Drosophila melanogaster

239 known processes

brm (Dmel_CG5942)

brahma

(Aliases: dBRM,CG18438,l(3)72Aa,dSNF2,Brm,Dmel\CG5942,E(E2F)3A,BRM,CG5942)

brm biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromosome organization GO:0051276 360 0.999
dendrite morphogenesis GO:0048813 199 0.999
cell proliferation GO:0008283 299 0.998
regulation of cell proliferation GO:0042127 163 0.998
dendrite development GO:0016358 204 0.997
positive regulation of biosynthetic process GO:0009891 316 0.996
dna conformation change GO:0071103 105 0.996
Yeast
positive regulation of transcription dna templated GO:0045893 266 0.988
cellular protein modification process GO:0006464 438 0.988
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.983
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.983
Human Yeast Mouse
positive regulation of nucleic acid templated transcription GO:1903508 266 0.978
positive regulation of cellular biosynthetic process GO:0031328 316 0.971
chromatin modification GO:0016568 147 0.958
negative regulation of cellular metabolic process GO:0031324 382 0.952
Human Yeast Mouse Rat
cell cycle phase transition GO:0044770 140 0.950
mitotic cell cycle phase transition GO:0044772 138 0.948
regulation of cell cycle phase transition GO:1901987 130 0.948
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.937
Human Yeast Mouse
protein dna complex subunit organization GO:0071824 86 0.928
Human Yeast Rat
positive regulation of cell proliferation GO:0008284 47 0.928
Mouse
positive regulation of rna biosynthetic process GO:1902680 266 0.916
positive regulation of rna metabolic process GO:0051254 271 0.913
regulation of mitotic cell cycle GO:0007346 190 0.911
positive regulation of macromolecule metabolic process GO:0010604 405 0.889
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.888
Human Yeast Mouse Rat
growth GO:0040007 359 0.882
Human Yeast Mouse
positive regulation of gene expression GO:0010628 290 0.857
regulation of neurogenesis GO:0050767 158 0.853
muscle structure development GO:0061061 224 0.842
ubiquitin dependent protein catabolic process GO:0006511 78 0.840
regulation of cell cycle process GO:0010564 181 0.838
imaginal disc derived leg morphogenesis GO:0007480 80 0.834
multicellular organismal reproductive behavior GO:0033057 110 0.824
regulation of cell cycle g1 s phase transition GO:1902806 23 0.815
modification dependent macromolecule catabolic process GO:0043632 79 0.815
imaginal disc derived wing morphogenesis GO:0007476 337 0.799
gonad development GO:0008406 50 0.797
Worm
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.787
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.780
Yeast Mouse
body morphogenesis GO:0010171 2 0.778
stem cell maintenance GO:0019827 67 0.748
Mouse
nucleosome organization GO:0034728 59 0.745
Human Yeast Rat
negative regulation of cellular biosynthetic process GO:0031327 277 0.739
Human Yeast Mouse Rat
reproductive system development GO:0061458 74 0.735
Worm
cellular catabolic process GO:0044248 372 0.733
Human Yeast Mouse
wnt signaling pathway GO:0016055 98 0.731
Human Mouse
single organism behavior GO:0044708 391 0.715
development of primary sexual characteristics GO:0045137 50 0.715
Worm
histone modification GO:0016570 106 0.683
sensory organ morphogenesis GO:0090596 260 0.682
dna metabolic process GO:0006259 227 0.679
Yeast Mouse
leg disc development GO:0035218 92 0.672
protein acetylation GO:0006473 39 0.670
regulation of nervous system development GO:0051960 248 0.668
transcription from rna polymerase ii promoter GO:0006366 368 0.667
Human Yeast Mouse
imaginal disc derived appendage development GO:0048737 399 0.654
immune system process GO:0002376 347 0.643
Mouse
posttranscriptional gene silencing GO:0016441 46 0.627
proteasomal protein catabolic process GO:0010498 59 0.625
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.625
Human Yeast Mouse Rat
epithelial cell differentiation GO:0030855 322 0.614
Mouse
negative regulation of cell proliferation GO:0008285 69 0.608
organonitrogen compound metabolic process GO:1901564 318 0.598
Human Yeast Mouse
histone h4 acetylation GO:0043967 13 0.590
dna packaging GO:0006323 91 0.587
Yeast
chromatin organization GO:0006325 207 0.578
negative regulation of cell cycle process GO:0010948 109 0.575
negative regulation of cell cycle GO:0045786 116 0.572
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.569
Human Yeast Mouse Rat
rhythmic process GO:0048511 106 0.567
leg disc morphogenesis GO:0007478 80 0.561
camera type eye development GO:0043010 4 0.549
Human Mouse
regulation of cell death GO:0010941 173 0.547
Mouse
internal protein amino acid acetylation GO:0006475 38 0.538
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.532
protein acylation GO:0043543 42 0.530
actin filament based process GO:0030029 220 0.525
regulation of proteasomal protein catabolic process GO:0061136 39 0.517
brain development GO:0007420 120 0.506
Mouse
multi organism behavior GO:0051705 175 0.500
protein modification process GO:0036211 438 0.496
negative regulation of biosynthetic process GO:0009890 277 0.489
Human Yeast Mouse Rat
chromatin assembly or disassembly GO:0006333 52 0.487
Human Yeast Rat
sex differentiation GO:0007548 81 0.486
Worm
positive regulation of response to stimulus GO:0048584 323 0.461
cell cycle g1 s phase transition GO:0044843 31 0.454
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.453
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.452
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.451
negative regulation of gene expression GO:0010629 387 0.442
Human Yeast Mouse Rat
regulation of gene silencing GO:0060968 63 0.435
muscle cell development GO:0055001 50 0.429
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.428
regulation of cell cycle GO:0051726 291 0.405
negative regulation of neuroblast proliferation GO:0007406 27 0.404
covalent chromatin modification GO:0016569 106 0.403
regulation of neuron differentiation GO:0045664 103 0.403
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.395
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.393
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.376
Human Yeast Mouse Rat
modification dependent protein catabolic process GO:0019941 78 0.374
regulation of gene expression epigenetic GO:0040029 128 0.374
Yeast Mouse
response to organic substance GO:0010033 284 0.369
death GO:0016265 284 0.364
Mouse
regulation of rna splicing GO:0043484 69 0.362
retina development in camera type eye GO:0060041 4 0.359
Human
digestive tract development GO:0048565 149 0.355
regulation of cell development GO:0060284 215 0.348
regionalization GO:0003002 416 0.348
cell death GO:0008219 279 0.348
Mouse
axon guidance GO:0007411 233 0.343
sister chromatid segregation GO:0000819 92 0.333
negative regulation of cell cycle phase transition GO:1901988 103 0.329
intracellular receptor signaling pathway GO:0030522 19 0.322
Human
meiotic cell cycle process GO:1903046 132 0.320
aging GO:0007568 143 0.315
spindle organization GO:0007051 253 0.312
negative regulation of cell cycle g1 s phase transition GO:1902807 13 0.299
embryonic development via the syncytial blastoderm GO:0001700 148 0.293
regulation of cellular protein metabolic process GO:0032268 243 0.291
digestive system development GO:0055123 149 0.290
stem cell development GO:0048864 79 0.289
Mouse
photoreceptor cell differentiation GO:0046530 170 0.274
response to organic cyclic compound GO:0014070 89 0.268
regulation of apoptotic process GO:0042981 130 0.268
Mouse
eye photoreceptor cell differentiation GO:0001754 145 0.268
embryonic morphogenesis GO:0048598 206 0.266
Mouse
positive regulation of developmental process GO:0051094 143 0.265
Yeast Mouse
response to external biotic stimulus GO:0043207 293 0.263
muscle cell differentiation GO:0042692 103 0.261
Mouse
peptidyl lysine modification GO:0018205 57 0.259
posttranscriptional regulation of gene expression GO:0010608 145 0.250
mitotic sister chromatid segregation GO:0000070 87 0.246
multi multicellular organism process GO:0044706 123 0.243
imaginal disc derived appendage morphogenesis GO:0035114 395 0.241
eye morphogenesis GO:0048592 260 0.240
regulation of protein catabolic process GO:0042176 55 0.239
proteolysis GO:0006508 192 0.236
ovarian follicle cell development GO:0030707 248 0.234
spermatogenesis GO:0007283 200 0.232
Rat
vesicle mediated transport GO:0016192 381 0.228
negative regulation of mitotic cell cycle GO:0045930 109 0.225
positive regulation of protein metabolic process GO:0051247 128 0.223
negative regulation of transcription dna templated GO:0045892 237 0.220
Human Yeast Mouse Rat
response to biotic stimulus GO:0009607 294 0.217
regulation of chromatin modification GO:1903308 28 0.213
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.209
mitotic spindle organization GO:0007052 220 0.206
nucleus localization GO:0051647 34 0.204
response to oxygen containing compound GO:1901700 200 0.204
negative regulation of signal transduction GO:0009968 206 0.201
Human
positive regulation of catabolic process GO:0009896 105 0.193
protein modification by small protein conjugation GO:0032446 79 0.193
heart morphogenesis GO:0003007 32 0.192
Mouse
negative regulation of cellular protein metabolic process GO:0032269 85 0.190
columnar cuboidal epithelial cell development GO:0002066 249 0.189
cellular protein localization GO:0034613 160 0.187
regulation of chromatin organization GO:1902275 32 0.185
interspecies interaction between organisms GO:0044419 16 0.185
Human
peptidyl lysine acetylation GO:0018394 39 0.184
neuron projection guidance GO:0097485 241 0.181
establishment of localization in cell GO:0051649 402 0.177
post embryonic appendage morphogenesis GO:0035120 385 0.176
histone acetylation GO:0016573 38 0.176
axonogenesis GO:0007409 290 0.172
chromatin mediated maintenance of transcription GO:0048096 7 0.171
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.169
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 13 0.168
gene silencing by rna GO:0031047 57 0.164
muscle organ development GO:0007517 127 0.164
mrna processing GO:0006397 104 0.162
macromolecule catabolic process GO:0009057 161 0.157
regulation of chromosome organization GO:0033044 64 0.157
apoptotic process GO:0006915 159 0.156
Mouse
reproductive structure development GO:0048608 74 0.155
Worm
regulation of multicellular organismal development GO:2000026 414 0.154
negative regulation of cellular catabolic process GO:0031330 34 0.152
autophagy GO:0006914 108 0.148
positive regulation of nervous system development GO:0051962 69 0.147
imaginal disc growth GO:0007446 37 0.143
cell migration GO:0016477 238 0.140
Mouse
positive regulation of programmed cell death GO:0043068 62 0.140
negative regulation of multicellular organismal process GO:0051241 142 0.139
carboxylic acid metabolic process GO:0019752 92 0.139
neuroblast proliferation GO:0007405 74 0.135
regulation of mrna processing GO:0050684 71 0.129
negative regulation of organelle organization GO:0010639 56 0.122
protein modification by small protein conjugation or removal GO:0070647 106 0.119
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 16 0.117
regulation of cellular catabolic process GO:0031329 157 0.117
cell cycle checkpoint GO:0000075 95 0.114
histone h4 k16 acetylation GO:0043984 4 0.114
chromatin remodeling GO:0006338 72 0.113
chromatin assembly GO:0031497 48 0.111
Yeast
dorsal ventral pattern formation GO:0009953 133 0.110
regulation of mitotic cell cycle phase transition GO:1901990 130 0.108
larval development GO:0002164 104 0.108
negative regulation of nucleic acid templated transcription GO:1903507 240 0.108
Human Yeast Mouse Rat
regulation of stem cell proliferation GO:0072091 40 0.106
gland development GO:0048732 191 0.106
Mouse
positive regulation of cell communication GO:0010647 250 0.105
compound eye development GO:0048749 307 0.103
regulation of transport GO:0051049 181 0.103
reproductive behavior GO:0019098 122 0.100
actin cytoskeleton organization GO:0030036 206 0.100
regulation of proteolysis GO:0030162 87 0.099
stem cell proliferation GO:0072089 88 0.098
tube morphogenesis GO:0035239 191 0.097
mitotic dna integrity checkpoint GO:0044774 75 0.095
regulation of organ growth GO:0046620 42 0.095
wing disc morphogenesis GO:0007472 344 0.094
mrna metabolic process GO:0016071 124 0.094
regulation of neuron projection development GO:0010975 69 0.094
cellular macromolecule catabolic process GO:0044265 136 0.093
somatic muscle development GO:0007525 66 0.091
immune system development GO:0002520 57 0.090
Mouse
appendage morphogenesis GO:0035107 397 0.089
cell fate specification GO:0001708 71 0.089
digestive tract morphogenesis GO:0048546 127 0.088
developmental programmed cell death GO:0010623 138 0.087
cellular response to organic substance GO:0071310 132 0.085
gonad morphogenesis GO:0035262 7 0.083
programmed cell death GO:0012501 257 0.080
Mouse
gene silencing by mirna GO:0035195 22 0.080
developmental pigmentation GO:0048066 68 0.078
response to abiotic stimulus GO:0009628 341 0.078
posttranscriptional gene silencing by rna GO:0035194 45 0.077
regulation of catabolic process GO:0009894 170 0.076
catabolic process GO:0009056 409 0.076
Human Yeast Mouse
protein catabolic process GO:0030163 101 0.075
translation GO:0006412 69 0.075
neuron maturation GO:0042551 31 0.074
negative regulation of protein metabolic process GO:0051248 85 0.074
negative regulation of cell communication GO:0010648 223 0.074
Human
male gamete generation GO:0048232 201 0.074
Rat
oocyte morphogenesis GO:0048601 3 0.073
organelle fission GO:0048285 340 0.070
Yeast
negative regulation of chromosome segregation GO:0051985 14 0.070
regulation of response to stress GO:0080134 200 0.070
organic acid metabolic process GO:0006082 103 0.069
alternative mrna splicing via spliceosome GO:0000380 60 0.068
signal transduction by phosphorylation GO:0023014 107 0.068
eggshell formation GO:0030703 105 0.067
regulation of organelle organization GO:0033043 196 0.066
ras protein signal transduction GO:0007265 88 0.066
negative regulation of nervous system development GO:0051961 92 0.066
chromosome condensation GO:0030261 41 0.063
morphogenesis of an epithelium GO:0002009 276 0.063
Mouse
purine nucleoside metabolic process GO:0042278 127 0.063
Human Yeast Mouse
maternal determination of dorsal ventral axis ovarian follicular epithelium soma encoded GO:0008071 1 0.062
negative regulation of programmed cell death GO:0043069 72 0.062
Mouse
regulation of cell proliferation involved in compound eye morphogenesis GO:2000495 2 0.061
positive regulation of signal transduction GO:0009967 223 0.060
oviposition GO:0018991 19 0.059
histone h2a acetylation GO:0043968 1 0.058
protein phosphorylation GO:0006468 169 0.058
mitotic nuclear division GO:0007067 213 0.058
negative regulation of chromatin silencing GO:0031936 9 0.057
positive regulation of neurogenesis GO:0050769 41 0.056
salivary gland development GO:0007431 162 0.056
positive regulation of cell differentiation GO:0045597 64 0.055
Yeast Mouse
epithelial cell fate determination open tracheal system GO:0007425 2 0.055
negative regulation of developmental process GO:0051093 201 0.055
regulation of erk1 and erk2 cascade GO:0070372 39 0.054
retina morphogenesis in camera type eye GO:0060042 2 0.053
peptidyl amino acid modification GO:0018193 105 0.053
endocytosis GO:0006897 310 0.053
negative regulation of nucleotide metabolic process GO:0045980 4 0.052
phosphorylation GO:0016310 294 0.052
rna splicing GO:0008380 83 0.051
regulation of canonical wnt signaling pathway GO:0060828 15 0.051
single organism biosynthetic process GO:0044711 206 0.051
multi organism reproductive behavior GO:0044705 121 0.051
larval lymph gland hemocyte differentiation GO:0035168 11 0.050
head development GO:0060322 135 0.050
Mouse
imaginal disc derived wing vein specification GO:0007474 48 0.050
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.050
positive regulation of proteolysis GO:0045862 52 0.049
circadian rhythm GO:0007623 105 0.049
cellular response to peptide GO:1901653 28 0.049
cell cell signaling involved in cell fate commitment GO:0045168 210 0.048
central nervous system development GO:0007417 201 0.048
Mouse
nucleosome positioning GO:0016584 3 0.048
Yeast
organic substance catabolic process GO:1901575 308 0.048
Human Yeast Mouse
regulation of cellular protein catabolic process GO:1903362 44 0.048
regulation of intracellular transport GO:0032386 64 0.048
instar larval development GO:0002168 55 0.047
g1 s transition of mitotic cell cycle GO:0000082 31 0.047
dendrite regeneration GO:0031104 2 0.047
negative regulation of rna metabolic process GO:0051253 251 0.047
Human Yeast Mouse Rat
meiotic nuclear envelope disassembly GO:0051078 2 0.047
compound eye morphogenesis GO:0001745 249 0.047
dna integrity checkpoint GO:0031570 81 0.047
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.046
regulation of response to gamma radiation GO:2001228 4 0.046
multicellular organismal aging GO:0010259 140 0.045
mrna splicing via spliceosome GO:0000398 73 0.045
ribonucleoside triphosphate catabolic process GO:0009203 108 0.044
Human Yeast Mouse
appendage development GO:0048736 401 0.044
response to lipid GO:0033993 38 0.044
regulation of mitotic sister chromatid separation GO:0010965 28 0.044
organ growth GO:0035265 56 0.043
tissue death GO:0016271 102 0.043
cellular macromolecule localization GO:0070727 220 0.042
regulation of dendrite development GO:0050773 37 0.042
organic substance transport GO:0071702 257 0.042
cellular response to oxygen containing compound GO:1901701 79 0.042
negative regulation of signaling GO:0023057 219 0.041
Human
regulation of organ morphogenesis GO:2000027 78 0.041
positive regulation of gene expression epigenetic GO:0045815 16 0.040
negative regulation of chromosome organization GO:2001251 19 0.040
negative regulation of cell death GO:0060548 81 0.040
Mouse
meiotic chromosome segregation GO:0045132 59 0.040
defense response to other organism GO:0098542 225 0.039
cell motility GO:0048870 251 0.039
Mouse
locomotor rhythm GO:0045475 56 0.039
positive regulation of cell cycle GO:0045787 43 0.039
negative regulation of neural precursor cell proliferation GO:2000178 27 0.039
regulation of programmed cell death GO:0043067 152 0.039
Mouse
tube development GO:0035295 244 0.039
eye development GO:0001654 323 0.039
Human Mouse
compound eye photoreceptor cell differentiation GO:0001751 140 0.038
cellular response to dna damage stimulus GO:0006974 223 0.038
Yeast
cytoplasmic transport GO:0016482 130 0.038
oocyte fate commitment GO:0048600 2 0.037
mitotic cell cycle checkpoint GO:0007093 88 0.037
camera type eye morphogenesis GO:0048593 2 0.037
regulation of mapk cascade GO:0043408 92 0.036
regulation of cellular amino acid metabolic process GO:0006521 0 0.036
embryonic pattern specification GO:0009880 174 0.036
chromosome segregation GO:0007059 157 0.036
Yeast
forebrain development GO:0030900 2 0.036
Mouse
regulation of cell differentiation GO:0045595 302 0.035
regulation of phosphorylation GO:0042325 147 0.035
regulation of phosphorus metabolic process GO:0051174 210 0.035
meiotic nuclear division GO:0007126 151 0.034
Yeast
neurological system process GO:0050877 358 0.034
oxoacid metabolic process GO:0043436 103 0.034
embryo development ending in birth or egg hatching GO:0009792 152 0.034
Mouse Worm
salivary gland morphogenesis GO:0007435 145 0.034
tissue morphogenesis GO:0048729 297 0.034
Mouse
methylation GO:0032259 47 0.034
Mouse
neuron remodeling GO:0016322 29 0.034
regulation of histone deacetylation GO:0031063 2 0.034
meiotic spindle checkpoint GO:0044779 1 0.033
ribonucleotide catabolic process GO:0009261 109 0.033
Human Yeast Mouse
positive regulation of intracellular signal transduction GO:1902533 116 0.033
regulation of chromosome segregation GO:0051983 32 0.033
regulation of mrna metabolic process GO:1903311 72 0.033
developmental growth GO:0048589 280 0.033
Mouse
histone methylation GO:0016571 40 0.033
humoral immune response GO:0006959 117 0.033
circadian behavior GO:0048512 76 0.032
biological adhesion GO:0022610 138 0.032
Yeast
small molecule metabolic process GO:0044281 305 0.032
Human Yeast Mouse
somatic stem cell maintenance GO:0035019 14 0.032
sensory organ precursor cell division GO:0045035 10 0.032
gland morphogenesis GO:0022612 145 0.032
regulation of ras protein signal transduction GO:0046578 93 0.032
regulation of small gtpase mediated signal transduction GO:0051056 93 0.031
chromatin remodeling at centromere GO:0031055 3 0.031
Yeast
protein processing GO:0016485 68 0.031
protein import GO:0017038 55 0.031
single organism catabolic process GO:0044712 228 0.031
Human Yeast Mouse
nitrogen compound transport GO:0071705 85 0.030
negative regulation of apoptotic process GO:0043066 63 0.030
Mouse
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 2 0.030
regulation of protein metabolic process GO:0051246 256 0.030
negative regulation of terminal cell fate specification open tracheal system GO:0035155 2 0.029
neuron recognition GO:0008038 101 0.029
gastrulation GO:0007369 70 0.029
dna methylation on cytosine GO:0032776 1 0.029
Mouse
negative regulation of developmental pigmentation GO:0048086 1 0.028
cellular nitrogen compound catabolic process GO:0044270 165 0.028
Human Yeast Mouse
secretion GO:0046903 109 0.028
negative regulation of response to stimulus GO:0048585 258 0.028
Human
hematopoietic or lymphoid organ development GO:0048534 57 0.027
Mouse
nucleobase containing compound catabolic process GO:0034655 165 0.027
Human Yeast Mouse
response to ecdysone GO:0035075 34 0.027
establishment of organelle localization GO:0051656 122 0.026
response to sterol GO:0036314 34 0.026
phagocytosis GO:0006909 215 0.026
cellular amino acid metabolic process GO:0006520 61 0.026
regulation of protein stability GO:0031647 43 0.026
internal peptidyl lysine acetylation GO:0018393 38 0.026
positive regulation of cellular protein catabolic process GO:1903364 24 0.026
dendrite guidance GO:0070983 21 0.025
photoreceptor cell development GO:0042461 96 0.025
histone deubiquitination GO:0016578 8 0.025
response to other organism GO:0051707 293 0.025
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 17 0.025
cell division GO:0051301 248 0.025
mitochondrial membrane organization GO:0007006 3 0.025
neuron fate commitment GO:0048663 50 0.025
regulation of cellular response to stress GO:0080135 89 0.025
regulation of intracellular signal transduction GO:1902531 236 0.025
r3 r4 cell differentiation GO:0048056 12 0.025
intracellular protein transport GO:0006886 104 0.025
g2 dna damage checkpoint GO:0031572 69 0.024
regulation of multi organism process GO:0043900 131 0.024
Human Yeast
negative regulation of protein catabolic process GO:0042177 17 0.024
histone h4 acetylation involved in response to dna damage stimulus GO:2000776 1 0.024
cell type specific apoptotic process GO:0097285 38 0.024
cellular protein catabolic process GO:0044257 83 0.024
meiotic cell cycle GO:0051321 171 0.024
Yeast
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.023
dna templated transcriptional start site selection GO:0001173 1 0.023
axis specification GO:0009798 167 0.023
regulation of cytoplasmic transport GO:1903649 47 0.023
compound eye photoreceptor development GO:0042051 78 0.023
intracellular signal transduction GO:0035556 300 0.023
negative regulation of gtpase activity GO:0034260 1 0.023
regulation of sister chromatid segregation GO:0033045 28 0.023
hindgut development GO:0061525 58 0.023
histolysis GO:0007559 102 0.023
negative regulation of filopodium assembly GO:0051490 3 0.023
negative regulation of mrna 3 end processing GO:0031441 3 0.022
regulation of cellular component biogenesis GO:0044087 201 0.022
positive regulation of multicellular organismal process GO:0051240 143 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.022
positive regulation of signaling GO:0023056 243 0.022
defense response to bacterium GO:0042742 178 0.022
notch signaling pathway GO:0007219 120 0.021
cellular response to chemical stimulus GO:0070887 199 0.021
regulation of developmental growth GO:0048638 174 0.021
regulation of ran gtpase activity GO:0032316 1 0.021
hemopoiesis GO:0030097 46 0.021
Mouse
mitotic dna damage checkpoint GO:0044773 74 0.021
nucleotide catabolic process GO:0009166 109 0.021
Human Yeast Mouse
cellular response to organic cyclic compound GO:0071407 32 0.021
positive regulation of cell development GO:0010720 61 0.021
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.021
regulation of cell growth GO:0001558 43 0.021
Human
regulation of mrna splicing via spliceosome GO:0048024 64 0.020
receptor mediated endocytosis GO:0006898 21 0.020
intrinsic apoptotic signaling pathway GO:0097193 16 0.020
negative regulation of rho gtpase activity GO:0034259 1 0.020
organic cyclic compound catabolic process GO:1901361 168 0.020
Human Yeast Mouse
regulation of nucleocytoplasmic transport GO:0046822 35 0.020
regulation of sister chromatid cohesion GO:0007063 2 0.020
negative regulation of dna templated transcription initiation GO:2000143 1 0.020
intracellular transport GO:0046907 228 0.019
negative regulation of pigment cell differentiation GO:0050941 1 0.019
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.019
response to nutrient levels GO:0031667 114 0.019
Yeast
central nervous system neuron differentiation GO:0021953 8 0.019
syncytial blastoderm mitotic cell cycle GO:0035186 21 0.019
axon development GO:0061564 297 0.019
establishment of ommatidial planar polarity GO:0042067 49 0.019
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.019
mesenchymal cell development GO:0014031 1 0.018
positive regulation of transcription involved in g2 m transition of mitotic cell cycle GO:0090282 1 0.018
protein complex assembly GO:0006461 200 0.018
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.018
anterior posterior axis specification follicular epithelium GO:0030714 2 0.018
regulation of immune system process GO:0002682 176 0.018
lipid localization GO:0010876 54 0.018
positive regulation of notch signaling pathway GO:0045747 34 0.018
regulation of hematopoietic stem cell differentiation GO:1902036 1 0.018
blastoderm segmentation GO:0007350 159 0.018
meiotic dna repair synthesis GO:0000711 3 0.018
regulation of map kinase activity GO:0043405 17 0.017
border follicle cell delamination GO:0030709 3 0.017
base excision repair GO:0006284 2 0.017
Yeast
trichome differentiation GO:0010026 3 0.017
response to ketone GO:1901654 34 0.017
stem cell differentiation GO:0048863 117 0.017
Mouse
erk1 and erk2 cascade GO:0070371 39 0.017
regulation of anatomical structure morphogenesis GO:0022603 242 0.017
regulation of tube size GO:0035150 46 0.017
positive regulation of growth GO:0045927 75 0.017
Yeast
macromolecule deacylation GO:0098732 11 0.017
negative regulation of molecular function GO:0044092 51 0.017

brm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.177
disease of cellular proliferation DOID:14566 0 0.177
organ system cancer DOID:0050686 0 0.177
brachydactyly DOID:0050581 0 0.105
bone development disease DOID:0080006 0 0.105
bone disease DOID:0080001 0 0.105
disease of anatomical entity DOID:7 0 0.105
dysostosis DOID:1934 0 0.105
musculoskeletal system disease DOID:17 0 0.105
connective tissue disease DOID:65 0 0.105
artery disease DOID:0050828 0 0.017
vascular disease DOID:178 0 0.017
cardiovascular system disease DOID:1287 0 0.017
aortic disease DOID:520 0 0.017
leopard syndrome DOID:14291 0 0.017
nervous system benign neoplasm DOID:0060115 0 0.017
organ system benign neoplasm DOID:0060085 0 0.017
neuroma DOID:2001 0 0.017
neurilemmoma DOID:3192 0 0.017
benign neoplasm DOID:0060072 0 0.017
neurilemmomatosis DOID:3204 0 0.017