Drosophila melanogaster

0 known processes

TwdlM (Dmel_CG5468)

TweedleM

(Aliases: CG5468,Dmel\CG5468)

TwdlM biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cuticle development GO:0042335 86 0.092
Fly
chitin based cuticle development GO:0040003 49 0.080
Fly
body morphogenesis GO:0010171 2 0.077
response to organic substance GO:0010033 284 0.062
response to lipopolysaccharide GO:0032496 4 0.052
response to oxygen containing compound GO:1901700 200 0.050
wing disc morphogenesis GO:0007472 344 0.039
cellular response to chemical stimulus GO:0070887 199 0.038
kidney epithelium development GO:0072073 3 0.038
imaginal disc derived appendage development GO:0048737 399 0.037
cellular response to light stimulus GO:0071482 37 0.037
response to abiotic stimulus GO:0009628 341 0.035
kidney development GO:0001822 3 0.035
nephron epithelium development GO:0072009 3 0.033
intracellular signal transduction GO:0035556 300 0.033
endocytosis GO:0006897 310 0.033
imaginal disc derived wing morphogenesis GO:0007476 337 0.033
negative regulation of signaling GO:0023057 219 0.033
vesicle mediated transport GO:0016192 381 0.033
organic substance transport GO:0071702 257 0.033
cellular response to abiotic stimulus GO:0071214 58 0.032
death GO:0016265 284 0.031
epithelial cell differentiation GO:0030855 322 0.031
cellular response to organic substance GO:0071310 132 0.031
defense response GO:0006952 300 0.030
cellular response to radiation GO:0071478 52 0.030
response to bacterium GO:0009617 198 0.028
negative regulation of response to stimulus GO:0048585 258 0.028
negative regulation of signal transduction GO:0009968 206 0.028
outflow tract morphogenesis GO:0003151 4 0.026
camera type eye development GO:0043010 4 0.025
nephron development GO:0072006 3 0.025
regulation of cellular component biogenesis GO:0044087 201 0.025
response to mercury ion GO:0046689 3 0.025
tube morphogenesis GO:0035239 191 0.025
regulation of epithelial cell differentiation GO:0030856 4 0.025
kidney morphogenesis GO:0060993 3 0.025
programmed cell death GO:0012501 257 0.024
response to biotic stimulus GO:0009607 294 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
response to nitrogen compound GO:1901698 90 0.024
salivary gland morphogenesis GO:0007435 145 0.023
compound eye development GO:0048749 307 0.022
notch signaling pathway GO:0007219 120 0.022
regulation of intracellular signal transduction GO:1902531 236 0.022
autophagic cell death GO:0048102 83 0.022
innate immune response GO:0045087 144 0.022
regulation of cellular amine metabolic process GO:0033238 3 0.022
taxis GO:0042330 304 0.022
nephron tubule development GO:0072080 3 0.021
imaginal disc derived appendage morphogenesis GO:0035114 395 0.021
wound healing GO:0042060 75 0.021
gland development GO:0048732 191 0.021
forebrain development GO:0030900 2 0.021
response to organonitrogen compound GO:0010243 75 0.021
regulation of notch signaling pathway GO:0008593 100 0.021
nephron epithelium morphogenesis GO:0072088 3 0.021
response to glucose GO:0009749 2 0.021
cellular ketone metabolic process GO:0042180 24 0.021
post embryonic appendage morphogenesis GO:0035120 385 0.020
protein complex biogenesis GO:0070271 201 0.020
nephron morphogenesis GO:0072028 3 0.020
regulation of cellular ketone metabolic process GO:0010565 3 0.020
cellular response to molecule of bacterial origin GO:0071219 3 0.020
response to radiation GO:0009314 155 0.020
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.020
cellular catabolic process GO:0044248 372 0.020
response to light stimulus GO:0009416 124 0.020
polyol biosynthetic process GO:0046173 3 0.020
catabolic process GO:0009056 409 0.020
growth GO:0040007 359 0.019
gland morphogenesis GO:0022612 145 0.019
organic substance catabolic process GO:1901575 308 0.019
mesenchymal cell differentiation GO:0048762 1 0.019
multi multicellular organism process GO:0044706 123 0.019
cell cell signaling involved in cell fate commitment GO:0045168 210 0.019
cell proliferation GO:0008283 299 0.019
columnar cuboidal epithelial cell development GO:0002066 249 0.019
response to external biotic stimulus GO:0043207 293 0.019
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.018
regulation of multicellular organismal development GO:2000026 414 0.018
eye development GO:0001654 323 0.018
single organism biosynthetic process GO:0044711 206 0.018
positive regulation of cell migration GO:0030335 2 0.018
histolysis GO:0007559 102 0.018
immune response GO:0006955 246 0.018
ovarian follicle cell development GO:0030707 248 0.018
developmental growth GO:0048589 280 0.018
tissue death GO:0016271 102 0.018
phagocytosis GO:0006909 215 0.018
cell death GO:0008219 279 0.018
exocrine system development GO:0035272 162 0.018
lateral inhibition GO:0046331 206 0.018
regulation of cell development GO:0060284 215 0.018
amine metabolic process GO:0009308 12 0.018
negative regulation of cell communication GO:0010648 223 0.017
carboxylic acid metabolic process GO:0019752 92 0.017
regulation of synapse structure and activity GO:0050803 128 0.017
positive regulation of response to stimulus GO:0048584 323 0.017
cellular amine metabolic process GO:0044106 12 0.017
cellular component assembly involved in morphogenesis GO:0010927 151 0.017
response to organic cyclic compound GO:0014070 89 0.017
organic acid metabolic process GO:0006082 103 0.017
cellular response to lipopolysaccharide GO:0071222 3 0.017
dephosphorylation GO:0016311 51 0.017
positive regulation of macromolecule metabolic process GO:0010604 405 0.017
oxoacid metabolic process GO:0043436 103 0.017
negative regulation of cellular biosynthetic process GO:0031327 277 0.017
response to alcohol GO:0097305 95 0.017
sensory organ morphogenesis GO:0090596 260 0.016
neurological system process GO:0050877 358 0.016
response to organophosphorus GO:0046683 2 0.016
positive regulation of signal transduction GO:0009967 223 0.016
small gtpase mediated signal transduction GO:0007264 88 0.016
phosphorylation GO:0016310 294 0.016
macromolecular complex assembly GO:0065003 256 0.016
ras protein signal transduction GO:0007265 88 0.016
salivary gland histolysis GO:0035070 88 0.016
positive regulation of developmental growth GO:0048639 62 0.016
salivary gland development GO:0007431 162 0.016
regionalization GO:0003002 416 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.015
organ growth GO:0035265 56 0.015
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.015
negative regulation of developmental process GO:0051093 201 0.015
protein complex assembly GO:0006461 200 0.015
ribonucleoside triphosphate metabolic process GO:0009199 119 0.015
carbohydrate derivative metabolic process GO:1901135 217 0.015
positive regulation of lipid storage GO:0010884 4 0.015
negative regulation of gene expression GO:0010629 387 0.015
response to wounding GO:0009611 94 0.015
developmental programmed cell death GO:0010623 138 0.015
cell fate determination GO:0001709 91 0.015
actin cytoskeleton organization GO:0030036 206 0.015
nephron tubule morphogenesis GO:0072078 3 0.015
regulation of nervous system development GO:0051960 248 0.015
appendage development GO:0048736 401 0.015
cellular response to oxygen containing compound GO:1901701 79 0.015
response to endogenous stimulus GO:0009719 119 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.015
positive regulation of biosynthetic process GO:0009891 316 0.015
axis specification GO:0009798 167 0.015
negative regulation of cellular component organization GO:0051129 108 0.015
fat soluble vitamin metabolic process GO:0006775 1 0.015
multicellular organismal aging GO:0010259 140 0.014
cellular amino acid metabolic process GO:0006520 61 0.014
regulation of vesicle mediated transport GO:0060627 59 0.014
connective tissue development GO:0061448 3 0.014
negative regulation of nervous system development GO:0051961 92 0.014
protein dna complex subunit organization GO:0071824 86 0.014
mating GO:0007618 120 0.014
segmentation GO:0035282 207 0.014
adult behavior GO:0030534 137 0.014
immune system process GO:0002376 347 0.014
eye morphogenesis GO:0048592 260 0.014
molting cycle chitin based cuticle GO:0007591 56 0.014
mesenchymal cell development GO:0014031 1 0.014
nucleoside phosphate metabolic process GO:0006753 162 0.014
positive regulation of cell motility GO:2000147 3 0.014
macromolecule catabolic process GO:0009057 161 0.014
telencephalon development GO:0021537 2 0.014
regulation of transport GO:0051049 181 0.014
small molecule metabolic process GO:0044281 305 0.014
aging GO:0007568 143 0.014
proteolysis GO:0006508 192 0.014
positive regulation of rna metabolic process GO:0051254 271 0.014
regulation of developmental growth GO:0048638 174 0.014
vitamin biosynthetic process GO:0009110 1 0.014
tissue morphogenesis GO:0048729 297 0.014
response to hexose GO:0009746 3 0.014
negative regulation of biosynthetic process GO:0009890 277 0.014
actin filament based process GO:0030029 220 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.013
regulation of synapse organization GO:0050807 110 0.013
response to extracellular stimulus GO:0009991 116 0.013
appendage morphogenesis GO:0035107 397 0.013
striated muscle adaptation GO:0014888 1 0.013
cellular macromolecular complex assembly GO:0034622 153 0.013
male gamete generation GO:0048232 201 0.013
organonitrogen compound metabolic process GO:1901564 318 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.013
single organism behavior GO:0044708 391 0.013
regulation of response to stress GO:0080134 200 0.013
heterocycle catabolic process GO:0046700 166 0.013
positive regulation of cell communication GO:0010647 250 0.013
regulation of synapse assembly GO:0051963 94 0.013
apoptotic process GO:0006915 159 0.013
positive regulation of nucleic acid templated transcription GO:1903508 266 0.013
response to monosaccharide GO:0034284 4 0.013
regulation of cell substrate adhesion GO:0010810 2 0.013
cellular response to mechanical stimulus GO:0071260 2 0.013
cellular response to uv GO:0034644 12 0.013
cholesterol transport GO:0030301 2 0.013
positive regulation of catabolic process GO:0009896 105 0.013
nucleotide metabolic process GO:0009117 161 0.013
organophosphate metabolic process GO:0019637 195 0.013
hindbrain development GO:0030902 2 0.013
positive regulation of cellular biosynthetic process GO:0031328 316 0.013
chromosome segregation GO:0007059 157 0.013
regulation of programmed cell death GO:0043067 152 0.013
hormone catabolic process GO:0042447 3 0.012
positive regulation of signaling GO:0023056 243 0.012
epithelial cell development GO:0002064 274 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
vitamin metabolic process GO:0006766 2 0.012
regulation of localization GO:0032879 275 0.012
tube development GO:0035295 244 0.012
benzene containing compound metabolic process GO:0042537 3 0.012
cellular response to external stimulus GO:0071496 66 0.012
regulation of cell cycle process GO:0010564 181 0.012
response to other organism GO:0051707 293 0.012
hematopoietic progenitor cell differentiation GO:0002244 1 0.012
molting cycle GO:0042303 56 0.012
regulation of ras protein signal transduction GO:0046578 93 0.012
cellular response to endogenous stimulus GO:0071495 80 0.012
negative regulation of synapse assembly GO:0051964 39 0.012
anion homeostasis GO:0055081 3 0.012
anterior posterior axis specification GO:0009948 109 0.012
establishment of localization in cell GO:0051649 402 0.012
homeostatic process GO:0042592 199 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
response to nutrient levels GO:0031667 114 0.012
response to alkaloid GO:0043279 26 0.012
response to high light intensity GO:0009644 1 0.012
limb development GO:0060173 1 0.012
protein transport GO:0015031 155 0.012
detection of stimulus GO:0051606 156 0.012
negative regulation of cellular metabolic process GO:0031324 382 0.012
response to lipid GO:0033993 38 0.012
digestive tract development GO:0048565 149 0.012
humoral immune response GO:0006959 117 0.012
open tracheal system development GO:0007424 204 0.011
pigmentation GO:0043473 75 0.011
cell projection assembly GO:0030031 94 0.011
regulation of multi organism process GO:0043900 131 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
imaginal disc derived wing vein specification GO:0007474 48 0.011
compound eye morphogenesis GO:0001745 249 0.011
positive regulation of transport GO:0051050 92 0.011
secretion GO:0046903 109 0.011
neuropeptide signaling pathway GO:0007218 45 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
neuron projection guidance GO:0097485 241 0.011
endomembrane system organization GO:0010256 119 0.011
regulation of immune response GO:0050776 118 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.011
neutral lipid biosynthetic process GO:0046460 2 0.011
chorion containing eggshell formation GO:0007304 105 0.011
rna localization GO:0006403 115 0.011
mitotic cytokinesis GO:0000281 50 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.011
regulation of neurogenesis GO:0050767 158 0.011
tor signaling GO:0031929 32 0.011
digestive tract morphogenesis GO:0048546 127 0.011
muscle tissue morphogenesis GO:0060415 2 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
eye photoreceptor cell development GO:0042462 81 0.011
regulation of lipid transport GO:0032368 3 0.011
embryonic pattern specification GO:0009880 174 0.011
salivary gland cell autophagic cell death GO:0035071 83 0.011
defense response to bacterium GO:0042742 178 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
establishment of protein localization GO:0045184 163 0.011
regulation of defense response GO:0031347 102 0.010
immune response activating signal transduction GO:0002757 2 0.010
camera type eye morphogenesis GO:0048593 2 0.010
activation of innate immune response GO:0002218 4 0.010
renal tubule development GO:0061326 64 0.010
negative regulation of notch signaling pathway GO:0045746 41 0.010
limb morphogenesis GO:0035108 1 0.010
oxidoreduction coenzyme metabolic process GO:0006733 2 0.010
defense response to gram negative bacterium GO:0050829 94 0.010
cellular response to carbohydrate stimulus GO:0071322 4 0.010
cellular macromolecule localization GO:0070727 220 0.010
regulation of epidermal cell differentiation GO:0045604 3 0.010
immune response regulating signaling pathway GO:0002764 2 0.010
androgen metabolic process GO:0008209 1 0.010
tripartite regional subdivision GO:0007351 103 0.010
positive regulation of gene expression GO:0010628 290 0.010
regulation of apoptotic process GO:0042981 130 0.010
protein dna complex assembly GO:0065004 63 0.010
regulation of organ growth GO:0046620 42 0.010
organic cyclic compound catabolic process GO:1901361 168 0.010
chemotaxis GO:0006935 249 0.010
cellular lipid metabolic process GO:0044255 83 0.010
positive regulation of cellular catabolic process GO:0031331 95 0.010
negative regulation of cell death GO:0060548 81 0.010
compound eye photoreceptor cell differentiation GO:0001751 140 0.010
regulation of cell cycle GO:0051726 291 0.010
establishment or maintenance of cell polarity GO:0007163 167 0.010
organelle fission GO:0048285 340 0.010
positive regulation of apoptotic signaling pathway GO:2001235 4 0.010

TwdlM disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.054
hypophosphatasia DOID:14213 0 0.046
cardiovascular system disease DOID:1287 0 0.020
nervous system disease DOID:863 0 0.019
disease of metabolism DOID:0014667 0 0.019
hypertension DOID:10763 0 0.015
artery disease DOID:0050828 0 0.015
vascular disease DOID:178 0 0.015
inherited metabolic disorder DOID:655 0 0.014
acquired metabolic disease DOID:0060158 0 0.013
musculoskeletal system disease DOID:17 0 0.012
central nervous system disease DOID:331 0 0.011
essential hypertension DOID:10825 0 0.011
carbohydrate metabolism disease DOID:0050013 0 0.011
glucose metabolism disease DOID:4194 0 0.011
urinary system disease DOID:18 0 0.010
diabetes mellitus DOID:9351 0 0.010
type 2 diabetes mellitus DOID:9352 0 0.010