Drosophila melanogaster

85 known processes

mod(mdg4) (Dmel_CG32491)

modifier of mdg4

(Aliases: E(var)3-93D,E-var(3)1,E-var(3)3,CG7836,CG15802,mod(gypsy),mnm,mnn,CG7859,E(var)129,mdg4,E-(var)3-93D,mod2.2,pf-2,l(3)03852,CG18151,E(var)93D,Doom,MOD(MDG4)56.3,BcDNA:SD03001,mod(mdg-4),CG15500,CG15501,Mod[mdg4],Mod(mdg4)67.2,Mod(mdg4)-67.2,Mod(mdg)4,CG32491,doom,BcDNA:GH07769,Mod(mdg4),CG8076,l(3)j2B7,Dmel\CG32491,bpd,Mod(mdg4)2.2,mod[mdg4],mod(mdg4)67.2,mod,mod(mdg4)-67.2,l(3)L3101,MOD(MDG4))

mod(mdg4) biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic cell cycle process GO:1903046 132 1.000
meiotic nuclear division GO:0007126 151 1.000
nuclear division GO:0000280 332 0.999
chromosome organization GO:0051276 360 0.999
positive regulation of transcription dna templated GO:0045893 266 0.997
Fly
regulation of chromatin silencing GO:0031935 36 0.995
Fly
organelle fission GO:0048285 340 0.994
male meiosis GO:0007140 52 0.990
meiotic cell cycle GO:0051321 171 0.990
meiotic chromosome segregation GO:0045132 59 0.988
dendrite morphogenesis GO:0048813 199 0.964
Fly
chromatin organization GO:0006325 207 0.962
dendrite development GO:0016358 204 0.925
Fly
negative regulation of cellular component organization GO:0051129 108 0.922
regulation of gene silencing GO:0060968 63 0.897
Fly
chromatin silencing GO:0006342 76 0.876
Fly
chromosome segregation GO:0007059 157 0.867
post embryonic appendage morphogenesis GO:0035120 385 0.842
Fly
histone h4 acetylation GO:0043967 13 0.833
chromatin modification GO:0016568 147 0.796
histone acetylation GO:0016573 38 0.755
negative regulation of gene expression GO:0010629 387 0.713
Fly
chromatin assembly or disassembly GO:0006333 52 0.706
histone modification GO:0016570 106 0.681
covalent chromatin modification GO:0016569 106 0.631
reproductive structure development GO:0048608 74 0.592
Fly
positive regulation of nucleic acid templated transcription GO:1903508 266 0.578
Fly
regulation of gene expression epigenetic GO:0040029 128 0.561
Fly
neuron projection guidance GO:0097485 241 0.542
Fly
regulation of rna splicing GO:0043484 69 0.542
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.476
Fly
negative regulation of nervous system development GO:0051961 92 0.473
peptidyl lysine acetylation GO:0018394 39 0.452
cytoskeleton dependent cytokinesis GO:0061640 81 0.434
male meiosis chromosome segregation GO:0007060 10 0.412
cell motility GO:0048870 251 0.406
organelle assembly GO:0070925 198 0.374
histone h3 acetylation GO:0043966 11 0.373
rna splicing GO:0008380 83 0.351
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.346
Fly
growth GO:0040007 359 0.341
Fly
peptidyl lysine modification GO:0018205 57 0.325
taxis GO:0042330 304 0.322
Fly
internal peptidyl lysine acetylation GO:0018393 38 0.322
spindle organization GO:0007051 253 0.306
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.303
Fly
protein acetylation GO:0006473 39 0.299
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.295
Fly
regulation of multicellular organismal development GO:2000026 414 0.275
Fly
positive regulation of gene expression GO:0010628 290 0.272
Fly
photoreceptor cell differentiation GO:0046530 170 0.257
Fly
negative regulation of organelle organization GO:0010639 56 0.257
sex differentiation GO:0007548 81 0.255
Fly
positive regulation of cellular biosynthetic process GO:0031328 316 0.250
Fly
male gamete generation GO:0048232 201 0.249
Fly
cellular macromolecular complex assembly GO:0034622 153 0.240
chromatin remodeling GO:0006338 72 0.239
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.237
Fly
mrna metabolic process GO:0016071 124 0.229
negative regulation of biosynthetic process GO:0009890 277 0.228
Fly
mitotic cell cycle phase transition GO:0044772 138 0.225
positive regulation of rna metabolic process GO:0051254 271 0.209
Fly
cell proliferation GO:0008283 299 0.207
positive regulation of macromolecule metabolic process GO:0010604 405 0.207
Fly
axonogenesis GO:0007409 290 0.200
Fly
meiosis i GO:0007127 59 0.198
posttranscriptional gene silencing GO:0016441 46 0.191
sister chromatid segregation GO:0000819 92 0.187
regulation of cellular amino acid metabolic process GO:0006521 0 0.183
negative regulation of cellular biosynthetic process GO:0031327 277 0.162
Fly
axon development GO:0061564 297 0.161
Fly
lateral inhibition GO:0046331 206 0.159
dna packaging GO:0006323 91 0.158
eye photoreceptor cell differentiation GO:0001754 145 0.158
Fly
cellular protein modification process GO:0006464 438 0.146
microtubule polymerization or depolymerization GO:0031109 39 0.142
negative regulation of cellular metabolic process GO:0031324 382 0.142
Fly
positive regulation of cellular component organization GO:0051130 156 0.135
photoreceptor cell development GO:0042461 96 0.133
Fly
regulation of meiotic cell cycle GO:0051445 9 0.128
cell maturation GO:0048469 144 0.127
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.125
Fly
negative regulation of chromatin silencing GO:0031936 9 0.122
regulation of cell morphogenesis GO:0022604 163 0.122
Fly
protein catabolic process GO:0030163 101 0.115
regulation of chromatin modification GO:1903308 28 0.114
cell cell signaling involved in cell fate commitment GO:0045168 210 0.114
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.113
Fly
internal protein amino acid acetylation GO:0006475 38 0.109
positive regulation of biosynthetic process GO:0009891 316 0.109
Fly
neurological system process GO:0050877 358 0.107
Fly
eggshell chorion assembly GO:0007306 66 0.106
Fly
cell fate specification GO:0001708 71 0.105
Fly
protein acylation GO:0043543 42 0.104
negative regulation of response to stimulus GO:0048585 258 0.104
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.103
Fly
programmed cell death GO:0012501 257 0.100
regulation of mrna splicing via spliceosome GO:0048024 64 0.099
macromolecule catabolic process GO:0009057 161 0.096
regulation of cell cycle phase transition GO:1901987 130 0.095
spermatogenesis GO:0007283 200 0.092
Fly
gene silencing GO:0016458 138 0.092
Fly
posttranscriptional regulation of gene expression GO:0010608 145 0.091
regulation of protein complex disassembly GO:0043244 29 0.088
regionalization GO:0003002 416 0.087
Fly
negative regulation of neurogenesis GO:0050768 53 0.083
regulation of molecular function GO:0065009 217 0.081
Fly
cellular amine metabolic process GO:0044106 12 0.080
regulation of meiosis GO:0040020 3 0.079
chromosome condensation GO:0030261 41 0.077
regulation of developmental growth GO:0048638 174 0.077
brain morphogenesis GO:0048854 16 0.076
Fly
dna recombination GO:0006310 32 0.076
meiotic cytokinesis GO:0033206 33 0.072
regulation of neuron projection development GO:0010975 69 0.072
compound eye photoreceptor cell differentiation GO:0001751 140 0.072
Fly
regulation of cellular amine metabolic process GO:0033238 3 0.071
imaginal disc derived appendage development GO:0048737 399 0.068
Fly
muscle structure development GO:0061061 224 0.067
regulation of cell cycle process GO:0010564 181 0.066
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.065
negative regulation of developmental process GO:0051093 201 0.064
regulation of organ morphogenesis GO:2000027 78 0.063
Fly
embryo development ending in birth or egg hatching GO:0009792 152 0.063
Fly
modification dependent macromolecule catabolic process GO:0043632 79 0.059
macromolecular complex assembly GO:0065003 256 0.059
Fly
positive regulation of rna biosynthetic process GO:1902680 266 0.057
Fly
death GO:0016265 284 0.057
protein modification process GO:0036211 438 0.057
negative regulation of gene expression epigenetic GO:0045814 77 0.056
Fly
positive regulation of signaling GO:0023056 243 0.055
eye photoreceptor cell development GO:0042462 81 0.055
Fly
regulation of mrna metabolic process GO:1903311 72 0.053
regulation of cell cycle GO:0051726 291 0.053
reproductive system development GO:0061458 74 0.053
Fly
regulation of neurogenesis GO:0050767 158 0.053
regulation of chromatin organization GO:1902275 32 0.052
regulation of embryonic development GO:0045995 68 0.052
Fly
negative regulation of rna metabolic process GO:0051253 251 0.050
Fly
negative regulation of meiotic cell cycle GO:0051447 2 0.050
apoptotic process GO:0006915 159 0.049
mrna splicing via spliceosome GO:0000398 73 0.049
negative regulation of rna biosynthetic process GO:1902679 240 0.049
Fly
peptidyl amino acid modification GO:0018193 105 0.048
protein complex disassembly GO:0043241 36 0.048
cellular protein complex assembly GO:0043623 71 0.048
appendage morphogenesis GO:0035107 397 0.047
Fly
negative regulation of cell differentiation GO:0045596 143 0.047
establishment of rna localization GO:0051236 47 0.047
negative regulation of cell communication GO:0010648 223 0.046
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.045
regulation of cellular component biogenesis GO:0044087 201 0.045
chemotaxis GO:0006935 249 0.045
Fly
dorsal ventral pattern formation GO:0009953 133 0.045
ubiquitin dependent protein catabolic process GO:0006511 78 0.043
regulation of cellular ketone metabolic process GO:0010565 3 0.042
localization of cell GO:0051674 257 0.042
proteolysis GO:0006508 192 0.042
cuticle development GO:0042335 86 0.040
Fly
regulation of anatomical structure size GO:0090066 163 0.040
Fly
sensory organ morphogenesis GO:0090596 260 0.040
Fly
cellular protein catabolic process GO:0044257 83 0.040
developmental programmed cell death GO:0010623 138 0.039
Fly
dosage compensation GO:0007549 16 0.039
Fly
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.039
negative regulation of cell development GO:0010721 62 0.039
regulation of localization GO:0032879 275 0.038
cell death GO:0008219 279 0.038
positive regulation of multicellular organismal process GO:0051240 143 0.037
cell division GO:0051301 248 0.036
chromatin assembly GO:0031497 48 0.035
Fly
meiosis ii GO:0007135 23 0.035
small molecule metabolic process GO:0044281 305 0.035
positive regulation of cell cycle GO:0045787 43 0.035
positive regulation of response to stimulus GO:0048584 323 0.034
female germ line cyst formation GO:0048135 42 0.034
ameboidal type cell migration GO:0001667 151 0.033
Fly
posttranscriptional gene silencing by rna GO:0035194 45 0.033
positive regulation of developmental growth GO:0048639 62 0.032
positive regulation of cell cycle process GO:0090068 28 0.032
response to abiotic stimulus GO:0009628 341 0.032
transcription from rna polymerase ii promoter GO:0006366 368 0.031
Fly
tube morphogenesis GO:0035239 191 0.031
Fly
epithelial tube morphogenesis GO:0060562 88 0.031
Fly
actin cytoskeleton organization GO:0030036 206 0.031
amine metabolic process GO:0009308 12 0.031
cell cycle phase transition GO:0044770 140 0.029
imaginal disc derived wing morphogenesis GO:0007476 337 0.029
Fly
oocyte differentiation GO:0009994 145 0.029
regulation of compound eye cone cell fate specification GO:0042682 4 0.028
Fly
anterior posterior axis specification GO:0009948 109 0.027
Fly
regulation of cell proliferation GO:0042127 163 0.027
cellular component disassembly GO:0022411 46 0.027
dna conformation change GO:0071103 105 0.027
gonad development GO:0008406 50 0.026
Fly
body morphogenesis GO:0010171 2 0.025
compound eye development GO:0048749 307 0.025
Fly
appendage development GO:0048736 401 0.025
Fly
reproductive behavior GO:0019098 122 0.025
genitalia development GO:0048806 26 0.025
positive regulation of cellular amine metabolic process GO:0033240 0 0.025
regulation of cell fate commitment GO:0010453 29 0.024
Fly
eye morphogenesis GO:0048592 260 0.024
Fly
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.024
proteasomal protein catabolic process GO:0010498 59 0.024
negative regulation of transcription factor import into nucleus GO:0042992 4 0.023
regulation of protein complex assembly GO:0043254 42 0.023
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.023
mitotic chromosome condensation GO:0007076 22 0.023
axon guidance GO:0007411 233 0.023
Fly
establishment of tissue polarity GO:0007164 87 0.022
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.022
ribonucleoprotein complex assembly GO:0022618 23 0.022
dendrite regeneration GO:0031104 2 0.022
mrna processing GO:0006397 104 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.022
positive regulation of molecular function GO:0044093 136 0.022
Fly
oocyte morphogenesis GO:0048601 3 0.022
negative regulation of developmental growth GO:0048640 64 0.022
negative regulation of multicellular organismal process GO:0051241 142 0.022
regulation of chromosome organization GO:0033044 64 0.021
mitotic dna damage checkpoint GO:0044773 74 0.021
regulation of neuron differentiation GO:0045664 103 0.021
compound eye photoreceptor development GO:0042051 78 0.020
Fly
ovulation cycle GO:0042698 1 0.020
notch signaling pathway GO:0007219 120 0.020
cellular macromolecule catabolic process GO:0044265 136 0.020
positive regulation of developmental process GO:0051094 143 0.020
r1 r6 cell differentiation GO:0048052 4 0.020
Fly
tracheal outgrowth open tracheal system GO:0007426 18 0.019
Fly
regulation of cellular protein metabolic process GO:0032268 243 0.019
modification dependent protein catabolic process GO:0019941 78 0.019
maternal determination of dorsal ventral axis ovarian follicular epithelium soma encoded GO:0008071 1 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.018
heterochromatin organization GO:0070828 25 0.018
histone methylation GO:0016571 40 0.018
morphogenesis of an epithelium GO:0002009 276 0.018
Fly
protein dna complex subunit organization GO:0071824 86 0.018
cellular catabolic process GO:0044248 372 0.018
dorsal closure leading edge cell differentiation GO:0046663 2 0.018
protein localization GO:0008104 284 0.018
Fly
organonitrogen compound metabolic process GO:1901564 318 0.018
gene silencing by rna GO:0031047 57 0.017
gland morphogenesis GO:0022612 145 0.017
Fly
endocytosis GO:0006897 310 0.017
regulation of programmed cell death GO:0043067 152 0.017
regulation of histone modification GO:0031056 20 0.017
catabolic process GO:0009056 409 0.017
ovarian follicle cell development GO:0030707 248 0.017
Fly
regulation of protein acetylation GO:1901983 7 0.016
larval development GO:0002164 104 0.016
rna splicing via transesterification reactions GO:0000375 73 0.016
neuron fate commitment GO:0048663 50 0.015
Fly
positive regulation of histone acetylation GO:0035066 3 0.015
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 2 0.015
brain development GO:0007420 120 0.015
Fly
regulation of protein metabolic process GO:0051246 256 0.015
cytokinesis GO:0000910 90 0.015
negative regulation of cell division GO:0051782 17 0.015
stem cell maintenance GO:0019827 67 0.015
salivary gland histolysis GO:0035070 88 0.015
dna methylation or demethylation GO:0044728 4 0.015
gliogenesis GO:0042063 80 0.014
negative regulation of neuron differentiation GO:0045665 16 0.014
wing disc morphogenesis GO:0007472 344 0.014
Fly
regulation of microtubule cytoskeleton organization GO:0070507 41 0.014
negative regulation of signaling GO:0023057 219 0.014
organic acid metabolic process GO:0006082 103 0.014
negative regulation of nucleoside metabolic process GO:0045978 1 0.014
dorsal vessel heart proper cell fate commitment GO:0035053 2 0.014
eye development GO:0001654 323 0.014
Fly
histone h4 k12 acetylation GO:0043983 2 0.013
negative regulation of terminal cell fate specification open tracheal system GO:0035155 2 0.013
positive regulation of organelle organization GO:0010638 65 0.013
regulation of cytoskeleton organization GO:0051493 89 0.013
multi organism behavior GO:0051705 175 0.013
Fly
rna interference GO:0016246 27 0.013
regulation of cell proliferation involved in compound eye morphogenesis GO:2000495 2 0.012
regulation of mrna processing GO:0050684 71 0.012
oxoacid metabolic process GO:0043436 103 0.012
regulation of cell differentiation GO:0045595 302 0.012
Fly
regulation of cellular protein catabolic process GO:1903362 44 0.012
formation of a compartment boundary GO:0060288 4 0.012
regulation of cell development GO:0060284 215 0.012
nucleobase containing compound transport GO:0015931 56 0.011
oocyte fate commitment GO:0048600 2 0.011
single organism biosynthetic process GO:0044711 206 0.011
eggshell formation GO:0030703 105 0.011
Fly
ribonucleoprotein complex disassembly GO:0032988 1 0.011
alternative mrna splicing via spliceosome GO:0000380 60 0.011
establishment or maintenance of polarity of larval imaginal disc epithelium GO:0016336 3 0.011
multi organism reproductive behavior GO:0044705 121 0.011
anterior posterior axis specification follicular epithelium GO:0030714 2 0.011
negative regulation of nucleotide metabolic process GO:0045980 4 0.011
cellular ketone metabolic process GO:0042180 24 0.011
development of primary sexual characteristics GO:0045137 50 0.011
Fly
meiotic nuclear envelope disassembly GO:0051078 2 0.011
cellular component assembly involved in morphogenesis GO:0010927 151 0.011
Fly
enzyme linked receptor protein signaling pathway GO:0007167 179 0.010
border follicle cell delamination GO:0030709 3 0.010
stem cell differentiation GO:0048863 117 0.010
phospholipid transport GO:0015914 2 0.010
oocyte maturation GO:0001556 3 0.010
meiotic spindle checkpoint GO:0044779 1 0.010
regulation of apoptotic process GO:0042981 130 0.010
positive regulation of growth GO:0045927 75 0.010
cell cycle arrest GO:0007050 4 0.010

mod(mdg4) disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
artery disease DOID:0050828 0 0.018
aortic aneurysm DOID:3627 0 0.018
disease of anatomical entity DOID:7 0 0.018
vascular disease DOID:178 0 0.018
cardiovascular system disease DOID:1287 0 0.018
aortic disease DOID:520 0 0.018
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
head and neck cancer DOID:11934 0 0.013