Drosophila melanogaster

4 known processes

Spn100A (Dmel_CG1342)

Serpin 100A

(Aliases: Dmel\CG1342,CG1342)

Spn100A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin filament based process GO:0030029 220 0.186
actin filament organization GO:0007015 126 0.109
actin cytoskeleton organization GO:0030036 206 0.098
actin filament based movement GO:0030048 26 0.071
dendrite development GO:0016358 204 0.065
regulation of embryonic cell shape GO:0016476 30 0.063
small molecule metabolic process GO:0044281 305 0.061
neurological system process GO:0050877 358 0.061
epithelial cell differentiation GO:0030855 322 0.059
sensory perception GO:0007600 196 0.057
regulation of embryonic development GO:0045995 68 0.054
organonitrogen compound metabolic process GO:1901564 318 0.053
estrogen metabolic process GO:0008210 1 0.053
dendrite morphogenesis GO:0048813 199 0.051
sensory perception of sound GO:0007605 56 0.049
sensory perception of mechanical stimulus GO:0050954 72 0.048
wing disc morphogenesis GO:0007472 344 0.047
regulation of anatomical structure morphogenesis GO:0022603 242 0.047
post embryonic appendage morphogenesis GO:0035120 385 0.046
vesicle mediated transport GO:0016192 381 0.045
cell adhesion GO:0007155 136 0.044
actin mediated cell contraction GO:0070252 21 0.040
regulation of cell shape GO:0008360 113 0.039
protein modification process GO:0036211 438 0.039
response to bacterium GO:0009617 198 0.038
appendage morphogenesis GO:0035107 397 0.037
response to organic substance GO:0010033 284 0.034
organic acid metabolic process GO:0006082 103 0.034
imaginal disc derived wing morphogenesis GO:0007476 337 0.034
carboxylic acid metabolic process GO:0019752 92 0.032
endocytosis GO:0006897 310 0.032
cellular protein modification process GO:0006464 438 0.032
negative regulation of cellular metabolic process GO:0031324 382 0.032
cellular response to chemical stimulus GO:0070887 199 0.031
appendage development GO:0048736 401 0.031
catabolic process GO:0009056 409 0.030
regulation of cell morphogenesis GO:0022604 163 0.029
cellular amino acid metabolic process GO:0006520 61 0.028
carbohydrate derivative metabolic process GO:1901135 217 0.028
defense response to bacterium GO:0042742 178 0.027
anion homeostasis GO:0055081 3 0.027
establishment of localization in cell GO:0051649 402 0.027
biological adhesion GO:0022610 138 0.027
organic substance transport GO:0071702 257 0.027
organic hydroxy compound metabolic process GO:1901615 83 0.027
response to oxygen containing compound GO:1901700 200 0.027
response to biotic stimulus GO:0009607 294 0.026
negative regulation of gene expression GO:0010629 387 0.026
body morphogenesis GO:0010171 2 0.026
organic substance catabolic process GO:1901575 308 0.025
response to lipopolysaccharide GO:0032496 4 0.025
cellular catabolic process GO:0044248 372 0.024
actin filament bundle organization GO:0061572 28 0.024
phagocytosis GO:0006909 215 0.024
regulation of multicellular organismal development GO:2000026 414 0.024
cell death GO:0008219 279 0.023
single organism intracellular transport GO:1902582 207 0.023
imaginal disc derived appendage development GO:0048737 399 0.023
positive regulation of signal transduction GO:0009967 223 0.023
response to extracellular stimulus GO:0009991 116 0.023
single organism biosynthetic process GO:0044711 206 0.023
steroid catabolic process GO:0006706 1 0.023
regionalization GO:0003002 416 0.022
oxoacid metabolic process GO:0043436 103 0.022
response to abiotic stimulus GO:0009628 341 0.022
phosphorylation GO:0016310 294 0.022
regulation of transport GO:0051049 181 0.022
imaginal disc derived appendage morphogenesis GO:0035114 395 0.021
protein transport GO:0015031 155 0.021
apical constriction GO:0003383 18 0.021
response to external biotic stimulus GO:0043207 293 0.021
cell substrate adhesion GO:0031589 10 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.020
cellular amine metabolic process GO:0044106 12 0.020
epithelial cell morphogenesis GO:0003382 25 0.020
single organism catabolic process GO:0044712 228 0.020
programmed cell death GO:0012501 257 0.019
organophosphate metabolic process GO:0019637 195 0.019
cellular ketone metabolic process GO:0042180 24 0.019
positive regulation of rna biosynthetic process GO:1902680 266 0.019
camera type eye development GO:0043010 4 0.019
amine metabolic process GO:0009308 12 0.019
proteolysis GO:0006508 192 0.019
autophagic cell death GO:0048102 83 0.019
polyol biosynthetic process GO:0046173 3 0.019
intracellular transport GO:0046907 228 0.018
regulation of molecular function GO:0065009 217 0.018
neurotransmitter metabolic process GO:0042133 2 0.018
regulation of cellular amine metabolic process GO:0033238 3 0.018
aging GO:0007568 143 0.018
protein localization GO:0008104 284 0.018
positive regulation of response to stimulus GO:0048584 323 0.018
cellular response to lipopolysaccharide GO:0071222 3 0.018
acetylcholine metabolic process GO:0008291 2 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.017
ethanolamine containing compound metabolic process GO:0042439 4 0.017
endomembrane system organization GO:0010256 119 0.017
positive regulation of cell motility GO:2000147 3 0.017
regulation of localization GO:0032879 275 0.017
regulation of protein metabolic process GO:0051246 256 0.017
intracellular signal transduction GO:0035556 300 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
forebrain development GO:0030900 2 0.017
positive regulation of biosynthetic process GO:0009891 316 0.017
response to organophosphorus GO:0046683 2 0.017
response to other organism GO:0051707 293 0.017
cellular macromolecule localization GO:0070727 220 0.017
synaptic transmission GO:0007268 288 0.017
positive regulation of cell migration GO:0030335 2 0.017
homeostatic process GO:0042592 199 0.017
xenobiotic catabolic process GO:0042178 1 0.017
regulation of catalytic activity GO:0050790 185 0.017
sensory organ morphogenesis GO:0090596 260 0.017
phosphatidylethanolamine metabolic process GO:0046337 1 0.017
triglyceride biosynthetic process GO:0019432 2 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
developmental programmed cell death GO:0010623 138 0.016
positive regulation of rna metabolic process GO:0051254 271 0.016
androgen metabolic process GO:0008209 1 0.016
regulation of response to stress GO:0080134 200 0.016
kidney development GO:0001822 3 0.016
epithelial cell development GO:0002064 274 0.016
organelle fission GO:0048285 340 0.016
death GO:0016265 284 0.015
cellular protein localization GO:0034613 160 0.015
developmental growth GO:0048589 280 0.015
connective tissue development GO:0061448 3 0.015
eye development GO:0001654 323 0.015
regulation of sequestering of triglyceride GO:0010889 3 0.015
acetate ester metabolic process GO:1900619 2 0.015
glycerolipid catabolic process GO:0046503 3 0.015
sterol homeostasis GO:0055092 4 0.015
compound eye development GO:0048749 307 0.015
actin filament bundle assembly GO:0051017 26 0.015
l amino acid import GO:0043092 2 0.015
response to endogenous stimulus GO:0009719 119 0.015
nuclear division GO:0000280 332 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
regulation of lipid transport GO:0032368 3 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.015
cellular response to ethanol GO:0071361 4 0.015
regulation of apoptotic process GO:0042981 130 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
gene silencing GO:0016458 138 0.015
defense response to other organism GO:0098542 225 0.014
posttranscriptional regulation of gene expression GO:0010608 145 0.014
negative regulation of signal transduction GO:0009968 206 0.014
cellular response to extracellular stimulus GO:0031668 64 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.014
segmentation GO:0035282 207 0.014
regulation of cell differentiation GO:0045595 302 0.014
establishment of protein localization GO:0045184 163 0.014
regulation of multi organism process GO:0043900 131 0.014
positive regulation of cell communication GO:0010647 250 0.014
acylglycerol biosynthetic process GO:0046463 2 0.014
eye morphogenesis GO:0048592 260 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
response to nutrient levels GO:0031667 114 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.014
lipid metabolic process GO:0006629 121 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
response to radiation GO:0009314 155 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
immune response activating signal transduction GO:0002757 2 0.014
macromolecule catabolic process GO:0009057 161 0.014
histolysis GO:0007559 102 0.014
alditol phosphate metabolic process GO:0052646 2 0.014
regulation of programmed cell death GO:0043067 152 0.014
organic cyclic compound catabolic process GO:1901361 168 0.014
defense response GO:0006952 300 0.014
immune response regulating signaling pathway GO:0002764 2 0.014
l glutamate import GO:0051938 1 0.014
telencephalon development GO:0021537 2 0.014
response to alcohol GO:0097305 95 0.014
positive regulation of lipid storage GO:0010884 4 0.014
cholesterol homeostasis GO:0042632 3 0.014
response to nitrogen compound GO:1901698 90 0.014
pigment metabolic process involved in pigmentation GO:0043474 33 0.014
acylglycerol catabolic process GO:0046464 3 0.014
neutral lipid biosynthetic process GO:0046460 2 0.014
secretion GO:0046903 109 0.014
response to hexose GO:0009746 3 0.014
cytoplasmic transport GO:0016482 130 0.014
response to glucose GO:0009749 2 0.014
limb development GO:0060173 1 0.014
single organism behavior GO:0044708 391 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
vitamin biosynthetic process GO:0009110 1 0.014
negative regulation of biosynthetic process GO:0009890 277 0.014
transcription from rna polymerase ii promoter GO:0006366 368 0.014
gland morphogenesis GO:0022612 145 0.014
benzene containing compound metabolic process GO:0042537 3 0.014
response to organonitrogen compound GO:0010243 75 0.014
sulfur compound metabolic process GO:0006790 59 0.014
cellular response to organic substance GO:0071310 132 0.013
regulation of epithelial cell proliferation GO:0050678 4 0.013
macromolecular complex assembly GO:0065003 256 0.013
salivary gland morphogenesis GO:0007435 145 0.013
fat soluble vitamin metabolic process GO:0006775 1 0.013
salivary gland development GO:0007431 162 0.013
meiotic cell cycle GO:0051321 171 0.013
ras protein signal transduction GO:0007265 88 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.013
imaginal disc derived wing vein specification GO:0007474 48 0.013
salivary gland cell autophagic cell death GO:0035071 83 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
determination of adult lifespan GO:0008340 137 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
heterocycle catabolic process GO:0046700 166 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
positive regulation of cellular biosynthetic process GO:0031328 316 0.013
positive regulation of gene expression GO:0010628 290 0.013
salivary gland histolysis GO:0035070 88 0.013
ribonucleoside metabolic process GO:0009119 127 0.013
hormone catabolic process GO:0042447 3 0.013
triglyceride catabolic process GO:0019433 3 0.013
regulation of nervous system development GO:0051960 248 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
spindle organization GO:0007051 253 0.013
maintenance of location GO:0051235 73 0.013
positive regulation of transcription dna templated GO:0045893 266 0.013
axon guidance GO:0007411 233 0.013
mitotic spindle organization GO:0007052 220 0.013
cellular modified amino acid metabolic process GO:0006575 45 0.013
tissue death GO:0016271 102 0.013
cell division GO:0051301 248 0.013
defense response to gram negative bacterium GO:0050829 94 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
purine containing compound metabolic process GO:0072521 155 0.013
response to monosaccharide GO:0034284 4 0.013
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
mesenchymal cell differentiation GO:0048762 1 0.013
peptidyl proline hydroxylation GO:0019511 1 0.013
male gamete generation GO:0048232 201 0.012
rna localization GO:0006403 115 0.012
regulation of intracellular signal transduction GO:1902531 236 0.012
nucleotide metabolic process GO:0009117 161 0.012
aromatic compound catabolic process GO:0019439 166 0.012
regulation of cell death GO:0010941 173 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.012
eye pigmentation GO:0048069 43 0.012
organelle assembly GO:0070925 198 0.012
mitotic nuclear division GO:0007067 213 0.012
cellular response to oxygen containing compound GO:1901701 79 0.012
cellular response to external stimulus GO:0071496 66 0.012
carbohydrate metabolic process GO:0005975 82 0.012
chaeta development GO:0022416 97 0.012
positive regulation of signaling GO:0023056 243 0.012
regulation of mitotic cell cycle GO:0007346 190 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
rna processing GO:0006396 147 0.012
cholesterol transport GO:0030301 2 0.012
chromosome segregation GO:0007059 157 0.012
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
protein processing GO:0016485 68 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
intracellular protein transport GO:0006886 104 0.012
compound eye morphogenesis GO:0001745 249 0.012
medium chain fatty acid metabolic process GO:0051791 1 0.012
positive regulation of macromolecule metabolic process GO:0010604 405 0.012
secondary metabolic process GO:0019748 75 0.012
multicellular organismal aging GO:0010259 140 0.012
hormone metabolic process GO:0042445 33 0.012
chromosome organization GO:0051276 360 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
regulation of developmental growth GO:0048638 174 0.012
gland development GO:0048732 191 0.012
cellular response to nutrient levels GO:0031669 62 0.012
phosphatidic acid metabolic process GO:0046473 1 0.011
limb morphogenesis GO:0035108 1 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.011
cuticle development GO:0042335 86 0.011
hindbrain development GO:0030902 2 0.011
purine nucleoside triphosphate metabolic process GO:0009144 119 0.011
eye photoreceptor cell differentiation GO:0001754 145 0.011
sensory perception of smell GO:0007608 80 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
killing of cells of other organism GO:0031640 1 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
regulation of synapse organization GO:0050807 110 0.011
pigment metabolic process GO:0042440 84 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
nephron development GO:0072006 3 0.011
protein complex biogenesis GO:0070271 201 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
lateral inhibition GO:0046331 206 0.011
protein transmembrane transport GO:0071806 4 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
neuron projection guidance GO:0097485 241 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
negative regulation of transcription dna templated GO:0045892 237 0.011
mesenchymal cell development GO:0014031 1 0.011
fat soluble vitamin biosynthetic process GO:0042362 1 0.011
regulation of immune system process GO:0002682 176 0.011
regulation of proteolysis GO:0030162 87 0.011
regulation of mitotic cell cycle phase transition GO:1901990 130 0.011
negative regulation of rna metabolic process GO:0051253 251 0.011
positive regulation of developmental process GO:0051094 143 0.011
negative regulation of cellular biosynthetic process GO:0031327 277 0.011
regulation of anatomical structure size GO:0090066 163 0.011
response to light stimulus GO:0009416 124 0.011
phenol containing compound metabolic process GO:0018958 57 0.011
single organism carbohydrate metabolic process GO:0044723 72 0.011
activation of innate immune response GO:0002218 4 0.011
cellular component assembly involved in morphogenesis GO:0010927 151 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
vitamin metabolic process GO:0006766 2 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
positive regulation of apoptotic signaling pathway GO:2001235 4 0.011
protein complex assembly GO:0006461 200 0.011
photoreceptor cell development GO:0042461 96 0.011
chemical homeostasis GO:0048878 92 0.011
regulation of cellular localization GO:0060341 136 0.011
innate immune response activating signal transduction GO:0002758 2 0.011
peptidyl proline modification GO:0018208 3 0.011
chemotaxis GO:0006935 249 0.011
spermatogenesis GO:0007283 200 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.010
regulation of gene silencing GO:0060968 63 0.010
positive regulation of sequestering of triglyceride GO:0010890 1 0.010
developmental pigmentation GO:0048066 68 0.010
apoptotic process GO:0006915 159 0.010
taxis GO:0042330 304 0.010
blastoderm segmentation GO:0007350 159 0.010
retina development in camera type eye GO:0060041 4 0.010
hematopoietic progenitor cell differentiation GO:0002244 1 0.010
ovarian follicle cell development GO:0030707 248 0.010
respiratory system development GO:0060541 213 0.010
single organism cellular localization GO:1902580 180 0.010
growth GO:0040007 359 0.010
ribonucleoside triphosphate metabolic process GO:0009199 119 0.010
regulation of response to external stimulus GO:0032101 115 0.010
response to paraquat GO:1901562 4 0.010
regulation of cell cycle GO:0051726 291 0.010
phosphate ion transport GO:0006817 4 0.010
positive regulation of transport GO:0051050 92 0.010
chromatin organization GO:0006325 207 0.010
regulation of synapse assembly GO:0051963 94 0.010
regulation of defense response GO:0031347 102 0.010
gene silencing by rna GO:0031047 57 0.010
regulation of response to biotic stimulus GO:0002831 63 0.010
negative regulation of developmental process GO:0051093 201 0.010
immune system process GO:0002376 347 0.010
purine nucleoside metabolic process GO:0042278 127 0.010
cellular nitrogen compound catabolic process GO:0044270 165 0.010
regulation of gene expression epigenetic GO:0040029 128 0.010
pigmentation GO:0043473 75 0.010
glycosyl compound metabolic process GO:1901657 127 0.010
cellular lipid metabolic process GO:0044255 83 0.010
organophosphate catabolic process GO:0046434 112 0.010

Spn100A disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.055
nervous system disease DOID:863 0 0.019
disease of metabolism DOID:0014667 0 0.018
inherited metabolic disorder DOID:655 0 0.018
cardiovascular system disease DOID:1287 0 0.017
diabetes mellitus DOID:9351 0 0.016
type 2 diabetes mellitus DOID:9352 0 0.016
carbohydrate metabolism disease DOID:0050013 0 0.016
glucose metabolism disease DOID:4194 0 0.016
acquired metabolic disease DOID:0060158 0 0.016
sensory system disease DOID:0050155 0 0.014
musculoskeletal system disease DOID:17 0 0.014
urinary system disease DOID:18 0 0.013
familial hyperlipidemia DOID:1168 0 0.011
lipid metabolism disorder DOID:3146 0 0.011
familial combined hyperlipidemia DOID:13809 0 0.011
hair disease DOID:421 0 0.011
integumentary system disease DOID:16 0 0.011
hypotrichosis DOID:4535 0 0.011
disease of cellular proliferation DOID:14566 0 0.010
eye and adnexa disease DOID:1492 0 0.010