Drosophila melanogaster

13 known processes

Rpt1 (Dmel_CG1341)

CG1341 gene product from transcript CG1341-RA

(Aliases: Dm_Rpt1,Rpt1/p48B,Dmel\CG1341,CG1341,1341,dRpt1,l(2)43Ed,l(2)05643,anon-WO0118547.90,Dmp48B,p48B)

Rpt1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteolysis GO:0006508 192 0.943
modification dependent macromolecule catabolic process GO:0043632 79 0.942
Human Yeast
catabolic process GO:0009056 409 0.882
Human Yeast
cellular macromolecule catabolic process GO:0044265 136 0.881
Human Yeast
protein complex assembly GO:0006461 200 0.869
Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.852
Human Yeast
positive regulation of proteolysis GO:0045862 52 0.839
modification dependent protein catabolic process GO:0019941 78 0.818
Human Yeast
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.817
positive regulation of peptidase activity GO:0010952 29 0.779
protein complex biogenesis GO:0070271 201 0.751
Yeast
cellular catabolic process GO:0044248 372 0.742
Human Yeast
nuclear division GO:0000280 332 0.720
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.718
regulation of endopeptidase activity GO:0052548 36 0.713
ubiquitin dependent protein catabolic process GO:0006511 78 0.706
Human Yeast
aging GO:0007568 143 0.704
Worm
positive regulation of endopeptidase activity GO:0010950 26 0.650
cellular response to dna damage stimulus GO:0006974 223 0.611
cellular protein catabolic process GO:0044257 83 0.602
Human Yeast
determination of adult lifespan GO:0008340 137 0.596
Worm
regulation of proteolysis GO:0030162 87 0.570
mitotic spindle organization GO:0007052 220 0.544
proteasomal protein catabolic process GO:0010498 59 0.502
regulation of cellular component biogenesis GO:0044087 201 0.490
Yeast
multicellular organismal aging GO:0010259 140 0.469
Worm
macromolecular complex assembly GO:0065003 256 0.454
Yeast
organic substance catabolic process GO:1901575 308 0.446
Human Yeast
regulation of peptidase activity GO:0052547 39 0.436
spindle organization GO:0007051 253 0.401
spindle assembly GO:0051225 80 0.391
cell death GO:0008219 279 0.377
apoptotic process GO:0006915 159 0.371
programmed cell death GO:0012501 257 0.363
cellular protein complex assembly GO:0043623 71 0.363
Yeast
transcription from rna polymerase ii promoter GO:0006366 368 0.350
Yeast
regulation of cellular protein metabolic process GO:0032268 243 0.340
mitotic spindle elongation GO:0000022 81 0.338
proteasome assembly GO:0043248 2 0.327
Yeast
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.319
organelle fission GO:0048285 340 0.312
macromolecule catabolic process GO:0009057 161 0.307
Human Yeast
protein catabolic process GO:0030163 101 0.298
Human Yeast
dna templated transcription elongation GO:0006354 18 0.288
cellular nitrogen compound catabolic process GO:0044270 165 0.280
Human
negative regulation of cellular metabolic process GO:0031324 382 0.265
regulation of proteasomal protein catabolic process GO:0061136 39 0.251
death GO:0016265 284 0.244
chromosome organization GO:0051276 360 0.243
cellular macromolecular complex assembly GO:0034622 153 0.238
Yeast
chromosome segregation GO:0007059 157 0.214
ribonucleoside monophosphate catabolic process GO:0009158 39 0.213
Human
positive regulation of nucleic acid templated transcription GO:1903508 266 0.208
Yeast
spindle assembly involved in mitosis GO:0090307 50 0.205
er associated ubiquitin dependent protein catabolic process GO:0030433 3 0.203
mitotic nuclear division GO:0007067 213 0.197
embryo development ending in birth or egg hatching GO:0009792 152 0.181
Worm
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.178
dna metabolic process GO:0006259 227 0.164
regulation of cellular ketone metabolic process GO:0010565 3 0.161
larval development GO:0002164 104 0.158
Worm
response to organic substance GO:0010033 284 0.152
positive regulation of cellular protein metabolic process GO:0032270 118 0.152
purine nucleoside catabolic process GO:0006152 112 0.148
Human
organelle assembly GO:0070925 198 0.140
dna templated transcription initiation GO:0006352 25 0.138
Yeast
aromatic compound catabolic process GO:0019439 166 0.135
Human
nucleobase containing compound catabolic process GO:0034655 165 0.132
Human
positive regulation of cellular component biogenesis GO:0044089 80 0.132
Yeast
cell motility GO:0048870 251 0.132
positive regulation of protein metabolic process GO:0051247 128 0.131
Yeast
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.131
regulation of cell cycle GO:0051726 291 0.129
positive regulation of cellular biosynthetic process GO:0031328 316 0.127
Yeast
regulation of cellular catabolic process GO:0031329 157 0.126
sister chromatid segregation GO:0000819 92 0.126
regulation of phosphate metabolic process GO:0019220 210 0.124
positive regulation of rna biosynthetic process GO:1902680 266 0.121
Yeast
dna repair GO:0006281 54 0.119
cell proliferation GO:0008283 299 0.118
negative regulation of gene expression GO:0010629 387 0.116
spindle elongation GO:0051231 83 0.113
negative regulation of signaling GO:0023057 219 0.112
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.111
Yeast
cell division GO:0051301 248 0.110
heterocycle catabolic process GO:0046700 166 0.109
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.107
Yeast
regulation of mitosis GO:0007088 56 0.107
positive regulation of macromolecule metabolic process GO:0010604 405 0.105
Yeast
ribonucleoside metabolic process GO:0009119 127 0.104
Human
negative regulation of biosynthetic process GO:0009890 277 0.101
regulation of protein metabolic process GO:0051246 256 0.100
Yeast
regulation of cell division GO:0051302 72 0.100
regulation of cell cycle process GO:0010564 181 0.095
nucleoside triphosphate catabolic process GO:0009143 108 0.092
Human
positive regulation of hydrolase activity GO:0051345 78 0.090
rna catabolic process GO:0006401 37 0.088
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.088
Yeast
purine ribonucleoside catabolic process GO:0046130 112 0.085
Human
positive regulation of biosynthetic process GO:0009891 316 0.085
Yeast
regulation of cell death GO:0010941 173 0.084
regulation of molecular function GO:0065009 217 0.083
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.083
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.081
Human
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.078
purine nucleoside monophosphate metabolic process GO:0009126 50 0.077
Human
purine nucleoside triphosphate metabolic process GO:0009144 119 0.077
Human
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.076
Yeast
chemotaxis GO:0006935 249 0.075
positive regulation of molecular function GO:0044093 136 0.075
regulation of catalytic activity GO:0050790 185 0.075
negative regulation of cell communication GO:0010648 223 0.073
regulation of cellular protein catabolic process GO:1903362 44 0.072
positive regulation of cellular catabolic process GO:0031331 95 0.072
nucleoside metabolic process GO:0009116 127 0.071
Human
negative regulation of signal transduction GO:0009968 206 0.071
phosphorylation GO:0016310 294 0.071
regulation of catabolic process GO:0009894 170 0.069
Yeast
regulation of hydrolase activity GO:0051336 97 0.066
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.066
taxis GO:0042330 304 0.065
regulation of dna templated transcription elongation GO:0032784 17 0.064
regulation of phosphorus metabolic process GO:0051174 210 0.064
cellular ketone metabolic process GO:0042180 24 0.064
ribonucleotide catabolic process GO:0009261 109 0.062
Human
intracellular signal transduction GO:0035556 300 0.062
purine nucleoside triphosphate catabolic process GO:0009146 108 0.061
Human
positive regulation of cell death GO:0010942 69 0.060
regulation of nuclear division GO:0051783 58 0.060
carbohydrate derivative catabolic process GO:1901136 118 0.060
Human
embryonic morphogenesis GO:0048598 206 0.060
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.058
positive regulation of cellular component organization GO:0051130 156 0.055
Yeast
single organism catabolic process GO:0044712 228 0.054
Human
lipid modification GO:0030258 24 0.054
tube development GO:0035295 244 0.054
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.053
Human
chromatin organization GO:0006325 207 0.053
ribonucleoside monophosphate metabolic process GO:0009161 51 0.052
Human
nucleotide metabolic process GO:0009117 161 0.051
Human
regulation of apoptotic process GO:0042981 130 0.051
positive regulation of programmed cell death GO:0043068 62 0.051
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 1 0.051
Yeast
autophagy GO:0006914 108 0.049
purine nucleotide metabolic process GO:0006163 146 0.048
Human
ribose phosphate metabolic process GO:0019693 145 0.047
Human
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 20 0.047
Yeast
positive regulation of catalytic activity GO:0043085 118 0.047
nucleoside catabolic process GO:0009164 112 0.047
Human
camera type eye development GO:0043010 4 0.047
microtubule organizing center organization GO:0031023 168 0.046
mitotic cell cycle phase transition GO:0044772 138 0.045
negative regulation of multicellular organismal process GO:0051241 142 0.045
carbohydrate derivative metabolic process GO:1901135 217 0.045
Human
cell migration GO:0016477 238 0.045
telencephalon development GO:0021537 2 0.044
protein dna complex assembly GO:0065004 63 0.044
Yeast
dna templated transcriptional preinitiation complex assembly GO:0070897 20 0.042
Yeast
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.042
Human
mitotic sister chromatid separation GO:0051306 30 0.041
regulation of mitotic cell cycle GO:0007346 190 0.041
biological adhesion GO:0022610 138 0.040
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.040
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.039
positive regulation of transcription dna templated GO:0045893 266 0.039
Yeast
epithelial cell differentiation GO:0030855 322 0.038
nucleotide excision repair GO:0006289 8 0.038
regulation of programmed cell death GO:0043067 152 0.037
purine ribonucleotide metabolic process GO:0009150 145 0.037
Human
response to oxygen containing compound GO:1901700 200 0.037
regulation of phosphorylation GO:0042325 147 0.037
glycosyl compound catabolic process GO:1901658 112 0.037
Human
sensory organ morphogenesis GO:0090596 260 0.036
regulation of response to stress GO:0080134 200 0.036
organophosphate metabolic process GO:0019637 195 0.036
Human
negative regulation of transcription dna templated GO:0045892 237 0.035
response to nitrogen compound GO:1901698 90 0.035
regulation of multicellular organismal development GO:2000026 414 0.035
response to endogenous stimulus GO:0009719 119 0.035
chromatin remodeling GO:0006338 72 0.035
forebrain development GO:0030900 2 0.034
response to biotic stimulus GO:0009607 294 0.034
centrosome organization GO:0051297 163 0.034
spinal cord development GO:0021510 1 0.034
chromatin modification GO:0016568 147 0.033
positive regulation of phosphorus metabolic process GO:0010562 139 0.033
appendage morphogenesis GO:0035107 397 0.033
purine containing compound metabolic process GO:0072521 155 0.033
Human
imaginal disc derived wing morphogenesis GO:0007476 337 0.033
negative regulation of cell proliferation GO:0008285 69 0.033
nucleoside monophosphate metabolic process GO:0009123 52 0.033
Human
purine nucleoside metabolic process GO:0042278 127 0.032
Human
purine nucleoside monophosphate catabolic process GO:0009128 38 0.031
Human
phagocytosis GO:0006909 215 0.031
tissue morphogenesis GO:0048729 297 0.031
protein dna complex subunit organization GO:0071824 86 0.030
Yeast
negative regulation of rna biosynthetic process GO:1902679 240 0.030
purine ribonucleotide catabolic process GO:0009154 109 0.030
Human
regulation of mitotic sister chromatid segregation GO:0033047 28 0.029
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 8 0.029
mitotic sister chromatid segregation GO:0000070 87 0.028
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.028
atp metabolic process GO:0046034 49 0.028
Human
regulation of cell differentiation GO:0045595 302 0.028
regulation of protein complex assembly GO:0043254 42 0.028
Yeast
response to other organism GO:0051707 293 0.028
sex differentiation GO:0007548 81 0.027
synapse organization GO:0050808 196 0.027
nucleoside phosphate metabolic process GO:0006753 162 0.027
Human
cell cycle phase transition GO:0044770 140 0.026
ribonucleoside triphosphate catabolic process GO:0009203 108 0.025
Human
protein ubiquitination GO:0016567 70 0.025
mrna cis splicing via spliceosome GO:0045292 1 0.025
organic cyclic compound catabolic process GO:1901361 168 0.025
Human
morphogenesis of an epithelium GO:0002009 276 0.025
homeostatic process GO:0042592 199 0.025
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.024
response to organonitrogen compound GO:0010243 75 0.024
organic substance transport GO:0071702 257 0.024
cell adhesion GO:0007155 136 0.024
nucleoside phosphate catabolic process GO:1901292 110 0.024
Human
tube morphogenesis GO:0035239 191 0.024
cellular lipid metabolic process GO:0044255 83 0.024
response to organic cyclic compound GO:0014070 89 0.023
meiotic cell cycle GO:0051321 171 0.023
ras protein signal transduction GO:0007265 88 0.022
cellular response to chemical stimulus GO:0070887 199 0.022
body morphogenesis GO:0010171 2 0.022
single organism behavior GO:0044708 391 0.022
negative regulation of protein metabolic process GO:0051248 85 0.022
double strand break repair GO:0006302 26 0.022
cell maturation GO:0048469 144 0.022
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.021
Yeast
mapk cascade GO:0000165 107 0.021
positive regulation of apoptotic signaling pathway GO:2001235 4 0.021
lipid metabolic process GO:0006629 121 0.021
nucleoside triphosphate metabolic process GO:0009141 120 0.021
Human
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.021
regulation of chromosome segregation GO:0051983 32 0.020
small molecule metabolic process GO:0044281 305 0.020
Human
regulation of immune system process GO:0002682 176 0.020
developmental maturation GO:0021700 172 0.020
protein processing GO:0016485 68 0.020
wing disc morphogenesis GO:0007472 344 0.020
appendage development GO:0048736 401 0.020
negative regulation of rna metabolic process GO:0051253 251 0.020
regulation of ras protein signal transduction GO:0046578 93 0.020
positive regulation of apoptotic process GO:0043065 47 0.020
glycosyl compound metabolic process GO:1901657 127 0.020
Human
regulation of organelle organization GO:0033043 196 0.019
regulation of protein catabolic process GO:0042176 55 0.019
Yeast
positive regulation of gene expression GO:0010628 290 0.019
Yeast
protein maturation GO:0051604 71 0.019
small gtpase mediated signal transduction GO:0007264 88 0.019
regulation of cell proliferation GO:0042127 163 0.019
immune system process GO:0002376 347 0.019
ribonucleoside catabolic process GO:0042454 112 0.019
Human
regulation of response to biotic stimulus GO:0002831 63 0.019
response to starvation GO:0042594 97 0.018
ribonucleoside triphosphate metabolic process GO:0009199 119 0.018
Human
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.018
Human
response to extracellular stimulus GO:0009991 116 0.018
regulation of organ morphogenesis GO:2000027 78 0.018
carboxylic acid metabolic process GO:0019752 92 0.018
protein neddylation GO:0045116 5 0.018
protein import into nucleus GO:0006606 51 0.018
positive regulation of response to stimulus GO:0048584 323 0.018
cellular response to extracellular stimulus GO:0031668 64 0.018
male gamete generation GO:0048232 201 0.017
lateral inhibition GO:0046331 206 0.017
positive regulation of phosphate metabolic process GO:0045937 139 0.017
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.017
positive regulation of signal transduction GO:0009967 223 0.017
purine ribonucleoside metabolic process GO:0046128 127 0.017
Human
regulation of localization GO:0032879 275 0.017
eye development GO:0001654 323 0.017
regulation of protein modification process GO:0031399 112 0.017
positive regulation of rna metabolic process GO:0051254 271 0.017
Yeast
regulation of sister chromatid segregation GO:0033045 28 0.017
regulation of cell development GO:0060284 215 0.016
epithelial tube morphogenesis GO:0060562 88 0.016
regulation of cell projection organization GO:0031344 92 0.016
imaginal disc derived appendage morphogenesis GO:0035114 395 0.016
regulation of establishment of protein localization GO:0070201 61 0.016
positive regulation of catabolic process GO:0009896 105 0.016
Yeast
regulation of epithelial cell proliferation GO:0050678 4 0.016
vesicle mediated transport GO:0016192 381 0.016
response to wounding GO:0009611 94 0.016
oxoacid metabolic process GO:0043436 103 0.016
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 15 0.016
organophosphate catabolic process GO:0046434 112 0.015
Human
cell recognition GO:0008037 102 0.015
positive regulation of cell migration GO:0030335 2 0.015
regulation of behavior GO:0050795 75 0.015
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.015
Yeast
negative regulation of growth GO:0045926 84 0.015
protein modification by small protein conjugation or removal GO:0070647 106 0.015
positive regulation of cell motility GO:2000147 3 0.015
chromosome separation GO:0051304 42 0.015
drinking behavior GO:0042756 2 0.015
protein transport GO:0015031 155 0.015
positive regulation of cell communication GO:0010647 250 0.015
ubiquitin homeostasis GO:0010992 1 0.014
intracellular transport GO:0046907 228 0.014
negative regulation of proteolysis GO:0045861 31 0.014
regulation of gene expression epigenetic GO:0040029 128 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
Human
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.014
endocytosis GO:0006897 310 0.014
transmembrane transport GO:0055085 139 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
molting cycle GO:0042303 56 0.013
wnt signaling pathway GO:0016055 98 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.013
regulation of meiosis GO:0040020 3 0.013
regulation of locomotion GO:0040012 42 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
protein modification by small protein conjugation GO:0032446 79 0.013
protein targeting to nucleus GO:0044744 51 0.013
cellular response to organic substance GO:0071310 132 0.013
photoreceptor cell differentiation GO:0046530 170 0.013
cellular protein modification process GO:0006464 438 0.012
non recombinational repair GO:0000726 7 0.012
regulation of nucleoside metabolic process GO:0009118 50 0.012
regulation of intracellular protein transport GO:0033157 46 0.012
positive regulation of binding GO:0051099 4 0.012
regionalization GO:0003002 416 0.012
ion transmembrane transport GO:0034220 122 0.012
response to nutrient levels GO:0031667 114 0.012
regulation of intracellular signal transduction GO:1902531 236 0.012
organonitrogen compound metabolic process GO:1901564 318 0.012
Human
negative regulation of intracellular signal transduction GO:1902532 57 0.012
response to virus GO:0009615 28 0.012
anatomical structure homeostasis GO:0060249 97 0.012
meiotic cell cycle process GO:1903046 132 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
mitotic g2 dna damage checkpoint GO:0007095 69 0.011
tube formation GO:0035148 21 0.011
regulation of nucleotide metabolic process GO:0006140 62 0.011
negative regulation of developmental process GO:0051093 201 0.011
regulation of mitotic sister chromatid separation GO:0010965 28 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
spermatogenesis GO:0007283 200 0.011
purine containing compound catabolic process GO:0072523 112 0.011
Human
reproductive system development GO:0061458 74 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
regulation of cysteine type endopeptidase activity GO:2000116 27 0.011
camera type eye morphogenesis GO:0048593 2 0.010
cellular homeostasis GO:0019725 80 0.010
macroautophagy GO:0016236 42 0.010
negative regulation of cellular component organization GO:0051129 108 0.010
single organism cellular localization GO:1902580 180 0.010
organonitrogen compound biosynthetic process GO:1901566 117 0.010
regulation of cellular response to stress GO:0080135 89 0.010
peptidyl amino acid modification GO:0018193 105 0.010
protein phosphorylation GO:0006468 169 0.010
regulation of wnt signaling pathway GO:0030111 68 0.010
negative regulation of molecular function GO:0044092 51 0.010
response to radiation GO:0009314 155 0.010
meiotic nuclear division GO:0007126 151 0.010

Rpt1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012