Drosophila melanogaster

147 known processes

twi (Dmel_CG2956)

twist

(Aliases: CG2956,TWI,Twi,dip5,bHLHb17,Dmel\CG2956,EC9,DTwist)

twi biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle structure development GO:0061061 224 0.998
circulatory system development GO:0072359 82 0.977
Human Mouse Fly
tube development GO:0035295 244 0.971
heart development GO:0007507 82 0.967
Human Mouse Fly
ventral furrow formation GO:0007370 17 0.966
malpighian tubule morphogenesis GO:0007443 44 0.925
embryonic hindgut morphogenesis GO:0048619 48 0.916
muscle organ development GO:0007517 127 0.907
mesoderm development GO:0007498 78 0.888
urogenital system development GO:0001655 72 0.856
renal system development GO:0072001 72 0.834
malpighian tubule development GO:0072002 64 0.831
tube morphogenesis GO:0035239 191 0.830
cardioblast differentiation GO:0010002 20 0.829
muscle cell differentiation GO:0042692 103 0.809
hindgut morphogenesis GO:0007442 58 0.805
salivary gland development GO:0007431 162 0.794
digestive tract development GO:0048565 149 0.767
neuron recognition GO:0008038 101 0.754
Fly
mesoderm morphogenesis GO:0048332 22 0.750
cardiovascular system development GO:0072358 82 0.730
Human Mouse Fly
eye development GO:0001654 323 0.728
Human Mouse Fly
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.727
gastrulation involving germ band extension GO:0010004 36 0.715
negative regulation of gene expression GO:0010629 387 0.708
salivary gland morphogenesis GO:0007435 145 0.704
hematopoietic or lymphoid organ development GO:0048534 57 0.703
Mouse Fly
regionalization GO:0003002 416 0.695
Fly
embryonic pattern specification GO:0009880 174 0.680
mesoderm formation GO:0001707 21 0.673
gastrulation with mouth forming first GO:0001703 36 0.668
cell projection assembly GO:0030031 94 0.648
digestive tract morphogenesis GO:0048546 127 0.643
localization of cell GO:0051674 257 0.623
Human Mouse
gland morphogenesis GO:0022612 145 0.622
negative regulation of rna metabolic process GO:0051253 251 0.613
Human Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.612
positive regulation of rna biosynthetic process GO:1902680 266 0.603
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.596
negative regulation of transcription dna templated GO:0045892 237 0.583
Human Mouse
embryonic morphogenesis GO:0048598 206 0.579
nephrocyte differentiation GO:0061319 12 0.579
hemopoiesis GO:0030097 46 0.571
Mouse Fly
determination of bilateral symmetry GO:0009855 13 0.557
cardiac cell fate commitment GO:0060911 17 0.547
positive regulation of transcription dna templated GO:0045893 266 0.532
immune system development GO:0002520 57 0.525
Mouse Fly
digestive system development GO:0055123 149 0.517
actin cytoskeleton organization GO:0030036 206 0.508
somatic muscle development GO:0007525 66 0.508
regulation of muscle organ development GO:0048634 13 0.500
regulation of multicellular organismal development GO:2000026 414 0.490
mesodermal cell differentiation GO:0048333 7 0.478
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.477
Human Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.475
Human Mouse
cardioblast cell fate commitment GO:0042684 14 0.472
immune system process GO:0002376 347 0.444
Mouse Fly
eye photoreceptor cell fate commitment GO:0042706 37 0.433
Fly
renal tubule development GO:0061326 64 0.424
enzyme linked receptor protein signaling pathway GO:0007167 179 0.410
Fly
gland development GO:0048732 191 0.409
cardiocyte differentiation GO:0035051 29 0.405
Mouse
head development GO:0060322 135 0.402
Mouse Fly
striated muscle cell development GO:0055002 50 0.402
regulation of cell differentiation GO:0045595 302 0.397
Human Mouse
torso signaling pathway GO:0008293 21 0.397
muscle cell development GO:0055001 50 0.397
cell fate determination GO:0001709 91 0.394
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.387
positive regulation of nucleic acid templated transcription GO:1903508 266 0.384
respiratory system development GO:0060541 213 0.376
regulation of developmental growth GO:0048638 174 0.370
heart morphogenesis GO:0003007 32 0.370
Mouse
eye morphogenesis GO:0048592 260 0.360
Human Fly
cell recognition GO:0008037 102 0.353
Fly
apoptotic process GO:0006915 159 0.351
Mouse Rat Fly
gonadal mesoderm development GO:0007506 8 0.343
single organism behavior GO:0044708 391 0.341
Fly
gliogenesis GO:0042063 80 0.337
negative regulation of developmental process GO:0051093 201 0.332
Human Mouse
transcription from rna polymerase ii promoter GO:0006366 368 0.328
morphogenesis of an epithelium GO:0002009 276 0.325
organ formation GO:0048645 39 0.323
Fly
ameboidal type cell migration GO:0001667 151 0.315
Mouse
renal tubule morphogenesis GO:0061333 44 0.315
epithelial cell migration open tracheal system GO:0007427 32 0.314
intracellular signal transduction GO:0035556 300 0.310
Human
negative regulation of biosynthetic process GO:0009890 277 0.305
Human Mouse
sensory organ morphogenesis GO:0090596 260 0.294
Human Fly
cell migration GO:0016477 238 0.289
Mouse
imaginal disc derived appendage development GO:0048737 399 0.289
Fly
anterior posterior pattern specification GO:0009952 136 0.286
nephron epithelium development GO:0072009 3 0.285
compound eye morphogenesis GO:0001745 249 0.284
Fly
growth GO:0040007 359 0.281
formation of primary germ layer GO:0001704 24 0.278
establishment of localization in cell GO:0051649 402 0.278
Human
axon development GO:0061564 297 0.273
kidney development GO:0001822 3 0.269
cell fate commitment involved in formation of primary germ layer GO:0060795 10 0.267
regulation of cell proliferation GO:0042127 163 0.266
Mouse Rat
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.262
Human Mouse
developmental growth GO:0048589 280 0.262
multi multicellular organism process GO:0044706 123 0.256
Worm Fly
positive regulation of macromolecule metabolic process GO:0010604 405 0.255
organelle assembly GO:0070925 198 0.251
developmental pigmentation GO:0048066 68 0.250
hindgut development GO:0061525 58 0.249
actomyosin structure organization GO:0031032 56 0.246
sensory perception of sound GO:0007605 56 0.244
Fly
negative regulation of rna biosynthetic process GO:1902679 240 0.243
Human Mouse
regulation of anatomical structure morphogenesis GO:0022603 242 0.241
Human Mouse
cell surface receptor signaling pathway involved in heart development GO:0061311 3 0.238
spiracle morphogenesis open tracheal system GO:0035277 22 0.237
lymph gland development GO:0048542 28 0.236
blastoderm segmentation GO:0007350 159 0.234
regulation of localization GO:0032879 275 0.233
Human Mouse
regulation of phosphate metabolic process GO:0019220 210 0.231
Human
locomotory behavior GO:0007626 176 0.230
Fly
kidney epithelium development GO:0072073 3 0.228
striated muscle cell differentiation GO:0051146 90 0.221
regulation of cell morphogenesis GO:0022604 163 0.220
Human Mouse
ovarian follicle cell development GO:0030707 248 0.219
epithelial cell differentiation GO:0030855 322 0.217
epithelial cell development GO:0002064 274 0.214
mesodermal cell migration GO:0008078 7 0.214
actin filament based process GO:0030029 220 0.213
wing disc morphogenesis GO:0007472 344 0.212
imaginal disc derived wing morphogenesis GO:0007476 337 0.212
phosphorylation GO:0016310 294 0.211
Human
neuroepithelial cell differentiation GO:0060563 6 0.211
compound eye development GO:0048749 307 0.207
Fly
synapse assembly GO:0007416 143 0.206
positive regulation of phosphate metabolic process GO:0045937 139 0.201
reproductive system development GO:0061458 74 0.199
epithelial tube morphogenesis GO:0060562 88 0.191
negative regulation of multicellular organismal process GO:0051241 142 0.191
Human Mouse
multicellular organismal reproductive behavior GO:0033057 110 0.191
Worm Fly
smoothened signaling pathway GO:0007224 49 0.191
Fly
germ cell migration GO:0008354 43 0.187
imaginal disc derived appendage morphogenesis GO:0035114 395 0.187
Fly
positive regulation of cellular component organization GO:0051130 156 0.183
Human Mouse
sensory perception of mechanical stimulus GO:0050954 72 0.180
Fly
embryonic heart tube development GO:0035050 22 0.179
Fly
genital disc development GO:0035215 44 0.178
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.178
trachea morphogenesis GO:0060439 22 0.176
negative regulation of nucleic acid templated transcription GO:1903507 240 0.175
Human Mouse
mesenchymal cell differentiation GO:0048762 1 0.175
Human Mouse
positive regulation of response to stimulus GO:0048584 323 0.173
dna endoreduplication GO:0042023 22 0.172
mesodermal cell fate specification GO:0007501 2 0.171
Worm
cell motility GO:0048870 251 0.167
Human Mouse
adult behavior GO:0030534 137 0.166
cell fate commitment involved in pattern specification GO:0060581 31 0.165
Fly
positive regulation of cellular biosynthetic process GO:0031328 316 0.163
glial cell migration GO:0008347 31 0.162
segmentation GO:0035282 207 0.161
regulation of immune system process GO:0002682 176 0.155
Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.154
Human Mouse
sensory organ precursor cell fate determination GO:0016360 19 0.154
Fly
positive regulation of gene expression GO:0010628 290 0.153
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.151
Human Mouse
regulation of developmental pigmentation GO:0048070 24 0.150
camera type eye development GO:0043010 4 0.147
Human Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.147
larval development GO:0002164 104 0.145
Fly
columnar cuboidal epithelial cell development GO:0002066 249 0.145
cell fate specification GO:0001708 71 0.143
Worm
pericardial nephrocyte differentiation GO:0061320 9 0.142
pigmentation GO:0043473 75 0.142
tissue migration GO:0090130 155 0.141
lipid metabolic process GO:0006629 121 0.141
Human
negative regulation of response to stimulus GO:0048585 258 0.139
Human Mouse
regulation of mitotic cell cycle GO:0007346 190 0.139
stem cell differentiation GO:0048863 117 0.139
Human Mouse
homeostatic process GO:0042592 199 0.138
appendage morphogenesis GO:0035107 397 0.138
Mouse Fly
negative regulation of cellular metabolic process GO:0031324 382 0.137
Human Mouse
skin development GO:0043588 65 0.137
post embryonic appendage morphogenesis GO:0035120 385 0.136
positive regulation of rna metabolic process GO:0051254 271 0.135
gastrulation GO:0007369 70 0.134
multicellular organism growth GO:0035264 46 0.134
regulation of catalytic activity GO:0050790 185 0.134
response to abiotic stimulus GO:0009628 341 0.134
Human Mouse
regulation of molecular function GO:0065009 217 0.133
Human Mouse
cellular component assembly involved in morphogenesis GO:0010927 151 0.130
embryonic axis specification GO:0000578 107 0.129
small molecule metabolic process GO:0044281 305 0.127
Human
brain development GO:0007420 120 0.127
Fly
limb development GO:0060173 1 0.125
Mouse
endocytosis GO:0006897 310 0.125
death GO:0016265 284 0.124
Mouse Rat Fly
regulation of organelle organization GO:0033043 196 0.122
Human Mouse
morphogenesis of embryonic epithelium GO:0016331 94 0.122
Mouse
single organism biosynthetic process GO:0044711 206 0.122
negative regulation of cell communication GO:0010648 223 0.120
Human Mouse
regulation of cell fate specification GO:0042659 27 0.118
synapse organization GO:0050808 196 0.118
developmental growth involved in morphogenesis GO:0060560 65 0.117
positive regulation of developmental process GO:0051094 143 0.116
Human Mouse
embryo development ending in birth or egg hatching GO:0009792 152 0.116
Human Zebrafish Mouse
outflow tract morphogenesis GO:0003151 4 0.116
Mouse
eye photoreceptor cell differentiation GO:0001754 145 0.114
Fly
axonogenesis GO:0007409 290 0.114
bmp signaling pathway GO:0030509 27 0.113
visceral muscle development GO:0007522 14 0.113
Fly
vesicle mediated transport GO:0016192 381 0.113
cell division GO:0051301 248 0.113
cellular amine metabolic process GO:0044106 12 0.113
larval visceral muscle development GO:0007523 9 0.112
regulation of heart morphogenesis GO:2000826 3 0.111
Mouse
negative regulation of signal transduction GO:0009968 206 0.109
Human Mouse
positive regulation of biosynthetic process GO:0009891 316 0.108
g protein coupled receptor signaling pathway GO:0007186 136 0.108
telencephalon development GO:0021537 2 0.108
positive regulation of catalytic activity GO:0043085 118 0.108
gonad development GO:0008406 50 0.108
germarium derived egg chamber formation GO:0007293 101 0.108
cellular response to chemical stimulus GO:0070887 199 0.107
Human Mouse Rat
sex differentiation GO:0007548 81 0.107
membrane organization GO:0061024 112 0.105
epithelial cell migration GO:0010631 148 0.105
development of primary sexual characteristics GO:0045137 50 0.104
forebrain development GO:0030900 2 0.103
negative regulation of cell differentiation GO:0045596 143 0.102
Human Mouse
exocrine system development GO:0035272 162 0.102
muscle attachment GO:0016203 36 0.099
open tracheal system development GO:0007424 204 0.099
sensory perception GO:0007600 196 0.099
Fly
appendage development GO:0048736 401 0.098
Mouse Fly
regulation of synapse organization GO:0050807 110 0.096
determination of left right symmetry GO:0007368 9 0.094
negative regulation of signaling GO:0023057 219 0.094
Human Mouse
branching involved in open tracheal system development GO:0060446 45 0.094
cell death GO:0008219 279 0.094
Mouse Rat Fly
nucleobase containing small molecule metabolic process GO:0055086 174 0.093
heart formation GO:0060914 6 0.092
nephron tubule morphogenesis GO:0072078 3 0.092
developmental maturation GO:0021700 172 0.092
limb morphogenesis GO:0035108 1 0.091
Mouse
regulation of response to stress GO:0080134 200 0.090
Human
cell proliferation GO:0008283 299 0.089
Human Mouse Rat
regulation of intracellular signal transduction GO:1902531 236 0.089
Human
regulation of programmed cell death GO:0043067 152 0.089
Mouse Rat Fly
formation of anatomical boundary GO:0048859 37 0.089
Fly
terminal region determination GO:0007362 25 0.087
cellular catabolic process GO:0044248 372 0.087
Human
anterior posterior pattern specification imaginal disc GO:0007448 16 0.086
male mating behavior GO:0060179 70 0.086
Fly
regulation of organ formation GO:0003156 3 0.086
cardioblast cell fate specification GO:0042685 9 0.085
skeletal muscle fiber development GO:0048741 3 0.085
regulation of cell development GO:0060284 215 0.084
Human Mouse
imaginal disc pattern formation GO:0007447 91 0.084
regulation of dna templated transcription elongation GO:0032784 17 0.083
Fly
renal filtration cell differentiation GO:0061318 12 0.083
striated muscle tissue development GO:0014706 27 0.082
negative regulation of dna endoreduplication GO:0032876 2 0.082
ectodermal placode morphogenesis GO:0071697 4 0.082
cell growth GO:0016049 108 0.082
positive regulation of intracellular signal transduction GO:1902533 116 0.081
segment specification GO:0007379 33 0.081
neuron projection guidance GO:0097485 241 0.080
regulation of apoptotic process GO:0042981 130 0.080
Mouse Rat Fly
nephron morphogenesis GO:0072028 3 0.080
cellular response to nutrient levels GO:0031669 62 0.079
regulation of anatomical structure size GO:0090066 163 0.079
regulation of cell fate commitment GO:0010453 29 0.079
cell migration involved in gastrulation GO:0042074 9 0.079
axon guidance GO:0007411 233 0.079
regulation of transport GO:0051049 181 0.077
Human Mouse
developmental programmed cell death GO:0010623 138 0.077
neuron projection extension GO:1990138 32 0.077
developmental induction GO:0031128 3 0.077
immune response GO:0006955 246 0.076
multi organism behavior GO:0051705 175 0.075
Worm Fly
extrinsic apoptotic signaling pathway GO:0097191 1 0.074
negative regulation of apoptotic process GO:0043066 63 0.074
Mouse Rat Fly
defense response to other organism GO:0098542 225 0.074
programmed cell death GO:0012501 257 0.074
Mouse Rat Fly
cardiac muscle tissue development GO:0048738 9 0.073
purine ribonucleotide metabolic process GO:0009150 145 0.073
response to external biotic stimulus GO:0043207 293 0.073
response to biotic stimulus GO:0009607 294 0.073
nephron development GO:0072006 3 0.072
circulatory system process GO:0003013 37 0.072
motor neuron axon guidance GO:0008045 58 0.072
organic acid metabolic process GO:0006082 103 0.071
Human
organelle localization GO:0051640 148 0.070
positive regulation of transferase activity GO:0051347 26 0.070
organic substance catabolic process GO:1901575 308 0.070
Human
signal transduction by phosphorylation GO:0023014 107 0.070
tracheal outgrowth open tracheal system GO:0007426 18 0.069
ribonucleotide metabolic process GO:0009259 145 0.068
negative regulation of developmental growth GO:0048640 64 0.068
wnt signaling pathway GO:0016055 98 0.068
regulation of cardioblast differentiation GO:0051890 9 0.068
chromosome organization GO:0051276 360 0.067
Human Mouse
response to transforming growth factor beta GO:0071559 18 0.067
organ induction GO:0001759 3 0.067
nucleoside phosphate metabolic process GO:0006753 162 0.067
negative regulation of cell cycle process GO:0010948 109 0.066
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.066
regulation of multicellular organism growth GO:0040014 40 0.066
establishment of protein localization GO:0045184 163 0.066
Human
body morphogenesis GO:0010171 2 0.066
Mouse
myotube cell development GO:0014904 3 0.066
ribonucleoside catabolic process GO:0042454 112 0.065
defense response GO:0006952 300 0.065
positive regulation of programmed cell death GO:0043068 62 0.065
positive regulation of signaling GO:0023056 243 0.065
tissue morphogenesis GO:0048729 297 0.065
oocyte differentiation GO:0009994 145 0.064
substrate dependent cell migration GO:0006929 3 0.064
cellular response to organic substance GO:0071310 132 0.064
Rat
cellular response to growth factor stimulus GO:0071363 30 0.064
Rat
negative regulation of epithelial cell proliferation GO:0050680 4 0.064
branching morphogenesis of an epithelial tube GO:0048754 45 0.064
organophosphate metabolic process GO:0019637 195 0.064
chorion containing eggshell formation GO:0007304 105 0.063
response to lipid GO:0033993 38 0.063
regulation of stem cell proliferation GO:0072091 40 0.063
phagocytosis GO:0006909 215 0.063
regulation of epithelial cell proliferation GO:0050678 4 0.062
Mouse Rat
positive regulation of cell communication GO:0010647 250 0.062
cardiac cell fate specification GO:0060912 10 0.061
aging GO:0007568 143 0.061
Human
organonitrogen compound metabolic process GO:1901564 318 0.061
positive regulation of cellular amine metabolic process GO:0033240 0 0.061
chemotaxis GO:0006935 249 0.060
cell cell signaling involved in cell fate commitment GO:0045168 210 0.060
myofibril assembly GO:0030239 36 0.060
anterior posterior axis specification embryo GO:0008595 103 0.060
response to nutrient levels GO:0031667 114 0.060
male courtship behavior veined wing vibration GO:0016545 21 0.059
Fly
larval somatic muscle development GO:0007526 19 0.059
dorsal ventral pattern formation GO:0009953 133 0.059
response to other organism GO:0051707 293 0.059
nucleoside triphosphate metabolic process GO:0009141 120 0.059
specification of symmetry GO:0009799 13 0.058
filopodium assembly GO:0046847 33 0.058
mesenchyme development GO:0060485 9 0.058
Human Mouse
lamellipodium organization GO:0097581 21 0.057
oxoacid metabolic process GO:0043436 103 0.057
Human
central nervous system development GO:0007417 201 0.056
Fly
reproductive behavior GO:0019098 122 0.056
Worm Fly
apoptotic process involved in morphogenesis GO:0060561 3 0.056
regulation of synapse structure and activity GO:0050803 128 0.056
vesicle localization GO:0051648 55 0.055
protein modification process GO:0036211 438 0.054
Human Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.054
Fly
ovarian follicle cell migration GO:0007297 121 0.054
connective tissue development GO:0061448 3 0.054
regulation of reproductive process GO:2000241 54 0.054
single organism catabolic process GO:0044712 228 0.053
Human
regulation of protein metabolic process GO:0051246 256 0.053
Human Mouse
cellular protein complex assembly GO:0043623 71 0.053
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.053
embryonic development via the syncytial blastoderm GO:0001700 148 0.052
amine metabolic process GO:0009308 12 0.052
epidermis development GO:0008544 65 0.052
trachea development GO:0060438 29 0.052
nucleoside phosphate catabolic process GO:1901292 110 0.052
purine ribonucleotide catabolic process GO:0009154 109 0.052
camera type eye morphogenesis GO:0048593 2 0.052
Human
taxis GO:0042330 304 0.052
nephron tubule development GO:0072080 3 0.052
cell maturation GO:0048469 144 0.052
humoral immune response GO:0006959 117 0.051
single organism cellular localization GO:1902580 180 0.051
dna replication GO:0006260 48 0.050
mesodermal cell fate commitment GO:0001710 7 0.050
lamellipodium assembly GO:0030032 21 0.050
regulation of cellular component biogenesis GO:0044087 201 0.050
protein transport GO:0015031 155 0.050
Human
response to organic substance GO:0010033 284 0.050
Rat
cellular ketone metabolic process GO:0042180 24 0.049
Human
regulation of organ morphogenesis GO:2000027 78 0.049
Mouse
negative regulation of cell cycle GO:0045786 116 0.049
cognition GO:0050890 141 0.049
cell cell junction assembly GO:0007043 38 0.049
positive regulation of developmental growth GO:0048639 62 0.049
negative regulation of cell fate specification GO:0009996 15 0.048
regulation of cell death GO:0010941 173 0.048
Mouse Rat Fly
positive regulation of hydrolase activity GO:0051345 78 0.048
regulation of embryonic cell shape GO:0016476 30 0.048
positive regulation of cell death GO:0010942 69 0.048
regulation of phosphorylation GO:0042325 147 0.048
Human
neuroblast differentiation GO:0014016 29 0.048
post embryonic hemopoiesis GO:0035166 17 0.047
regulation of phosphorus metabolic process GO:0051174 210 0.047
Human
organic substance transport GO:0071702 257 0.047
Human
catabolic process GO:0009056 409 0.047
Human
reproductive structure development GO:0048608 74 0.047
positive regulation of phosphorus metabolic process GO:0010562 139 0.047
muscle tissue morphogenesis GO:0060415 2 0.047
synaptic transmission GO:0007268 288 0.046
positive regulation of lipid metabolic process GO:0045834 4 0.046
Human
regulation of cell shape GO:0008360 113 0.046
negative regulation of cellular biosynthetic process GO:0031327 277 0.046
Human Mouse
response to wounding GO:0009611 94 0.046
carboxylic acid metabolic process GO:0019752 92 0.045
Human
negative regulation of growth GO:0045926 84 0.045
locomotor rhythm GO:0045475 56 0.045
Fly
ribose phosphate metabolic process GO:0019693 145 0.045
nucleoside metabolic process GO:0009116 127 0.045
positive regulation of immune system process GO:0002684 68 0.045
organelle fission GO:0048285 340 0.044
regulation of ras protein signal transduction GO:0046578 93 0.044
determination of muscle attachment site GO:0016204 7 0.043
eye pigmentation GO:0048069 43 0.043
developmental cell growth GO:0048588 52 0.043
negative regulation of cell death GO:0060548 81 0.043
Mouse Rat Fly
purine containing compound metabolic process GO:0072521 155 0.043
cell cycle dna replication GO:0044786 23 0.043
mesenchymal cell development GO:0014031 1 0.043
Human Mouse
spinal cord dorsal ventral patterning GO:0021513 1 0.043
nucleotide metabolic process GO:0009117 161 0.043
regulation of hydrolase activity GO:0051336 97 0.043
canonical wnt signaling pathway GO:0060070 21 0.042
regulation of membrane potential GO:0042391 35 0.042
dna templated transcription elongation GO:0006354 18 0.042
Fly
negative regulation of organelle organization GO:0010639 56 0.041
Human Mouse
morphogenesis of a branching epithelium GO:0061138 45 0.041
embryonic digestive tract development GO:0048566 5 0.041
border follicle cell migration GO:0007298 113 0.041
regulation of embryonic development GO:0045995 68 0.041
regulation of bmp signaling pathway GO:0030510 23 0.040
lateral inhibition GO:0046331 206 0.040
embryonic epithelial tube formation GO:0001838 6 0.040
Mouse
regulation of smoothened signaling pathway GO:0008589 28 0.040
spermatogenesis GO:0007283 200 0.039
protein modification by small protein conjugation GO:0032446 79 0.039
regulation of axonogenesis GO:0050770 32 0.039
response to hypoxia GO:0001666 53 0.039
Human Mouse
macromolecular complex assembly GO:0065003 256 0.039
tripartite regional subdivision GO:0007351 103 0.038
protein phosphorylation GO:0006468 169 0.038
Human
axis specification GO:0009798 167 0.038
organic hydroxy compound metabolic process GO:1901615 83 0.038
cholesterol homeostasis GO:0042632 3 0.038
synaptic growth at neuromuscular junction GO:0051124 119 0.038
striated muscle myosin thick filament assembly GO:0071688 3 0.037
regulation of cell growth GO:0001558 43 0.037
positive regulation of multicellular organismal process GO:0051240 143 0.037
Human Mouse
mitotic nuclear division GO:0007067 213 0.037
ecdysone mediated induction of salivary gland cell autophagic cell death GO:0035072 12 0.037
cellular nitrogen compound catabolic process GO:0044270 165 0.036
nephron epithelium morphogenesis GO:0072088 3 0.036
small gtpase mediated signal transduction GO:0007264 88 0.036
regulation of transferase activity GO:0051338 58 0.036
single organism intracellular transport GO:1902582 207 0.036
response to endogenous stimulus GO:0009719 119 0.036
tube fusion GO:0035146 17 0.035
cellular macromolecule localization GO:0070727 220 0.035
embryonic organ development GO:0048568 50 0.035
Human Mouse Fly
positive regulation of muscle organ development GO:0048636 6 0.035
positive regulation of neuron apoptotic process GO:0043525 1 0.035
olfactory behavior GO:0042048 97 0.035
mapk cascade GO:0000165 107 0.035
mating behavior GO:0007617 106 0.034
Fly
chemical homeostasis GO:0048878 92 0.034
regulation of dna metabolic process GO:0051052 34 0.034
Human
response to organic cyclic compound GO:0014070 89 0.034
response to growth factor GO:0070848 31 0.034
Rat
secretion GO:0046903 109 0.033
Human
sarcomere organization GO:0045214 26 0.033
oocyte development GO:0048599 124 0.033
positive regulation of cellular component biogenesis GO:0044089 80 0.033
regulation of kinase activity GO:0043549 53 0.033
regulation of cell cycle GO:0051726 291 0.032
ectodermal placode development GO:0071696 4 0.032
positive regulation of signal transduction GO:0009967 223 0.032
epidermal cell differentiation GO:0009913 51 0.032
anterior posterior axis specification GO:0009948 109 0.032
nucleobase containing compound catabolic process GO:0034655 165 0.032
positive regulation of nervous system development GO:0051962 69 0.032
regulation of cell cycle process GO:0010564 181 0.031
negative regulation of cardioblast differentiation GO:0051892 7 0.031
retina development in camera type eye GO:0060041 4 0.031
regulation of striated muscle tissue development GO:0016202 5 0.031
embryonic digestive tract morphogenesis GO:0048557 4 0.031
epithelial cell proliferation involved in renal tubule morphogenesis GO:2001013 11 0.031
vesicle organization GO:0016050 44 0.031
regulation of canonical wnt signaling pathway GO:0060828 15 0.031
negative regulation of smoothened signaling pathway GO:0045879 16 0.031
axon extension GO:0048675 32 0.031
neuroblast fate specification GO:0014018 2 0.031

twi disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.075
Human
cardiovascular system disease DOID:1287 0 0.075
cancer DOID:162 0 0.034
disease of cellular proliferation DOID:14566 0 0.034
organ system cancer DOID:0050686 0 0.034
musculoskeletal system disease DOID:17 0 0.033
Human