Drosophila melanogaster

44 known processes

Dbx (Dmel_CG42234)

CG42234 gene product from transcript CG42234-RC

(Aliases: Dmel_CG13925,dbx,dDbx,CG42234,CG12361,Dmel\CG42234,Dmel_CG12361,CG13925)

Dbx biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
motor neuron axon guidance GO:0008045 58 0.935
neuron projection guidance GO:0097485 241 0.818
chemotaxis GO:0006935 249 0.755
axon development GO:0061564 297 0.662
axon guidance GO:0007411 233 0.556
axonogenesis GO:0007409 290 0.556
taxis GO:0042330 304 0.467
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.086
central nervous system development GO:0007417 201 0.071
flight behavior GO:0007629 26 0.063
macromolecular complex assembly GO:0065003 256 0.063
adult locomotory behavior GO:0008344 76 0.058
cell proliferation GO:0008283 299 0.057
post embryonic appendage morphogenesis GO:0035120 385 0.056
imaginal disc derived appendage development GO:0048737 399 0.055
dephosphorylation GO:0016311 51 0.055
body morphogenesis GO:0010171 2 0.053
positive regulation of cell communication GO:0010647 250 0.052
eye development GO:0001654 323 0.051
negative regulation of response to stimulus GO:0048585 258 0.049
single organism behavior GO:0044708 391 0.048
locomotory behavior GO:0007626 176 0.048
cell death GO:0008219 279 0.048
small gtpase mediated signal transduction GO:0007264 88 0.046
somatic muscle development GO:0007525 66 0.045
organonitrogen compound metabolic process GO:1901564 318 0.042
regulation of nervous system development GO:0051960 248 0.041
chaeta development GO:0022416 97 0.039
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.038
appendage development GO:0048736 401 0.038
forebrain development GO:0030900 2 0.037
adult behavior GO:0030534 137 0.037
olfactory bulb axon guidance GO:0071678 3 0.037
epithelial cell differentiation GO:0030855 322 0.035
cellular macromolecular complex assembly GO:0034622 153 0.035
purine nucleoside triphosphate metabolic process GO:0009144 119 0.034
regulation of organelle organization GO:0033043 196 0.034
purine ribonucleotide catabolic process GO:0009154 109 0.034
telencephalon development GO:0021537 2 0.033
protein localization GO:0008104 284 0.032
neuron recognition GO:0008038 101 0.031
regulation of cell death GO:0010941 173 0.031
immune system process GO:0002376 347 0.031
ribonucleotide metabolic process GO:0009259 145 0.031
response to abiotic stimulus GO:0009628 341 0.031
purine ribonucleoside metabolic process GO:0046128 127 0.031
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.030
regulation of cell proliferation GO:0042127 163 0.030
regulation of anatomical structure morphogenesis GO:0022603 242 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.030
positive regulation of signal transduction GO:0009967 223 0.029
response to external biotic stimulus GO:0043207 293 0.029
regulation of cell differentiation GO:0045595 302 0.029
purine nucleoside catabolic process GO:0006152 112 0.029
appendage morphogenesis GO:0035107 397 0.028
protein modification process GO:0036211 438 0.028
muscle structure development GO:0061061 224 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.027
kidney development GO:0001822 3 0.027
programmed cell death GO:0012501 257 0.026
skin development GO:0043588 65 0.026
nucleotide metabolic process GO:0009117 161 0.025
embryonic development via the syncytial blastoderm GO:0001700 148 0.025
camera type eye development GO:0043010 4 0.024
axon choice point recognition GO:0016198 26 0.024
eye morphogenesis GO:0048592 260 0.024
cell motility GO:0048870 251 0.024
purine nucleotide metabolic process GO:0006163 146 0.024
guanosine containing compound metabolic process GO:1901068 74 0.024
regulation of catalytic activity GO:0050790 185 0.024
ras protein signal transduction GO:0007265 88 0.023
transcription from rna polymerase ii promoter GO:0006366 368 0.023
regulation of hydrolase activity GO:0051336 97 0.023
establishment of organelle localization GO:0051656 122 0.023
mitotic nuclear division GO:0007067 213 0.022
rho protein signal transduction GO:0007266 14 0.022
cellular nitrogen compound catabolic process GO:0044270 165 0.022
regulation of multicellular organismal development GO:2000026 414 0.022
endocytosis GO:0006897 310 0.021
response to biotic stimulus GO:0009607 294 0.021
nucleoside triphosphate metabolic process GO:0009141 120 0.021
defense response to other organism GO:0098542 225 0.021
positive regulation of signaling GO:0023056 243 0.021
purine ribonucleotide metabolic process GO:0009150 145 0.021
organic substance catabolic process GO:1901575 308 0.021
nucleobase containing compound catabolic process GO:0034655 165 0.021
salivary gland development GO:0007431 162 0.021
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.020
ribose phosphate metabolic process GO:0019693 145 0.020
positive regulation of nervous system development GO:0051962 69 0.020
synapse assembly GO:0007416 143 0.020
regulation of cytoskeleton organization GO:0051493 89 0.020
regulation of molecular function GO:0065009 217 0.020
nucleotide catabolic process GO:0009166 109 0.020
regionalization GO:0003002 416 0.020
protein complex assembly GO:0006461 200 0.020
cell division GO:0051301 248 0.020
nucleoside phosphate metabolic process GO:0006753 162 0.019
glycosyl compound catabolic process GO:1901658 112 0.019
nucleobase containing small molecule metabolic process GO:0055086 174 0.019
ribonucleoside triphosphate catabolic process GO:0009203 108 0.019
positive regulation of response to stimulus GO:0048584 323 0.019
organic cyclic compound catabolic process GO:1901361 168 0.019
negative regulation of signaling GO:0023057 219 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.018
nucleoside metabolic process GO:0009116 127 0.018
negative regulation of signal transduction GO:0009968 206 0.018
negative regulation of cell communication GO:0010648 223 0.018
compound eye development GO:0048749 307 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.018
heterocycle catabolic process GO:0046700 166 0.018
negative regulation of nervous system development GO:0051961 92 0.018
cellular protein complex assembly GO:0043623 71 0.018
photoreceptor cell axon guidance GO:0072499 23 0.018
regulation of intracellular signal transduction GO:1902531 236 0.018
regulation of cell substrate adhesion GO:0010810 2 0.018
carbohydrate derivative catabolic process GO:1901136 118 0.018
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.018
purine containing compound catabolic process GO:0072523 112 0.017
regulation of neurogenesis GO:0050767 158 0.017
aromatic compound catabolic process GO:0019439 166 0.017
purine nucleotide catabolic process GO:0006195 109 0.017
protein complex biogenesis GO:0070271 201 0.017
response to lipopolysaccharide GO:0032496 4 0.017
small molecule metabolic process GO:0044281 305 0.017
organic substance transport GO:0071702 257 0.017
purine nucleoside triphosphate catabolic process GO:0009146 108 0.017
regulation of photoreceptor cell axon guidance GO:2000289 5 0.017
posttranscriptional regulation of gene expression GO:0010608 145 0.017
positive regulation of cell motility GO:2000147 3 0.017
synaptic transmission GO:0007268 288 0.017
ribonucleoside triphosphate metabolic process GO:0009199 119 0.017
negative regulation of cellular metabolic process GO:0031324 382 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.017
growth GO:0040007 359 0.016
regulation of cell cycle GO:0051726 291 0.016
gland morphogenesis GO:0022612 145 0.016
ribonucleotide catabolic process GO:0009261 109 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.016
organonitrogen compound catabolic process GO:1901565 128 0.016
glycosyl compound metabolic process GO:1901657 127 0.016
regulation of ras protein signal transduction GO:0046578 93 0.016
cellular protein modification process GO:0006464 438 0.016
regulation of cellular protein metabolic process GO:0032268 243 0.016
stem cell proliferation GO:0072089 88 0.016
epidermal cell differentiation GO:0009913 51 0.016
purine nucleoside metabolic process GO:0042278 127 0.015
imaginal disc derived wing morphogenesis GO:0007476 337 0.015
response to other organism GO:0051707 293 0.015
mrna metabolic process GO:0016071 124 0.015
ribonucleoside metabolic process GO:0009119 127 0.015
photoreceptor cell development GO:0042461 96 0.015
gtp catabolic process GO:0006184 72 0.015
positive regulation of catabolic process GO:0009896 105 0.015
positive regulation of ras gtpase activity GO:0032320 36 0.015
phagocytosis GO:0006909 215 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
exocrine system development GO:0035272 162 0.015
negative regulation of cellular protein metabolic process GO:0032269 85 0.015
nucleoside phosphate catabolic process GO:1901292 110 0.015
phosphorylation GO:0016310 294 0.015
purine ribonucleoside catabolic process GO:0046130 112 0.014
positive regulation of cell differentiation GO:0045597 64 0.014
regulation of purine nucleotide catabolic process GO:0033121 48 0.014
positive regulation of hydrolase activity GO:0051345 78 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
nucleoside catabolic process GO:0009164 112 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
synapse organization GO:0050808 196 0.014
compound eye morphogenesis GO:0001745 249 0.014
protein dna complex subunit organization GO:0071824 86 0.014
cell adhesion GO:0007155 136 0.014
purine containing compound metabolic process GO:0072521 155 0.014
actin filament organization GO:0007015 126 0.014
wing disc morphogenesis GO:0007472 344 0.014
establishment of planar polarity GO:0001736 87 0.014
single organism catabolic process GO:0044712 228 0.014
epithelial cell development GO:0002064 274 0.013
regulation of rho protein signal transduction GO:0035023 20 0.013
cellular protein localization GO:0034613 160 0.013
segmentation GO:0035282 207 0.013
organelle localization GO:0051640 148 0.013
glycosaminoglycan catabolic process GO:0006027 3 0.013
biological adhesion GO:0022610 138 0.013
regulation of cell development GO:0060284 215 0.013
regulation of purine nucleotide metabolic process GO:1900542 62 0.013
hindbrain development GO:0030902 2 0.013
regulation of programmed cell death GO:0043067 152 0.013
axon midline choice point recognition GO:0016199 26 0.013
organic acid metabolic process GO:0006082 103 0.013
guanosine containing compound catabolic process GO:1901069 74 0.012
spinal cord development GO:0021510 1 0.012
regulation of gtpase activity GO:0043087 44 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.012
dorsal ventral axon guidance GO:0033563 2 0.012
cell recognition GO:0008037 102 0.012
regulation of cell morphogenesis GO:0022604 163 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
dendrite development GO:0016358 204 0.012
regulation of cell shape GO:0008360 113 0.012
negative regulation of rho protein signal transduction GO:0035024 1 0.012
rna localization GO:0006403 115 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
sensory organ morphogenesis GO:0090596 260 0.012
salivary gland morphogenesis GO:0007435 145 0.012
positive regulation of gtp catabolic process GO:0033126 43 0.012
digestive system development GO:0055123 149 0.012
regulation of response to stress GO:0080134 200 0.012
positive regulation of nucleoside metabolic process GO:0045979 47 0.011
spindle organization GO:0007051 253 0.011
nucleus localization GO:0051647 34 0.011
response to bacterium GO:0009617 198 0.011
negative regulation of cellular biosynthetic process GO:0031327 277 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
adult somatic muscle development GO:0007527 14 0.011
morphogenesis of a branching structure GO:0001763 45 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.011
respiratory system development GO:0060541 213 0.011
organophosphate catabolic process GO:0046434 112 0.011
actin cytoskeleton organization GO:0030036 206 0.011
regulation of microtubule based process GO:0032886 49 0.011
mesenchymal cell development GO:0014031 1 0.011
intracellular signal transduction GO:0035556 300 0.011
dendrite morphogenesis GO:0048813 199 0.011
vesicle mediated transport GO:0016192 381 0.011
regulation of vesicle mediated transport GO:0060627 59 0.011
neuromuscular junction development GO:0007528 149 0.011
catabolic process GO:0009056 409 0.011
gland development GO:0048732 191 0.011
regulation of cellular component size GO:0032535 98 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
regulation of axonogenesis GO:0050770 32 0.010
positive regulation of macromolecule metabolic process GO:0010604 405 0.010
regulation of phosphorylation GO:0042325 147 0.010
imaginal disc derived appendage morphogenesis GO:0035114 395 0.010
axon extension involved in axon guidance GO:0048846 10 0.010
regulation of protein metabolic process GO:0051246 256 0.010
organophosphate metabolic process GO:0019637 195 0.010
axonal defasciculation GO:0007414 12 0.010
negative regulation of multicellular organismal process GO:0051241 142 0.010
cellular macromolecule localization GO:0070727 220 0.010
regulation of neuron differentiation GO:0045664 103 0.010
salivary gland histolysis GO:0035070 88 0.010
hematopoietic progenitor cell differentiation GO:0002244 1 0.010
death GO:0016265 284 0.010
regulation of response to external stimulus GO:0032101 115 0.010

Dbx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.046
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014
nervous system disease DOID:863 0 0.014