Drosophila melanogaster

59 known processes

pirk (Dmel_CG15678)

poor Imd response upon knock-in

(Aliases: Pirk,Pims,Dmel\CG15678,CG15678,BcDNA:SD16010,rudra,pims)

pirk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002816 3 0.859
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0006965 3 0.591
negative regulation of peptidoglycan recognition protein signaling pathway GO:0061060 3 0.531
antibacterial humoral response GO:0019731 44 0.443
pattern recognition receptor signaling pathway GO:0002221 2 0.425
defense response to other organism GO:0098542 225 0.402
activation of innate immune response GO:0002218 4 0.358
innate immune response activating signal transduction GO:0002758 2 0.348
biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002815 3 0.348
defense response to bacterium GO:0042742 178 0.343
response to external biotic stimulus GO:0043207 293 0.330
humoral immune response GO:0006959 117 0.321
immune response regulating signaling pathway GO:0002764 2 0.312
peptidoglycan metabolic process GO:0000270 3 0.309
antimicrobial humoral response GO:0019730 99 0.305
response to biotic stimulus GO:0009607 294 0.299
response to peptidoglycan GO:0032494 2 0.279
regulation of peptidoglycan recognition protein signaling pathway GO:0061058 4 0.275
defense response to gram positive bacterium GO:0050830 41 0.267
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0006964 12 0.262
cellular amide metabolic process GO:0043603 80 0.255
regulation of antibacterial peptide production GO:0002786 22 0.253
defense response to virus GO:0051607 23 0.243
immune system process GO:0002376 347 0.242
peptide metabolic process GO:0006518 80 0.239
regulation of defense response GO:0031347 102 0.233
regulation of response to biotic stimulus GO:0002831 63 0.232
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.228
regulation of cellular amide metabolic process GO:0034248 39 0.226
response to other organism GO:0051707 293 0.218
response to bacterium GO:0009617 198 0.216
defense response GO:0006952 300 0.215
production of molecular mediator of immune response GO:0002440 46 0.214
regulation of multi organism process GO:0043900 131 0.206
immune response GO:0006955 246 0.205
secondary metabolic process GO:0019748 75 0.200
antimicrobial peptide production GO:0002775 46 0.199
melanization defense response GO:0035006 45 0.195
defense response to gram negative bacterium GO:0050829 94 0.188
innate immune response GO:0045087 144 0.183
regulation of humoral immune response GO:0002920 51 0.182
antibacterial peptide biosynthetic process GO:0002780 22 0.181
peptidoglycan recognition protein signaling pathway GO:0061057 16 0.180
regulation of immune effector process GO:0002697 52 0.180
immune response activating signal transduction GO:0002757 2 0.176
response to lipopolysaccharide GO:0032496 4 0.166
peptidoglycan catabolic process GO:0009253 3 0.165
biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002812 14 0.165
positive regulation of antibacterial peptide production GO:0002803 20 0.164
positive regulation of response to biotic stimulus GO:0002833 31 0.158
negative regulation of cellular metabolic process GO:0031324 382 0.154
glycosaminoglycan catabolic process GO:0006027 3 0.151
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.146
regulation of antimicrobial humoral response GO:0002759 50 0.144
positive regulation of antimicrobial peptide production GO:0002225 28 0.138
cellular response to lipopolysaccharide GO:0071222 3 0.134
antibacterial peptide production GO:0002778 22 0.133
pigment metabolic process GO:0042440 84 0.131
negative regulation of signal transduction GO:0009968 206 0.131
melanin metabolic process GO:0006582 47 0.130
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.128
regulation of defense response to bacterium GO:1900424 30 0.127
regulation of production of molecular mediator of immune response GO:0002700 44 0.127
positive regulation of antimicrobial humoral response GO:0002760 28 0.121
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002813 14 0.118
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.115
positive regulation of biosynthetic process GO:0009891 316 0.109
positive regulation of defense response to bacterium GO:1900426 23 0.106
negative regulation of response to stimulus GO:0048585 258 0.104
positive regulation of cellular biosynthetic process GO:0031328 316 0.103
regulation of antimicrobial peptide production GO:0002784 44 0.101
negative regulation of defense response to bacterium GO:1900425 7 0.101
positive regulation of multi organism process GO:0043902 40 0.099
regulation of antibacterial peptide biosynthetic process GO:0002808 22 0.099
positive regulation of antibacterial peptide biosynthetic process GO:0006963 20 0.095
organonitrogen compound metabolic process GO:1901564 318 0.095
catabolic process GO:0009056 409 0.094
phenol containing compound metabolic process GO:0018958 57 0.093
antimicrobial peptide biosynthetic process GO:0002777 38 0.091
positive regulation of response to external stimulus GO:0032103 44 0.090
cellular response to molecule of bacterial origin GO:0071219 3 0.090
intracellular signal transduction GO:0035556 300 0.087
negative regulation of signaling GO:0023057 219 0.087
regulation of innate immune response GO:0045088 71 0.085
phosphorylation GO:0016310 294 0.084
regulation of response to stress GO:0080134 200 0.084
immune effector process GO:0002252 98 0.083
carbohydrate derivative metabolic process GO:1901135 217 0.083
regulation of immune system process GO:0002682 176 0.083
organic substance catabolic process GO:1901575 308 0.080
positive regulation of response to stimulus GO:0048584 323 0.080
organic hydroxy compound metabolic process GO:1901615 83 0.078
response to virus GO:0009615 28 0.076
negative regulation of response to external stimulus GO:0032102 22 0.073
response to nitrogen compound GO:1901698 90 0.071
regulation of immune response GO:0050776 118 0.071
regulation of response to external stimulus GO:0032101 115 0.070
cellular response to organic substance GO:0071310 132 0.070
regulation of intracellular signal transduction GO:1902531 236 0.070
positive regulation of defense response GO:0031349 59 0.068
positive regulation of immune response GO:0050778 63 0.064
negative regulation of defense response GO:0031348 35 0.064
amide biosynthetic process GO:0043604 42 0.062
defense response to fungus GO:0050832 48 0.061
response to organic substance GO:0010033 284 0.061
multicellular organismal aging GO:0010259 140 0.059
positive regulation of production of molecular mediator of immune response GO:0002702 28 0.059
mapk cascade GO:0000165 107 0.059
vesicle mediated transport GO:0016192 381 0.059
regulation of cellular response to stress GO:0080135 89 0.059
aging GO:0007568 143 0.058
positive regulation of cellular amide metabolic process GO:0034250 26 0.058
carbohydrate derivative catabolic process GO:1901136 118 0.058
peptide biosynthetic process GO:0043043 42 0.058
positive regulation of humoral immune response GO:0002922 28 0.058
regulation of mapk cascade GO:0043408 92 0.056
response to oxygen containing compound GO:1901700 200 0.056
cellular response to chemical stimulus GO:0070887 199 0.054
regulation of phosphate metabolic process GO:0019220 210 0.053
positive regulation of immune effector process GO:0002699 28 0.053
small molecule metabolic process GO:0044281 305 0.050
response to organonitrogen compound GO:0010243 75 0.050
organonitrogen compound catabolic process GO:1901565 128 0.050
cellular response to oxygen containing compound GO:1901701 79 0.049
macromolecule catabolic process GO:0009057 161 0.049
stress activated mapk cascade GO:0051403 52 0.049
negative regulation of immune system process GO:0002683 50 0.048
organonitrogen compound biosynthetic process GO:1901566 117 0.047
jnk cascade GO:0007254 50 0.046
regulation of phosphorylation GO:0042325 147 0.046
negative regulation of cell communication GO:0010648 223 0.045
glycosaminoglycan metabolic process GO:0030203 11 0.045
xenobiotic catabolic process GO:0042178 1 0.044
oxoacid metabolic process GO:0043436 103 0.044
signal transduction by phosphorylation GO:0023014 107 0.043
endocytosis GO:0006897 310 0.042
carboxylic acid metabolic process GO:0019752 92 0.042
negative regulation of stress activated protein kinase signaling cascade GO:0070303 20 0.041
cellular catabolic process GO:0044248 372 0.041
determination of adult lifespan GO:0008340 137 0.041
imaginal disc derived wing morphogenesis GO:0007476 337 0.040
positive regulation of immune system process GO:0002684 68 0.040
phagocytosis GO:0006909 215 0.040
regulation of phosphorus metabolic process GO:0051174 210 0.039
negative regulation of gene expression GO:0010629 387 0.039
antifungal humoral response GO:0019732 12 0.037
regionalization GO:0003002 416 0.036
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.036
regulation of jnk cascade GO:0046328 40 0.036
regulation of multicellular organismal development GO:2000026 414 0.035
lateral inhibition GO:0046331 206 0.035
response to organophosphorus GO:0046683 2 0.034
response to abiotic stimulus GO:0009628 341 0.034
protein modification process GO:0036211 438 0.034
fat soluble vitamin metabolic process GO:0006775 1 0.034
response to endogenous stimulus GO:0009719 119 0.033
post embryonic appendage morphogenesis GO:0035120 385 0.033
steroid catabolic process GO:0006706 1 0.033
cellular protein modification process GO:0006464 438 0.033
vitamin biosynthetic process GO:0009110 1 0.033
cell cell signaling involved in cell fate commitment GO:0045168 210 0.032
cellular response to biotic stimulus GO:0071216 4 0.032
response to nutrient levels GO:0031667 114 0.032
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.032
single organism biosynthetic process GO:0044711 206 0.031
single organism behavior GO:0044708 391 0.031
killing of cells of other organism GO:0031640 1 0.030
positive regulation of transcription dna templated GO:0045893 266 0.030
lipid metabolic process GO:0006629 121 0.030
fat soluble vitamin biosynthetic process GO:0042362 1 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.029
negative regulation of innate immune response GO:0045824 30 0.029
insecticide metabolic process GO:0017143 2 0.029
regulation of cell cycle GO:0051726 291 0.029
positive regulation of gene expression GO:0010628 290 0.028
imaginal disc derived appendage morphogenesis GO:0035114 395 0.028
positive regulation of signaling GO:0023056 243 0.028
positive regulation of cell communication GO:0010647 250 0.028
transcription from rna polymerase ii promoter GO:0006366 368 0.028
neurological system process GO:0050877 358 0.028
negative regulation of intracellular signal transduction GO:1902532 57 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.027
chemotaxis GO:0006935 249 0.027
positive regulation of macromolecule metabolic process GO:0010604 405 0.027
single organism catabolic process GO:0044712 228 0.027
regulation of stress activated mapk cascade GO:0032872 41 0.027
organic acid metabolic process GO:0006082 103 0.027
aminoglycan catabolic process GO:0006026 6 0.027
regulation of protein metabolic process GO:0051246 256 0.027
negative regulation of phosphorylation GO:0042326 35 0.027
negative regulation of immune response GO:0050777 39 0.027
body morphogenesis GO:0010171 2 0.027
negative regulation of developmental process GO:0051093 201 0.027
regulation of catalytic activity GO:0050790 185 0.026
negative regulation of rna metabolic process GO:0051253 251 0.026
cellular ketone metabolic process GO:0042180 24 0.026
regulation of cellular protein metabolic process GO:0032268 243 0.026
positive regulation of rna biosynthetic process GO:1902680 266 0.025
toxin catabolic process GO:0009407 1 0.025
organelle fission GO:0048285 340 0.025
appendage morphogenesis GO:0035107 397 0.025
negative regulation of phosphorus metabolic process GO:0010563 45 0.025
positive regulation of signal transduction GO:0009967 223 0.025
negative regulation of phosphate metabolic process GO:0045936 45 0.025
stress activated protein kinase signaling cascade GO:0031098 55 0.024
developmental growth GO:0048589 280 0.024
imaginal disc derived appendage development GO:0048737 399 0.024
axonogenesis GO:0007409 290 0.024
appendage development GO:0048736 401 0.024
regulation of melanization defense response GO:0035007 6 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.024
axon development GO:0061564 297 0.024
negative regulation of transcription dna templated GO:0045892 237 0.024
medium chain fatty acid metabolic process GO:0051791 1 0.024
protein localization GO:0008104 284 0.023
camera type eye development GO:0043010 4 0.023
negative regulation of multi organism process GO:0043901 29 0.023
growth GO:0040007 359 0.023
vitamin metabolic process GO:0006766 2 0.023
wing disc morphogenesis GO:0007472 344 0.023
synapse organization GO:0050808 196 0.022
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.022
neuron projection guidance GO:0097485 241 0.022
forebrain development GO:0030900 2 0.022
positive regulation of antifungal peptide biosynthetic process GO:0006967 5 0.022
response to lipid GO:0033993 38 0.022
toll signaling pathway GO:0008063 25 0.022
regulation of developmental growth GO:0048638 174 0.022
salivary gland development GO:0007431 162 0.022
negative regulation of rna biosynthetic process GO:1902679 240 0.022
regulation of cellular component biogenesis GO:0044087 201 0.022
sensory perception of chemical stimulus GO:0007606 116 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.022
positive regulation of nucleic acid templated transcription GO:1903508 266 0.022
eye development GO:0001654 323 0.022
response to molecule of bacterial origin GO:0002237 7 0.021
male gamete generation GO:0048232 201 0.021
cellular amino acid metabolic process GO:0006520 61 0.021
organic cyclic compound catabolic process GO:1901361 168 0.021
regulation of growth GO:0040008 233 0.021
positive regulation of rna metabolic process GO:0051254 271 0.021
spermatogenesis GO:0007283 200 0.021
lauric acid metabolic process GO:0048252 1 0.021
regulation of molecular function GO:0065009 217 0.021
epithelial cell development GO:0002064 274 0.021
developmental maturation GO:0021700 172 0.021
cellular component assembly involved in morphogenesis GO:0010927 151 0.021
multi organism behavior GO:0051705 175 0.020
response to starvation GO:0042594 97 0.020
negative regulation of multicellular organismal process GO:0051241 142 0.020
cell death GO:0008219 279 0.020
l glutamate import GO:0051938 1 0.020
respiratory system development GO:0060541 213 0.020
telencephalon development GO:0021537 2 0.020
heterocycle catabolic process GO:0046700 166 0.020
estrogen metabolic process GO:0008210 1 0.020
negative regulation of biosynthetic process GO:0009890 277 0.020
proteolysis GO:0006508 192 0.020
response to fungus GO:0009620 50 0.019
anion homeostasis GO:0055081 3 0.019
organophosphate metabolic process GO:0019637 195 0.019
melanotic encapsulation of foreign target GO:0035011 30 0.019
organic substance transport GO:0071702 257 0.019
organelle assembly GO:0070925 198 0.019
regulation of cellular amine metabolic process GO:0033238 3 0.019
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.019
regulation of catabolic process GO:0009894 170 0.019
anatomical structure homeostasis GO:0060249 97 0.019
homeostatic process GO:0042592 199 0.019
posttranscriptional regulation of gene expression GO:0010608 145 0.019
negative regulation of cellular biosynthetic process GO:0031327 277 0.019
regulation of transport GO:0051049 181 0.018
positive regulation of innate immune response GO:0045089 38 0.018
cellular lipid metabolic process GO:0044255 83 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.018
cellular nitrogen compound catabolic process GO:0044270 165 0.018
endomembrane system organization GO:0010256 119 0.018
regulation of cell differentiation GO:0045595 302 0.018
death GO:0016265 284 0.018
cell division GO:0051301 248 0.018
epithelial cell differentiation GO:0030855 322 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
embryonic pattern specification GO:0009880 174 0.018
purine containing compound metabolic process GO:0072521 155 0.018
negative regulation of mapk cascade GO:0043409 23 0.018
chromosome organization GO:0051276 360 0.017
establishment of localization in cell GO:0051649 402 0.017
connective tissue development GO:0061448 3 0.017
nucleoside triphosphate catabolic process GO:0009143 108 0.017
regulation of synapse structure and activity GO:0050803 128 0.017
sensory perception of smell GO:0007608 80 0.017
regulation of cellular catabolic process GO:0031329 157 0.017
digestive tract morphogenesis GO:0048546 127 0.017
single organism cellular localization GO:1902580 180 0.017
regulation of localization GO:0032879 275 0.017
retina development in camera type eye GO:0060041 4 0.017
negative regulation of nucleic acid templated transcription GO:1903507 240 0.017
nuclear division GO:0000280 332 0.017
gland morphogenesis GO:0022612 145 0.017
response to extracellular stimulus GO:0009991 116 0.017
positive regulation of phosphorus metabolic process GO:0010562 139 0.017
taxis GO:0042330 304 0.017
nucleobase containing small molecule metabolic process GO:0055086 174 0.017
regulation of autophagy GO:0010506 62 0.017
positive regulation of protein metabolic process GO:0051247 128 0.017
secondary metabolite catabolic process GO:0090487 1 0.017
spermatid differentiation GO:0048515 114 0.017
segmentation GO:0035282 207 0.017
regulation of gene expression epigenetic GO:0040029 128 0.017
actin filament based process GO:0030029 220 0.017
tube morphogenesis GO:0035239 191 0.017
cellular macromolecule localization GO:0070727 220 0.017
regulation of programmed cell death GO:0043067 152 0.016
response to copper ion GO:0046688 4 0.016
dorsal ventral pattern formation GO:0009953 133 0.016
regulation of synapse organization GO:0050807 110 0.016
aromatic compound catabolic process GO:0019439 166 0.016
developmental programmed cell death GO:0010623 138 0.016
regulation of anatomical structure size GO:0090066 163 0.016
compound eye morphogenesis GO:0001745 249 0.016
cellularization GO:0007349 90 0.016
blastoderm segmentation GO:0007350 159 0.016
polyol biosynthetic process GO:0046173 3 0.016
programmed cell death GO:0012501 257 0.016
regulation of toll signaling pathway GO:0008592 17 0.016
open tracheal system development GO:0007424 204 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
protein phosphorylation GO:0006468 169 0.016
response to hexose GO:0009746 3 0.016
positive regulation of phosphate metabolic process GO:0045937 139 0.016
negative regulation of protein metabolic process GO:0051248 85 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.016
purine ribonucleotide metabolic process GO:0009150 145 0.016
nucleotide metabolic process GO:0009117 161 0.015
cellular response to lipid GO:0071396 20 0.015
insecticide catabolic process GO:0046701 1 0.015
positive regulation of catabolic process GO:0009896 105 0.015
cell proliferation GO:0008283 299 0.015
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.015
tube development GO:0035295 244 0.015
columnar cuboidal epithelial cell development GO:0002066 249 0.015
macromolecular complex assembly GO:0065003 256 0.015
response to monosaccharide GO:0034284 4 0.015
exocrine system development GO:0035272 162 0.015
positive regulation of cell migration GO:0030335 2 0.015
cellular amine metabolic process GO:0044106 12 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
regulation of cell cycle process GO:0010564 181 0.015
limb development GO:0060173 1 0.015
establishment of protein localization GO:0045184 163 0.015
regulation of hydrolase activity GO:0051336 97 0.015
nucleobase containing compound catabolic process GO:0034655 165 0.015
regulation of organelle organization GO:0033043 196 0.015
positive regulation of molecular function GO:0044093 136 0.015
digestive tract development GO:0048565 149 0.015
negative regulation of cell cycle phase transition GO:1901988 103 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.015
small gtpase mediated signal transduction GO:0007264 88 0.015
protein transport GO:0015031 155 0.015
compound eye development GO:0048749 307 0.015
kidney development GO:0001822 3 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.015
positive regulation of cell death GO:0010942 69 0.015
positive regulation of cell motility GO:2000147 3 0.015
negative regulation of cell differentiation GO:0045596 143 0.015
ras protein signal transduction GO:0007265 88 0.015
protein processing GO:0016485 68 0.014
sensory organ morphogenesis GO:0090596 260 0.014
mitotic spindle organization GO:0007052 220 0.014
chromosome segregation GO:0007059 157 0.014
spermatid development GO:0007286 98 0.014
kidney morphogenesis GO:0060993 3 0.014
synapse assembly GO:0007416 143 0.014
positive regulation of melanization defense response GO:0035008 1 0.014
autophagy GO:0006914 108 0.014
ribonucleoside triphosphate catabolic process GO:0009203 108 0.014
regulation of apoptotic process GO:0042981 130 0.014
skeletal muscle fiber development GO:0048741 3 0.014
oxidation reduction process GO:0055114 123 0.014
response to temperature stimulus GO:0009266 106 0.014
response to organic cyclic compound GO:0014070 89 0.014
regulation of mitotic cell cycle GO:0007346 190 0.014
amine metabolic process GO:0009308 12 0.014
purine ribonucleoside metabolic process GO:0046128 127 0.014
ribonucleoside metabolic process GO:0009119 127 0.014
negative regulation of cell cycle GO:0045786 116 0.014
chromatin remodeling GO:0006338 72 0.014
nucleoside triphosphate metabolic process GO:0009141 120 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
organophosphate catabolic process GO:0046434 112 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
peptidyl amino acid modification GO:0018193 105 0.014
single organism intracellular transport GO:1902582 207 0.014
purine nucleoside metabolic process GO:0042278 127 0.014
l amino acid import GO:0043092 2 0.014
ribose phosphate metabolic process GO:0019693 145 0.014
nucleotide catabolic process GO:0009166 109 0.014
response to wounding GO:0009611 94 0.014
mitotic nuclear division GO:0007067 213 0.014
purine nucleoside triphosphate catabolic process GO:0009146 108 0.014
negative regulation of response to biotic stimulus GO:0002832 12 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
toxin metabolic process GO:0009404 2 0.014
ribonucleoside catabolic process GO:0042454 112 0.014
dendrite morphogenesis GO:0048813 199 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
mitotic dna integrity checkpoint GO:0044774 75 0.013
aminoglycan metabolic process GO:0006022 18 0.013
axis specification GO:0009798 167 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
nucleoside catabolic process GO:0009164 112 0.013
neuromuscular junction development GO:0007528 149 0.013
chaeta development GO:0022416 97 0.013
camera type eye morphogenesis GO:0048593 2 0.013
rna processing GO:0006396 147 0.013
adult behavior GO:0030534 137 0.013
cell cycle checkpoint GO:0000075 95 0.013
glycosyl compound catabolic process GO:1901658 112 0.013
actin filament organization GO:0007015 126 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
protein complex biogenesis GO:0070271 201 0.013
eye pigmentation GO:0048069 43 0.013
carbohydrate metabolic process GO:0005975 82 0.013
neutral lipid biosynthetic process GO:0046460 2 0.013
muscle structure development GO:0061061 224 0.013
dorsal ventral axis specification GO:0009950 66 0.013
positive regulation of cellular component organization GO:0051130 156 0.013
detection of stimulus involved in sensory perception GO:0050906 92 0.013
regulation of cell development GO:0060284 215 0.013
nucleoside metabolic process GO:0009116 127 0.013
response to glucose GO:0009749 2 0.013
tissue morphogenesis GO:0048729 297 0.013
regulation of epithelial cell proliferation GO:0050678 4 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
response to mercury ion GO:0046689 3 0.013
purine nucleotide catabolic process GO:0006195 109 0.013
positive regulation of autophagy GO:0010508 21 0.013
rhythmic process GO:0048511 106 0.013
purine nucleoside catabolic process GO:0006152 112 0.013
regulation of epithelial cell differentiation GO:0030856 4 0.013
response to alcohol GO:0097305 95 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.013
molting cycle chitin based cuticle GO:0007591 56 0.013
cuticle development GO:0042335 86 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
cell cycle phase transition GO:0044770 140 0.013
extrinsic apoptotic signaling pathway GO:0097191 1 0.013
digestive system development GO:0055123 149 0.013
chromatin organization GO:0006325 207 0.012
salivary gland morphogenesis GO:0007435 145 0.012
carbohydrate derivative biosynthetic process GO:1901137 85 0.012
synaptic transmission GO:0007268 288 0.012
cellular protein localization GO:0034613 160 0.012
ribonucleotide catabolic process GO:0009261 109 0.012
negative regulation of stress activated mapk cascade GO:0032873 19 0.012
regulation of small gtpase mediated signal transduction GO:0051056 93 0.012
mating GO:0007618 120 0.012
purine ribonucleoside catabolic process GO:0046130 112 0.012
protein maturation GO:0051604 71 0.012
positive regulation of cellular component biogenesis GO:0044089 80 0.012
hindbrain development GO:0030902 2 0.012
muscle organ development GO:0007517 127 0.012
imaginal disc pattern formation GO:0007447 91 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.012
membrane organization GO:0061024 112 0.012
negative regulation of cellular component organization GO:0051129 108 0.012
embryonic morphogenesis GO:0048598 206 0.012
regulation of cell death GO:0010941 173 0.012
gland development GO:0048732 191 0.012
tissue death GO:0016271 102 0.012
cholesterol homeostasis GO:0042632 3 0.012
chromatin modification GO:0016568 147 0.012
androgen metabolic process GO:0008209 1 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
organelle localization GO:0051640 148 0.012
guanosine containing compound metabolic process GO:1901068 74 0.012
eye morphogenesis GO:0048592 260 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.012
negative regulation of growth GO:0045926 84 0.012
dendrite development GO:0016358 204 0.012
dna metabolic process GO:0006259 227 0.012
positive regulation of hydrolase activity GO:0051345 78 0.012
meiotic chromosome segregation GO:0045132 59 0.012

pirk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.050
nervous system disease DOID:863 0 0.019
artery disease DOID:0050828 0 0.017
vascular disease DOID:178 0 0.017
cardiovascular system disease DOID:1287 0 0.017
hypertension DOID:10763 0 0.017
disease of metabolism DOID:0014667 0 0.016
inherited metabolic disorder DOID:655 0 0.016
essential hypertension DOID:10825 0 0.014
musculoskeletal system disease DOID:17 0 0.014
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013