Drosophila melanogaster

262 known processes

l(2)gl (Dmel_CG2671)

lethal (2) giant larvae

(Aliases: p127,l[[2]]gl,p127l(2)gl,lgl,Lgl,LGL,l(2),CG2671,L(2)gl,Dmel\CG2671,D-LGL,L(2)GL,l(2) giant larva,gl,l-gl,dlgl,MENE (2L)-B,l(2)giant larvae)

l(2)gl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
localization of cell GO:0051674 257 0.999
Zebrafish
cell migration GO:0016477 238 0.998
Zebrafish
digestive system development GO:0055123 149 0.996
malpighian tubule development GO:0072002 64 0.993
tube development GO:0035295 244 0.990
axonogenesis GO:0007409 290 0.989
Rat
female germ line cyst formation GO:0048135 42 0.989
regulation of anatomical structure morphogenesis GO:0022603 242 0.987
Zebrafish
regulation of growth GO:0040008 233 0.987
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.986
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 179 0.983
ovarian follicle cell migration GO:0007297 121 0.981
tissue morphogenesis GO:0048729 297 0.977
digestive tract morphogenesis GO:0048546 127 0.974
regulation of multicellular organismal development GO:2000026 414 0.973
malpighian tubule morphogenesis GO:0007443 44 0.967
developmental growth GO:0048589 280 0.967
axon guidance GO:0007411 233 0.964
ameboidal type cell migration GO:0001667 151 0.961
renal tubule development GO:0061326 64 0.956
growth GO:0040007 359 0.953
epithelial cell development GO:0002064 274 0.952
border follicle cell migration GO:0007298 113 0.950
cell motility GO:0048870 251 0.950
Zebrafish
urogenital system development GO:0001655 72 0.948
protein transport GO:0015031 155 0.927
epithelial cell migration GO:0010631 148 0.920
embryonic morphogenesis GO:0048598 206 0.914
single organism cellular localization GO:1902580 180 0.909
single organism nuclear import GO:1902593 51 0.904
stem cell fate commitment GO:0048865 25 0.903
tube morphogenesis GO:0035239 191 0.902
neurological system process GO:0050877 358 0.896
Fly
ovarian follicle cell development GO:0030707 248 0.894
protein targeting GO:0006605 64 0.891
single organism behavior GO:0044708 391 0.889
Fly
meiotic nuclear division GO:0007126 151 0.879
dna metabolic process GO:0006259 227 0.872
regulation of developmental growth GO:0048638 174 0.870
cell division GO:0051301 248 0.867
establishment or maintenance of cell polarity GO:0007163 167 0.867
immune system process GO:0002376 347 0.866
renal tubule morphogenesis GO:0061333 44 0.863
epithelium migration GO:0090132 148 0.858
neuron projection guidance GO:0097485 241 0.855
epithelial cell differentiation GO:0030855 322 0.852
germarium derived female germ line cyst formation GO:0030727 42 0.850
asymmetric cell division GO:0008356 37 0.841
organic substance transport GO:0071702 257 0.839
protein import into nucleus GO:0006606 51 0.834
germarium derived egg chamber formation GO:0007293 101 0.831
intracellular transport GO:0046907 228 0.828
Rat
regulation of cell morphogenesis GO:0022604 163 0.826
Zebrafish
dendrite morphogenesis GO:0048813 199 0.824
regulation of cell projection organization GO:0031344 92 0.824
single organism intracellular transport GO:1902582 207 0.823
Rat
regulation of protein transport GO:0051223 57 0.811
intracellular protein transport GO:0006886 104 0.794
hindgut development GO:0061525 58 0.793
embryonic development via the syncytial blastoderm GO:0001700 148 0.780
mushroom body development GO:0016319 70 0.773
regulation of cell proliferation GO:0042127 163 0.765
establishment of protein localization GO:0045184 163 0.764
meiotic cell cycle process GO:1903046 132 0.764
regulation of neurogenesis GO:0050767 158 0.763
regulation of dendrite morphogenesis GO:0048814 28 0.752
segmentation GO:0035282 207 0.749
cellular protein localization GO:0034613 160 0.743
regulation of cell shape GO:0008360 113 0.740
wnt signaling pathway GO:0016055 98 0.734
digestive tract development GO:0048565 149 0.727
dorsal appendage formation GO:0046843 47 0.710
negative regulation of signal transduction GO:0009968 206 0.709
regulation of cell differentiation GO:0045595 302 0.704
regulation of notch signaling pathway GO:0008593 100 0.700
stem cell division GO:0017145 69 0.698
spermatogenesis GO:0007283 200 0.697
chemotaxis GO:0006935 249 0.695
stem cell proliferation GO:0072089 88 0.694
chorion containing eggshell formation GO:0007304 105 0.690
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.679
Mouse
hindgut morphogenesis GO:0007442 58 0.676
regulation of vesicle mediated transport GO:0060627 59 0.672
cytokinesis GO:0000910 90 0.671
endomembrane system organization GO:0010256 119 0.668
protein localization to nucleus GO:0034504 55 0.658
membrane organization GO:0061024 112 0.658
dendrite development GO:0016358 204 0.654
tissue migration GO:0090130 155 0.653
establishment of epithelial cell polarity GO:0090162 13 0.640
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.639
Zebrafish
response to wounding GO:0009611 94 0.632
cellular macromolecule localization GO:0070727 220 0.617
adherens junction organization GO:0034332 27 0.608
germ cell migration GO:0008354 43 0.607
protein localization GO:0008104 284 0.607
actin filament based process GO:0030029 220 0.589
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.588
oocyte development GO:0048599 124 0.580
chemosensory behavior GO:0007635 106 0.569
establishment of protein localization to organelle GO:0072594 62 0.560
establishment of localization in cell GO:0051649 402 0.559
Rat
negative regulation of developmental process GO:0051093 201 0.556
oocyte axis specification GO:0007309 108 0.554
endocytosis GO:0006897 310 0.548
actin cytoskeleton organization GO:0030036 206 0.545
peripheral nervous system development GO:0007422 52 0.543
single organism cell adhesion GO:0098602 47 0.542
body morphogenesis GO:0010171 2 0.538
protein localization to organelle GO:0033365 82 0.527
programmed cell death GO:0012501 257 0.523
homeostatic process GO:0042592 199 0.521
regulation of protein localization GO:0032880 76 0.517
cell projection assembly GO:0030031 94 0.514
Zebrafish
heart field specification GO:0003128 0 0.514
single organismal cell cell adhesion GO:0016337 45 0.513
protein targeting to nucleus GO:0044744 51 0.513
columnar cuboidal epithelial cell development GO:0002066 249 0.510
negative regulation of apoptotic process GO:0043066 63 0.508
neural precursor cell proliferation GO:0061351 75 0.505
autophagy GO:0006914 108 0.504
regulation of apoptotic process GO:0042981 130 0.503
regulation of intracellular protein transport GO:0033157 46 0.502
spermatid development GO:0007286 98 0.498
negative regulation of cell cycle GO:0045786 116 0.490
regulation of epithelial cell proliferation GO:0050678 4 0.488
Zebrafish
apoptotic process GO:0006915 159 0.481
regulation of neuron differentiation GO:0045664 103 0.480
death GO:0016265 284 0.474
immune system development GO:0002520 57 0.454
mitotic spindle organization GO:0007052 220 0.453
single organism membrane organization GO:0044802 93 0.452
cell proliferation GO:0008283 299 0.449
positive regulation of cell differentiation GO:0045597 64 0.448
spindle organization GO:0007051 253 0.435
gastrulation GO:0007369 70 0.429
cytoplasmic transport GO:0016482 130 0.419
Rat
asymmetric protein localization involved in cell fate determination GO:0045167 9 0.416
germ line cyst formation GO:0048134 44 0.412
chorion containing eggshell pattern formation GO:0030381 11 0.412
axon development GO:0061564 297 0.410
Rat
head development GO:0060322 135 0.402
germarium derived oocyte fate determination GO:0007294 26 0.402
synapse assembly GO:0007416 143 0.402
sex differentiation GO:0007548 81 0.401
regulation of protein import into nucleus GO:0042306 28 0.397
negative regulation of epithelial cell proliferation GO:0050680 4 0.395
Zebrafish
renal system development GO:0072001 72 0.389
negative regulation of signaling GO:0023057 219 0.386
regulation of intracellular transport GO:0032386 64 0.379
regulation of axonogenesis GO:0050770 32 0.375
regulation of nervous system development GO:0051960 248 0.370
ovarian follicle cell stalk formation GO:0030713 17 0.369
positive regulation of growth GO:0045927 75 0.367
zonula adherens assembly GO:0045186 6 0.361
mitotic cytokinesis GO:0000281 50 0.359
eggshell formation GO:0030703 105 0.356
protein phosphorylation GO:0006468 169 0.353
positive regulation of cell size GO:0045793 21 0.353
regulation of cellular component size GO:0032535 98 0.344
regulation of nucleocytoplasmic transport GO:0046822 35 0.344
olfactory behavior GO:0042048 97 0.344
dorsal closure GO:0007391 79 0.341
negative regulation of cell cell adhesion GO:0022408 8 0.338
sensory organ precursor cell division GO:0045035 10 0.333
delamination GO:0060232 8 0.329
neuroblast proliferation GO:0007405 74 0.327
reproductive structure development GO:0048608 74 0.322
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.322
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.319
dna replication GO:0006260 48 0.315
meiotic cell cycle GO:0051321 171 0.313
morphogenesis of follicular epithelium GO:0016333 36 0.312
cellular response to radiation GO:0071478 52 0.311
negative regulation of programmed cell death GO:0043069 72 0.308
development of primary sexual characteristics GO:0045137 50 0.306
embryonic hindgut morphogenesis GO:0048619 48 0.302
regulation of neuron projection development GO:0010975 69 0.301
central nervous system development GO:0007417 201 0.300
asymmetric protein localization GO:0008105 33 0.296
regulation of programmed cell death GO:0043067 152 0.295
morphogenesis of an epithelium GO:0002009 276 0.291
oocyte microtubule cytoskeleton organization GO:0016325 35 0.287
regulation of cellular localization GO:0060341 136 0.283
regulation of cytoplasmic transport GO:1903649 47 0.272
neuroblast fate commitment GO:0014017 19 0.269
positive regulation of protein localization to nucleus GO:1900182 21 0.266
male gamete generation GO:0048232 201 0.263
organelle fission GO:0048285 340 0.256
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.254
mesoderm development GO:0007498 78 0.254
cell fate determination GO:0001709 91 0.254
i kappab kinase nf kappab signaling GO:0007249 6 0.253
negative regulation of cellular component organization GO:0051129 108 0.247
Zebrafish
taxis GO:0042330 304 0.247
negative regulation of cell proliferation GO:0008285 69 0.246
regionalization GO:0003002 416 0.242
regulation of dendrite development GO:0050773 37 0.241
axis specification GO:0009798 167 0.240
protein modification process GO:0036211 438 0.232
somatic stem cell maintenance GO:0035019 14 0.230
organelle localization GO:0051640 148 0.230
epithelial cell proliferation GO:0050673 15 0.229
Zebrafish
stem cell differentiation GO:0048863 117 0.224
Zebrafish
synaptic growth at neuromuscular junction GO:0051124 119 0.224
regulation of cell development GO:0060284 215 0.223
establishment of protein localization to plasma membrane GO:0090002 9 0.222
protein import GO:0017038 55 0.221
phosphorylation GO:0016310 294 0.220
positive regulation of stem cell differentiation GO:2000738 3 0.220
response to radiation GO:0009314 155 0.218
hindbrain development GO:0030902 2 0.213
nucleus localization GO:0051647 34 0.207
germarium derived female germ line cyst encapsulation GO:0030708 8 0.204
cuticle development GO:0042335 86 0.204
actin filament organization GO:0007015 126 0.203
transmembrane transport GO:0055085 139 0.203
regulation of epithelial cell differentiation GO:0030856 4 0.203
cell recognition GO:0008037 102 0.191
eggshell chorion assembly GO:0007306 66 0.191
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.187
epithelial tube morphogenesis GO:0060562 88 0.187
biological adhesion GO:0022610 138 0.183
regulation of anatomical structure size GO:0090066 163 0.182
cell competition in a multicellular organism GO:0035212 10 0.182
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.181
cellular ketone metabolic process GO:0042180 24 0.181
response to starvation GO:0042594 97 0.181
negative regulation of molecular function GO:0044092 51 0.174
melanotic encapsulation of foreign target GO:0035011 30 0.173
determination of adult lifespan GO:0008340 137 0.173
embryonic organ development GO:0048568 50 0.173
dorsal closure spreading of leading edge cells GO:0007395 4 0.172
cytoskeleton dependent cytokinesis GO:0061640 81 0.171
humoral immune response GO:0006959 117 0.170
negative regulation of cellular metabolic process GO:0031324 382 0.169
r3 r4 cell differentiation GO:0048056 12 0.168
regulation of catabolic process GO:0009894 170 0.167
Rat
multicellular organismal aging GO:0010259 140 0.167
regulation of establishment of protein localization GO:0070201 61 0.164
macromolecular complex assembly GO:0065003 256 0.161
Human
regulation of protein metabolic process GO:0051246 256 0.159
embryonic hemopoiesis GO:0035162 26 0.158
filopodium assembly GO:0046847 33 0.158
somatic stem cell division GO:0048103 37 0.157
imaginal disc derived leg morphogenesis GO:0007480 80 0.153
pericardium morphogenesis GO:0003344 2 0.153
cell junction assembly GO:0034329 42 0.150
Zebrafish
regulation of cell cell adhesion GO:0022407 21 0.149
hematopoietic or lymphoid organ development GO:0048534 57 0.147
larval development GO:0002164 104 0.146
endosomal transport GO:0016197 44 0.145
regulation of cell projection assembly GO:0060491 30 0.145
forebrain development GO:0030900 2 0.144
peptidyl amino acid modification GO:0018193 105 0.143
nucleocytoplasmic transport GO:0006913 72 0.142
regulation of transport GO:0051049 181 0.141
morphogenesis of embryonic epithelium GO:0016331 94 0.140
imaginal disc derived leg joint morphogenesis GO:0016348 15 0.140
regulation of protein localization to nucleus GO:1900180 29 0.138
reproductive system development GO:0061458 74 0.138
epithelial cell cell adhesion GO:0090136 6 0.138
cellular response to abiotic stimulus GO:0071214 58 0.136
nuclear import GO:0051170 51 0.135
nuclear division GO:0000280 332 0.134
morphogenesis of a polarized epithelium GO:0001738 93 0.134
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.133
cellular response to chemical stimulus GO:0070887 199 0.132
neuron death GO:0070997 27 0.132
cellular response to nutrient levels GO:0031669 62 0.131
neuron recognition GO:0008038 101 0.131
regulation of molecular function GO:0065009 217 0.131
i kappab phosphorylation GO:0007252 3 0.128
neuroblast fate determination GO:0007400 12 0.128
negative regulation of nervous system development GO:0051961 92 0.128
positive regulation of developmental process GO:0051094 143 0.125
adherens junction assembly GO:0034333 11 0.125
establishment of nucleus localization GO:0040023 26 0.122
regulation of transferase activity GO:0051338 58 0.122
regulation of intracellular signal transduction GO:1902531 236 0.122
Rat
photoreceptor cell development GO:0042461 96 0.121
male sex differentiation GO:0046661 25 0.120
vesicle mediated transport GO:0016192 381 0.119
Rat
centrosome cycle GO:0007098 137 0.115
oocyte construction GO:0007308 112 0.114
eye development GO:0001654 323 0.113
positive regulation of rna metabolic process GO:0051254 271 0.113
establishment of planar polarity GO:0001736 87 0.112
negative regulation of cell differentiation GO:0045596 143 0.110
positive regulation of developmental growth GO:0048639 62 0.110
reproductive behavior GO:0019098 122 0.110
negative regulation of cell death GO:0060548 81 0.108
stem cell maintenance GO:0019827 67 0.108
polarity specification of anterior posterior axis GO:0009949 5 0.107
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.107
regulation of tube diameter GO:0035296 14 0.105
multicellular organism growth GO:0035264 46 0.105
cellular protein modification process GO:0006464 438 0.104
cardiac muscle tissue development GO:0048738 9 0.102
spermatid differentiation GO:0048515 114 0.102
stem cell development GO:0048864 79 0.101
Zebrafish
branching morphogenesis of an epithelial tube GO:0048754 45 0.100
maintenance of location GO:0051235 73 0.099
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 1 0.098
pericardium development GO:0060039 2 0.097
extracellular structure organization GO:0043062 46 0.095
negative regulation of cell adhesion GO:0007162 9 0.095
protein complex biogenesis GO:0070271 201 0.095
Human
regulation of protein modification process GO:0031399 112 0.094
regulation of cytoskeleton organization GO:0051493 89 0.094
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.094
regulation of protein targeting GO:1903533 29 0.093
organ growth GO:0035265 56 0.092
nephron tubule morphogenesis GO:0072078 3 0.092
catabolic process GO:0009056 409 0.092
Rat
cell death GO:0008219 279 0.091
regulation of phosphorylation GO:0042325 147 0.091
larval lymph gland hemopoiesis GO:0035167 17 0.090
organelle assembly GO:0070925 198 0.090
Zebrafish
asymmetric neuroblast division GO:0055059 33 0.090
genitalia morphogenesis GO:0035112 16 0.089
plasma membrane organization GO:0007009 26 0.089
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.089
malpighian tubule tip cell differentiation GO:0061382 9 0.088
positive regulation of response to stimulus GO:0048584 323 0.088
cellular amino acid metabolic process GO:0006520 61 0.087
embryo development ending in birth or egg hatching GO:0009792 152 0.086
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.086
compound eye photoreceptor cell differentiation GO:0001751 140 0.086
cell growth GO:0016049 108 0.086
response to organic substance GO:0010033 284 0.085
regulation of malpighian tubule diameter GO:0035297 3 0.085
negative regulation of gtpase activity GO:0034260 1 0.084
cell cell junction organization GO:0045216 55 0.083
protein localization to plasma membrane GO:0072659 13 0.082
regulation of phosphate metabolic process GO:0019220 210 0.082
cell cycle dna replication GO:0044786 23 0.082
cellular response to starvation GO:0009267 61 0.081
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.081
gliogenesis GO:0042063 80 0.080
establishment of ommatidial planar polarity GO:0042067 49 0.079
transcription from rna polymerase ii promoter GO:0006366 368 0.079
regulation of actin cytoskeleton organization GO:0032956 42 0.079
chemical homeostasis GO:0048878 92 0.079
kidney development GO:0001822 3 0.078
cell rearrangement involved in malpighian tubule morphogenesis GO:0061334 3 0.078
positive regulation of transport GO:0051050 92 0.077
cellular component assembly involved in morphogenesis GO:0010927 151 0.076
Zebrafish
nephron development GO:0072006 3 0.075
cell fate specification GO:0001708 71 0.075
myotube cell development GO:0014904 3 0.075
positive regulation of intracellular protein transport GO:0090316 30 0.074
bmp signaling pathway involved in malpighian tubule cell chemotaxis GO:0061353 3 0.074
skin development GO:0043588 65 0.073
cell surface receptor signaling pathway involved in heart development GO:0061311 3 0.073
anterior posterior pattern specification GO:0009952 136 0.071
maintenance of cell polarity GO:0030011 18 0.071
Mouse
photoreceptor cell differentiation GO:0046530 170 0.071
negative regulation of mitotic cell cycle GO:0045930 109 0.071
dormancy process GO:0022611 2 0.070
nuclear transport GO:0051169 72 0.070
cellular macromolecular complex assembly GO:0034622 153 0.068
regulation of heart morphogenesis GO:2000826 3 0.068
regulation of synapse assembly GO:0051963 94 0.067
establishment of mitotic spindle localization GO:0040001 17 0.066
negative regulation of rna metabolic process GO:0051253 251 0.065
retinal cell programmed cell death GO:0046666 25 0.065
positive regulation of cell migration GO:0030335 2 0.065
ion transmembrane transport GO:0034220 122 0.065
negative regulation of notch signaling pathway GO:0045746 41 0.064
guanosine containing compound catabolic process GO:1901069 74 0.064
Rat
positive regulation of protein transport GO:0051222 37 0.063
cellular protein complex assembly GO:0043623 71 0.063
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.063
mitotic nuclear division GO:0007067 213 0.062
organic acid metabolic process GO:0006082 103 0.062
negative regulation of wnt signaling pathway GO:0030178 28 0.061
embryonic pattern specification GO:0009880 174 0.061
heart development GO:0007507 82 0.061
assembly of actomyosin apparatus involved in cytokinesis GO:0000912 11 0.061
regulation of immune system process GO:0002682 176 0.061
negative regulation of cell communication GO:0010648 223 0.061
small molecule metabolic process GO:0044281 305 0.059
Rat
positive regulation of phosphorus metabolic process GO:0010562 139 0.059
Rat
compound eye morphogenesis GO:0001745 249 0.059
positive regulation of neurogenesis GO:0050769 41 0.059
response to organic cyclic compound GO:0014070 89 0.058
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.057
oocyte morphogenesis GO:0048601 3 0.057
wound healing GO:0042060 75 0.056
actin cytoskeleton reorganization GO:0031532 22 0.056
muscle structure development GO:0061061 224 0.056
oxoacid metabolic process GO:0043436 103 0.056
cell cycle checkpoint GO:0000075 95 0.056
negative regulation of neural precursor cell proliferation GO:2000178 27 0.056
compound eye retinal cell programmed cell death GO:0046667 23 0.056
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.055
cell adhesion GO:0007155 136 0.055
positive regulation of signal transduction GO:0009967 223 0.054
hemopoiesis GO:0030097 46 0.054
response to extracellular stimulus GO:0009991 116 0.054
carbohydrate derivative catabolic process GO:1901136 118 0.053
Rat
regulation of ras protein signal transduction GO:0046578 93 0.053
Rat
eye morphogenesis GO:0048592 260 0.052
regulation of microtubule based process GO:0032886 49 0.052
cation homeostasis GO:0055080 51 0.051
striated muscle tissue development GO:0014706 27 0.051
female meiotic division GO:0007143 70 0.051
positive regulation of rna biosynthetic process GO:1902680 266 0.049
cell elongation involved in imaginal disc derived wing morphogenesis GO:0090254 5 0.048
protein polymerization GO:0051258 42 0.048
kidney epithelium development GO:0072073 3 0.048
regulation of cell size GO:0008361 63 0.048
cellular response to extracellular stimulus GO:0031668 64 0.048
motor neuron axon guidance GO:0008045 58 0.047
transforming growth factor beta receptor signaling pathway GO:0007179 16 0.047
neuroblast differentiation GO:0014016 29 0.046
ovarian nurse cell to oocyte transport GO:0007300 27 0.046
positive regulation of protein kinase activity GO:0045860 25 0.046
lipid metabolic process GO:0006629 121 0.046
purine nucleoside metabolic process GO:0042278 127 0.046
Rat
positive regulation of phosphorylation GO:0042327 87 0.046
establishment of organelle localization GO:0051656 122 0.045
cell maturation GO:0048469 144 0.045
mesenchymal cell differentiation GO:0048762 1 0.045
Zebrafish
regulation of filopodium assembly GO:0051489 24 0.045
developmental maturation GO:0021700 172 0.045
morphogenesis of a branching structure GO:0001763 45 0.044
negative regulation of epithelial cell migration GO:0010633 1 0.044
regulation of dna replication GO:0006275 13 0.044
regulation of epidermal cell differentiation GO:0045604 3 0.044
blastoderm segmentation GO:0007350 159 0.044
heterocycle catabolic process GO:0046700 166 0.044
Rat
regulation of cellular amino acid metabolic process GO:0006521 0 0.043
cell activation GO:0001775 9 0.043
skeletal muscle fiber development GO:0048741 3 0.042
positive regulation of mitotic cell cycle GO:0045931 34 0.042
cardiac cell fate commitment GO:0060911 17 0.042
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.041
brain development GO:0007420 120 0.041
cellular response to organic substance GO:0071310 132 0.041
nephron epithelium development GO:0072009 3 0.041
maintenance of protein location in cell GO:0032507 26 0.041
regulation of glial cell proliferation GO:0060251 11 0.041
imaginal disc derived wing hair organization GO:0035317 45 0.041
centrosome organization GO:0051297 163 0.040
regulation of protein phosphorylation GO:0001932 64 0.040
regulation of mitotic cell cycle GO:0007346 190 0.040
carboxylic acid metabolic process GO:0019752 92 0.040
regulation of mitosis GO:0007088 56 0.039
respiratory system development GO:0060541 213 0.039
nucleoside catabolic process GO:0009164 112 0.038
Rat
dorsal closure elongation of leading edge cells GO:0007394 10 0.038
positive regulation of multicellular organismal process GO:0051240 143 0.038
r3 r4 cell fate commitment GO:0007464 10 0.038
maternal determination of dorsal ventral axis ovarian follicular epithelium soma encoded GO:0008071 1 0.038
epithelial cell fate determination open tracheal system GO:0007425 2 0.038
appendage morphogenesis GO:0035107 397 0.038
positive regulation of signaling GO:0023056 243 0.038
oviposition GO:0018991 19 0.038
stress activated protein kinase signaling cascade GO:0031098 55 0.038
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 24 0.037
glial cell fate determination GO:0007403 3 0.037
zygotic specification of dorsal ventral axis GO:0007352 3 0.037
positive regulation of multicellular organism growth GO:0040018 21 0.037
maintenance of apical basal cell polarity GO:0035090 8 0.037
Mouse
canonical wnt signaling pathway GO:0060070 21 0.037
regulation of multicellular organism growth GO:0040014 40 0.037
meiotic dna repair synthesis GO:0000711 3 0.037
positive regulation of intracellular transport GO:0032388 42 0.036
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.036
dendrite regeneration GO:0031104 2 0.036
regulation of cell cycle process GO:0010564 181 0.036
leg disc morphogenesis GO:0007478 80 0.036
cell cycle g1 s phase transition GO:0044843 31 0.036
positive regulation of macromolecule metabolic process GO:0010604 405 0.036
regulation of endocytosis GO:0030100 37 0.036
regulation of cell cycle GO:0051726 291 0.036
organic substance catabolic process GO:1901575 308 0.035
Rat
defense response GO:0006952 300 0.035
negative regulation of cell development GO:0010721 62 0.035
regulation of cell proliferation involved in compound eye morphogenesis GO:2000495 2 0.035
multi organism behavior GO:0051705 175 0.035
phagocytosis GO:0006909 215 0.034
regulation of jnk cascade GO:0046328 40 0.034
regulation of organelle organization GO:0033043 196 0.034
hemocyte differentiation GO:0042386 38 0.034
cation transport GO:0006812 110 0.034
regulation of dna metabolic process GO:0051052 34 0.034
imaginal disc growth GO:0007446 37 0.034
defense response to bacterium GO:0042742 178 0.034
spinal cord development GO:0021510 1 0.034

l(2)gl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
brachydactyly DOID:0050581 0 0.077
bone development disease DOID:0080006 0 0.077
bone disease DOID:0080001 0 0.077
disease of anatomical entity DOID:7 0 0.077
dysostosis DOID:1934 0 0.077
musculoskeletal system disease DOID:17 0 0.077
connective tissue disease DOID:65 0 0.077