Drosophila melanogaster

0 known processes

eIF5B (Dmel_CG10840)

CG10840 gene product from transcript CG10840-RB

(Aliases: anon-WO0118547.362,cIF2,IF2,CG14970,dIF2,A1,Dmel\CG10840,yIF2,CG10840)

eIF5B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of localization in cell GO:0051649 402 0.229
cellular protein modification process GO:0006464 438 0.168
nuclear division GO:0000280 332 0.138
positive regulation of biosynthetic process GO:0009891 316 0.131
intracellular signal transduction GO:0035556 300 0.105
protein modification by small protein conjugation or removal GO:0070647 106 0.096
positive regulation of gene expression GO:0010628 290 0.094
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.088
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.083
chromatin modification GO:0016568 147 0.074
intracellular transport GO:0046907 228 0.070
eye morphogenesis GO:0048592 260 0.069
negative regulation of gene expression GO:0010629 387 0.064
compound eye morphogenesis GO:0001745 249 0.063
positive regulation of cellular biosynthetic process GO:0031328 316 0.062
protein modification process GO:0036211 438 0.061
localization of cell GO:0051674 257 0.061
positive regulation of nucleic acid templated transcription GO:1903508 266 0.059
mitotic nuclear division GO:0007067 213 0.058
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.057
eye development GO:0001654 323 0.054
response to other organism GO:0051707 293 0.054
positive regulation of response to stimulus GO:0048584 323 0.053
regulation of multicellular organismal development GO:2000026 414 0.050
transcription from rna polymerase ii promoter GO:0006366 368 0.050
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.049
negative regulation of rna biosynthetic process GO:1902679 240 0.049
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.048
chromosome organization GO:0051276 360 0.048
positive regulation of rna biosynthetic process GO:1902680 266 0.047
organelle fission GO:0048285 340 0.047
spermatogenesis GO:0007283 200 0.046
defense response GO:0006952 300 0.046
sensory organ morphogenesis GO:0090596 260 0.046
organonitrogen compound metabolic process GO:1901564 318 0.044
regulation of intracellular signal transduction GO:1902531 236 0.043
catabolic process GO:0009056 409 0.042
negative regulation of cellular metabolic process GO:0031324 382 0.041
negative regulation of transcription dna templated GO:0045892 237 0.040
positive regulation of transcription dna templated GO:0045893 266 0.040
cytoplasmic transport GO:0016482 130 0.039
negative regulation of rna metabolic process GO:0051253 251 0.039
negative regulation of nucleic acid templated transcription GO:1903507 240 0.039
cellular macromolecule catabolic process GO:0044265 136 0.039
growth GO:0040007 359 0.037
modification dependent macromolecule catabolic process GO:0043632 79 0.037
compound eye development GO:0048749 307 0.037
jak stat cascade GO:0007259 49 0.037
ubiquitin dependent protein catabolic process GO:0006511 78 0.037
regulation of cellular component biogenesis GO:0044087 201 0.036
positive regulation of cell communication GO:0010647 250 0.034
segmentation GO:0035282 207 0.033
positive regulation of rna metabolic process GO:0051254 271 0.033
regulation of cell cycle GO:0051726 291 0.033
single organism intracellular transport GO:1902582 207 0.033
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.032
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.032
protein localization GO:0008104 284 0.032
rrna processing GO:0006364 3 0.031
positive regulation of macromolecule metabolic process GO:0010604 405 0.030
aging GO:0007568 143 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.030
single organism catabolic process GO:0044712 228 0.030
body morphogenesis GO:0010171 2 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.030
developmental growth GO:0048589 280 0.029
male gamete generation GO:0048232 201 0.029
regulation of catalytic activity GO:0050790 185 0.029
small molecule metabolic process GO:0044281 305 0.029
proteolysis GO:0006508 192 0.028
organonitrogen compound biosynthetic process GO:1901566 117 0.027
small gtpase mediated signal transduction GO:0007264 88 0.027
dna repair GO:0006281 54 0.027
organic substance catabolic process GO:1901575 308 0.027
cell cycle phase transition GO:0044770 140 0.027
carbohydrate derivative catabolic process GO:1901136 118 0.027
dna metabolic process GO:0006259 227 0.026
mitotic spindle elongation GO:0000022 81 0.026
carbohydrate derivative metabolic process GO:1901135 217 0.026
negative regulation of cellular biosynthetic process GO:0031327 277 0.026
regulation of cell differentiation GO:0045595 302 0.026
organic substance transport GO:0071702 257 0.025
cellular response to dna damage stimulus GO:0006974 223 0.025
cellular catabolic process GO:0044248 372 0.025
positive regulation of signaling GO:0023056 243 0.025
vesicle mediated transport GO:0016192 381 0.025
modification dependent protein catabolic process GO:0019941 78 0.024
regulation of gene expression epigenetic GO:0040029 128 0.024
histone modification GO:0016570 106 0.024
gene silencing by rna GO:0031047 57 0.024
developmental maturation GO:0021700 172 0.023
gene silencing GO:0016458 138 0.023
eye photoreceptor cell differentiation GO:0001754 145 0.023
protein modification by small protein conjugation GO:0032446 79 0.023
regulation of developmental growth GO:0048638 174 0.023
columnar cuboidal epithelial cell development GO:0002066 249 0.023
compound eye photoreceptor cell differentiation GO:0001751 140 0.023
rna interference GO:0016246 27 0.023
macromolecule catabolic process GO:0009057 161 0.023
gland development GO:0048732 191 0.023
wing disc morphogenesis GO:0007472 344 0.022
purine nucleoside metabolic process GO:0042278 127 0.022
regulation of catabolic process GO:0009894 170 0.022
oocyte development GO:0048599 124 0.022
appendage development GO:0048736 401 0.022
ras protein signal transduction GO:0007265 88 0.022
multicellular organismal aging GO:0010259 140 0.022
innate immune response GO:0045087 144 0.022
defense response to bacterium GO:0042742 178 0.021
defense response to other organism GO:0098542 225 0.021
nucleotide metabolic process GO:0009117 161 0.021
protein ubiquitination GO:0016567 70 0.021
glycosyl compound catabolic process GO:1901658 112 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.021
posttranscriptional gene silencing GO:0016441 46 0.021
death GO:0016265 284 0.021
oocyte differentiation GO:0009994 145 0.021
connective tissue development GO:0061448 3 0.020
regulation of oocyte development GO:0060281 27 0.020
oocyte construction GO:0007308 112 0.020
positive regulation of signal transduction GO:0009967 223 0.020
spindle elongation GO:0051231 83 0.020
defense response to gram negative bacterium GO:0050829 94 0.020
regulation of response to stress GO:0080134 200 0.019
axon development GO:0061564 297 0.019
ribonucleoside triphosphate catabolic process GO:0009203 108 0.019
stem cell maintenance GO:0019827 67 0.019
spindle organization GO:0007051 253 0.019
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.019
regulation of small gtpase mediated signal transduction GO:0051056 93 0.019
chromatin organization GO:0006325 207 0.018
regulation of defense response GO:0031347 102 0.018
regulation of embryonic development GO:0045995 68 0.018
organophosphate catabolic process GO:0046434 112 0.018
epithelial cell differentiation GO:0030855 322 0.018
cellular macromolecular complex assembly GO:0034622 153 0.018
regulation of mitotic cell cycle phase transition GO:1901990 130 0.018
translation GO:0006412 69 0.018
positive regulation of proteolysis GO:0045862 52 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
regulation of molecular function GO:0065009 217 0.017
ribonucleotide catabolic process GO:0009261 109 0.017
central nervous system development GO:0007417 201 0.017
post embryonic appendage morphogenesis GO:0035120 385 0.017
posttranscriptional gene silencing by rna GO:0035194 45 0.017
single organism biosynthetic process GO:0044711 206 0.017
embryonic pattern specification GO:0009880 174 0.017
cellularization GO:0007349 90 0.017
cell death GO:0008219 279 0.017
regulation of apoptotic process GO:0042981 130 0.017
regulation of protein complex assembly GO:0043254 42 0.016
cell motility GO:0048870 251 0.016
regulation of hydrolase activity GO:0051336 97 0.016
negative regulation of biosynthetic process GO:0009890 277 0.016
head development GO:0060322 135 0.016
photoreceptor cell development GO:0042461 96 0.016
protein transport GO:0015031 155 0.016
regulation of proteolysis GO:0030162 87 0.016
regulation of multi organism process GO:0043900 131 0.016
regulation of mitotic cell cycle GO:0007346 190 0.016
phosphorylation GO:0016310 294 0.016
covalent chromatin modification GO:0016569 106 0.016
posttranscriptional regulation of gene expression GO:0010608 145 0.015
retina development in camera type eye GO:0060041 4 0.015
determination of adult lifespan GO:0008340 137 0.015
positive regulation of cellular protein metabolic process GO:0032270 118 0.015
ribonucleoside catabolic process GO:0042454 112 0.015
regulation of protein metabolic process GO:0051246 256 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.015
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.015
establishment or maintenance of cell polarity GO:0007163 167 0.015
cellular amino acid metabolic process GO:0006520 61 0.015
response to abiotic stimulus GO:0009628 341 0.015
negative regulation of developmental process GO:0051093 201 0.015
regulation of growth GO:0040008 233 0.015
ribonucleoside triphosphate metabolic process GO:0009199 119 0.015
positive regulation of peptidase activity GO:0010952 29 0.015
germarium derived egg chamber formation GO:0007293 101 0.015
regulation of cell cycle process GO:0010564 181 0.014
nucleoside triphosphate metabolic process GO:0009141 120 0.014
single organism cellular localization GO:1902580 180 0.014
synapse organization GO:0050808 196 0.014
programmed cell death GO:0012501 257 0.014
regulation of notch signaling pathway GO:0008593 100 0.014
oocyte anterior posterior axis specification GO:0007314 72 0.014
anterior posterior axis specification GO:0009948 109 0.014
phagocytosis GO:0006909 215 0.014
heterocycle catabolic process GO:0046700 166 0.014
purine nucleoside triphosphate catabolic process GO:0009146 108 0.014
skeletal muscle organ development GO:0060538 48 0.014
regulation of ras protein signal transduction GO:0046578 93 0.014
organic acid metabolic process GO:0006082 103 0.014
maternal determination of anterior posterior axis embryo GO:0008358 74 0.014
protein complex assembly GO:0006461 200 0.014
axis specification GO:0009798 167 0.014
negative regulation of response to stimulus GO:0048585 258 0.014
protein modification by small protein removal GO:0070646 28 0.014
regulation of mrna metabolic process GO:1903311 72 0.014
cell cell signaling involved in cell fate commitment GO:0045168 210 0.014
extracellular structure organization GO:0043062 46 0.014
negative regulation of programmed cell death GO:0043069 72 0.013
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 8 0.013
protein complex biogenesis GO:0070271 201 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.013
protein catabolic process GO:0030163 101 0.013
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
cell maturation GO:0048469 144 0.013
regulation of cell morphogenesis GO:0022604 163 0.013
antimicrobial humoral response GO:0019730 99 0.013
gtp catabolic process GO:0006184 72 0.013
rna splicing GO:0008380 83 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.013
cellular protein catabolic process GO:0044257 83 0.013
rubidium ion transport GO:0035826 1 0.013
nucleoside catabolic process GO:0009164 112 0.013
reproductive structure development GO:0048608 74 0.013
chromatin remodeling GO:0006338 72 0.013
embryonic axis specification GO:0000578 107 0.012
stem cell development GO:0048864 79 0.012
immune response GO:0006955 246 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
eye antennal disc morphogenesis GO:0007455 34 0.012
ameboidal type cell migration GO:0001667 151 0.012
aromatic compound catabolic process GO:0019439 166 0.012
ncrna processing GO:0034470 30 0.012
purine ribonucleoside metabolic process GO:0046128 127 0.012
nucleotide catabolic process GO:0009166 109 0.012
cell migration GO:0016477 238 0.012
nuclear body organization GO:0030575 6 0.012
regulation of anatomical structure size GO:0090066 163 0.012
carboxylic acid metabolic process GO:0019752 92 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
epithelial cell development GO:0002064 274 0.012
humoral immune response GO:0006959 117 0.012
vesicle organization GO:0016050 44 0.012
o glycan processing GO:0016266 3 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
tripartite regional subdivision GO:0007351 103 0.012
pole plasm rna localization GO:0007316 52 0.012
purine containing compound metabolic process GO:0072521 155 0.012
response to biotic stimulus GO:0009607 294 0.012
monocarboxylic acid transport GO:0015718 3 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
positive regulation of growth GO:0045927 75 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.011
chromosome segregation GO:0007059 157 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.011
pole plasm mrna localization GO:0019094 49 0.011
ncrna metabolic process GO:0034660 43 0.011
nucleus organization GO:0006997 45 0.011
membrane organization GO:0061024 112 0.011
anterior posterior pattern specification GO:0009952 136 0.011
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
protein maturation GO:0051604 71 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
cytoplasmic translation GO:0002181 0 0.011
intracellular mrna localization GO:0008298 66 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
positive regulation of nucleoside metabolic process GO:0045979 47 0.011
gtp metabolic process GO:0046039 72 0.011
neurological system process GO:0050877 358 0.011
negative regulation of signal transduction GO:0009968 206 0.011
positive regulation of protein catabolic process GO:0045732 34 0.011
tissue morphogenesis GO:0048729 297 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.011
response to ecdysone GO:0035075 34 0.011
negative regulation of cell communication GO:0010648 223 0.011
imaginal disc derived leg morphogenesis GO:0007480 80 0.011
regulation of cysteine type endopeptidase activity GO:2000116 27 0.011
purine containing compound catabolic process GO:0072523 112 0.010
regulation of cell cycle phase transition GO:1901987 130 0.010
regulation of cellular component size GO:0032535 98 0.010
spindle assembly GO:0051225 80 0.010
nucleoside metabolic process GO:0009116 127 0.010
purine nucleotide catabolic process GO:0006195 109 0.010
tissue death GO:0016271 102 0.010
ovarian follicle cell migration GO:0007297 121 0.010
histolysis GO:0007559 102 0.010
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.010
nucleoside triphosphate catabolic process GO:0009143 108 0.010
nuclear export GO:0051168 24 0.010
regulation of nervous system development GO:0051960 248 0.010
single organism membrane budding GO:1902591 2 0.010
regulation of gtp catabolic process GO:0033124 44 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
myotube cell development GO:0014904 3 0.010
cellular nitrogen compound catabolic process GO:0044270 165 0.010

eIF5B disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.091
nervous system disease DOID:863 0 0.039
central nervous system disease DOID:331 0 0.034
neurodegenerative disease DOID:1289 0 0.034
urinary system disease DOID:18 0 0.014
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
sensory system disease DOID:0050155 0 0.012
disease of metabolism DOID:0014667 0 0.011