic process GO:0072524 3 0.034
glycosyl compound metabolic process GO:1901657 127 0.033
ribonucleoside metabolic process GO:0009119 127 0.033
kidney development GO:0001822 3 0.033
dorsal ventral pattern formation GO:0009953 133 0.032
ribonucleoside monophosphate metabolic process GO:0009161 51 0.032
positive regulation of transport GO:0051050 92 0.031
regulation of ion transport GO:0043269 39 0.031
ribose phosphate metabolic process GO:0019693 145 0.030
embryo development ending in birth or egg hatching GO:0009792 152 0.030
positive regulation of cell communication GO:0010647 250 0.029
cellular component assembly involved in morphogenesis GO:0010927 151 0.029
developmental growth GO:0048589 280 0.029
monovalent inorganic cation transport GO:0015672 40 0.029
organophosphate catabolic process GO:0046434 112 0.029
regulation of immune response GO:0050776 118 0.029
nucleoside monophosphate metabolic process GO:0009123 52 0.029
purine nucleoside biosynthetic process GO:0042451 3 0.029
imaginal disc derived wing morphogenesis GO:0007476 337 0.028
purine ribonucleoside catabolic process GO:0046130 112 0.028
regulation of cellular ketone metabolic process GO:0010565 3 0.028
glycosyl compound catabolic process GO:1901658 112 0.028
negative regulation of cellular metabolic process GO:0031324 382 0.028
regulation of growth GO:0040008 233 0.027
heterocycle catabolic process GO:0046700 166 0.027
actin cytoskeleton organization GO:0030036 206 0.026
neuromuscular junction development GO:0007528 149 0.026
atp metabolic process GO:0046034 49 0.026
small molecule catabolic process GO:0044282 21 0.026
nucleoside phosphate catabolic process GO:1901292 110 0.026
intracellular transport GO:0046907 228 0.026
defense response to gram negative bacterium GO:0050829 94 0.025
regulation of response to stress GO:0080134 200 0.025
purine ribonucleoside monophosphate biosynthetic process GO:0009168 3 0.025
purine containing compound metabolic process GO:0072521 155 0.025
purine ribonucleotide catabolic process GO:0009154 109 0.025
nucleoside catabolic process GO:0009164 112 0.025
regulation of localization GO:0032879 275 0.025
carbohydrate derivative metabolic process GO:1901135 217 0.025
aromatic compound catabolic process GO:0019439 166 0.024
cation transport GO:0006812 110 0.024
actin filament based process GO:0030029 220 0.023
purine nucleotide metabolic process GO:0006163 146 0.023
organic substance transport GO:0071702 257 0.022
protein complex assembly GO:0006461 200 0.022
purine nucleoside triphosphate catabolic process GO:0009146 108 0.022
carbohydrate metabolic process GO:0005975 82 0.022
generation of precursor metabolites and energy GO:0006091 42 0.021
ribonucleoside biosynthetic process GO:0042455 3 0.021
organic cyclic compound catabolic process GO:1901361 168 0.021
metal ion homeostasis GO:0055065 44 0.021
regulation of transport GO:0051049 181 0.020
central nervous system development GO:0007417 201 0.020
localization of cell GO:0051674 257 0.020
regulation of immune system process GO:0002682 176 0.020
cellular amino acid metabolic process GO:0006520 61 0.020
wing disc morphogenesis GO:0007472 344 0.020
imaginal disc pattern formation GO:0007447 91 0.019
multicellular organismal aging GO:0010259 140 0.019
purine nucleotide catabolic process GO:0006195 109 0.019
response to other organism GO:0051707 293 0.019
single organism carbohydrate metabolic process GO:0044723 72 0.019
response to oxygen containing compound GO:1901700 200 0.019
larval development GO:0002164 104 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.018
appendage morphogenesis GO:0035107 397 0.018
synaptic transmission GO:0007268 288 0.018
defense response GO:0006952 300 0.018
negative regulation of biosynthetic process GO:0009890 277 0.017
protein transport GO:0015031 155 0.017
positive regulation of hydrolase activity GO:0051345 78 0.017
microtubule organizing center organization GO:0031023 168 0.017
ribonucleoside triphosphate catabolic process GO:0009203 108 0.017
head development GO:0060322 135 0.016
regulation of cellular protein metabolic process GO:0032268 243 0.016
sex differentiation GO:0007548 81 0.016
post embryonic appendage morphogenesis GO:0035120 385 0.016
protein complex biogenesis GO:0070271 201 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.016
regulation of innate immune response GO:0045088 71 0.016
behavioral response to ethanol GO:0048149 49 0.015
endomembrane system organization GO:0010256 119 0.015
appendage development GO:0048736 401 0.015
nucleoside monophosphate catabolic process GO:0009125 39 0.015
acyl coa metabolic process GO:0006637 3 0.015
reproductive system development GO:0061458 74 0.015
organelle assembly GO:0070925 198 0.015
camera type eye development GO:0043010 4 0.015
regulation of apoptotic process GO:0042981 130 0.015
reproductive behavior GO:0019098 122 0.015
digestive tract development GO:0048565 149 0.015
purine ribonucleoside biosynthetic process GO:0046129 3 0.015
cellular metal ion homeostasis GO:0006875 31 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
determination of adult lifespan GO:0008340 137 0.014
synapse organization GO:0050808 196 0.014
adult behavior GO:0030534 137 0.014
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.014
ribonucleotide catabolic process GO:0009261 109 0.014
regulation of synapse organization GO:0050807 110 0.014
protein modification process GO:0036211 438 0.014
urogenital system development GO:0001655 72 0.014
synapse assembly GO:0007416 143 0.014
multi multicellular organism process GO:0044706 123 0.014
nuclear import GO:0051170 51 0.014
positive regulation of cellular biosynthetic process GO:0031328 316 0.014
tube morphogenesis GO:0035239 191 0.014
proteolysis GO:0006508 192 0.014
regulation of cysteine type endopeptidase activity GO:2000116 27 0.013
regulation of programmed cell death GO:0043067 152 0.013
biological adhesion GO:0022610 138 0.013
cellular macromolecule localization GO:0070727 220 0.013
maintenance of location GO:0051235 73 0.013
anatomical structure homeostasis GO:0060249 97 0.013
regulation of molecular function GO:0065009 217 0.013
protein processing GO:0016485 68 0.013
negative regulation of neurogenesis GO:0050768 53 0.013
chromosome segregation GO:0007059 157 0.013
macromolecular complex assembly GO:0065003 256 0.013
negative regulation of nervous system development GO:0051961 92 0.013
positive regulation of multicellular organismal process GO:0051240 143 0.013
phosphorylation GO:0016310 294 0.013
eye development GO:0001654 323 0.013
striated muscle cell differentiation GO:0051146 90 0.012
negative regulation of signal transduction GO:0009968 206 0.012
embryonic morphogenesis GO:0048598 206 0.012
cytoplasmic transport GO:0016482 130 0.012
regulation of cell proliferation GO:0042127 163 0.012
muscle structure development GO:0061061 224 0.012
regulation of cell differentiation GO:0045595 302 0.012
negative regulation of cell development GO:0010721 62 0.012
inorganic ion transmembrane transport GO:0098660 73 0.012
reproductive structure development GO:0048608 74 0.012
cation transmembrane transport GO:0098655 88 0.012
digestive tract morphogenesis GO:0048546 127 0.011
epithelial cell development GO:0002064 274 0.011
myotube differentiation GO:0014902 46 0.011
regulation of nervous system development GO:0051960 248 0.011
citrate metabolic process GO:0006101 0 0.011
regulation of anatomical structure size GO:0090066 163 0.011
single organism cellular localization GO:1902580 180 0.011
homeostatic process GO:0042592 199 0.011
regulation of cell death GO:0010941 173 0.011
cellular protein modification process GO:0006464 438 0.011
nucleotide catabolic process GO:0009166 109 0.011
wing disc dorsal ventral pattern formation GO:0048190 47 0.011
negative regulation of cell cycle phase transition GO:1901988 103 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
cytoskeleton dependent cytokinesis GO:0061640 81 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.011
multicellular organismal homeostasis GO:0048871 41 0.011
single organism nuclear import GO:1902593 51 0.011
striated muscle cell development GO:0055002 50 0.011
defense response to bacterium GO:0042742 178 0.011
purine nucleoside monophosphate metabolic process GO:0009126 50 0.011
mating GO:0007618 120 0.011
glutamine family amino acid metabolic process GO:0009064 12 0.011
secretion by cell GO:0032940 101 0.011
cation homeostasis GO:0055080 51 0.011
cell motility GO:0048870 251 0.011
regulation of cellular localization GO:0060341 136 0.011
cellular carbohydrate metabolic process GO:0044262 22 0.011
purine nucleoside monophosphate catabolic process GO:0009128 38 0.011
regulation of endopeptidase activity GO:0052548 36 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.011
nucleoside triphosphate metabolic process GO:0009141 120 0.011
regulation of developmental growth GO:0048638 174 0.010
carboxylic acid catabolic process GO:0046395 16 0.010
negative regulation of multicellular organismal process GO:0051241 142 0.010
development of primary sexual characteristics GO:0045137 50 0.010
brain development GO:0007420 120 0.010
sensory organ morphogenesis GO:0090596 260 0.010
regulation of hydrolase activity GO:0051336 97 0.010
phosphate ion transport GO:0006817 4 0.010

Gdh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.102
nervous system disease DOID:863 0 0.028
eye disease DOID:5614 0 0.028
sensory system disease DOID:0050155 0 0.028
eye and adnexa disease DOID:1492 0 0.028
disease of metabolism DOID:0014667 0 0.015
musculoskeletal system disease DOID:17 0 0.013