Drosophila melanogaster

107 known processes

Xbp1 (Dmel_CG9415)

X box binding protein-1

(Aliases: XBP-1,138/3,CG 9415,Xbp-1,clone 1.41,Dxbp-1,xbp1,CG9415,anon-EST:Liang-1.41,l(2)k13803,xbp-1,Dmel\CG9415,XBP1)

Xbp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 103 0.489
small molecule metabolic process GO:0044281 305 0.454
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.430
negative regulation of autophagy GO:0010507 16 0.428
organonitrogen compound metabolic process GO:1901564 318 0.409
embryonic morphogenesis GO:0048598 206 0.353
cellular catabolic process GO:0044248 372 0.329
Mouse
cell migration GO:0016477 238 0.319
regulation of localization GO:0032879 275 0.291
Mouse
carboxylic acid metabolic process GO:0019752 92 0.284
homeostatic process GO:0042592 199 0.272
Mouse
regulation of macroautophagy GO:0016241 15 0.267
glycosyl compound catabolic process GO:1901658 112 0.252
establishment of localization in cell GO:0051649 402 0.232
Mouse
carbohydrate derivative metabolic process GO:1901135 217 0.230
gland morphogenesis GO:0022612 145 0.218
Mouse
response to radiation GO:0009314 155 0.201
meiotic cell cycle GO:0051321 171 0.194
peptide metabolic process GO:0006518 80 0.191
death GO:0016265 284 0.183
Mouse
ribonucleotide metabolic process GO:0009259 145 0.183
response to nutrient levels GO:0031667 114 0.179
spermatogenesis GO:0007283 200 0.166
organic acid metabolic process GO:0006082 103 0.165
autophagy GO:0006914 108 0.165
negative regulation of gene expression GO:0010629 387 0.164
positive regulation of transcription dna templated GO:0045893 266 0.163
vesicle mediated transport GO:0016192 381 0.162
positive regulation of developmental process GO:0051094 143 0.156
Mouse
digestive tract development GO:0048565 149 0.144
developmental maturation GO:0021700 172 0.144
Mouse
protein localization GO:0008104 284 0.142
Mouse
organic substance transport GO:0071702 257 0.140
Mouse
imaginal disc derived appendage morphogenesis GO:0035114 395 0.139
ribose phosphate metabolic process GO:0019693 145 0.137
single organism intracellular transport GO:1902582 207 0.135
translation GO:0006412 69 0.132
negative regulation of cellular catabolic process GO:0031330 34 0.130
lipid homeostasis GO:0055088 33 0.129
negative regulation of cellular metabolic process GO:0031324 382 0.126
purine containing compound catabolic process GO:0072523 112 0.124
regulation of autophagy GO:0010506 62 0.121
ribonucleoside metabolic process GO:0009119 127 0.119
regulation of cellular localization GO:0060341 136 0.117
Mouse
secretion by cell GO:0032940 101 0.117
Mouse
organic substance catabolic process GO:1901575 308 0.113
Mouse
catabolic process GO:0009056 409 0.113
Mouse
gastrulation GO:0007369 70 0.111
cuticle development GO:0042335 86 0.103
cellular amide metabolic process GO:0043603 80 0.101
regulation of cellular catabolic process GO:0031329 157 0.100
Mouse
receptor mediated endocytosis GO:0006898 21 0.097
regionalization GO:0003002 416 0.095
cell motility GO:0048870 251 0.091
regulation of catabolic process GO:0009894 170 0.090
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 266 0.086
wing disc morphogenesis GO:0007472 344 0.086
protein transport GO:0015031 155 0.083
Mouse
organelle fission GO:0048285 340 0.081
tube morphogenesis GO:0035239 191 0.080
response to abiotic stimulus GO:0009628 341 0.080
localization of cell GO:0051674 257 0.079
cellular response to abiotic stimulus GO:0071214 58 0.077
positive regulation of cell communication GO:0010647 250 0.077
purine nucleoside triphosphate catabolic process GO:0009146 108 0.077
establishment of protein localization GO:0045184 163 0.077
Mouse
mitotic nuclear division GO:0007067 213 0.077
regulation of transport GO:0051049 181 0.076
Mouse
response to organic substance GO:0010033 284 0.074
cell division GO:0051301 248 0.071
morphogenesis of embryonic epithelium GO:0016331 94 0.071
digestive system development GO:0055123 149 0.071
Mouse
cellular macromolecule localization GO:0070727 220 0.070
single organism biosynthetic process GO:0044711 206 0.070
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.069
imaginal disc derived wing morphogenesis GO:0007476 337 0.068
positive regulation of lipid metabolic process GO:0045834 4 0.067
tissue morphogenesis GO:0048729 297 0.067
negative regulation of biosynthetic process GO:0009890 277 0.065
aging GO:0007568 143 0.064
Worm
single organism catabolic process GO:0044712 228 0.064
chromosome organization GO:0051276 360 0.064
positive regulation of biosynthetic process GO:0009891 316 0.063
cellular amino acid metabolic process GO:0006520 61 0.063
endosome transport via multivesicular body sorting pathway GO:0032509 12 0.058
endocytosis GO:0006897 310 0.058
axon guidance GO:0007411 233 0.057
negative regulation of catabolic process GO:0009895 36 0.057
negative regulation of transcription dna templated GO:0045892 237 0.057
synaptic growth at neuromuscular junction GO:0051124 119 0.056
male gamete generation GO:0048232 201 0.056
cellular ketone metabolic process GO:0042180 24 0.056
response to external biotic stimulus GO:0043207 293 0.054
Mouse
heterocycle catabolic process GO:0046700 166 0.054
wing disc pattern formation GO:0035222 66 0.052
cytoplasmic transport GO:0016482 130 0.051
organophosphate metabolic process GO:0019637 195 0.051
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.051
nucleotide catabolic process GO:0009166 109 0.051
regulation of developmental growth GO:0048638 174 0.049
malpighian tubule development GO:0072002 64 0.049
embryo development ending in birth or egg hatching GO:0009792 152 0.047
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.047
gastrulation with mouth forming first GO:0001703 36 0.046
neuron projection guidance GO:0097485 241 0.046
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.046
digestive tract morphogenesis GO:0048546 127 0.046
striated muscle cell differentiation GO:0051146 90 0.045
nucleotide metabolic process GO:0009117 161 0.045
ribonucleoside catabolic process GO:0042454 112 0.045
response to light stimulus GO:0009416 124 0.045
carbohydrate metabolic process GO:0005975 82 0.044
cellular response to topologically incorrect protein GO:0035967 10 0.044
positive regulation of rna biosynthetic process GO:1902680 266 0.044
morphogenesis of an epithelium GO:0002009 276 0.044
carbohydrate derivative catabolic process GO:1901136 118 0.044
purine containing compound metabolic process GO:0072521 155 0.043
cellular protein localization GO:0034613 160 0.043
purine nucleoside metabolic process GO:0042278 127 0.042
positive regulation of macromolecule metabolic process GO:0010604 405 0.042
positive regulation of cellular biosynthetic process GO:0031328 316 0.042
nuclear division GO:0000280 332 0.042
purine ribonucleotide metabolic process GO:0009150 145 0.041
nucleoside triphosphate metabolic process GO:0009141 120 0.041
ameboidal type cell migration GO:0001667 151 0.041
response to other organism GO:0051707 293 0.040
Mouse
protein secretion GO:0009306 45 0.039
Mouse
macroautophagy GO:0016236 42 0.039
mitotic cytokinesis GO:0000281 50 0.038
nucleobase containing small molecule metabolic process GO:0055086 174 0.037
positive regulation of response to stimulus GO:0048584 323 0.036
multicellular organismal aging GO:0010259 140 0.036
Worm
nucleoside triphosphate catabolic process GO:0009143 108 0.036
purine nucleotide metabolic process GO:0006163 146 0.035
central nervous system development GO:0007417 201 0.034
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.034
dorsal ventral pattern formation GO:0009953 133 0.034
guanosine containing compound metabolic process GO:1901068 74 0.034
regulation of programmed cell death GO:0043067 152 0.034
Mouse
secretion GO:0046903 109 0.033
Mouse
sensory organ morphogenesis GO:0090596 260 0.033
respiratory system development GO:0060541 213 0.033
purine nucleoside triphosphate metabolic process GO:0009144 119 0.032
glycosyl compound metabolic process GO:1901657 127 0.032
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.032
positive regulation of cell differentiation GO:0045597 64 0.032
purine ribonucleoside metabolic process GO:0046128 127 0.032
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.032
dendrite morphogenesis GO:0048813 199 0.032
positive regulation of transport GO:0051050 92 0.031
Mouse
positive regulation of multicellular organismal process GO:0051240 143 0.031
Mouse
brain development GO:0007420 120 0.031
body morphogenesis GO:0010171 2 0.031
eye development GO:0001654 323 0.030
epithelium migration GO:0090132 148 0.030
ncrna metabolic process GO:0034660 43 0.029
salivary gland morphogenesis GO:0007435 145 0.029
regulation of notch signaling pathway GO:0008593 100 0.029
negative regulation of signaling GO:0023057 219 0.029
epithelial tube morphogenesis GO:0060562 88 0.029
lipid storage GO:0019915 38 0.028
tissue migration GO:0090130 155 0.028
purine nucleotide catabolic process GO:0006195 109 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.028
single organism behavior GO:0044708 391 0.028
cellular response to nutrient levels GO:0031669 62 0.027
nucleoside metabolic process GO:0009116 127 0.027
regulation of organelle organization GO:0033043 196 0.027
regulation of secretion by cell GO:1903530 39 0.027
Mouse
intracellular protein transport GO:0006886 104 0.027
dendrite development GO:0016358 204 0.027
regulation of cell differentiation GO:0045595 302 0.027
amino acid activation GO:0043038 3 0.027
muscle cell differentiation GO:0042692 103 0.026
imaginal disc derived appendage development GO:0048737 399 0.026
regulation of embryonic development GO:0045995 68 0.026
organelle membrane fusion GO:0090174 16 0.026
neurological system process GO:0050877 358 0.026
multi organism behavior GO:0051705 175 0.025
tube development GO:0035295 244 0.025
negative regulation of growth of symbiont involved in interaction with host GO:0044146 9 0.025
membrane organization GO:0061024 112 0.024
response to extracellular stimulus GO:0009991 116 0.024
negative regulation of mitotic cell cycle GO:0045930 109 0.024
multicellular organismal reproductive behavior GO:0033057 110 0.024
regulation of response to nutrient levels GO:0032107 18 0.024
ribonucleoside triphosphate metabolic process GO:0009199 119 0.024
cellular response to extracellular stimulus GO:0031668 64 0.023
vesicle organization GO:0016050 44 0.023
single organism cellular localization GO:1902580 180 0.023
regulation of response to extracellular stimulus GO:0032104 18 0.022
spindle organization GO:0007051 253 0.022
cholesterol homeostasis GO:0042632 3 0.021
exocrine system development GO:0035272 162 0.021
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 108 0.021
cardiocyte differentiation GO:0035051 29 0.021
nucleobase containing compound catabolic process GO:0034655 165 0.020
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.020
macromolecule deacylation GO:0098732 11 0.020
enzyme linked receptor protein signaling pathway GO:0007167 179 0.020
cellular protein catabolic process GO:0044257 83 0.020
Mouse
negative regulation of cell communication GO:0010648 223 0.020
regulation of phosphatase activity GO:0010921 3 0.020
cellular nitrogen compound catabolic process GO:0044270 165 0.020
organonitrogen compound catabolic process GO:1901565 128 0.019
positive regulation of signaling GO:0023056 243 0.019
positive regulation of rna metabolic process GO:0051254 271 0.019
fatty acid homeostasis GO:0055089 2 0.019
guanosine containing compound catabolic process GO:1901069 74 0.019
eye morphogenesis GO:0048592 260 0.019
circulatory system development GO:0072359 82 0.019
centrosome organization GO:0051297 163 0.019
defense response to gram negative bacterium GO:0050829 94 0.019
positive regulation of cell death GO:0010942 69 0.019
chemotaxis GO:0006935 249 0.019
compound eye development GO:0048749 307 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.018
purine ribonucleoside catabolic process GO:0046130 112 0.018
compound eye morphogenesis GO:0001745 249 0.018
reproductive behavior GO:0019098 122 0.018
regulation of cell death GO:0010941 173 0.018
Mouse
multicellular organismal homeostasis GO:0048871 41 0.018
taxis GO:0042330 304 0.018
peptidyl amino acid modification GO:0018193 105 0.018
positive regulation of secretion by cell GO:1903532 20 0.018
Mouse
sister chromatid segregation GO:0000819 92 0.017
organelle localization GO:0051640 148 0.017
growth of symbiont involved in interaction with host GO:0044116 9 0.017
meiotic nuclear division GO:0007126 151 0.017
regulation of protein complex disassembly GO:0043244 29 0.017
regulation of anatomical structure size GO:0090066 163 0.017
single organism membrane organization GO:0044802 93 0.017
stem cell differentiation GO:0048863 117 0.017
protein modification process GO:0036211 438 0.017
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.017
ribonucleotide catabolic process GO:0009261 109 0.016
regulation of cell cycle process GO:0010564 181 0.016
organic cyclic compound catabolic process GO:1901361 168 0.016
imaginal disc pattern formation GO:0007447 91 0.016
single organism membrane budding GO:1902591 2 0.016
cation transport GO:0006812 110 0.016
appendage morphogenesis GO:0035107 397 0.016
cell death GO:0008219 279 0.016
Mouse
lipid metabolic process GO:0006629 121 0.016
cholesterol transport GO:0030301 2 0.016
developmental pigmentation GO:0048066 68 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.016
gastrulation involving germ band extension GO:0010004 36 0.016
regulation of growth GO:0040008 233 0.016
transcription from rna polymerase ii promoter GO:0006366 368 0.015
negative regulation of developmental process GO:0051093 201 0.015
embryonic development via the syncytial blastoderm GO:0001700 148 0.015
regulation of cell division GO:0051302 72 0.015
cell maturation GO:0048469 144 0.015
Mouse
post embryonic appendage morphogenesis GO:0035120 385 0.015
wing disc dorsal ventral pattern formation GO:0048190 47 0.015
salivary gland development GO:0007431 162 0.015
Mouse
positive regulation of cell development GO:0010720 61 0.015
regulation of multicellular organismal development GO:2000026 414 0.015
Mouse
regulation of anatomical structure morphogenesis GO:0022603 242 0.015
Mouse
positive regulation of cell proliferation GO:0008284 47 0.015
Mouse
gtp metabolic process GO:0046039 72 0.015
metal ion homeostasis GO:0055065 44 0.014
positive regulation of programmed cell death GO:0043068 62 0.014
trna processing GO:0008033 3 0.014
eye pigmentation GO:0048069 43 0.014
positive regulation of gene expression GO:0010628 290 0.014
epithelial cell migration GO:0010631 148 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.014
modulation of growth of symbiont involved in interaction with host GO:0044144 9 0.014
regulation of vesicle mediated transport GO:0060627 59 0.013
trna aminoacylation GO:0043039 2 0.013
cellular response to organic substance GO:0071310 132 0.013
negative regulation of organelle organization GO:0010639 56 0.013
axon development GO:0061564 297 0.013
instar larval development GO:0002168 55 0.013
autophagic vacuole assembly GO:0000045 2 0.013
open tracheal system development GO:0007424 204 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.012
positive regulation of lipid biosynthetic process GO:0046889 3 0.012
single organism carbohydrate metabolic process GO:0044723 72 0.012
notch signaling pathway GO:0007219 120 0.012
cellular response to radiation GO:0071478 52 0.012
cellular response to external stimulus GO:0071496 66 0.012
mitotic cell cycle phase transition GO:0044772 138 0.012
programmed cell death GO:0012501 257 0.012
Mouse
axonogenesis GO:0007409 290 0.012
head development GO:0060322 135 0.011
anatomical structure homeostasis GO:0060249 97 0.011
defense response to bacterium GO:0042742 178 0.011
proteasomal protein catabolic process GO:0010498 59 0.011
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.011
Mouse
nitrogen compound transport GO:0071705 85 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.011
larval development GO:0002164 104 0.011
Worm
response to bacterium GO:0009617 198 0.011
Mouse
regulation of multi organism process GO:0043900 131 0.011
rna processing GO:0006396 147 0.011
regulation of organ morphogenesis GO:2000027 78 0.011
Mouse
mating behavior GO:0007617 106 0.011
appendage development GO:0048736 401 0.011
maintenance of cell polarity GO:0030011 18 0.011
pigment biosynthetic process GO:0046148 36 0.011
cytoskeleton dependent intracellular transport GO:0030705 44 0.011
protein catabolic process GO:0030163 101 0.010
Mouse
ion transport GO:0006811 145 0.010
negative regulation of protein processing GO:0010955 31 0.010
regulation of response to stress GO:0080134 200 0.010
response to alcohol GO:0097305 95 0.010
exocytosis GO:0006887 28 0.010
sterol homeostasis GO:0055092 4 0.010
negative regulation of cell division GO:0051782 17 0.010
developmental programmed cell death GO:0010623 138 0.010
proteolysis GO:0006508 192 0.010
Mouse
gland development GO:0048732 191 0.010
Zebrafish Mouse
positive regulation of cellular component organization GO:0051130 156 0.010
actin cytoskeleton reorganization GO:0031532 22 0.010
cellular response to unfolded protein GO:0034620 9 0.010

Xbp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.127
inherited metabolic disorder DOID:655 0 0.127
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.017