Drosophila melanogaster

10 known processes

TwdlH (Dmel_CG31080)

TweedleH

(Aliases: Dmel\CG31080,CG31080,CG14241)

TwdlH biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
body morphogenesis GO:0010171 2 0.039
Fly
appendage development GO:0048736 401 0.039
catabolic process GO:0009056 409 0.038
cellular catabolic process GO:0044248 372 0.034
organonitrogen compound metabolic process GO:1901564 318 0.033
positive regulation of macromolecule metabolic process GO:0010604 405 0.033
imaginal disc derived appendage morphogenesis GO:0035114 395 0.033
appendage morphogenesis GO:0035107 397 0.033
imaginal disc derived appendage development GO:0048737 399 0.032
positive regulation of gene expression GO:0010628 290 0.032
wing disc morphogenesis GO:0007472 344 0.031
regionalization GO:0003002 416 0.031
vesicle mediated transport GO:0016192 381 0.030
protein modification process GO:0036211 438 0.029
post embryonic appendage morphogenesis GO:0035120 385 0.029
response to abiotic stimulus GO:0009628 341 0.028
endocytosis GO:0006897 310 0.028
small molecule metabolic process GO:0044281 305 0.028
imaginal disc derived wing morphogenesis GO:0007476 337 0.028
organic substance catabolic process GO:1901575 308 0.028
response to biotic stimulus GO:0009607 294 0.027
positive regulation of response to stimulus GO:0048584 323 0.027
cellular protein modification process GO:0006464 438 0.027
single organism catabolic process GO:0044712 228 0.027
positive regulation of cellular biosynthetic process GO:0031328 316 0.026
organic substance transport GO:0071702 257 0.026
sensory organ morphogenesis GO:0090596 260 0.026
positive regulation of biosynthetic process GO:0009891 316 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.025
response to organic substance GO:0010033 284 0.025
carboxylic acid metabolic process GO:0019752 92 0.025
regulation of multicellular organismal development GO:2000026 414 0.025
negative regulation of response to stimulus GO:0048585 258 0.025
response to other organism GO:0051707 293 0.025
intracellular signal transduction GO:0035556 300 0.025
neurological system process GO:0050877 358 0.025
eye morphogenesis GO:0048592 260 0.025
compound eye development GO:0048749 307 0.024
actin filament based process GO:0030029 220 0.024
negative regulation of gene expression GO:0010629 387 0.024
positive regulation of rna biosynthetic process GO:1902680 266 0.024
regulation of cellular ketone metabolic process GO:0010565 3 0.024
organic acid metabolic process GO:0006082 103 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.023
phagocytosis GO:0006909 215 0.023
establishment of localization in cell GO:0051649 402 0.023
protein localization GO:0008104 284 0.023
response to external biotic stimulus GO:0043207 293 0.023
oxoacid metabolic process GO:0043436 103 0.023
single organism behavior GO:0044708 391 0.022
homeostatic process GO:0042592 199 0.022
eye development GO:0001654 323 0.022
response to bacterium GO:0009617 198 0.022
positive regulation of signaling GO:0023056 243 0.022
regulation of cellular amine metabolic process GO:0033238 3 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.021
regulation of localization GO:0032879 275 0.021
cell proliferation GO:0008283 299 0.021
defense response GO:0006952 300 0.021
sensory perception of chemical stimulus GO:0007606 116 0.021
amine metabolic process GO:0009308 12 0.021
forebrain development GO:0030900 2 0.020
cellular ketone metabolic process GO:0042180 24 0.020
cellular amine metabolic process GO:0044106 12 0.020
cell death GO:0008219 279 0.020
compound eye morphogenesis GO:0001745 249 0.020
positive regulation of rna metabolic process GO:0051254 271 0.020
response to lipopolysaccharide GO:0032496 4 0.020
death GO:0016265 284 0.020
proteolysis GO:0006508 192 0.020
actin cytoskeleton organization GO:0030036 206 0.019
cellular amino acid metabolic process GO:0006520 61 0.019
regulation of intracellular signal transduction GO:1902531 236 0.019
negative regulation of signal transduction GO:0009968 206 0.019
negative regulation of cellular metabolic process GO:0031324 382 0.019
regulation of transport GO:0051049 181 0.019
phosphorylation GO:0016310 294 0.019
xenobiotic catabolic process GO:0042178 1 0.019
macromolecular complex assembly GO:0065003 256 0.019
response to oxygen containing compound GO:1901700 200 0.019
kidney development GO:0001822 3 0.019
regulation of cell cycle GO:0051726 291 0.018
immune system process GO:0002376 347 0.018
epithelial cell development GO:0002064 274 0.018
positive regulation of cell communication GO:0010647 250 0.018
positive regulation of signal transduction GO:0009967 223 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.018
camera type eye development GO:0043010 4 0.018
actin filament organization GO:0007015 126 0.018
positive regulation of nucleic acid templated transcription GO:1903508 266 0.018
cellular response to chemical stimulus GO:0070887 199 0.017
nuclear division GO:0000280 332 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
epithelial cell differentiation GO:0030855 322 0.017
regulation of protein metabolic process GO:0051246 256 0.017
carbohydrate derivative metabolic process GO:1901135 217 0.017
morphogenesis of an epithelium GO:0002009 276 0.017
programmed cell death GO:0012501 257 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
response to organophosphorus GO:0046683 2 0.017
organelle fission GO:0048285 340 0.017
single organism biosynthetic process GO:0044711 206 0.017
cellular macromolecule localization GO:0070727 220 0.017
positive regulation of transcription dna templated GO:0045893 266 0.017
growth GO:0040007 359 0.017
transcription from rna polymerase ii promoter GO:0006366 368 0.016
gland development GO:0048732 191 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
negative regulation of biosynthetic process GO:0009890 277 0.016
chromosome organization GO:0051276 360 0.016
anterior posterior pattern specification GO:0009952 136 0.016
organic cyclic compound catabolic process GO:1901361 168 0.016
negative regulation of signaling GO:0023057 219 0.016
cuticle development GO:0042335 86 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
anion homeostasis GO:0055081 3 0.016
regulation of catalytic activity GO:0050790 185 0.016
columnar cuboidal epithelial cell development GO:0002066 249 0.016
protein transport GO:0015031 155 0.016
steroid catabolic process GO:0006706 1 0.015
regulation of organelle organization GO:0033043 196 0.015
multi organism behavior GO:0051705 175 0.015
respiratory system development GO:0060541 213 0.015
gene silencing GO:0016458 138 0.015
immune response GO:0006955 246 0.015
defense response to other organism GO:0098542 225 0.015
regulation of molecular function GO:0065009 217 0.015
developmental growth GO:0048589 280 0.015
regulation of response to stress GO:0080134 200 0.015
protein phosphorylation GO:0006468 169 0.015
posttranscriptional regulation of gene expression GO:0010608 145 0.015
adult behavior GO:0030534 137 0.015
aromatic compound catabolic process GO:0019439 166 0.015
establishment of protein localization GO:0045184 163 0.015
cellular nitrogen compound catabolic process GO:0044270 165 0.015
heterocycle catabolic process GO:0046700 166 0.015
macromolecule catabolic process GO:0009057 161 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
negative regulation of cellular biosynthetic process GO:0031327 277 0.015
protein complex assembly GO:0006461 200 0.015
response to nutrient levels GO:0031667 114 0.014
tissue morphogenesis GO:0048729 297 0.014
open tracheal system development GO:0007424 204 0.014
developmental maturation GO:0021700 172 0.014
organophosphate metabolic process GO:0019637 195 0.014
sterol homeostasis GO:0055092 4 0.014
photoreceptor cell differentiation GO:0046530 170 0.014
taxis GO:0042330 304 0.014
spindle organization GO:0007051 253 0.014
regulation of anatomical structure morphogenesis GO:0022603 242 0.014
ion transport GO:0006811 145 0.014
polyol biosynthetic process GO:0046173 3 0.014
regulation of immune system process GO:0002682 176 0.014
telencephalon development GO:0021537 2 0.014
negative regulation of cell communication GO:0010648 223 0.014
cholesterol homeostasis GO:0042632 3 0.014
connective tissue development GO:0061448 3 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.014
cellular protein localization GO:0034613 160 0.014
intracellular transport GO:0046907 228 0.014
localization of cell GO:0051674 257 0.014
eye photoreceptor cell differentiation GO:0001754 145 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.014
cell cell signaling involved in cell fate commitment GO:0045168 210 0.014
dna metabolic process GO:0006259 227 0.014
regulation of cell proliferation GO:0042127 163 0.014
chromosome segregation GO:0007059 157 0.014
regulation of cell death GO:0010941 173 0.014
negative regulation of rna biosynthetic process GO:1902679 240 0.014
hormone catabolic process GO:0042447 3 0.014
chromatin organization GO:0006325 207 0.014
benzene containing compound metabolic process GO:0042537 3 0.013
exocrine system development GO:0035272 162 0.013
sensory perception GO:0007600 196 0.013
positive regulation of multicellular organismal process GO:0051240 143 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
enzyme linked receptor protein signaling pathway GO:0007167 179 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.013
response to nitrogen compound GO:1901698 90 0.013
mitotic nuclear division GO:0007067 213 0.013
positive regulation of cell migration GO:0030335 2 0.013
salivary gland development GO:0007431 162 0.013
response to endogenous stimulus GO:0009719 119 0.013
reproductive behavior GO:0019098 122 0.013
response to organic cyclic compound GO:0014070 89 0.013
response to extracellular stimulus GO:0009991 116 0.013
lateral inhibition GO:0046331 206 0.013
gland morphogenesis GO:0022612 145 0.013
lipid metabolic process GO:0006629 121 0.013
nucleoside phosphate metabolic process GO:0006753 162 0.013
endomembrane system organization GO:0010256 119 0.013
single organism intracellular transport GO:1902582 207 0.013
response to glucose GO:0009749 2 0.013
ovarian follicle cell development GO:0030707 248 0.013
cation transport GO:0006812 110 0.013
protein complex biogenesis GO:0070271 201 0.013
positive regulation of cell motility GO:2000147 3 0.013
response to hexose GO:0009746 3 0.013
ras protein signal transduction GO:0007265 88 0.013
innate immune response GO:0045087 144 0.013
response to radiation GO:0009314 155 0.012
response to alcohol GO:0097305 95 0.012
regulation of multi organism process GO:0043900 131 0.012
regulation of programmed cell death GO:0043067 152 0.012
regulation of gene expression epigenetic GO:0040029 128 0.012
tube development GO:0035295 244 0.012
detection of stimulus involved in sensory perception GO:0050906 92 0.012
salt aversion GO:0035199 3 0.012
response to monosaccharide GO:0034284 4 0.012
lauric acid metabolic process GO:0048252 1 0.012
salivary gland morphogenesis GO:0007435 145 0.012
chromatin modification GO:0016568 147 0.012
regulation of developmental growth GO:0048638 174 0.012
mitotic spindle organization GO:0007052 220 0.012
positive regulation of developmental process GO:0051094 143 0.012
negative regulation of rna metabolic process GO:0051253 251 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
nucleotide metabolic process GO:0009117 161 0.012
regulation of growth GO:0040008 233 0.012
ethanolamine containing compound metabolic process GO:0042439 4 0.012
spermatogenesis GO:0007283 200 0.012
multi multicellular organism process GO:0044706 123 0.012
vitamin metabolic process GO:0006766 2 0.012
regulation of lipid transport GO:0032368 3 0.012
cell adhesion GO:0007155 136 0.012
negative regulation of nucleic acid templated transcription GO:1903507 240 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
defense response to bacterium GO:0042742 178 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
regulation of cell differentiation GO:0045595 302 0.012
synaptic transmission GO:0007268 288 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
multicellular organismal reproductive behavior GO:0033057 110 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
transmembrane transport GO:0055085 139 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
segmentation GO:0035282 207 0.012
chitin based cuticle development GO:0040003 49 0.012
triglyceride biosynthetic process GO:0019432 2 0.012
cellular response to organic substance GO:0071310 132 0.012
regulation of cellular localization GO:0060341 136 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
locomotory behavior GO:0007626 176 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
apoptotic process GO:0006915 159 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
male gamete generation GO:0048232 201 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.012
positive regulation of cellular component organization GO:0051130 156 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.012
androgen metabolic process GO:0008209 1 0.012
defense response to gram negative bacterium GO:0050829 94 0.012
regulation of anatomical structure size GO:0090066 163 0.011
axis specification GO:0009798 167 0.011
purine containing compound metabolic process GO:0072521 155 0.011
response to copper ion GO:0046688 4 0.011
positive regulation of molecular function GO:0044093 136 0.011
regulation of cell cycle process GO:0010564 181 0.011
developmental programmed cell death GO:0010623 138 0.011
humoral immune response GO:0006959 117 0.011
dendrite morphogenesis GO:0048813 199 0.011
chemical homeostasis GO:0048878 92 0.011
positive regulation of catabolic process GO:0009896 105 0.011
photoreceptor cell development GO:0042461 96 0.011
monocarboxylic acid transport GO:0015718 3 0.011
cell division GO:0051301 248 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
cellular homeostasis GO:0019725 80 0.011
central nervous system development GO:0007417 201 0.011
single organism cellular localization GO:1902580 180 0.011
regulation of immune response GO:0050776 118 0.011
sensory perception of salty taste GO:0050914 3 0.011
response to organonitrogen compound GO:0010243 75 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
cellular lipid metabolic process GO:0044255 83 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.011
cellular response to ethanol GO:0071361 4 0.011
regulation of proteolysis GO:0030162 87 0.011
intracellular protein transport GO:0006886 104 0.011
biological adhesion GO:0022610 138 0.011
embryonic pattern specification GO:0009880 174 0.011
anatomical structure homeostasis GO:0060249 97 0.011
detection of chemical stimulus GO:0009593 93 0.011
immune response activating signal transduction GO:0002757 2 0.011
chemotaxis GO:0006935 249 0.011
secretion by cell GO:0032940 101 0.011
cell motility GO:0048870 251 0.011
mating GO:0007618 120 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
detection of stimulus GO:0051606 156 0.011
organelle assembly GO:0070925 198 0.011
dendrite development GO:0016358 204 0.010
wound healing GO:0042060 75 0.010
mesenchymal cell differentiation GO:0048762 1 0.010
response to starvation GO:0042594 97 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.010
fat soluble vitamin metabolic process GO:0006775 1 0.010
regulation of mitotic cell cycle phase transition GO:1901990 130 0.010
ribonucleotide metabolic process GO:0009259 145 0.010
tissue death GO:0016271 102 0.010
positive regulation of protein metabolic process GO:0051247 128 0.010
multi organism reproductive behavior GO:0044705 121 0.010
imaginal disc pattern formation GO:0007447 91 0.010
histolysis GO:0007559 102 0.010
toxin catabolic process GO:0009407 1 0.010
salivary gland histolysis GO:0035070 88 0.010
cholesterol transport GO:0030301 2 0.010
cellular protein catabolic process GO:0044257 83 0.010
regulation of response to external stimulus GO:0032101 115 0.010
negative regulation of developmental process GO:0051093 201 0.010
vitamin biosynthetic process GO:0009110 1 0.010
glycosyl compound metabolic process GO:1901657 127 0.010
mating behavior GO:0007617 106 0.010
negative regulation of transcription dna templated GO:0045892 237 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.010
camera type eye morphogenesis GO:0048593 2 0.010
limb development GO:0060173 1 0.010
neutral lipid biosynthetic process GO:0046460 2 0.010
secretion GO:0046903 109 0.010
signal transduction by phosphorylation GO:0023014 107 0.010
regulation of apoptotic process GO:0042981 130 0.010

TwdlH disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.039
disease of metabolism DOID:0014667 0 0.018
nervous system disease DOID:863 0 0.016
inherited metabolic disorder DOID:655 0 0.016
cardiovascular system disease DOID:1287 0 0.012
acquired metabolic disease DOID:0060158 0 0.011
musculoskeletal system disease DOID:17 0 0.011
diabetes mellitus DOID:9351 0 0.011
carbohydrate metabolism disease DOID:0050013 0 0.011
glucose metabolism disease DOID:4194 0 0.011
urinary system disease DOID:18 0 0.011
disease of cellular proliferation DOID:14566 0 0.010
sensory system disease DOID:0050155 0 0.010