Drosophila melanogaster

140 known processes

Ada2b (Dmel_CG9638)

CG9638 gene product from transcript CG9638-RA

(Aliases: BcDNA:LD24527,ada2b,CG9638,dAda2S,ADA2b,dAda2b,Ada2B,dADA2b,Dmel\CG9638,Ada2S,dAda2B)

Ada2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell cycle GO:0051726 291 0.855
positive regulation of biosynthetic process GO:0009891 316 0.765
intracellular signal transduction GO:0035556 300 0.732
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.721
cellular protein modification process GO:0006464 438 0.663
transcription from rna polymerase ii promoter GO:0006366 368 0.646
Yeast
cellular catabolic process GO:0044248 372 0.595
single organism biosynthetic process GO:0044711 206 0.573
establishment of localization in cell GO:0051649 402 0.572
nuclear division GO:0000280 332 0.562
meiotic nuclear division GO:0007126 151 0.560
small molecule metabolic process GO:0044281 305 0.551
chromatin modification GO:0016568 147 0.550
positive regulation of macromolecule metabolic process GO:0010604 405 0.501
programmed cell death GO:0012501 257 0.499
death GO:0016265 284 0.498
meiotic cell cycle GO:0051321 171 0.488
cell proliferation GO:0008283 299 0.486
catabolic process GO:0009056 409 0.475
chromosome organization GO:0051276 360 0.462
cell division GO:0051301 248 0.461
positive regulation of cellular biosynthetic process GO:0031328 316 0.460
regionalization GO:0003002 416 0.418
organic substance catabolic process GO:1901575 308 0.409
protein modification by small protein removal GO:0070646 28 0.366
positive regulation of cell communication GO:0010647 250 0.361
cell death GO:0008219 279 0.344
positive regulation of gene expression GO:0010628 290 0.336
tube development GO:0035295 244 0.321
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.317
embryonic pattern specification GO:0009880 174 0.316
negative regulation of cell cycle GO:0045786 116 0.310
organonitrogen compound metabolic process GO:1901564 318 0.305
protein modification process GO:0036211 438 0.298
mitotic dna integrity checkpoint GO:0044774 75 0.297
response to lipopolysaccharide GO:0032496 4 0.288
regulation of response to stress GO:0080134 200 0.286
protein deubiquitination GO:0016579 17 0.284
posttranscriptional regulation of gene expression GO:0010608 145 0.268
regulation of protein metabolic process GO:0051246 256 0.263
positive regulation of rna biosynthetic process GO:1902680 266 0.259
open tracheal system development GO:0007424 204 0.255
negative regulation of mitotic cell cycle GO:0045930 109 0.251
dna damage checkpoint GO:0000077 78 0.251
regulation of cellular protein metabolic process GO:0032268 243 0.244
negative regulation of signaling GO:0023057 219 0.243
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.235
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.234
regulation of phosphorylation GO:0042325 147 0.224
cellular response to chemical stimulus GO:0070887 199 0.220
regulation of meiosis GO:0040020 3 0.213
embryo development ending in birth or egg hatching GO:0009792 152 0.206
protein phosphorylation GO:0006468 169 0.204
dna integrity checkpoint GO:0031570 81 0.188
positive regulation of response to stimulus GO:0048584 323 0.179
regulation of catalytic activity GO:0050790 185 0.173
oocyte differentiation GO:0009994 145 0.163
embryonic morphogenesis GO:0048598 206 0.158
regulation of protein phosphorylation GO:0001932 64 0.155
carbohydrate derivative catabolic process GO:1901136 118 0.151
histone modification GO:0016570 106 0.151
regulation of molecular function GO:0065009 217 0.150
phosphorylation GO:0016310 294 0.149
regulation of phosphorus metabolic process GO:0051174 210 0.149
dna templated transcriptional preinitiation complex assembly GO:0070897 20 0.149
response to organic substance GO:0010033 284 0.148
cellular response to hormone stimulus GO:0032870 44 0.143
negative regulation of cell cycle phase transition GO:1901988 103 0.141
regulation of localization GO:0032879 275 0.140
imaginal disc pattern formation GO:0007447 91 0.139
regulation of cell proliferation GO:0042127 163 0.137
positive regulation of rna metabolic process GO:0051254 271 0.136
cellular response to dna damage stimulus GO:0006974 223 0.136
positive regulation of phosphate metabolic process GO:0045937 139 0.136
mitotic g2 m transition checkpoint GO:0044818 70 0.135
regulation of cell cycle process GO:0010564 181 0.135
negative regulation of biosynthetic process GO:0009890 277 0.134
Yeast
cellular homeostasis GO:0019725 80 0.129
muscle structure development GO:0061061 224 0.129
regulation of mitotic cell cycle phase transition GO:1901990 130 0.126
positive regulation of catalytic activity GO:0043085 118 0.126
peptidyl lysine acetylation GO:0018394 39 0.123
organelle fission GO:0048285 340 0.121
g2 dna damage checkpoint GO:0031572 69 0.118
positive regulation of nucleic acid templated transcription GO:1903508 266 0.114
protein acetylation GO:0006473 39 0.110
organophosphate metabolic process GO:0019637 195 0.109
positive regulation of molecular function GO:0044093 136 0.108
regulation of transport GO:0051049 181 0.106
innate immune response GO:0045087 144 0.106
positive regulation of signaling GO:0023056 243 0.099
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 20 0.098
regulation of cell cycle phase transition GO:1901987 130 0.096
mitotic cell cycle checkpoint GO:0007093 88 0.096
protein acylation GO:0043543 42 0.093
anatomical structure homeostasis GO:0060249 97 0.089
regulation of transferase activity GO:0051338 58 0.088
positive regulation of protein metabolic process GO:0051247 128 0.086
regulation of mitotic cell cycle GO:0007346 190 0.083
regulation of multicellular organismal development GO:2000026 414 0.081
chromatin organization GO:0006325 207 0.081
purine containing compound metabolic process GO:0072521 155 0.079
renal system development GO:0072001 72 0.079
cell migration GO:0016477 238 0.077
cellular response to organic substance GO:0071310 132 0.075
cell motility GO:0048870 251 0.074
positive regulation of cellular protein metabolic process GO:0032270 118 0.072
homeostatic process GO:0042592 199 0.072
positive regulation of phosphorus metabolic process GO:0010562 139 0.072
oocyte development GO:0048599 124 0.070
response to bacterium GO:0009617 198 0.068
internal protein amino acid acetylation GO:0006475 38 0.068
regulation of nervous system development GO:0051960 248 0.066
dorsal ventral pattern formation GO:0009953 133 0.066
intracellular mrna localization GO:0008298 66 0.064
regulation of apoptotic process GO:0042981 130 0.064
regulation of protein modification process GO:0031399 112 0.064
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.062
Yeast
regulation of cell division GO:0051302 72 0.061
positive regulation of immune response GO:0050778 63 0.061
digestive tract development GO:0048565 149 0.060
positive regulation of transcription dna templated GO:0045893 266 0.059
developmental programmed cell death GO:0010623 138 0.059
histone h3 k9 acetylation GO:0043970 3 0.059
positive regulation of protein modification process GO:0031401 58 0.059
enzyme linked receptor protein signaling pathway GO:0007167 179 0.058
gonad development GO:0008406 50 0.057
negative regulation of response to stimulus GO:0048585 258 0.055
guanosine containing compound catabolic process GO:1901069 74 0.055
negative regulation of cellular biosynthetic process GO:0031327 277 0.052
Yeast
cellular amine metabolic process GO:0044106 12 0.051
histone h3 acetylation GO:0043966 11 0.051
nucleotide catabolic process GO:0009166 109 0.051
positive regulation of signal transduction GO:0009967 223 0.050
vesicle mediated transport GO:0016192 381 0.050
development of primary sexual characteristics GO:0045137 50 0.050
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.049
Yeast
regulation of cellular response to stress GO:0080135 89 0.049
morphogenesis of an epithelium GO:0002009 276 0.049
apoptotic process GO:0006915 159 0.049
glial cell migration GO:0008347 31 0.049
growth GO:0040007 359 0.047
localization of cell GO:0051674 257 0.047
regulation of kinase activity GO:0043549 53 0.046
respiratory system development GO:0060541 213 0.045
nucleoside phosphate metabolic process GO:0006753 162 0.045
urogenital system development GO:0001655 72 0.045
proteolysis GO:0006508 192 0.044
carbohydrate derivative metabolic process GO:1901135 217 0.044
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.044
regulation of cellular localization GO:0060341 136 0.043
protein modification by small protein conjugation or removal GO:0070647 106 0.043
regulation of cell death GO:0010941 173 0.043
gland morphogenesis GO:0022612 145 0.043
cellular macromolecule catabolic process GO:0044265 136 0.042
aromatic compound catabolic process GO:0019439 166 0.042
regulation of intracellular signal transduction GO:1902531 236 0.041
salivary gland cell autophagic cell death GO:0035071 83 0.041
pole plasm oskar mrna localization GO:0045451 46 0.041
purine nucleoside metabolic process GO:0042278 127 0.041
regulation of cellular catabolic process GO:0031329 157 0.041
reproductive system development GO:0061458 74 0.040
response to biotic stimulus GO:0009607 294 0.040
ribose phosphate metabolic process GO:0019693 145 0.039
response to hormone GO:0009725 45 0.039
digestive system development GO:0055123 149 0.039
cell cycle phase transition GO:0044770 140 0.038
endocytosis GO:0006897 310 0.038
purine ribonucleotide metabolic process GO:0009150 145 0.038
regulation of organelle organization GO:0033043 196 0.037
mitotic dna damage checkpoint GO:0044773 74 0.037
gliogenesis GO:0042063 80 0.037
regulation of cellular amino acid metabolic process GO:0006521 0 0.036
response to lipid GO:0033993 38 0.036
response to peptide GO:1901652 29 0.036
peptidyl lysine modification GO:0018205 57 0.036
mitotic g2 dna damage checkpoint GO:0007095 69 0.036
regulation of mapk cascade GO:0043408 92 0.035
regulation of cellular ketone metabolic process GO:0010565 3 0.035
response to oxygen containing compound GO:1901700 200 0.035
organic hydroxy compound metabolic process GO:1901615 83 0.035
cellular macromolecule localization GO:0070727 220 0.034
regulation of phosphate metabolic process GO:0019220 210 0.034
positive regulation of phosphorylation GO:0042327 87 0.034
organic cyclic compound catabolic process GO:1901361 168 0.034
tissue morphogenesis GO:0048729 297 0.034
membrane organization GO:0061024 112 0.034
cellular response to biotic stimulus GO:0071216 4 0.033
organic substance transport GO:0071702 257 0.033
camera type eye development GO:0043010 4 0.033
heterocycle catabolic process GO:0046700 166 0.033
response to peptide hormone GO:0043434 29 0.033
purine nucleotide metabolic process GO:0006163 146 0.032
regulation of protein kinase activity GO:0045859 51 0.032
nucleobase containing compound catabolic process GO:0034655 165 0.031
positive regulation of catabolic process GO:0009896 105 0.031
embryonic axis specification GO:0000578 107 0.031
positive regulation of nervous system development GO:0051962 69 0.031
salivary gland morphogenesis GO:0007435 145 0.031
stem cell maintenance GO:0019827 67 0.031
reproductive structure development GO:0048608 74 0.030
dna replication GO:0006260 48 0.030
regulation of notch signaling pathway GO:0008593 100 0.030
phagocytosis GO:0006909 215 0.030
regulation of proteolysis GO:0030162 87 0.030
cellular nitrogen compound catabolic process GO:0044270 165 0.030
oocyte construction GO:0007308 112 0.030
tube morphogenesis GO:0035239 191 0.030
regulation of hydrolase activity GO:0051336 97 0.029
defense response to gram negative bacterium GO:0050829 94 0.029
regulation of response to external stimulus GO:0032101 115 0.029
protein localization GO:0008104 284 0.029
covalent chromatin modification GO:0016569 106 0.029
cellular protein catabolic process GO:0044257 83 0.029
positive regulation of transport GO:0051050 92 0.029
response to organic cyclic compound GO:0014070 89 0.029
dna biosynthetic process GO:0071897 24 0.029
negative regulation of cellular metabolic process GO:0031324 382 0.028
Yeast
regulation of vesicle mediated transport GO:0060627 59 0.028
regulation of programmed cell death GO:0043067 152 0.028
signal transduction by phosphorylation GO:0023014 107 0.028
carboxylic acid metabolic process GO:0019752 92 0.028
nucleoside catabolic process GO:0009164 112 0.028
digestive tract morphogenesis GO:0048546 127 0.027
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.027
Yeast
extrinsic apoptotic signaling pathway GO:0097191 1 0.027
regulation of small gtpase mediated signal transduction GO:0051056 93 0.027
intracellular transport GO:0046907 228 0.026
developmental maturation GO:0021700 172 0.026
purine ribonucleoside catabolic process GO:0046130 112 0.026
blastoderm segmentation GO:0007350 159 0.026
glycosyl compound catabolic process GO:1901658 112 0.026
cell maturation GO:0048469 144 0.025
tissue death GO:0016271 102 0.025
organophosphate catabolic process GO:0046434 112 0.025
double strand break repair GO:0006302 26 0.025
histolysis GO:0007559 102 0.025
immune response GO:0006955 246 0.025
negative regulation of apoptotic process GO:0043066 63 0.024
negative regulation of cell communication GO:0010648 223 0.024
modification dependent protein catabolic process GO:0019941 78 0.024
apoptotic signaling pathway GO:0097190 27 0.024
protein catabolic process GO:0030163 101 0.024
amine metabolic process GO:0009308 12 0.024
negative regulation of cell cycle process GO:0010948 109 0.024
purine ribonucleotide catabolic process GO:0009154 109 0.024
small gtpase mediated signal transduction GO:0007264 88 0.024
organonitrogen compound catabolic process GO:1901565 128 0.023
dendrite morphogenesis GO:0048813 199 0.023
alternative mrna splicing via spliceosome GO:0000380 60 0.023
positive regulation of cellular component organization GO:0051130 156 0.023
single organism cellular localization GO:1902580 180 0.023
central nervous system development GO:0007417 201 0.022
wing disc pattern formation GO:0035222 66 0.022
ribonucleotide catabolic process GO:0009261 109 0.022
salivary gland histolysis GO:0035070 88 0.022
negative regulation of protein metabolic process GO:0051248 85 0.022
protein transport GO:0015031 155 0.022
small molecule biosynthetic process GO:0044283 37 0.022
positive regulation of cell proliferation GO:0008284 47 0.022
negative regulation of cell death GO:0060548 81 0.022
tripartite regional subdivision GO:0007351 103 0.022
single organism catabolic process GO:0044712 228 0.021
organic hydroxy compound biosynthetic process GO:1901617 21 0.021
proteasomal protein catabolic process GO:0010498 59 0.021
regulation of meiotic cell cycle GO:0051445 9 0.021
single organism intracellular transport GO:1902582 207 0.021
telencephalon development GO:0021537 2 0.021
sex differentiation GO:0007548 81 0.021
oocyte axis specification GO:0007309 108 0.021
regulation of catabolic process GO:0009894 170 0.020
organic acid metabolic process GO:0006082 103 0.020
purine nucleotide catabolic process GO:0006195 109 0.020
oocyte dorsal ventral axis specification GO:0007310 34 0.020
regulation of cellular amine metabolic process GO:0033238 3 0.020
cellular response to lipid GO:0071396 20 0.020
organelle localization GO:0051640 148 0.020
response to other organism GO:0051707 293 0.020
nitrogen compound transport GO:0071705 85 0.019
response to endogenous stimulus GO:0009719 119 0.019
larval development GO:0002164 104 0.019
neurological system process GO:0050877 358 0.019
gtp catabolic process GO:0006184 72 0.019
neural precursor cell proliferation GO:0061351 75 0.018
regulation of nucleotide metabolic process GO:0006140 62 0.018
regulation of gene silencing GO:0060968 63 0.018
ribonucleoside catabolic process GO:0042454 112 0.017
wound healing GO:0042060 75 0.017
defense response GO:0006952 300 0.017
maintenance of protein location GO:0045185 28 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.017
cellular response to organonitrogen compound GO:0071417 36 0.017
monosaccharide metabolic process GO:0005996 9 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
cellular ketone metabolic process GO:0042180 24 0.017
nucleobase containing small molecule metabolic process GO:0055086 174 0.016
secretion by cell GO:0032940 101 0.016
macromolecule catabolic process GO:0009057 161 0.016
establishment of protein localization GO:0045184 163 0.016
regulation of anatomical structure size GO:0090066 163 0.016
purine ribonucleoside metabolic process GO:0046128 127 0.016
regulation of intracellular protein transport GO:0033157 46 0.016
nucleoside phosphate catabolic process GO:1901292 110 0.016
axis specification GO:0009798 167 0.016
muscle organ development GO:0007517 127 0.015
nucleotide metabolic process GO:0009117 161 0.015
response to abiotic stimulus GO:0009628 341 0.015
lateral inhibition GO:0046331 206 0.015
taxis GO:0042330 304 0.015
autophagic cell death GO:0048102 83 0.015
positive regulation of nucleotide metabolic process GO:0045981 55 0.015
negative regulation of gene expression GO:0010629 387 0.015
Yeast
ribonucleotide metabolic process GO:0009259 145 0.015
salivary gland development GO:0007431 162 0.015
positive regulation of cellular catabolic process GO:0031331 95 0.015
notch signaling pathway GO:0007219 120 0.015
hindgut development GO:0061525 58 0.015
response to molecule of bacterial origin GO:0002237 7 0.014
response to nutrient levels GO:0031667 114 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
positive regulation of kinase activity GO:0033674 25 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
positive regulation of transferase activity GO:0051347 26 0.014
dorsal ventral axis specification GO:0009950 66 0.014
ubiquitin dependent protein catabolic process GO:0006511 78 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
carbohydrate metabolic process GO:0005975 82 0.014
ras protein signal transduction GO:0007265 88 0.014
secretion GO:0046903 109 0.014
cellular response to oxygen containing compound GO:1901701 79 0.014
response to nitrogen compound GO:1901698 90 0.014
purine containing compound catabolic process GO:0072523 112 0.014
cellular response to peptide GO:1901653 28 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.014
cell growth GO:0016049 108 0.014
mapk cascade GO:0000165 107 0.013
defense response to bacterium GO:0042742 178 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.013
cell aging GO:0007569 2 0.013
cellular response to peptide hormone stimulus GO:0071375 28 0.013
negative regulation of growth GO:0045926 84 0.013
positive regulation of peptidase activity GO:0010952 29 0.013
cellular amino acid metabolic process GO:0006520 61 0.013
regulation of nuclear division GO:0051783 58 0.013
negative regulation of developmental process GO:0051093 201 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.013
Yeast
cell fate specification GO:0001708 71 0.013
cellular response to nitrogen compound GO:1901699 51 0.013
positive regulation of neurogenesis GO:0050769 41 0.013
regulation of protein localization GO:0032880 76 0.013
exocrine system development GO:0035272 162 0.013
cellular response to organic cyclic compound GO:0071407 32 0.012
response to external biotic stimulus GO:0043207 293 0.012
cytoplasmic transport GO:0016482 130 0.012
nuclear transport GO:0051169 72 0.012
chemical homeostasis GO:0048878 92 0.012
multi organism reproductive behavior GO:0044705 121 0.012
meiotic cell cycle process GO:1903046 132 0.012
positive regulation of secretion by cell GO:1903532 20 0.012
body morphogenesis GO:0010171 2 0.012
rna localization GO:0006403 115 0.012
ribonucleoside triphosphate catabolic process GO:0009203 108 0.012
defense response to other organism GO:0098542 225 0.012
histone h4 k12 acetylation GO:0043983 2 0.012
cellular response to external stimulus GO:0071496 66 0.012
cell cycle checkpoint GO:0000075 95 0.012
gland development GO:0048732 191 0.012
lipid metabolic process GO:0006629 121 0.012
regulation of intracellular transport GO:0032386 64 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
positive regulation of nucleoside metabolic process GO:0045979 47 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
Yeast
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.011
response to organonitrogen compound GO:0010243 75 0.011
regulation of nucleocytoplasmic transport GO:0046822 35 0.011
formation of a compartment boundary GO:0060288 4 0.011
cellular chemical homeostasis GO:0055082 40 0.011
cellular response to extracellular stimulus GO:0031668 64 0.011
negative regulation of protein modification process GO:0031400 29 0.011
retina development in camera type eye GO:0060041 4 0.011
positive regulation of exocytosis GO:0045921 4 0.011
regulation of cell differentiation GO:0045595 302 0.011
positive regulation of cell development GO:0010720 61 0.011
negative regulation of phosphorylation GO:0042326 35 0.011
modification dependent macromolecule catabolic process GO:0043632 79 0.011
developmental growth GO:0048589 280 0.010
positive regulation of protein phosphorylation GO:0001934 34 0.010
regulation of establishment of protein localization GO:0070201 61 0.010
regulation of wnt signaling pathway GO:0030111 68 0.010
regulation of secretion GO:0051046 44 0.010
glycosyl compound metabolic process GO:1901657 127 0.010

Ada2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.060
nervous system disease DOID:863 0 0.021
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
thoracic cancer DOID:5093 0 0.014
organ system cancer DOID:0050686 0 0.014