Drosophila melanogaster

132 known processes

zwilch (Dmel_CG18729)

CG18729 gene product from transcript CG18729-RA

(Aliases: Dmel\CG18729,CG18639,CG18729,Zwilch)

zwilch biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
reciprocal meiotic recombination GO:0007131 19 0.960
nuclear division GO:0000280 332 0.936
organelle fission GO:0048285 340 0.883
meiotic nuclear division GO:0007126 151 0.765
chromosome segregation GO:0007059 157 0.617
meiotic chromosome segregation GO:0045132 59 0.550
meiotic cell cycle process GO:1903046 132 0.451
cell division GO:0051301 248 0.446
male meiosis GO:0007140 52 0.398
chromosome separation GO:0051304 42 0.379
reciprocal dna recombination GO:0035825 19 0.348
mitotic nuclear division GO:0007067 213 0.324
regulation of cell cycle phase transition GO:1901987 130 0.265
chromosome organization GO:0051276 360 0.257
dna metabolic process GO:0006259 227 0.242
meiotic cell cycle GO:0051321 171 0.222
female meiotic division GO:0007143 70 0.213
cellular catabolic process GO:0044248 372 0.176
dna packaging GO:0006323 91 0.142
dna recombination GO:0006310 32 0.130
catabolic process GO:0009056 409 0.114
meiosis i GO:0007127 59 0.104
establishment of localization in cell GO:0051649 402 0.091
centrosome cycle GO:0007098 137 0.087
organelle localization GO:0051640 148 0.084
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.082
mitotic spindle organization GO:0007052 220 0.079
regulation of cell cycle process GO:0010564 181 0.078
resolution of meiotic recombination intermediates GO:0000712 6 0.075
mitotic sister chromatid segregation GO:0000070 87 0.072
ubiquitin dependent protein catabolic process GO:0006511 78 0.072
centrosome organization GO:0051297 163 0.071
spindle organization GO:0007051 253 0.064
regulation of organelle organization GO:0033043 196 0.063
protein localization GO:0008104 284 0.063
regulation of mitotic cell cycle phase transition GO:1901990 130 0.062
regulation of mitosis GO:0007088 56 0.056
asymmetric cell division GO:0008356 37 0.055
organelle assembly GO:0070925 198 0.055
regulation of cell division GO:0051302 72 0.052
regulation of mitotic sister chromatid segregation GO:0033047 28 0.050
female meiosis chromosome segregation GO:0016321 33 0.048
macromolecule catabolic process GO:0009057 161 0.047
aromatic compound catabolic process GO:0019439 166 0.045
cellular macromolecule catabolic process GO:0044265 136 0.043
organic substance catabolic process GO:1901575 308 0.040
female meiosis i GO:0007144 8 0.040
sister chromatid segregation GO:0000819 92 0.038
spindle assembly GO:0051225 80 0.038
regulation of mitotic cell cycle GO:0007346 190 0.038
negative regulation of mitotic cell cycle GO:0045930 109 0.038
mitotic cell cycle phase transition GO:0044772 138 0.037
protein transport GO:0015031 155 0.037
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.037
mitotic cytokinesis GO:0000281 50 0.037
proteasomal protein catabolic process GO:0010498 59 0.037
negative regulation of gene expression GO:0010629 387 0.036
single fertilization GO:0007338 24 0.035
mitotic sister chromatid separation GO:0051306 30 0.035
regulation of mitotic sister chromatid separation GO:0010965 28 0.035
macromolecular complex assembly GO:0065003 256 0.034
negative regulation of cellular metabolic process GO:0031324 382 0.033
positive regulation of catabolic process GO:0009896 105 0.033
negative regulation of rna biosynthetic process GO:1902679 240 0.033
heterocycle catabolic process GO:0046700 166 0.033
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.033
regulation of nuclear division GO:0051783 58 0.033
single organism cellular localization GO:1902580 180 0.033
positive regulation of catalytic activity GO:0043085 118 0.032
modification dependent macromolecule catabolic process GO:0043632 79 0.032
microtubule anchoring GO:0034453 11 0.032
single organism intracellular transport GO:1902582 207 0.032
regulation of phosphate metabolic process GO:0019220 210 0.031
endomembrane system organization GO:0010256 119 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.031
chromosome condensation GO:0030261 41 0.030
chromatin remodeling GO:0006338 72 0.030
spindle assembly involved in female meiosis i GO:0007057 5 0.029
cell death GO:0008219 279 0.029
regulation of ras protein signal transduction GO:0046578 93 0.029
cell fate determination GO:0001709 91 0.029
dna replication GO:0006260 48 0.028
single organism catabolic process GO:0044712 228 0.028
double strand break repair GO:0006302 26 0.028
organic substance transport GO:0071702 257 0.027
cytokinesis GO:0000910 90 0.027
cellular protein modification process GO:0006464 438 0.027
metaphase anaphase transition of cell cycle GO:0044784 28 0.027
organic cyclic compound catabolic process GO:1901361 168 0.026
meiotic chromosome separation GO:0051307 8 0.026
maintenance of location in cell GO:0051651 28 0.026
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.026
negative regulation of cellular biosynthetic process GO:0031327 277 0.026
positive regulation of protein transport GO:0051222 37 0.026
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.025
cellular protein localization GO:0034613 160 0.025
nucleoside phosphate metabolic process GO:0006753 162 0.025
negative regulation of cell cycle GO:0045786 116 0.024
nucleoside triphosphate metabolic process GO:0009141 120 0.024
intracellular signal transduction GO:0035556 300 0.024
nucleobase containing compound catabolic process GO:0034655 165 0.024
somatic stem cell division GO:0048103 37 0.024
regulation of proteasomal protein catabolic process GO:0061136 39 0.024
positive regulation of biosynthetic process GO:0009891 316 0.023
positive regulation of phosphate metabolic process GO:0045937 139 0.023
regulation of molecular function GO:0065009 217 0.023
ras protein signal transduction GO:0007265 88 0.023
organophosphate metabolic process GO:0019637 195 0.023
regulation of catabolic process GO:0009894 170 0.023
dna damage checkpoint GO:0000077 78 0.022
intracellular transport GO:0046907 228 0.022
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.021
dna integrity checkpoint GO:0031570 81 0.021
mitotic g2 m transition checkpoint GO:0044818 70 0.021
regulation of chromosome organization GO:0033044 64 0.021
small gtpase mediated signal transduction GO:0007264 88 0.021
negative regulation of transcription dna templated GO:0045892 237 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.020
cell cycle phase transition GO:0044770 140 0.020
purine ribonucleoside catabolic process GO:0046130 112 0.020
positive regulation of phosphorus metabolic process GO:0010562 139 0.020
cellular response to dna damage stimulus GO:0006974 223 0.020
heart development GO:0007507 82 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.020
cytoplasmic transport GO:0016482 130 0.020
muscle structure development GO:0061061 224 0.020
regulation of protein transport GO:0051223 57 0.020
purine nucleoside triphosphate metabolic process GO:0009144 119 0.019
regulation of cellular catabolic process GO:0031329 157 0.019
chromatin organization GO:0006325 207 0.019
negative regulation of nucleic acid templated transcription GO:1903507 240 0.019
ribonucleoside triphosphate metabolic process GO:0009199 119 0.019
response to alcohol GO:0097305 95 0.018
meiotic sister chromatid segregation GO:0045144 6 0.018
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.018
positive regulation of nucleoside metabolic process GO:0045979 47 0.018
asymmetric stem cell division GO:0098722 49 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.018
cell cycle checkpoint GO:0000075 95 0.017
intracellular protein transport GO:0006886 104 0.017
purine containing compound catabolic process GO:0072523 112 0.017
sensory organ morphogenesis GO:0090596 260 0.017
mating behavior GO:0007617 106 0.017
positive regulation of cell cycle process GO:0090068 28 0.017
phosphorylation GO:0016310 294 0.017
regulation of chromosome segregation GO:0051983 32 0.016
purine ribonucleotide catabolic process GO:0009154 109 0.016
nucleoside metabolic process GO:0009116 127 0.016
histone modification GO:0016570 106 0.016
negative regulation of biosynthetic process GO:0009890 277 0.016
ribonucleoside metabolic process GO:0009119 127 0.016
regulation of cellular localization GO:0060341 136 0.016
gene silencing GO:0016458 138 0.016
embryo development ending in birth or egg hatching GO:0009792 152 0.016
Worm
dna conformation change GO:0071103 105 0.016
regulation of transport GO:0051049 181 0.015
g1 s transition of mitotic cell cycle GO:0000082 31 0.015
protein catabolic process GO:0030163 101 0.015
regulation of cytoskeleton organization GO:0051493 89 0.015
vesicle mediated transport GO:0016192 381 0.015
establishment or maintenance of cell polarity GO:0007163 167 0.015
forebrain development GO:0030900 2 0.015
regulation of protein catabolic process GO:0042176 55 0.014
sex differentiation GO:0007548 81 0.014
regulation of sister chromatid segregation GO:0033045 28 0.014
purine nucleoside catabolic process GO:0006152 112 0.014
cilium morphogenesis GO:0060271 39 0.014
negative regulation of protein metabolic process GO:0051248 85 0.014
response to oxygen containing compound GO:1901700 200 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.014
glycosyl compound catabolic process GO:1901658 112 0.014
death GO:0016265 284 0.014
dna repair GO:0006281 54 0.014
cellular protein complex assembly GO:0043623 71 0.013
spindle assembly involved in mitosis GO:0090307 50 0.013
mitotic g2 dna damage checkpoint GO:0007095 69 0.013
protein phosphorylation GO:0006468 169 0.013
regulation of protein localization GO:0032880 76 0.013
open tracheal system development GO:0007424 204 0.013
cell cycle g1 s phase transition GO:0044843 31 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
positive regulation of signal transduction GO:0009967 223 0.013
establishment of protein localization to peroxisome GO:0072663 2 0.013
cellular protein catabolic process GO:0044257 83 0.013
maintenance of protein location in cell GO:0032507 26 0.013
purine containing compound metabolic process GO:0072521 155 0.013
microtubule organizing center organization GO:0031023 168 0.013
positive regulation of transport GO:0051050 92 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.013
ribose phosphate metabolic process GO:0019693 145 0.013
protein complex biogenesis GO:0070271 201 0.013
fertilization GO:0009566 26 0.012
single organism biosynthetic process GO:0044711 206 0.012
regulation of dna metabolic process GO:0051052 34 0.012
developmental growth GO:0048589 280 0.012
dna endoreduplication GO:0042023 22 0.012
cell growth GO:0016049 108 0.012
gene silencing by rna GO:0031047 57 0.012
regulation of microtubule based process GO:0032886 49 0.012
cell proliferation GO:0008283 299 0.012
organonitrogen compound metabolic process GO:1901564 318 0.012
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.012
positive regulation of cellular biosynthetic process GO:0031328 316 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
golgi organization GO:0007030 66 0.012
lateral inhibition GO:0046331 206 0.012
positive regulation of nucleotide catabolic process GO:0030813 46 0.012
anterior posterior axis specification embryo GO:0008595 103 0.012
ribonucleoside catabolic process GO:0042454 112 0.012
regulation of cell shape GO:0008360 113 0.012
positive regulation of cell communication GO:0010647 250 0.012
positive regulation of hydrolase activity GO:0051345 78 0.011
centrosome duplication GO:0051298 121 0.011
negative regulation of cell communication GO:0010648 223 0.011
organophosphate catabolic process GO:0046434 112 0.011
membrane organization GO:0061024 112 0.011
purine nucleotide catabolic process GO:0006195 109 0.011
nucleoside catabolic process GO:0009164 112 0.011
salivary gland development GO:0007431 162 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
establishment of organelle localization GO:0051656 122 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
purine ribonucleoside metabolic process GO:0046128 127 0.011
regulation of intracellular signal transduction GO:1902531 236 0.011
cellular macromolecule localization GO:0070727 220 0.011
stem cell division GO:0017145 69 0.011
positive regulation of nucleotide metabolic process GO:0045981 55 0.011
distributive segregation GO:0032837 6 0.011
homeostatic process GO:0042592 199 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.011
gland morphogenesis GO:0022612 145 0.011
regulation of ras gtpase activity GO:0032318 38 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.011
male meiosis cytokinesis GO:0007112 26 0.011
mitotic dna integrity checkpoint GO:0044774 75 0.011
compound eye development GO:0048749 307 0.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.010
proteolysis GO:0006508 192 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.010
maintenance of protein location GO:0045185 28 0.010
regulation of catalytic activity GO:0050790 185 0.010
spindle midzone assembly GO:0051255 4 0.010
regulation of establishment of protein localization GO:0070201 61 0.010
regulation of dna replication GO:0006275 13 0.010

zwilch disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.011