|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
270 |
0.976
|
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
277 |
0.960
|
|
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
237 |
0.957
|
|
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
267 |
0.926
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
277 |
0.903
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
354 |
0.866
|
Yeast |
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
368 |
0.833
|
Yeast |
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
251 |
0.830
|
|
|
|
negative regulation of rna biosynthetic process
|
GO:1902679 |
240 |
0.767
|
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
261 |
0.710
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
378 |
0.704
|
Yeast |
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
265 |
0.670
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
204 |
0.638
|
Yeast |
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
266 |
0.623
|
Yeast |
|
|
negative regulation of gene expression
|
GO:0010629 |
387 |
0.599
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
271 |
0.572
|
Yeast |
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
240 |
0.558
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
316 |
0.552
|
Yeast |
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
332 |
0.502
|
Yeast |
|
|
regulation of gene silencing
|
GO:0060968 |
63 |
0.442
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
290 |
0.421
|
Yeast |
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
382 |
0.421
|
|
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
405 |
0.395
|
Yeast |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
119 |
0.387
|
|
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
266 |
0.386
|
Yeast |
|
|
nuclear division
|
GO:0000280 |
332 |
0.369
|
|
|
|
salivary gland development
|
GO:0007431 |
162 |
0.348
|
|
|
|
chromosome organization
|
GO:0051276 |
360 |
0.329
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
283 |
0.317
|
Yeast |
|
|
salivary gland morphogenesis
|
GO:0007435 |
145 |
0.314
|
|
|
|
gland development
|
GO:0048732 |
191 |
0.283
|
|
|
|
gene silencing
|
GO:0016458 |
138 |
0.280
|
|
|
|
sister chromatid segregation
|
GO:0000819 |
92 |
0.262
|
|
|
|
cell proliferation
|
GO:0008283 |
299 |
0.224
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
293 |
0.215
|
|
|
|
homeostatic process
|
GO:0042592 |
199 |
0.195
|
|
|
|
death
|
GO:0016265 |
284 |
0.189
|
|
|
|
circulatory system development
|
GO:0072359 |
82 |
0.186
|
|
|
|
cell death
|
GO:0008219 |
279 |
0.185
|
|
|
|
negative regulation of gene expression epigenetic
|
GO:0045814 |
77 |
0.182
|
|
|
|
imaginal disc derived appendage development
|
GO:0048737 |
399 |
0.178
|
|
|
|
taxis
|
GO:0042330 |
304 |
0.169
|
|
|
|
gland morphogenesis
|
GO:0022612 |
145 |
0.168
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
341 |
0.162
|
|
|
|
cell migration
|
GO:0016477 |
238 |
0.159
|
|
|
|
exocrine system development
|
GO:0035272 |
162 |
0.155
|
|
|
|
response to alcohol
|
GO:0097305 |
95 |
0.150
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
294 |
0.141
|
|
|
|
epithelium migration
|
GO:0090132 |
148 |
0.130
|
|
|
|
programmed cell death
|
GO:0012501 |
257 |
0.126
|
|
|
|
small molecule metabolic process
|
GO:0044281 |
305 |
0.125
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
316 |
0.125
|
Yeast |
|
|
cellular protein modification process
|
GO:0006464 |
438 |
0.120
|
|
|
|
histolysis
|
GO:0007559 |
102 |
0.116
|
|
|
|
tissue migration
|
GO:0090130 |
155 |
0.113
|
|
|
|
oxoacid metabolic process
|
GO:0043436 |
103 |
0.113
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
151 |
0.112
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
80 |
0.109
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
138 |
0.107
|
|
|
|
regulation of chromatin silencing
|
GO:0031935 |
36 |
0.107
|
|
|
|
imaginal disc derived appendage morphogenesis
|
GO:0035114 |
395 |
0.106
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
87 |
0.106
|
|
|
|
organelle fission
|
GO:0048285 |
340 |
0.106
|
|
|
|
chromatin modification
|
GO:0016568 |
147 |
0.103
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
266 |
0.096
|
Yeast |
|
|
muscle structure development
|
GO:0061061 |
224 |
0.093
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
163 |
0.085
|
|
|
|
salivary gland cell autophagic cell death
|
GO:0035071 |
83 |
0.084
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
0 |
0.080
|
|
|
|
stem cell differentiation
|
GO:0048863 |
117 |
0.079
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
213 |
0.079
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
128 |
0.074
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
92 |
0.074
|
|
|
|
chromatin silencing
|
GO:0006342 |
76 |
0.074
|
|
|
|
mitotic cell cycle embryonic
|
GO:0045448 |
38 |
0.069
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
243 |
0.069
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
156 |
0.069
|
|
|
|
regulation of molecular function
|
GO:0065009 |
217 |
0.067
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
138 |
0.067
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
206 |
0.065
|
|
|
|
wing disc morphogenesis
|
GO:0007472 |
344 |
0.063
|
|
|
|
camera type eye development
|
GO:0043010 |
4 |
0.061
|
Zebrafish |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
0 |
0.059
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
12 |
0.057
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
64 |
0.057
|
|
|
|
protein modification process
|
GO:0036211 |
438 |
0.057
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
276 |
0.056
|
|
|
|
organelle localization
|
GO:0051640 |
148 |
0.055
|
|
|
|
post embryonic appendage morphogenesis
|
GO:0035120 |
385 |
0.053
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
22 |
0.050
|
|
|
|
response to organic substance
|
GO:0010033 |
284 |
0.049
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
4 |
0.049
|
|
|
|
tissue death
|
GO:0016271 |
102 |
0.048
|
|
|
|
regulation of localization
|
GO:0032879 |
275 |
0.048
|
|
|
|
embryonic development via the syncytial blastoderm
|
GO:0001700 |
148 |
0.046
|
|
|
|
histone modification
|
GO:0016570 |
106 |
0.045
|
|
|
|
autophagic cell death
|
GO:0048102 |
83 |
0.045
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
103 |
0.045
|
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
256 |
0.045
|
|
|
|
chromosome segregation
|
GO:0007059 |
157 |
0.044
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
89 |
0.044
|
|
|
|
dna metabolic process
|
GO:0006259 |
227 |
0.043
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
3 |
0.043
|
|
|
|
histone h3 k4 methylation
|
GO:0051568 |
16 |
0.042
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
106 |
0.041
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
107 |
0.039
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
291 |
0.039
|
|
|
|
phosphorylation
|
GO:0016310 |
294 |
0.038
|
|
|
|
rna localization
|
GO:0006403 |
115 |
0.038
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
130 |
0.035
|
|
|
|
cell motility
|
GO:0048870 |
251 |
0.035
|
|
|
|
mapk cascade
|
GO:0000165 |
107 |
0.035
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
3 |
0.035
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
57 |
0.032
|
|
|
|
response to other organism
|
GO:0051707 |
293 |
0.031
|
|
|
|
protein secretion
|
GO:0009306 |
45 |
0.031
|
|
|
|
cell adhesion
|
GO:0007155 |
136 |
0.030
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
130 |
0.030
|
|
|
|
mitotic spindle organization
|
GO:0007052 |
220 |
0.030
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
414 |
0.030
|
|
|
|
protein alkylation
|
GO:0008213 |
43 |
0.030
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
223 |
0.029
|
|
|
|
developmental growth
|
GO:0048589 |
280 |
0.029
|
|
|
|
response to light stimulus
|
GO:0009416 |
124 |
0.029
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
90 |
0.029
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
118 |
0.028
|
|
|
|
localization of cell
|
GO:0051674 |
257 |
0.028
|
|
|
|
salivary gland histolysis
|
GO:0035070 |
88 |
0.027
|
|
|
|
eye development
|
GO:0001654 |
323 |
0.027
|
Zebrafish |
|
|
intracellular signal transduction
|
GO:0035556 |
300 |
0.025
|
|
|
|
regulation of cell death
|
GO:0010941 |
173 |
0.025
|
|
|
|
camera type eye morphogenesis
|
GO:0048593 |
2 |
0.025
|
|
|
|
establishment of localization in cell
|
GO:0051649 |
402 |
0.024
|
|
|
|
histone lysine methylation
|
GO:0034968 |
32 |
0.024
|
|
|
|
regulation of cell shape
|
GO:0008360 |
113 |
0.023
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
69 |
0.023
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
196 |
0.023
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
243 |
0.023
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
105 |
0.023
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
167 |
0.023
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
323 |
0.022
|
|
|
|
chromatin organization
|
GO:0006325 |
207 |
0.022
|
|
|
|
chromosome localization
|
GO:0050000 |
20 |
0.022
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
152 |
0.022
|
|
|
|
stem cell division
|
GO:0017145 |
69 |
0.021
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
302 |
0.021
|
|
|
|
positive regulation of molecular function
|
GO:0044093 |
136 |
0.021
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
34 |
0.021
|
|
|
|
epithelial cell migration
|
GO:0010631 |
148 |
0.021
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
297 |
0.021
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
258 |
0.021
|
|
|
|
cellular response to chemical stimulus
|
GO:0070887 |
199 |
0.021
|
Yeast |
|
|
actin cytoskeleton organization
|
GO:0030036 |
206 |
0.020
|
|
|
|
response to bacterium
|
GO:0009617 |
198 |
0.020
|
|
|
|
response to lipid
|
GO:0033993 |
38 |
0.020
|
|
|
|
muscle cell development
|
GO:0055001 |
50 |
0.019
|
|
|
|
regulation of response to stress
|
GO:0080134 |
200 |
0.019
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
61 |
0.019
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
185 |
0.019
|
|
|
|
eye morphogenesis
|
GO:0048592 |
260 |
0.018
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
242 |
0.018
|
|
|
|
cell division
|
GO:0051301 |
248 |
0.018
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
109 |
0.018
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
24 |
0.018
|
|
|
|
central nervous system development
|
GO:0007417 |
201 |
0.017
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
103 |
0.017
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
21 |
0.017
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
397 |
0.017
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
21 |
0.017
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
34 |
0.017
|
|
|
|
endomembrane system organization
|
GO:0010256 |
119 |
0.017
|
|
|
|
dorsal ventral axis specification
|
GO:0009950 |
66 |
0.016
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
223 |
0.016
|
|
|
|
muscle organ development
|
GO:0007517 |
127 |
0.016
|
|
|
|
defense response to other organism
|
GO:0098542 |
225 |
0.016
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
100 |
0.016
|
|
|
|
immune system process
|
GO:0002376 |
347 |
0.016
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
4 |
0.016
|
Zebrafish |
|
|
regulation of phosphorylation
|
GO:0042325 |
147 |
0.016
|
|
|
|
apoptotic process
|
GO:0006915 |
159 |
0.016
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
190 |
0.016
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
65 |
0.016
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
143 |
0.016
|
|
|
|
protein acylation
|
GO:0043543 |
42 |
0.016
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
0 |
0.016
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
153 |
0.015
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
250 |
0.015
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
210 |
0.015
|
|
|
|
heart contraction
|
GO:0060047 |
26 |
0.015
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
1 |
0.015
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
140 |
0.014
|
|
|
|
tube morphogenesis
|
GO:0035239 |
191 |
0.014
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
28 |
0.014
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
181 |
0.014
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
260 |
0.014
|
|
|
|
imaginal disc derived leg morphogenesis
|
GO:0007480 |
80 |
0.014
|
|
|
|
regulation of cell division
|
GO:0051302 |
72 |
0.014
|
|
|
|
tube development
|
GO:0035295 |
244 |
0.014
|
|
|
|
organonitrogen compound metabolic process
|
GO:1901564 |
318 |
0.013
|
|
|
|
cell fate determination
|
GO:0001709 |
91 |
0.013
|
|
|
|
organic substance transport
|
GO:0071702 |
257 |
0.013
|
|
|
|
imaginal disc derived wing morphogenesis
|
GO:0007476 |
337 |
0.013
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
93 |
0.013
|
|
|
|
positive regulation of gene expression epigenetic
|
GO:0045815 |
16 |
0.013
|
|
|
|
stem cell proliferation
|
GO:0072089 |
88 |
0.013
|
|
|
|
respiratory system development
|
GO:0060541 |
213 |
0.013
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
58 |
0.012
|
|
|
|
establishment of chromosome localization
|
GO:0051303 |
20 |
0.012
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
58 |
0.012
|
|
|
|
proteolysis
|
GO:0006508 |
192 |
0.012
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
206 |
0.012
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
87 |
0.012
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
89 |
0.012
|
|
|
|
protein complex assembly
|
GO:0006461 |
200 |
0.012
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
3 |
0.012
|
|
|
|
cell cycle comprising mitosis without cytokinesis
|
GO:0033301 |
25 |
0.012
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
4 |
0.012
|
|
|
|
growth
|
GO:0040007 |
359 |
0.012
|
|
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
210 |
0.012
|
|
|
|
regulation of protein modification process
|
GO:0031399 |
112 |
0.011
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
68 |
0.011
|
|
|
|
circulatory system process
|
GO:0003013 |
37 |
0.011
|
|
|
|
cell maturation
|
GO:0048469 |
144 |
0.011
|
|
|
|
actin filament based process
|
GO:0030029 |
220 |
0.011
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
47 |
0.011
|
|
|
|
positive regulation of catalytic activity
|
GO:0043085 |
118 |
0.011
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
108 |
0.011
|
|
|
|
metaphase plate congression
|
GO:0051310 |
19 |
0.011
|
|
|
|
methylation
|
GO:0032259 |
47 |
0.011
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
95 |
0.011
|
|
|
|
connective tissue development
|
GO:0061448 |
3 |
0.011
|
|
|
|
phagocytosis
|
GO:0006909 |
215 |
0.011
|
|
|
|
regionalization
|
GO:0003002 |
416 |
0.010
|
|
|
|
stem cell development
|
GO:0048864 |
79 |
0.010
|
|
|
|
regulation of dna replication
|
GO:0006275 |
13 |
0.010
|
|
|
|
leg disc morphogenesis
|
GO:0007478 |
80 |
0.010
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
78 |
0.010
|
|
|
|
biological adhesion
|
GO:0022610 |
138 |
0.010
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
3 |
0.010
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
210 |
0.010
|
|