Drosophila melanogaster

248 known processes

Pi3K92E (Dmel_CG4141)

CG4141 gene product from transcript CG4141-RB

(Aliases: p120,dPI3K,PI3'K,PI3K-dp110,Pi3K92D,PI3K-92E/Dp110,Dmp110,dP110,Dmel\CG4141,PI(3)K,PI3K-Dp110,Pi3Kp110,PI-3-K,CG4141,PI3K-92D,rea,p110,PI3K,Dp110,PI[[3]]K,Dp110/PI3K,PI3K92E,PI-3 kinase,type-1 PI3K,anon-92Ed,PI3k,Pi3K,dp110)

Pi3K92E biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
growth GO:0040007 359 1.000
regulation of growth GO:0040008 233 1.000
regulation of cell growth GO:0001558 43 1.000
Zebrafish
macroautophagy GO:0016236 42 1.000
cell growth GO:0016049 108 1.000
Zebrafish
regulation of dendrite morphogenesis GO:0048814 28 1.000
cellular catabolic process GO:0044248 372 1.000
autophagic vacuole assembly GO:0000045 2 1.000
positive regulation of cell growth GO:0030307 19 1.000
intracellular signal transduction GO:0035556 300 0.999
positive regulation of developmental growth GO:0048639 62 0.999
response to oxygen containing compound GO:1901700 200 0.999
autophagy GO:0006914 108 0.999
regulation of protein metabolic process GO:0051246 256 0.998
regulation of cell development GO:0060284 215 0.998
developmental growth GO:0048589 280 0.998
negative regulation of cell communication GO:0010648 223 0.998
regulation of cellular component biogenesis GO:0044087 201 0.998
negative regulation of signaling GO:0023057 219 0.998
negative regulation of signal transduction GO:0009968 206 0.997
dendrite morphogenesis GO:0048813 199 0.997
cellular response to chemical stimulus GO:0070887 199 0.997
purine nucleotide catabolic process GO:0006195 109 0.996
small molecule metabolic process GO:0044281 305 0.996
catabolic process GO:0009056 409 0.996
regulation of catabolic process GO:0009894 170 0.996
purine nucleoside metabolic process GO:0042278 127 0.996
response to organic substance GO:0010033 284 0.995
regulation of intracellular signal transduction GO:1902531 236 0.995
organic substance catabolic process GO:1901575 308 0.995
regulation of apoptotic process GO:0042981 130 0.995
regulation of cellular catabolic process GO:0031329 157 0.995
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.994
positive regulation of hydrolase activity GO:0051345 78 0.994
regulation of developmental growth GO:0048638 174 0.994
cellular response to peptide hormone stimulus GO:0071375 28 0.993
regulation of cell size GO:0008361 63 0.993
ribose phosphate metabolic process GO:0019693 145 0.993
synaptic growth at neuromuscular junction GO:0051124 119 0.992
purine ribonucleotide catabolic process GO:0009154 109 0.992
single organism catabolic process GO:0044712 228 0.992
nucleoside triphosphate catabolic process GO:0009143 108 0.991
regulation of cell differentiation GO:0045595 302 0.990
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.990
response to other organism GO:0051707 293 0.989
protein modification by small protein conjugation or removal GO:0070647 106 0.989
nucleotide metabolic process GO:0009117 161 0.989
determination of adult lifespan GO:0008340 137 0.989
Worm
dendrite development GO:0016358 204 0.988
regulation of cell morphogenesis GO:0022604 163 0.987
Zebrafish
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.986
positive regulation of growth GO:0045927 75 0.985
ribonucleotide metabolic process GO:0009259 145 0.984
regulation of autophagy GO:0010506 62 0.984
organophosphate metabolic process GO:0019637 195 0.984
regulation of nurse cell apoptotic process GO:0045477 9 0.984
regulation of nucleotide catabolic process GO:0030811 48 0.983
cell division GO:0051301 248 0.983
Mouse
regulation of macroautophagy GO:0016241 15 0.983
cell motility GO:0048870 251 0.982
ovarian follicle cell development GO:0030707 248 0.982
regulation of localization GO:0032879 275 0.982
ribonucleoside catabolic process GO:0042454 112 0.982
actin filament based process GO:0030029 220 0.982
Fly
nucleoside phosphate catabolic process GO:1901292 110 0.981
purine nucleoside triphosphate catabolic process GO:0009146 108 0.980
purine ribonucleoside catabolic process GO:0046130 112 0.980
guanosine containing compound catabolic process GO:1901069 74 0.980
purine containing compound catabolic process GO:0072523 112 0.980
ribonucleoside metabolic process GO:0009119 127 0.978
regulation of dendrite development GO:0050773 37 0.977
cell type specific apoptotic process GO:0097285 38 0.976
tube development GO:0035295 244 0.976
regulation of nucleoside metabolic process GO:0009118 50 0.976
neuromuscular junction development GO:0007528 149 0.975
programmed cell death GO:0012501 257 0.975
regulation of anatomical structure size GO:0090066 163 0.972
synapse organization GO:0050808 196 0.972
regulation of organelle organization GO:0033043 196 0.970
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.970
response to peptide GO:1901652 29 0.970
regulation of protein localization GO:0032880 76 0.969
regulation of cell cycle GO:0051726 291 0.969
regulation of phosphorylation GO:0042325 147 0.968
multicellular organism growth GO:0035264 46 0.967
negative regulation of response to stimulus GO:0048585 258 0.966
nucleobase containing small molecule metabolic process GO:0055086 174 0.966
cellular response to peptide GO:1901653 28 0.966
regulation of rho protein signal transduction GO:0035023 20 0.965
germ line stem cell division GO:0042078 25 0.964
cellular response to oxygen containing compound GO:1901701 79 0.963
regulation of gtpase activity GO:0043087 44 0.963
purine nucleoside catabolic process GO:0006152 112 0.962
regulation of nervous system development GO:0051960 248 0.961
immune system process GO:0002376 347 0.959
Mouse
response to insulin GO:0032868 29 0.959
digestive system development GO:0055123 149 0.959
ribonucleoside triphosphate metabolic process GO:0009199 119 0.959
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.958
establishment of localization in cell GO:0051649 402 0.958
lipid metabolic process GO:0006629 121 0.957
positive regulation of multicellular organismal process GO:0051240 143 0.957
nucleobase containing compound catabolic process GO:0034655 165 0.956
phosphorylation GO:0016310 294 0.956
purine nucleotide metabolic process GO:0006163 146 0.955
regulation of cellular component size GO:0032535 98 0.954
positive regulation of rna metabolic process GO:0051254 271 0.951
single organism intracellular transport GO:1902582 207 0.950
positive regulation of catabolic process GO:0009896 105 0.948
regulation of small gtpase mediated signal transduction GO:0051056 93 0.948
nucleotide catabolic process GO:0009166 109 0.948
positive regulation of cellular biosynthetic process GO:0031328 316 0.946
regulation of hydrolase activity GO:0051336 97 0.945
ribonucleoside triphosphate catabolic process GO:0009203 108 0.944
guanosine containing compound metabolic process GO:1901068 74 0.944
organelle fission GO:0048285 340 0.943
cellular protein modification process GO:0006464 438 0.943
negative regulation of cellular metabolic process GO:0031324 382 0.942
aging GO:0007568 143 0.941
Worm
nucleoside catabolic process GO:0009164 112 0.940
regulation of multi organism process GO:0043900 131 0.940
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.940
regulation of protein kinase activity GO:0045859 51 0.939
cell death GO:0008219 279 0.939
response to nitrogen compound GO:1901698 90 0.939
vesicle mediated transport GO:0016192 381 0.938
Fly
death GO:0016265 284 0.938
localization of cell GO:0051674 257 0.935
purine containing compound metabolic process GO:0072521 155 0.934
regulation of immune system process GO:0002682 176 0.933
positive regulation of developmental process GO:0051094 143 0.933
chemotaxis GO:0006935 249 0.932
Worm
negative regulation of growth GO:0045926 84 0.931
ribonucleotide catabolic process GO:0009261 109 0.930
epithelial cell development GO:0002064 274 0.930
apoptotic process GO:0006915 159 0.929
ras protein signal transduction GO:0007265 88 0.928
synapse assembly GO:0007416 143 0.927
cell migration GO:0016477 238 0.927
regulation of phosphate metabolic process GO:0019220 210 0.927
positive regulation of cellular catabolic process GO:0031331 95 0.926
carbohydrate derivative catabolic process GO:1901136 118 0.925
organophosphate catabolic process GO:0046434 112 0.924
nucleoside triphosphate metabolic process GO:0009141 120 0.923
protein modification process GO:0036211 438 0.921
defense response GO:0006952 300 0.920
protein phosphorylation GO:0006468 169 0.919
regulation of programmed cell death GO:0043067 152 0.919
transcription from rna polymerase ii promoter GO:0006366 368 0.918
single organism behavior GO:0044708 391 0.916
ameboidal type cell migration GO:0001667 151 0.915
cellular response to insulin stimulus GO:0032869 28 0.913
regulation of protein transport GO:0051223 57 0.913
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.911
negative regulation of autophagy GO:0010507 16 0.910
positive regulation of proteolysis GO:0045862 52 0.910
organ growth GO:0035265 56 0.908
intracellular transport GO:0046907 228 0.906
positive regulation of phosphorus metabolic process GO:0010562 139 0.905
nucleoside metabolic process GO:0009116 127 0.905
response to ethanol GO:0045471 59 0.903
purine ribonucleotide metabolic process GO:0009150 145 0.899
circadian rhythm GO:0007623 105 0.899
glycosyl compound catabolic process GO:1901658 112 0.896
regulation of gtp catabolic process GO:0033124 44 0.895
response to starvation GO:0042594 97 0.894
positive regulation of multicellular organism growth GO:0040018 21 0.892
response to organonitrogen compound GO:0010243 75 0.890
morphogenesis of an epithelium GO:0002009 276 0.890
muscle structure development GO:0061061 224 0.888
negative regulation of multicellular organismal process GO:0051241 142 0.884
multicellular organismal aging GO:0010259 140 0.884
Worm
cellular response to hormone stimulus GO:0032870 44 0.882
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.881
regulation of multicellular organismal development GO:2000026 414 0.880
regulation of phosphorus metabolic process GO:0051174 210 0.879
tor signaling GO:0031929 32 0.878
stress activated mapk cascade GO:0051403 52 0.878
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.876
regulation of phosphatidylinositol 3 kinase activity GO:0043551 2 0.875
nucleoside phosphate metabolic process GO:0006753 162 0.874
positive regulation of axonogenesis GO:0050772 2 0.874
carbohydrate derivative metabolic process GO:1901135 217 0.870
cellular response to endogenous stimulus GO:0071495 80 0.870
embryo development ending in birth or egg hatching GO:0009792 152 0.870
positive regulation of cellular response to insulin stimulus GO:1900078 4 0.865
negative regulation of intracellular signal transduction GO:1902532 57 0.861
rhythmic process GO:0048511 106 0.857
purine nucleoside triphosphate metabolic process GO:0009144 119 0.852
stress activated protein kinase signaling cascade GO:0031098 55 0.847
nuclear division GO:0000280 332 0.847
regulation of mapk cascade GO:0043408 92 0.843
positive regulation of response to stimulus GO:0048584 323 0.842
endocytosis GO:0006897 310 0.840
Fly
cognition GO:0050890 141 0.838
Worm
regulation of tor signaling GO:0032006 21 0.836
activation of protein kinase activity GO:0032147 12 0.834
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.833
defense response to bacterium GO:0042742 178 0.833
eye morphogenesis GO:0048592 260 0.824
regulation of molecular function GO:0065009 217 0.822
positive regulation of tor signaling GO:0032008 13 0.818
regulation of axonogenesis GO:0050770 32 0.817
Zebrafish
protein catabolic process GO:0030163 101 0.816
cell substrate adhesion GO:0031589 10 0.814
Mouse
regulation of ras gtpase activity GO:0032318 38 0.814
positive regulation of phosphate metabolic process GO:0045937 139 0.813
cellular macromolecule localization GO:0070727 220 0.812
positive regulation of protein phosphorylation GO:0001934 34 0.812
regulation of cysteine type endopeptidase activity GO:2000116 27 0.811
regulation of rho gtpase activity GO:0032319 20 0.811
regulation of multicellular organism growth GO:0040014 40 0.810
positive regulation of intracellular signal transduction GO:1902533 116 0.810
regulation of cell death GO:0010941 173 0.807
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.806
regulation of cell projection organization GO:0031344 92 0.803
regulation of protein serine threonine kinase activity GO:0071900 25 0.802
cellular response to nitrogen compound GO:1901699 51 0.802
regionalization GO:0003002 416 0.802
taxis GO:0042330 304 0.799
Worm
regulation of response to external stimulus GO:0032101 115 0.799
Worm
response to peptide hormone GO:0043434 29 0.796
macromolecule catabolic process GO:0009057 161 0.793
positive regulation of phosphorylation GO:0042327 87 0.791
negative regulation of phosphorus metabolic process GO:0010563 45 0.791
male gamete generation GO:0048232 201 0.790
blastoderm segmentation GO:0007350 159 0.787
response to external biotic stimulus GO:0043207 293 0.786
imaginal disc derived appendage development GO:0048737 399 0.785
oocyte development GO:0048599 124 0.785
signal transduction by phosphorylation GO:0023014 107 0.784
regulation of establishment of protein localization GO:0070201 61 0.783
response to heat GO:0009408 63 0.780
segmentation GO:0035282 207 0.780
small gtpase mediated signal transduction GO:0007264 88 0.779
positive regulation of biosynthetic process GO:0009891 316 0.774
regulation of response to nutrient levels GO:0032107 18 0.773
positive regulation of rna biosynthetic process GO:1902680 266 0.772
regulation of protein phosphorylation GO:0001932 64 0.769
aromatic compound catabolic process GO:0019439 166 0.769
positive regulation of signaling GO:0023056 243 0.767
digestive tract development GO:0048565 149 0.766
mushroom body development GO:0016319 70 0.765
single organism membrane organization GO:0044802 93 0.764
axon guidance GO:0007411 233 0.762
negative regulation of molecular function GO:0044092 51 0.760
organonitrogen compound catabolic process GO:1901565 128 0.755
rho protein signal transduction GO:0007266 14 0.754
negative regulation of developmental process GO:0051093 201 0.752
positive regulation of cell differentiation GO:0045597 64 0.750
regulation of catalytic activity GO:0050790 185 0.748
regulation of rac protein signal transduction GO:0035020 3 0.747
positive regulation of macromolecule metabolic process GO:0010604 405 0.746
positive regulation of rho gtpase activity GO:0032321 19 0.746
digestive tract morphogenesis GO:0048546 127 0.744
epithelium migration GO:0090132 148 0.743
positive regulation of nucleic acid templated transcription GO:1903508 266 0.741
stem cell division GO:0017145 69 0.739
response to extracellular stimulus GO:0009991 116 0.739
cellular response to organic substance GO:0071310 132 0.738
purine ribonucleoside metabolic process GO:0046128 127 0.734
regulation of epithelial cell proliferation GO:0050678 4 0.734
negative regulation of cell proliferation GO:0008285 69 0.733
gtp catabolic process GO:0006184 72 0.733
gtp metabolic process GO:0046039 72 0.732
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 1 0.730
appendage morphogenesis GO:0035107 397 0.726
regulation of organ growth GO:0046620 42 0.726
regulation of map kinase activity GO:0043405 17 0.721
larval midgut histolysis GO:0035069 22 0.717
positive regulation of programmed cell death GO:0043068 62 0.716
protein modification by small protein conjugation GO:0032446 79 0.709
actin cytoskeleton organization GO:0030036 206 0.708
Fly
muscle cell differentiation GO:0042692 103 0.706
negative regulation of phosphate metabolic process GO:0045936 45 0.704
regulation of stress activated mapk cascade GO:0032872 41 0.701
developmental cell growth GO:0048588 52 0.701
Zebrafish
organonitrogen compound metabolic process GO:1901564 318 0.691
positive regulation of gene expression GO:0010628 290 0.690
actin filament organization GO:0007015 126 0.690
positive regulation of cell death GO:0010942 69 0.685
negative regulation of neuromuscular synaptic transmission GO:1900074 7 0.685
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.684
regulation of purine nucleotide catabolic process GO:0033121 48 0.682
regulation of proteolysis GO:0030162 87 0.669
regulation of jnk cascade GO:0046328 40 0.667
heterocycle catabolic process GO:0046700 166 0.666
cellular macromolecular complex assembly GO:0034622 153 0.665
regulation of cell migration GO:0030334 22 0.661
developmental programmed cell death GO:0010623 138 0.660
negative regulation of wnt signaling pathway GO:0030178 28 0.660
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.659
proteolysis GO:0006508 192 0.658
tube morphogenesis GO:0035239 191 0.657
entry into diapause GO:0055115 1 0.654
organic cyclic compound catabolic process GO:1901361 168 0.650
axon extension GO:0048675 32 0.645
epithelial cell differentiation GO:0030855 322 0.645
negative regulation of apoptotic process GO:0043066 63 0.645
negative regulation of neurogenesis GO:0050768 53 0.644
peptidyl tyrosine modification GO:0018212 24 0.644
epithelial cell migration GO:0010631 148 0.641
apoptotic process involved in development GO:1902742 20 0.640
larval development GO:0002164 104 0.636
sex differentiation GO:0007548 81 0.635
response to bacterium GO:0009617 198 0.632
negative regulation of nervous system development GO:0051961 92 0.632
response to abiotic stimulus GO:0009628 341 0.631
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.630
border follicle cell migration GO:0007298 113 0.628
negative regulation of transferase activity GO:0051348 18 0.626
regulation of synapse assembly GO:0051963 94 0.625
spermatogenesis GO:0007283 200 0.625
positive regulation of protein metabolic process GO:0051247 128 0.625
positive regulation of cellular component organization GO:0051130 156 0.625
regulation of cytoskeleton organization GO:0051493 89 0.624
regulation of response to stress GO:0080134 200 0.623
ribonucleoside monophosphate metabolic process GO:0009161 51 0.622
response to uv GO:0009411 24 0.618
response to radiation GO:0009314 155 0.618
regulation of cellular amino acid metabolic process GO:0006521 0 0.617
positive regulation of autophagy GO:0010508 21 0.617
cellular response to nutrient levels GO:0031669 62 0.613
negative regulation of developmental growth GO:0048640 64 0.610
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.608
extrinsic apoptotic signaling pathway GO:0097191 1 0.607
regulation of neuron projection development GO:0010975 69 0.607
positive regulation of cell migration GO:0030335 2 0.601
olfactory learning GO:0008355 56 0.600
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.599
stem cell development GO:0048864 79 0.597
urogenital system development GO:0001655 72 0.596
positive regulation of apoptotic process GO:0043065 47 0.593
positive regulation of signal transduction GO:0009967 223 0.593
cell maturation GO:0048469 144 0.592
mapk cascade GO:0000165 107 0.591
regulation of synapse organization GO:0050807 110 0.586
negative regulation of cell development GO:0010721 62 0.584
olfactory behavior GO:0042048 97 0.584
negative regulation of synapse assembly GO:0051964 39 0.584
dna metabolic process GO:0006259 227 0.582
imaginal disc derived wing morphogenesis GO:0007476 337 0.579
positive regulation of nucleotide metabolic process GO:0045981 55 0.569
regulation of cellular protein metabolic process GO:0032268 243 0.564
appendage development GO:0048736 401 0.564
axon regeneration GO:0031103 8 0.560
embryonic morphogenesis GO:0048598 206 0.557
cellular nitrogen compound catabolic process GO:0044270 165 0.555
cellular response to dna damage stimulus GO:0006974 223 0.550
Fly
wnt signaling pathway GO:0016055 98 0.548
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.548
muscle organ development GO:0007517 127 0.547
developmental growth involved in morphogenesis GO:0060560 65 0.545
Zebrafish
reproductive structure development GO:0048608 74 0.545
actin cytoskeleton reorganization GO:0031532 22 0.539
actin filament bundle organization GO:0061572 28 0.539
regulation of neurogenesis GO:0050767 158 0.538
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.535
regulation of locomotion GO:0040012 42 0.533
Worm
cellular response to starvation GO:0009267 61 0.533
positive regulation of lipid metabolic process GO:0045834 4 0.533
compound eye development GO:0048749 307 0.526
stress fiber assembly GO:0043149 6 0.521
carboxylic acid metabolic process GO:0019752 92 0.519
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.516
gland development GO:0048732 191 0.514
cellular amine metabolic process GO:0044106 12 0.509
positive regulation of molecular function GO:0044093 136 0.506
negative regulation of catalytic activity GO:0043086 42 0.505
regulation of lipid kinase activity GO:0043550 2 0.503
negative regulation of kinase activity GO:0033673 16 0.502
negative regulation of cellular component organization GO:0051129 108 0.501
neuron maturation GO:0042551 31 0.500
positive regulation of protein kinase activity GO:0045860 25 0.497
larval feeding behavior GO:0030536 15 0.489
regulation of purine nucleotide metabolic process GO:1900542 62 0.486
development of primary sexual characteristics GO:0045137 50 0.483
tissue death GO:0016271 102 0.482
filopodium assembly GO:0046847 33 0.481
regulation of cellular response to stress GO:0080135 89 0.480
brain development GO:0007420 120 0.478
circadian behavior GO:0048512 76 0.475
regulation of cell proliferation GO:0042127 163 0.474
regulation of cellular response to insulin stimulus GO:1900076 17 0.473
regulation of nucleotide metabolic process GO:0006140 62 0.473
protein import into nucleus GO:0006606 51 0.470
regulation of cellular localization GO:0060341 136 0.466
positive regulation of catalytic activity GO:0043085 118 0.464
positive regulation of cell communication GO:0010647 250 0.463
regulation of insulin receptor signaling pathway GO:0046626 17 0.459
cell fate specification GO:0001708 71 0.459
cellular response to organonitrogen compound GO:0071417 36 0.457
connective tissue development GO:0061448 3 0.454
chemosensory behavior GO:0007635 106 0.452
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.452
dormancy process GO:0022611 2 0.452
regulation of ras protein signal transduction GO:0046578 93 0.451
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.450
tissue migration GO:0090130 155 0.449
positive regulation of protein modification process GO:0031401 58 0.446
response to hypoxia GO:0001666 53 0.444
response to hormone GO:0009725 45 0.440
regulation of cellular ketone metabolic process GO:0010565 3 0.438
cellular ketone metabolic process GO:0042180 24 0.436
regulation of axon extension GO:0030516 8 0.433
hemopoiesis GO:0030097 46 0.431
positive regulation of transcription dna templated GO:0045893 266 0.427
locomotory behavior GO:0007626 176 0.424
single organism biosynthetic process GO:0044711 206 0.423
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.421
regulation of anatomical structure morphogenesis GO:0022603 242 0.419
Zebrafish
endosomal transport GO:0016197 44 0.415
protein complex assembly GO:0006461 200 0.412
cellular amino acid metabolic process GO:0006520 61 0.409
response to axon injury GO:0048678 12 0.403
positive regulation of nitric oxide biosynthetic process GO:0045429 1 0.402
compound eye morphogenesis GO:0001745 249 0.401
insulin receptor signaling pathway GO:0008286 25 0.396
endomembrane system organization GO:0010256 119 0.393
positive regulation of cell proliferation GO:0008284 47 0.392
protein localization to plasma membrane GO:0072659 13 0.390
negative regulation of cellular protein metabolic process GO:0032269 85 0.390
regulation of nitric oxide biosynthetic process GO:0045428 1 0.388
negative regulation of programmed cell death GO:0043069 72 0.380
cell proliferation GO:0008283 299 0.378
phosphatidylinositol mediated signaling GO:0048015 4 0.376
oocyte microtubule cytoskeleton organization GO:0016325 35 0.369
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.367
lipid modification GO:0030258 24 0.367
defense response to other organism GO:0098542 225 0.366
regulation of endocytosis GO:0030100 37 0.366
regulation of cell division GO:0051302 72 0.365
positive regulation of gtpase activity GO:0043547 43 0.365
negative regulation of mapk cascade GO:0043409 23 0.364
maintenance of location GO:0051235 73 0.363
negative regulation of phosphorylation GO:0042326 35 0.361
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.360
photoreceptor cell differentiation GO:0046530 170 0.358
stem cell differentiation GO:0048863 117 0.352
neuron projection extension GO:1990138 32 0.352
negative regulation of protein modification process GO:0031400 29 0.352
post embryonic appendage morphogenesis GO:0035120 385 0.351
regulation of cell cell adhesion GO:0022407 21 0.350
positive regulation of organelle organization GO:0010638 65 0.345
phagocytosis GO:0006909 215 0.345
Fly
inositol lipid mediated signaling GO:0048017 4 0.343
cell cycle g1 s phase transition GO:0044843 31 0.340
regulation of kinase activity GO:0043549 53 0.338
positive regulation of protein catabolic process GO:0045732 34 0.333
jnk cascade GO:0007254 50 0.327
membrane organization GO:0061024 112 0.326
negative regulation of protein metabolic process GO:0051248 85 0.322
regulation of protein modification process GO:0031399 112 0.321
positive regulation of cellular amine metabolic process GO:0033240 0 0.321
regulation of neuron differentiation GO:0045664 103 0.320
rhythmic behavior GO:0007622 76 0.319
regeneration GO:0031099 16 0.317
response to lipid GO:0033993 38 0.314
regulation of transferase activity GO:0051338 58 0.313
tissue morphogenesis GO:0048729 297 0.311
regulation of actin filament length GO:0030832 27 0.310
cytoplasmic transport GO:0016482 130 0.309
regulation of axon regeneration GO:0048679 4 0.308
columnar cuboidal epithelial cell development GO:0002066 249 0.304
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.302
eggshell formation GO:0030703 105 0.300
negative regulation of response to external stimulus GO:0032102 22 0.299
protein kinase b signaling GO:0043491 1 0.298
neurological system process GO:0050877 358 0.296
Worm
organic acid metabolic process GO:0006082 103 0.295
interspecies interaction between organisms GO:0044419 16 0.294
positive regulation of cell motility GO:2000147 3 0.292
protein localization to nucleus GO:0034504 55 0.284
ovarian follicle cell migration GO:0007297 121 0.284
symbiosis encompassing mutualism through parasitism GO:0044403 16 0.283
positive regulation of lipid catabolic process GO:0050996 1 0.283
mesenchymal cell differentiation GO:0048762 1 0.281
negative regulation of cell differentiation GO:0045596 143 0.280
oocyte differentiation GO:0009994 145 0.278
embryonic pattern specification GO:0009880 174 0.276
hematopoietic or lymphoid organ development GO:0048534 57 0.273
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.271
nuclear import GO:0051170 51 0.271
r7 cell differentiation GO:0045466 43 0.270
negative regulation of insulin receptor signaling pathway GO:0046627 11 0.269
positive regulation of mapk cascade GO:0043410 63 0.268
response to endogenous stimulus GO:0009719 119 0.265
glycosyl compound metabolic process GO:1901657 127 0.265
response to biotic stimulus GO:0009607 294 0.263
positive regulation of response to external stimulus GO:0032103 44 0.263
learning or memory GO:0007611 141 0.262
Worm
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 6 0.262
chorion containing eggshell formation GO:0007304 105 0.262
positive regulation of nucleotide catabolic process GO:0030813 46 0.260
cell competition in a multicellular organism GO:0035212 10 0.260
organelle assembly GO:0070925 198 0.260
establishment of organelle localization GO:0051656 122 0.257
peptidyl threonine phosphorylation GO:0018107 2 0.257

Pi3K92E disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.363