Drosophila melanogaster

47 known processes

Sp1 (Dmel_CG1343)

CG1343 gene product from transcript CG1343-RB

(Aliases: Dmel\CG1343,CG1343,SP1,dSp1,D-Sp1,sp1,D.Sp1,D-Sp8)

Sp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
appendage morphogenesis GO:0035107 397 0.843
appendage development GO:0048736 401 0.793
imaginal disc derived appendage morphogenesis GO:0035114 395 0.717
wing disc morphogenesis GO:0007472 344 0.541
post embryonic appendage morphogenesis GO:0035120 385 0.517
imaginal disc derived wing morphogenesis GO:0007476 337 0.505
epithelial cell differentiation GO:0030855 322 0.381
imaginal disc derived appendage development GO:0048737 399 0.368
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.363
regionalization GO:0003002 416 0.343
Mouse
locomotory behavior GO:0007626 176 0.262
segmentation GO:0035282 207 0.253
transcription from rna polymerase ii promoter GO:0006366 368 0.211
positive regulation of gene expression GO:0010628 290 0.211
positive regulation of transcription dna templated GO:0045893 266 0.198
positive regulation of macromolecule metabolic process GO:0010604 405 0.197
compound eye morphogenesis GO:0001745 249 0.168
neurological system process GO:0050877 358 0.147
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.144
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.143
eye morphogenesis GO:0048592 260 0.142
negative regulation of gene expression GO:0010629 387 0.134
circadian behavior GO:0048512 76 0.133
regulation of imaginal disc derived wing size GO:0044719 20 0.130
regulation of multicellular organismal development GO:2000026 414 0.122
developmental growth GO:0048589 280 0.112
regulation of anatomical structure size GO:0090066 163 0.110
negative regulation of transcription dna templated GO:0045892 237 0.108
embryonic morphogenesis GO:0048598 206 0.105
Zebrafish Mouse
defense response GO:0006952 300 0.101
positive regulation of rna biosynthetic process GO:1902680 266 0.101
compound eye development GO:0048749 307 0.099
eye development GO:0001654 323 0.096
positive regulation of biosynthetic process GO:0009891 316 0.095
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.095
digestive tract morphogenesis GO:0048546 127 0.095
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.093
muscle structure development GO:0061061 224 0.093
axonogenesis GO:0007409 290 0.090
axon development GO:0061564 297 0.085
single organism behavior GO:0044708 391 0.084
locomotor rhythm GO:0045475 56 0.084
taxis GO:0042330 304 0.082
negative regulation of cellular metabolic process GO:0031324 382 0.081
columnar cuboidal epithelial cell development GO:0002066 249 0.078
regulation of cell proliferation GO:0042127 163 0.078
neuron projection guidance GO:0097485 241 0.078
response to organic substance GO:0010033 284 0.077
Zebrafish
positive regulation of rna metabolic process GO:0051254 271 0.077
renal system development GO:0072001 72 0.075
regulation of localization GO:0032879 275 0.072
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.072
cell proliferation GO:0008283 299 0.072
kidney development GO:0001822 3 0.067
gland development GO:0048732 191 0.067
epithelial cell development GO:0002064 274 0.067
positive regulation of nucleic acid templated transcription GO:1903508 266 0.064
connective tissue development GO:0061448 3 0.063
developmental programmed cell death GO:0010623 138 0.063
positive regulation of developmental process GO:0051094 143 0.060
defense response to other organism GO:0098542 225 0.060
localization of cell GO:0051674 257 0.059
dorsal ventral pattern formation GO:0009953 133 0.058
Mouse
cell migration GO:0016477 238 0.056
extracellular structure organization GO:0043062 46 0.056
germ cell migration GO:0008354 43 0.055
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.054
response to alcohol GO:0097305 95 0.053
photoreceptor cell differentiation GO:0046530 170 0.053
rhythmic process GO:0048511 106 0.052
rhythmic behavior GO:0007622 76 0.052
response to other organism GO:0051707 293 0.050
positive regulation of cellular biosynthetic process GO:0031328 316 0.049
enzyme linked receptor protein signaling pathway GO:0007167 179 0.049
Zebrafish
circadian rhythm GO:0007623 105 0.049
cell motility GO:0048870 251 0.048
response to biotic stimulus GO:0009607 294 0.048
sensory organ morphogenesis GO:0090596 260 0.047
response to external biotic stimulus GO:0043207 293 0.047
response to oxygen containing compound GO:1901700 200 0.047
ovarian follicle cell development GO:0030707 248 0.047
anterior posterior pattern specification GO:0009952 136 0.046
body morphogenesis GO:0010171 2 0.045
leg disc development GO:0035218 92 0.045
detection of chemical stimulus involved in sensory perception of smell GO:0050911 50 0.044
kidney morphogenesis GO:0060993 3 0.044
macromolecular complex assembly GO:0065003 256 0.043
regulation of developmental growth GO:0048638 174 0.043
hair cell differentiation GO:0035315 47 0.042
adult behavior GO:0030534 137 0.042
tissue morphogenesis GO:0048729 297 0.042
salivary gland morphogenesis GO:0007435 145 0.041
olfactory behavior GO:0042048 97 0.041
protein complex assembly GO:0006461 200 0.041
chemosensory behavior GO:0007635 106 0.040
actin cytoskeleton organization GO:0030036 206 0.040
defense response to fungus GO:0050832 48 0.040
carbohydrate derivative metabolic process GO:1901135 217 0.040
gastrulation with mouth forming first GO:0001703 36 0.040
negative regulation of cell differentiation GO:0045596 143 0.038
protein complex biogenesis GO:0070271 201 0.037
chemotaxis GO:0006935 249 0.037
organic substance transport GO:0071702 257 0.037
response to nitrogen compound GO:1901698 90 0.037
negative regulation of multicellular organismal process GO:0051241 142 0.037
tissue migration GO:0090130 155 0.037
dendrite morphogenesis GO:0048813 199 0.036
anterior posterior axis specification embryo GO:0008595 103 0.036
nephron tubule development GO:0072080 3 0.036
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.036
embryonic hindgut morphogenesis GO:0048619 48 0.035
sex differentiation GO:0007548 81 0.035
blastoderm segmentation GO:0007350 159 0.035
regulation of programmed cell death GO:0043067 152 0.034
morphogenesis of an epithelium GO:0002009 276 0.034
leg disc morphogenesis GO:0007478 80 0.034
organonitrogen compound metabolic process GO:1901564 318 0.034
regulation of growth GO:0040008 233 0.034
endocytosis GO:0006897 310 0.034
negative regulation of response to stimulus GO:0048585 258 0.034
salivary gland development GO:0007431 162 0.034
detection of stimulus involved in sensory perception GO:0050906 92 0.034
camera type eye development GO:0043010 4 0.034
regulation of cellular component biogenesis GO:0044087 201 0.033
protein modification by small protein conjugation GO:0032446 79 0.033
imaginal disc derived wing vein specification GO:0007474 48 0.033
death GO:0016265 284 0.033
compound eye photoreceptor cell differentiation GO:0001751 140 0.033
imaginal disc derived leg morphogenesis GO:0007480 80 0.033
torso signaling pathway GO:0008293 21 0.033
dendrite development GO:0016358 204 0.032
programmed cell death GO:0012501 257 0.032
negative regulation of cellular biosynthetic process GO:0031327 277 0.032
reproductive structure development GO:0048608 74 0.032
regulation of intracellular signal transduction GO:1902531 236 0.032
epidermal growth factor receptor signaling pathway GO:0007173 58 0.032
tripartite regional subdivision GO:0007351 103 0.030
developmental growth involved in morphogenesis GO:0060560 65 0.030
chromatin organization GO:0006325 207 0.030
regulation of catabolic process GO:0009894 170 0.030
tube morphogenesis GO:0035239 191 0.030
reproductive system development GO:0061458 74 0.030
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.029
Zebrafish
wing disc pattern formation GO:0035222 66 0.029
organ growth GO:0035265 56 0.029
growth GO:0040007 359 0.028
head development GO:0060322 135 0.028
vesicle mediated transport GO:0016192 381 0.028
cellular response to oxygen containing compound GO:1901701 79 0.028
mesoderm development GO:0007498 78 0.028
negative regulation of rna metabolic process GO:0051253 251 0.028
determination of imaginal disc primordium GO:0007445 11 0.027
eggshell formation GO:0030703 105 0.027
chromosome organization GO:0051276 360 0.027
regulation of anatomical structure morphogenesis GO:0022603 242 0.027
protein modification process GO:0036211 438 0.027
phosphorylation GO:0016310 294 0.026
muscle organ development GO:0007517 127 0.026
positive regulation of response to stimulus GO:0048584 323 0.026
Zebrafish
single organism intracellular transport GO:1902582 207 0.026
segment specification GO:0007379 33 0.026
positive regulation of cellular component organization GO:0051130 156 0.025
positive regulation of multicellular organismal process GO:0051240 143 0.025
regulation of multi organism process GO:0043900 131 0.025
imaginal disc pattern formation GO:0007447 91 0.025
cell death GO:0008219 279 0.024
cell division GO:0051301 248 0.024
regulation of cell development GO:0060284 215 0.024
positive regulation of catabolic process GO:0009896 105 0.024
kidney epithelium development GO:0072073 3 0.024
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.024
negative regulation of biosynthetic process GO:0009890 277 0.024
intracellular transport GO:0046907 228 0.024
regulation of protein metabolic process GO:0051246 256 0.023
immune response GO:0006955 246 0.023
proteoglycan biosynthetic process GO:0030166 10 0.023
response to abiotic stimulus GO:0009628 341 0.023
positive regulation of phosphorus metabolic process GO:0010562 139 0.023
defense response to bacterium GO:0042742 178 0.023
regulation of cell cycle GO:0051726 291 0.023
eye photoreceptor cell differentiation GO:0001754 145 0.023
catabolic process GO:0009056 409 0.023
anterior posterior axis specification GO:0009948 109 0.023
carbohydrate derivative biosynthetic process GO:1901137 85 0.023
erbb signaling pathway GO:0038127 58 0.023
regulation of molecular function GO:0065009 217 0.023
immune system process GO:0002376 347 0.023
retina development in camera type eye GO:0060041 4 0.022
negative regulation of signal transduction GO:0009968 206 0.022
tube development GO:0035295 244 0.022
regulation of immune system process GO:0002682 176 0.022
phagocytosis GO:0006909 215 0.022
chorion containing eggshell formation GO:0007304 105 0.022
response to organic cyclic compound GO:0014070 89 0.022
positive regulation of signal transduction GO:0009967 223 0.022
Zebrafish
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.022
negative regulation of erbb signaling pathway GO:1901185 29 0.022
digestive system development GO:0055123 149 0.022
intracellular protein transport GO:0006886 104 0.022
establishment of localization in cell GO:0051649 402 0.022
renal tubule morphogenesis GO:0061333 44 0.022
ventral furrow formation GO:0007370 17 0.022
actin filament based process GO:0030029 220 0.022
digestive tract development GO:0048565 149 0.021
stem cell proliferation GO:0072089 88 0.021
nephron tubule morphogenesis GO:0072078 3 0.021
regulation of nervous system development GO:0051960 248 0.021
protein heterooligomerization GO:0051291 4 0.021
regulation of mitotic cell cycle GO:0007346 190 0.021
brain development GO:0007420 120 0.021
response to organophosphorus GO:0046683 2 0.021
cellular response to mechanical stimulus GO:0071260 2 0.021
cognition GO:0050890 141 0.021
antennal development GO:0007469 25 0.020
protein transport GO:0015031 155 0.020
forebrain development GO:0030900 2 0.020
response to endogenous stimulus GO:0009719 119 0.020
Zebrafish
imaginal disc growth GO:0007446 37 0.020
wnt signaling pathway GO:0016055 98 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.020
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.020
positive regulation of signaling GO:0023056 243 0.020
Zebrafish
cell fate specification GO:0001708 71 0.020
secretion GO:0046903 109 0.020
neuron maturation GO:0042551 31 0.019
neuron recognition GO:0008038 101 0.019
cellular catabolic process GO:0044248 372 0.019
embryonic axis specification GO:0000578 107 0.019
intracellular signal transduction GO:0035556 300 0.019
tissue death GO:0016271 102 0.019
establishment of protein localization GO:0045184 163 0.019
respiratory system development GO:0060541 213 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.019
negative regulation of cell communication GO:0010648 223 0.019
stem cell differentiation GO:0048863 117 0.019
skin development GO:0043588 65 0.019
negative regulation of cell death GO:0060548 81 0.018
apoptotic process GO:0006915 159 0.018
response to ecdysone GO:0035075 34 0.018
embryonic pattern specification GO:0009880 174 0.018
homeostatic process GO:0042592 199 0.018
regulation of cellular component size GO:0032535 98 0.018
small molecule metabolic process GO:0044281 305 0.018
nephron development GO:0072006 3 0.018
purine containing compound catabolic process GO:0072523 112 0.018
carbohydrate derivative catabolic process GO:1901136 118 0.018
mesenchymal cell differentiation GO:0048762 1 0.018
sensory perception GO:0007600 196 0.018
developmental maturation GO:0021700 172 0.018
nuclear division GO:0000280 332 0.018
hindgut development GO:0061525 58 0.018
compound eye photoreceptor fate commitment GO:0001752 36 0.017
activation of innate immune response GO:0002218 4 0.017
cell maturation GO:0048469 144 0.017
neuroblast differentiation GO:0014016 29 0.017
regulation of cell differentiation GO:0045595 302 0.017
gene silencing GO:0016458 138 0.017
nephron epithelium development GO:0072009 3 0.017
regulation of epithelial cell proliferation GO:0050678 4 0.017
ameboidal type cell migration GO:0001667 151 0.017
humoral immune response GO:0006959 117 0.017
gastrulation GO:0007369 70 0.017
cell recognition GO:0008037 102 0.017
histolysis GO:0007559 102 0.017
purine nucleoside metabolic process GO:0042278 127 0.017
protein localization GO:0008104 284 0.017
regulation of organ morphogenesis GO:2000027 78 0.016
gland morphogenesis GO:0022612 145 0.016
immune response activating signal transduction GO:0002757 2 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
gastrulation involving germ band extension GO:0010004 36 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
negative regulation of developmental process GO:0051093 201 0.016
response to sterol GO:0036314 34 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.016
reproductive behavior GO:0019098 122 0.016
organ formation GO:0048645 39 0.016
learning or memory GO:0007611 141 0.016
photoreceptor cell fate commitment GO:0046552 41 0.016
exocrine system development GO:0035272 162 0.015
regulation of cell death GO:0010941 173 0.015
salivary gland histolysis GO:0035070 88 0.015
cellular amino acid metabolic process GO:0006520 61 0.015
response to organonitrogen compound GO:0010243 75 0.015
regulation of gene silencing GO:0060968 63 0.015
cranial nerve development GO:0021545 1 0.015
cellular response to dna damage stimulus GO:0006974 223 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.015
response to bacterium GO:0009617 198 0.015
immune response regulating signaling pathway GO:0002764 2 0.015
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.015
regulation of erbb signaling pathway GO:1901184 42 0.015
sensory organ precursor cell fate determination GO:0016360 19 0.015
embryonic organ development GO:0048568 50 0.015
peripheral nervous system development GO:0007422 52 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
regulation of phosphorus metabolic process GO:0051174 210 0.015
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.015
mitotic cytokinesis GO:0000281 50 0.015
hippo signaling GO:0035329 20 0.015
sensory organ boundary specification GO:0008052 22 0.015
nephron morphogenesis GO:0072028 3 0.015
ribonucleoside triphosphate metabolic process GO:0009199 119 0.015
cellular response to chemical stimulus GO:0070887 199 0.015
Zebrafish
salivary gland cell autophagic cell death GO:0035071 83 0.015
cellular macromolecule localization GO:0070727 220 0.015
glycoprotein metabolic process GO:0009100 41 0.014
urogenital system development GO:0001655 72 0.014
positive regulation of cellular component biogenesis GO:0044089 80 0.014
formation of organ boundary GO:0010160 30 0.014
negative regulation of programmed cell death GO:0043069 72 0.014
nucleoside metabolic process GO:0009116 127 0.014
cellular protein localization GO:0034613 160 0.014
response to lipopolysaccharide GO:0032496 4 0.014
central nervous system development GO:0007417 201 0.014
aging GO:0007568 143 0.014
regulation of protein localization GO:0032880 76 0.014
endodermal cell differentiation GO:0035987 3 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
meiosis i GO:0007127 59 0.014
mapk cascade GO:0000165 107 0.014
cell cell signaling involved in cell fate commitment GO:0045168 210 0.014
renal tubule development GO:0061326 64 0.014
negative regulation of nucleic acid templated transcription GO:1903507 240 0.014
regulation of organ growth GO:0046620 42 0.014
decapentaplegic signaling pathway GO:0008101 19 0.013
chromosome segregation GO:0007059 157 0.013
regulation of cellular localization GO:0060341 136 0.013
germ line stem cell maintenance GO:0030718 50 0.013
organophosphate metabolic process GO:0019637 195 0.013
cell fate determination involved in pattern specification GO:0060582 19 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.013
germarium derived egg chamber formation GO:0007293 101 0.013
ribonucleoside catabolic process GO:0042454 112 0.013
chromatin modification GO:0016568 147 0.013
sensory perception of smell GO:0007608 80 0.013
sulfur compound metabolic process GO:0006790 59 0.013
cellular response to organonitrogen compound GO:0071417 36 0.013
cellular response to organic substance GO:0071310 132 0.013
Zebrafish
histone modification GO:0016570 106 0.013
positive regulation of cell migration GO:0030335 2 0.013
protein phosphorylation GO:0006468 169 0.013
establishment or maintenance of cell polarity GO:0007163 167 0.013
regulation of apoptotic process GO:0042981 130 0.013
pigmentation GO:0043473 75 0.013
stress activated mapk cascade GO:0051403 52 0.013
malpighian tubule morphogenesis GO:0007443 44 0.013
l glutamate import GO:0051938 1 0.013
nephron epithelium morphogenesis GO:0072088 3 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
regulation of organelle organization GO:0033043 196 0.013
organelle fission GO:0048285 340 0.013
antimicrobial humoral response GO:0019730 99 0.012
malpighian tubule development GO:0072002 64 0.012
oxoacid metabolic process GO:0043436 103 0.012
muscle tissue development GO:0060537 30 0.012
segment polarity determination GO:0007367 25 0.012
organic substance catabolic process GO:1901575 308 0.012
r8 cell fate commitment GO:0007460 6 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
response to peptide GO:1901652 29 0.012
wing disc dorsal ventral pattern formation GO:0048190 47 0.012
positive regulation of multi organism process GO:0043902 40 0.012
eye antennal disc development GO:0035214 60 0.012
heart development GO:0007507 82 0.012
epidermis development GO:0008544 65 0.012
axis specification GO:0009798 167 0.012
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.012
chaeta morphogenesis GO:0008407 42 0.012
single organism biosynthetic process GO:0044711 206 0.012
positive regulation of neuron differentiation GO:0045666 26 0.012
multi organism reproductive behavior GO:0044705 121 0.012
autophagic cell death GO:0048102 83 0.012
gonad development GO:0008406 50 0.012
protein modification by small protein conjugation or removal GO:0070647 106 0.012
meiotic nuclear division GO:0007126 151 0.012
epithelial cell migration GO:0010631 148 0.012
cellular response to peptide hormone stimulus GO:0071375 28 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
eye photoreceptor cell fate commitment GO:0042706 37 0.012
regulation of synapse assembly GO:0051963 94 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.011
organic acid metabolic process GO:0006082 103 0.011
secretion by cell GO:0032940 101 0.011
regulation of compound eye cone cell fate specification GO:0042682 4 0.011
regulation of decapentaplegic signaling pathway GO:0090097 8 0.011
regulation of cell division GO:0051302 72 0.011
regulation of notch signaling pathway GO:0008593 100 0.011
phototaxis GO:0042331 21 0.011
carboxylic acid metabolic process GO:0019752 92 0.011
regulation of neurogenesis GO:0050767 158 0.011
extracellular matrix organization GO:0030198 32 0.011
nucleotide catabolic process GO:0009166 109 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
cell cycle phase transition GO:0044770 140 0.011
glycoprotein biosynthetic process GO:0009101 41 0.011
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.011
nucleoside triphosphate metabolic process GO:0009141 120 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.011
regulation of bmp signaling pathway GO:0030510 23 0.011
neuron fate determination GO:0048664 1 0.011
pattern recognition receptor signaling pathway GO:0002221 2 0.011
response to ketone GO:1901654 34 0.011
regulation of multicellular organism growth GO:0040014 40 0.011
purine nucleotide catabolic process GO:0006195 109 0.011
ovarian follicle cell migration GO:0007297 121 0.011
apoptotic process involved in morphogenesis GO:0060561 3 0.010
establishment of ommatidial planar polarity GO:0042067 49 0.010
posttranscriptional gene silencing by rna GO:0035194 45 0.010
epithelium migration GO:0090132 148 0.010
camera type eye morphogenesis GO:0048593 2 0.010
morphogenesis of embryonic epithelium GO:0016331 94 0.010
regulation of cell fate specification GO:0042659 27 0.010
innate immune response activating signal transduction GO:0002758 2 0.010
negative regulation of cell proliferation GO:0008285 69 0.010
ribonucleoside triphosphate catabolic process GO:0009203 108 0.010
spinal cord development GO:0021510 1 0.010
positive regulation of mapk cascade GO:0043410 63 0.010
organophosphate catabolic process GO:0046434 112 0.010

Sp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
disease of metabolism DOID:0014667 0 0.018
carbohydrate metabolism disease DOID:0050013 0 0.018
glucose metabolism disease DOID:4194 0 0.018
acquired metabolic disease DOID:0060158 0 0.018
diabetes mellitus DOID:9351 0 0.015
inherited metabolic disorder DOID:655 0 0.015
nervous system disease DOID:863 0 0.015
disease of cellular proliferation DOID:14566 0 0.014
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012
sensory system disease DOID:0050155 0 0.010