Drosophila melanogaster

59 known processes

MED26 (Dmel_CG1793)

Mediator complex subunit 26

(Aliases: Arc70,ARC 70,CG1823,Med26,Dmel\CG1793,CG1793,dARC70)

MED26 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of biosynthetic process GO:0009890 277 0.792
eye morphogenesis GO:0048592 260 0.502
negative regulation of rna biosynthetic process GO:1902679 240 0.477
negative regulation of cellular biosynthetic process GO:0031327 277 0.465
negative regulation of rna metabolic process GO:0051253 251 0.454
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.411
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.354
negative regulation of transcription dna templated GO:0045892 237 0.336
dendrite development GO:0016358 204 0.310
regulation of mitotic cell cycle phase transition GO:1901990 130 0.302
single organism behavior GO:0044708 391 0.293
central nervous system development GO:0007417 201 0.290
negative regulation of cellular metabolic process GO:0031324 382 0.277
negative regulation of nucleic acid templated transcription GO:1903507 240 0.271
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.269
brain development GO:0007420 120 0.233
establishment of localization in cell GO:0051649 402 0.202
regulation of cell cycle phase transition GO:1901987 130 0.199
head development GO:0060322 135 0.197
regulation of cell cycle process GO:0010564 181 0.175
mrna metabolic process GO:0016071 124 0.167
microtubule organizing center organization GO:0031023 168 0.164
positive regulation of biosynthetic process GO:0009891 316 0.160
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.154
mitotic cell cycle phase transition GO:0044772 138 0.154
cell cycle phase transition GO:0044770 140 0.143
nuclear export GO:0051168 24 0.124
adult locomotory behavior GO:0008344 76 0.122
aggressive behavior GO:0002118 63 0.121
cell cycle checkpoint GO:0000075 95 0.121
eye development GO:0001654 323 0.120
compound eye morphogenesis GO:0001745 249 0.119
protein complex assembly GO:0006461 200 0.115
locomotory behavior GO:0007626 176 0.113
rhythmic behavior GO:0007622 76 0.100
rna localization GO:0006403 115 0.097
macromolecular complex assembly GO:0065003 256 0.096
organic substance transport GO:0071702 257 0.093
male gamete generation GO:0048232 201 0.093
embryonic development via the syncytial blastoderm GO:0001700 148 0.092
intracellular signal transduction GO:0035556 300 0.091
imaginal disc derived appendage morphogenesis GO:0035114 395 0.088
notch signaling pathway GO:0007219 120 0.086
neurological system process GO:0050877 358 0.086
sensory organ morphogenesis GO:0090596 260 0.083
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.083
nuclear division GO:0000280 332 0.082
protein complex biogenesis GO:0070271 201 0.082
neuron projection guidance GO:0097485 241 0.081
spindle organization GO:0007051 253 0.081
axonogenesis GO:0007409 290 0.080
cytoplasmic transport GO:0016482 130 0.080
regulation of cellular localization GO:0060341 136 0.078
centrosome organization GO:0051297 163 0.076
imaginal disc derived wing morphogenesis GO:0007476 337 0.076
protein localization GO:0008104 284 0.075
negative regulation of nervous system development GO:0051961 92 0.074
axon choice point recognition GO:0016198 26 0.072
regulation of gene expression epigenetic GO:0040029 128 0.070
negative regulation of gene expression GO:0010629 387 0.070
lateral inhibition GO:0046331 206 0.067
spermatogenesis GO:0007283 200 0.067
transcription from rna polymerase ii promoter GO:0006366 368 0.066
organelle fission GO:0048285 340 0.065
negative regulation of translation GO:0017148 28 0.062
response to biotic stimulus GO:0009607 294 0.062
cellular protein localization GO:0034613 160 0.062
body morphogenesis GO:0010171 2 0.060
negative regulation of cell cycle phase transition GO:1901988 103 0.060
protein modification process GO:0036211 438 0.060
organic acid metabolic process GO:0006082 103 0.059
regulation of developmental growth GO:0048638 174 0.059
negative regulation of cell cycle GO:0045786 116 0.058
forebrain development GO:0030900 2 0.057
regulation of response to stress GO:0080134 200 0.057
cell cycle g1 s phase transition GO:0044843 31 0.056
response to light stimulus GO:0009416 124 0.055
dna damage checkpoint GO:0000077 78 0.055
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.055
carboxylic acid metabolic process GO:0019752 92 0.052
meiotic cell cycle GO:0051321 171 0.051
regulation of intracellular signal transduction GO:1902531 236 0.051
circadian behavior GO:0048512 76 0.050
appendage development GO:0048736 401 0.050
cellular response to chemical stimulus GO:0070887 199 0.049
cellular response to dna damage stimulus GO:0006974 223 0.049
nuclear transport GO:0051169 72 0.047
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.047
regulation of cell cycle g1 s phase transition GO:1902806 23 0.047
growth GO:0040007 359 0.047
mitotic nuclear division GO:0007067 213 0.047
positive regulation of transcription dna templated GO:0045893 266 0.047
regulation of cytoplasmic transport GO:1903649 47 0.047
negative regulation of gene expression epigenetic GO:0045814 77 0.046
negative regulation of developmental growth GO:0048640 64 0.046
post embryonic appendage morphogenesis GO:0035120 385 0.045
anterior posterior pattern specification GO:0009952 136 0.045
wing disc morphogenesis GO:0007472 344 0.045
immune response GO:0006955 246 0.044
inter male aggressive behavior GO:0002121 60 0.044
dna integrity checkpoint GO:0031570 81 0.043
nucleobase containing compound transport GO:0015931 56 0.043
courtship behavior GO:0007619 68 0.042
mitotic dna damage checkpoint GO:0044773 74 0.040
cellular protein modification process GO:0006464 438 0.039
regulation of cell cycle GO:0051726 291 0.039
cell cell signaling involved in cell fate commitment GO:0045168 210 0.039
single organism intracellular transport GO:1902582 207 0.039
defense response GO:0006952 300 0.038
protein transport GO:0015031 155 0.037
regulation of cell shape GO:0008360 113 0.037
spermatid differentiation GO:0048515 114 0.036
chromatin assembly GO:0031497 48 0.036
regulation of localization GO:0032879 275 0.036
nucleocytoplasmic transport GO:0006913 72 0.036
mitotic dna integrity checkpoint GO:0044774 75 0.036
appendage morphogenesis GO:0035107 397 0.036
cell adhesion GO:0007155 136 0.035
oxoacid metabolic process GO:0043436 103 0.035
protein modification by small protein conjugation or removal GO:0070647 106 0.034
cell recognition GO:0008037 102 0.033
g1 s transition of mitotic cell cycle GO:0000082 31 0.033
response to other organism GO:0051707 293 0.033
multi organism behavior GO:0051705 175 0.033
cellular macromolecule localization GO:0070727 220 0.033
dendrite morphogenesis GO:0048813 199 0.033
adult behavior GO:0030534 137 0.032
chromatin silencing GO:0006342 76 0.032
regulation of growth GO:0040008 233 0.031
regulation of mitotic cell cycle GO:0007346 190 0.031
regulation of mrna processing GO:0050684 71 0.031
positive regulation of macromolecule metabolic process GO:0010604 405 0.031
translation GO:0006412 69 0.031
establishment or maintenance of cell polarity GO:0007163 167 0.030
centrosome cycle GO:0007098 137 0.030
locomotor rhythm GO:0045475 56 0.030
circadian rhythm GO:0007623 105 0.030
intracellular transport GO:0046907 228 0.030
muscle structure development GO:0061061 224 0.030
nucleotide catabolic process GO:0009166 109 0.029
organonitrogen compound metabolic process GO:1901564 318 0.029
regulation of neurogenesis GO:0050767 158 0.029
axon midline choice point recognition GO:0016199 26 0.029
small molecule metabolic process GO:0044281 305 0.029
intracellular protein transport GO:0006886 104 0.029
positive regulation of cellular biosynthetic process GO:0031328 316 0.028
regulation of transport GO:0051049 181 0.028
regulation of compound eye cone cell fate specification GO:0042682 4 0.028
chromosome organization GO:0051276 360 0.028
regulation of anatomical structure morphogenesis GO:0022603 242 0.027
mesoderm development GO:0007498 78 0.027
cellular catabolic process GO:0044248 372 0.027
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 13 0.026
establishment of spindle orientation GO:0051294 18 0.026
mitotic sister chromatid segregation GO:0000070 87 0.026
negative regulation of mitotic cell cycle GO:0045930 109 0.026
maintenance of location GO:0051235 73 0.025
regulation of protein localization GO:0032880 76 0.025
cell division GO:0051301 248 0.025
regulation of cellular component size GO:0032535 98 0.025
chromatin modification GO:0016568 147 0.024
morphogenesis of a branching structure GO:0001763 45 0.024
cell proliferation GO:0008283 299 0.023
posttranscriptional regulation of gene expression GO:0010608 145 0.023
chromosome segregation GO:0007059 157 0.023
axon development GO:0061564 297 0.022
morphogenesis of a branching epithelium GO:0061138 45 0.022
regulation of response to external stimulus GO:0032101 115 0.022
regulation of translation GO:0006417 56 0.022
feeding behavior GO:0007631 50 0.022
mitotic cell cycle checkpoint GO:0007093 88 0.021
regulation of anatomical structure size GO:0090066 163 0.021
hindbrain development GO:0030902 2 0.021
regulation of programmed cell death GO:0043067 152 0.021
chromatin organization GO:0006325 207 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.021
developmental growth GO:0048589 280 0.021
regulation of mrna metabolic process GO:1903311 72 0.021
multi multicellular organism process GO:0044706 123 0.020
melanotic encapsulation of foreign target GO:0035011 30 0.020
imaginal disc derived appendage development GO:0048737 399 0.020
compound eye development GO:0048749 307 0.020
positive regulation of molecular function GO:0044093 136 0.020
positive regulation of developmental process GO:0051094 143 0.019
histone deubiquitination GO:0016578 8 0.019
catabolic process GO:0009056 409 0.019
germarium derived female germ line cyst formation GO:0030727 42 0.019
mating behavior GO:0007617 106 0.019
carbohydrate derivative biosynthetic process GO:1901137 85 0.019
actin filament polymerization GO:0030041 27 0.019
regulation of protein transport GO:0051223 57 0.019
nucleobase containing compound catabolic process GO:0034655 165 0.019
regulation of cell development GO:0060284 215 0.019
eye photoreceptor cell differentiation GO:0001754 145 0.018
regulation of protein export from nucleus GO:0046825 3 0.018
regulation of protein catabolic process GO:0042176 55 0.018
nucleoside phosphate catabolic process GO:1901292 110 0.018
positive regulation of nucleic acid templated transcription GO:1903508 266 0.018
multicellular organismal reproductive behavior GO:0033057 110 0.018
response to organic cyclic compound GO:0014070 89 0.017
organic substance catabolic process GO:1901575 308 0.017
nitrogen compound transport GO:0071705 85 0.017
rhythmic process GO:0048511 106 0.017
response to oxygen containing compound GO:1901700 200 0.017
positive regulation of response to stimulus GO:0048584 323 0.017
regulation of intracellular transport GO:0032386 64 0.017
reproductive behavior GO:0019098 122 0.016
cell type specific apoptotic process GO:0097285 38 0.016
rna transport GO:0050658 46 0.016
axon guidance GO:0007411 233 0.016
immune system process GO:0002376 347 0.016
positive regulation of intracellular signal transduction GO:1902533 116 0.016
regulation of reproductive process GO:2000241 54 0.016
positive regulation of catabolic process GO:0009896 105 0.016
eggshell chorion assembly GO:0007306 66 0.016
spermatid development GO:0007286 98 0.016
regulation of molecular function GO:0065009 217 0.016
biological adhesion GO:0022610 138 0.016
programmed cell death GO:0012501 257 0.015
regulation of establishment of protein localization GO:0070201 61 0.015
mrna processing GO:0006397 104 0.015
brain morphogenesis GO:0048854 16 0.015
apical constriction involved in gastrulation GO:0003384 7 0.015
neuron projection regeneration GO:0031102 8 0.015
epithelial cell morphogenesis involved in gastrulation GO:0003381 7 0.015
pigment metabolic process GO:0042440 84 0.015
mitotic spindle organization GO:0007052 220 0.015
regulation of organelle organization GO:0033043 196 0.015
establishment of rna localization GO:0051236 47 0.014
organic cyclic compound catabolic process GO:1901361 168 0.014
cellular response to radiation GO:0071478 52 0.014
regionalization GO:0003002 416 0.014
response to nutrient levels GO:0031667 114 0.014
cellular response to light stimulus GO:0071482 37 0.014
actin filament based movement GO:0030048 26 0.014
tube development GO:0035295 244 0.014
muscle cell differentiation GO:0042692 103 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
oocyte development GO:0048599 124 0.014
negative regulation of cell differentiation GO:0045596 143 0.014
eye photoreceptor cell development GO:0042462 81 0.014
branching morphogenesis of an epithelial tube GO:0048754 45 0.014
negative regulation of phosphatase activity GO:0010923 3 0.013
response to wounding GO:0009611 94 0.013
regulation of hemocyte proliferation GO:0035206 37 0.013
ribonucleoside metabolic process GO:0009119 127 0.013
negative regulation of multicellular organismal process GO:0051241 142 0.013
neuron recognition GO:0008038 101 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
establishment of tissue polarity GO:0007164 87 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
gene silencing GO:0016458 138 0.013
mitotic g2 dna damage checkpoint GO:0007095 69 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.013
single organism carbohydrate metabolic process GO:0044723 72 0.013
positive regulation of rna metabolic process GO:0051254 271 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.013
response to hypoxia GO:0001666 53 0.013
rna export from nucleus GO:0006405 12 0.013
regulation of nucleobase containing compound transport GO:0032239 4 0.013
meiotic cell cycle process GO:1903046 132 0.013
peptidyl amino acid modification GO:0018193 105 0.013
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.013
camera type eye development GO:0043010 4 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
epithelial tube morphogenesis GO:0060562 88 0.012
response to radiation GO:0009314 155 0.012
single organism biosynthetic process GO:0044711 206 0.012
cellular response to oxidative stress GO:0034599 28 0.012
response to decreased oxygen levels GO:0036293 58 0.012
photoreceptor cell development GO:0042461 96 0.012
cellular response to abiotic stimulus GO:0071214 58 0.012
dephosphorylation GO:0016311 51 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
multi organism reproductive behavior GO:0044705 121 0.012
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.012
death GO:0016265 284 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.012
male mating behavior GO:0060179 70 0.011
cellular response to organic cyclic compound GO:0071407 32 0.011
telencephalon development GO:0021537 2 0.011
digestive system development GO:0055123 149 0.011
collateral sprouting GO:0048668 3 0.011
hematopoietic progenitor cell differentiation GO:0002244 1 0.011
photoreceptor cell differentiation GO:0046530 170 0.011
innate immune response GO:0045087 144 0.011
ras protein signal transduction GO:0007265 88 0.011
regulation of apoptotic process GO:0042981 130 0.011
positive regulation of signal transduction GO:0009967 223 0.011
deactivation of rhodopsin mediated signaling GO:0016059 17 0.011
organophosphate metabolic process GO:0019637 195 0.011
heterocycle catabolic process GO:0046700 166 0.011
centrosome duplication GO:0051298 121 0.011
covalent chromatin modification GO:0016569 106 0.011
rho protein signal transduction GO:0007266 14 0.011
response to nitrogen compound GO:1901698 90 0.011
positive regulation of organelle organization GO:0010638 65 0.011
regulation of multicellular organismal development GO:2000026 414 0.011
protein catabolic process GO:0030163 101 0.010
organonitrogen compound biosynthetic process GO:1901566 117 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.010
regulation of cytoskeleton organization GO:0051493 89 0.010
positive regulation of cell cycle GO:0045787 43 0.010
regulation of embryonic cell shape GO:0016476 30 0.010
compound eye photoreceptor cell differentiation GO:0001751 140 0.010
alternative mrna splicing via spliceosome GO:0000380 60 0.010
embryonic heart tube development GO:0035050 22 0.010
skin development GO:0043588 65 0.010
regulation of nucleocytoplasmic transport GO:0046822 35 0.010
taxis GO:0042330 304 0.010
dna conformation change GO:0071103 105 0.010
small gtpase mediated signal transduction GO:0007264 88 0.010

MED26 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.085
nervous system disease DOID:863 0 0.036
muscular disease DOID:0080000 0 0.023
musculoskeletal system disease DOID:17 0 0.023
sensory system disease DOID:0050155 0 0.011