Drosophila melanogaster

19 known processes

Ho (Dmel_CG14716)

Heme oxygenase

(Aliases: CG14716,Dmel\CG14716,DmHO,CT34507,HO)

Ho biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vesicle organization GO:0016050 44 0.155
negative regulation of gene expression GO:0010629 387 0.110
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.102
ubiquitin dependent protein catabolic process GO:0006511 78 0.101
catabolic process GO:0009056 409 0.098
post embryonic appendage morphogenesis GO:0035120 385 0.091
cellular protein catabolic process GO:0044257 83 0.077
protein catabolic process GO:0030163 101 0.076
macromolecule catabolic process GO:0009057 161 0.072
negative regulation of cellular metabolic process GO:0031324 382 0.065
proteolysis GO:0006508 192 0.063
regulation of response to stress GO:0080134 200 0.062
macroautophagy GO:0016236 42 0.058
cellular catabolic process GO:0044248 372 0.058
enzyme linked receptor protein signaling pathway GO:0007167 179 0.056
regulation of multicellular organismal development GO:2000026 414 0.054
regulation of cellular catabolic process GO:0031329 157 0.054
intracellular signal transduction GO:0035556 300 0.053
organic substance catabolic process GO:1901575 308 0.049
modification dependent protein catabolic process GO:0019941 78 0.049
response to other organism GO:0051707 293 0.048
response to external biotic stimulus GO:0043207 293 0.047
regulation of cell differentiation GO:0045595 302 0.047
wing disc morphogenesis GO:0007472 344 0.047
regulation of transport GO:0051049 181 0.045
eye development GO:0001654 323 0.045
positive regulation of signal transduction GO:0009967 223 0.045
protein modification process GO:0036211 438 0.044
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.042
response to biotic stimulus GO:0009607 294 0.040
immune system process GO:0002376 347 0.040
transcription from rna polymerase ii promoter GO:0006366 368 0.039
vesicle mediated transport GO:0016192 381 0.039
appendage morphogenesis GO:0035107 397 0.038
secretion GO:0046903 109 0.037
protein modification by small protein conjugation or removal GO:0070647 106 0.037
modification dependent macromolecule catabolic process GO:0043632 79 0.037
regulation of proteolysis GO:0030162 87 0.036
homeostatic process GO:0042592 199 0.036
positive regulation of response to stimulus GO:0048584 323 0.036
cellular protein modification process GO:0006464 438 0.035
immune response GO:0006955 246 0.035
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.035
regulation of mitotic cell cycle GO:0007346 190 0.035
positive regulation of catabolic process GO:0009896 105 0.034
columnar cuboidal epithelial cell development GO:0002066 249 0.034
protein modification by small protein conjugation GO:0032446 79 0.032
appendage development GO:0048736 401 0.031
secretion by cell GO:0032940 101 0.031
regulation of intracellular signal transduction GO:1902531 236 0.031
cellular response to chemical stimulus GO:0070887 199 0.031
positive regulation of cellular catabolic process GO:0031331 95 0.030
regulation of catabolic process GO:0009894 170 0.030
regulation of cell cycle GO:0051726 291 0.029
regulation of protein metabolic process GO:0051246 256 0.028
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.028
compound eye morphogenesis GO:0001745 249 0.028
compound eye development GO:0048749 307 0.028
positive regulation of cell communication GO:0010647 250 0.028
regulation of endopeptidase activity GO:0052548 36 0.028
mitotic sister chromatid segregation GO:0000070 87 0.028
phosphorylation GO:0016310 294 0.028
response to bacterium GO:0009617 198 0.028
establishment of localization in cell GO:0051649 402 0.027
protein transport GO:0015031 155 0.027
regulation of multi organism process GO:0043900 131 0.027
cellular component assembly involved in morphogenesis GO:0010927 151 0.026
male gamete generation GO:0048232 201 0.026
organonitrogen compound metabolic process GO:1901564 318 0.026
negative regulation of response to stimulus GO:0048585 258 0.025
positive regulation of signaling GO:0023056 243 0.025
regulation of secretion GO:0051046 44 0.025
chemical homeostasis GO:0048878 92 0.025
regulation of response to external stimulus GO:0032101 115 0.024
organelle assembly GO:0070925 198 0.024
segmentation GO:0035282 207 0.024
protein ubiquitination GO:0016567 70 0.024
spermatogenesis GO:0007283 200 0.024
regulation of nervous system development GO:0051960 248 0.023
signal release GO:0023061 49 0.023
small molecule metabolic process GO:0044281 305 0.023
regulation of synaptic transmission GO:0050804 69 0.023
mitotic spindle organization GO:0007052 220 0.023
regulation of immune system process GO:0002682 176 0.023
regulation of cellular response to stress GO:0080135 89 0.023
erbb signaling pathway GO:0038127 58 0.023
spindle organization GO:0007051 253 0.023
autophagy GO:0006914 108 0.022
regulation of autophagy GO:0010506 62 0.022
developmental growth GO:0048589 280 0.022
cation transmembrane transport GO:0098655 88 0.021
compound eye photoreceptor cell differentiation GO:0001751 140 0.021
cellular component disassembly GO:0022411 46 0.021
regulation of anatomical structure size GO:0090066 163 0.021
single organism intracellular transport GO:1902582 207 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.021
negative regulation of transcription dna templated GO:0045892 237 0.021
organelle fission GO:0048285 340 0.021
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.021
negative regulation of cell communication GO:0010648 223 0.021
imaginal disc derived wing morphogenesis GO:0007476 337 0.021
ras protein signal transduction GO:0007265 88 0.020
kidney morphogenesis GO:0060993 3 0.020
regulation of response to biotic stimulus GO:0002831 63 0.020
immune effector process GO:0002252 98 0.020
cellular macromolecule catabolic process GO:0044265 136 0.020
kidney development GO:0001822 3 0.020
regulation of epithelial cell proliferation GO:0050678 4 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.019
sensory perception GO:0007600 196 0.019
photoreceptor cell differentiation GO:0046530 170 0.019
negative regulation of nucleic acid templated transcription GO:1903507 240 0.019
phagocytosis GO:0006909 215 0.018
establishment of protein localization GO:0045184 163 0.018
positive regulation of molecular function GO:0044093 136 0.018
spermatid differentiation GO:0048515 114 0.018
camera type eye development GO:0043010 4 0.018
cellular amino acid metabolic process GO:0006520 61 0.018
proteasomal protein catabolic process GO:0010498 59 0.018
regulation of secretion by cell GO:1903530 39 0.018
cellular homeostasis GO:0019725 80 0.018
regulation of peptidase activity GO:0052547 39 0.018
regulation of hydrolase activity GO:0051336 97 0.018
programmed cell death GO:0012501 257 0.018
locomotory behavior GO:0007626 176 0.017
regulation of ras protein signal transduction GO:0046578 93 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.017
negative regulation of cellular biosynthetic process GO:0031327 277 0.017
cellular response to organic substance GO:0071310 132 0.017
nucleotide metabolic process GO:0009117 161 0.017
positive regulation of apoptotic signaling pathway GO:2001235 4 0.017
histolysis GO:0007559 102 0.017
small gtpase mediated signal transduction GO:0007264 88 0.017
neurological system process GO:0050877 358 0.017
wnt signaling pathway GO:0016055 98 0.017
cell death GO:0008219 279 0.017
cytoplasmic transport GO:0016482 130 0.017
posttranscriptional gene silencing by rna GO:0035194 45 0.017
regulation of localization GO:0032879 275 0.017
defense response to other organism GO:0098542 225 0.017
regulation of synapse organization GO:0050807 110 0.017
negative regulation of cellular protein metabolic process GO:0032269 85 0.017
synaptic transmission GO:0007268 288 0.016
regulation of hormone levels GO:0010817 40 0.016
negative regulation of biosynthetic process GO:0009890 277 0.016
regulation of cell cycle process GO:0010564 181 0.016
protein complex biogenesis GO:0070271 201 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.016
negative regulation of protein metabolic process GO:0051248 85 0.016
protein localization GO:0008104 284 0.016
single organism biosynthetic process GO:0044711 206 0.016
endomembrane system organization GO:0010256 119 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
cellular response to hexose stimulus GO:0071331 1 0.015
imaginal disc derived appendage development GO:0048737 399 0.015
regulation of defense response GO:0031347 102 0.015
body morphogenesis GO:0010171 2 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
negative regulation of rna biosynthetic process GO:1902679 240 0.015
negative regulation of signaling GO:0023057 219 0.015
pigment metabolic process GO:0042440 84 0.015
sensory organ morphogenesis GO:0090596 260 0.015
macromolecular complex assembly GO:0065003 256 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.015
positive regulation of protein metabolic process GO:0051247 128 0.015
positive regulation of cell death GO:0010942 69 0.015
regulation of developmental growth GO:0048638 174 0.015
nucleobase containing compound catabolic process GO:0034655 165 0.014
regulation of cellular component movement GO:0051270 42 0.014
developmental programmed cell death GO:0010623 138 0.014
regulation of humoral immune response GO:0002920 51 0.014
apoptotic process GO:0006915 159 0.014
intracellular transport GO:0046907 228 0.014
organic substance transport GO:0071702 257 0.014
positive regulation of programmed cell death GO:0043068 62 0.014
blastoderm segmentation GO:0007350 159 0.014
developmental maturation GO:0021700 172 0.014
positive regulation of developmental growth GO:0048639 62 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.014
sister chromatid segregation GO:0000819 92 0.014
epithelial cell development GO:0002064 274 0.014
single organism membrane budding GO:1902591 2 0.014
lipid metabolic process GO:0006629 121 0.014
sperm individualization GO:0007291 48 0.014
positive regulation of cellular protein catabolic process GO:1903364 24 0.014
cellular response to sterol depletion GO:0071501 3 0.014
camera type eye morphogenesis GO:0048593 2 0.014
regulation of molecular function GO:0065009 217 0.014
protein localization to organelle GO:0033365 82 0.014
hematopoietic or lymphoid organ development GO:0048534 57 0.013
forebrain development GO:0030900 2 0.013
embryonic pattern specification GO:0009880 174 0.013
cell proliferation GO:0008283 299 0.013
eye morphogenesis GO:0048592 260 0.013
negative regulation of cellular component organization GO:0051129 108 0.013
compound eye photoreceptor development GO:0042051 78 0.013
positive regulation of macromolecule metabolic process GO:0010604 405 0.013
defense response to bacterium GO:0042742 178 0.013
spermatid development GO:0007286 98 0.013
regulation of cell development GO:0060284 215 0.013
defense response GO:0006952 300 0.013
gtp metabolic process GO:0046039 72 0.013
eye photoreceptor cell differentiation GO:0001754 145 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.013
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.013
organic acid metabolic process GO:0006082 103 0.013
oocyte axis specification GO:0007309 108 0.013
positive regulation of secretion GO:0051047 22 0.013
chromosome segregation GO:0007059 157 0.013
regulation of catalytic activity GO:0050790 185 0.013
cell cycle phase transition GO:0044770 140 0.013
regulation of innate immune response GO:0045088 71 0.013
oxoacid metabolic process GO:0043436 103 0.013
mitotic dna integrity checkpoint GO:0044774 75 0.013
gene silencing by rna GO:0031047 57 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
protein secretion GO:0009306 45 0.012
antimicrobial humoral response GO:0019730 99 0.012
humoral immune response GO:0006959 117 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
cell motility GO:0048870 251 0.012
membrane organization GO:0061024 112 0.012
dendrite morphogenesis GO:0048813 199 0.012
tissue death GO:0016271 102 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
positive regulation of transport GO:0051050 92 0.012
regulation of cellular amide metabolic process GO:0034248 39 0.012
melanin metabolic process GO:0006582 47 0.012
regulation of programmed cell death GO:0043067 152 0.012
salivary gland morphogenesis GO:0007435 145 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
negative regulation of rna metabolic process GO:0051253 251 0.012
regulation of cellular protein metabolic process GO:0032268 243 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
cation transport GO:0006812 110 0.012
regulation of cytoskeleton organization GO:0051493 89 0.012
response to hexose GO:0009746 3 0.012
negative regulation of cell cycle phase transition GO:1901988 103 0.012
cellular response to mechanical stimulus GO:0071260 2 0.012
regulation of immune response GO:0050776 118 0.011
cellular chemical homeostasis GO:0055082 40 0.011
muscle system process GO:0003012 21 0.011
regulation of cellular protein catabolic process GO:1903362 44 0.011
negative regulation of cell cycle process GO:0010948 109 0.011
epithelial cell differentiation GO:0030855 322 0.011
negative regulation of intracellular signal transduction GO:1902532 57 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
localization of cell GO:0051674 257 0.011
mitotic nuclear division GO:0007067 213 0.011
cholesterol homeostasis GO:0042632 3 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.011
regulation of apoptotic process GO:0042981 130 0.011
response to extracellular stimulus GO:0009991 116 0.011
negative regulation of signal transduction GO:0009968 206 0.011
regulation of endocytosis GO:0030100 37 0.011
negative regulation of cell death GO:0060548 81 0.011
regulation of organelle organization GO:0033043 196 0.011
guanosine containing compound catabolic process GO:1901069 74 0.011
regulation of neurogenesis GO:0050767 158 0.011
death GO:0016265 284 0.011
nucleoside metabolic process GO:0009116 127 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
imaginal disc derived appendage morphogenesis GO:0035114 395 0.011
cellular response to external stimulus GO:0071496 66 0.011
regulation of antimicrobial peptide production GO:0002784 44 0.011
mitochondrion organization GO:0007005 65 0.011
negative regulation of mitotic cell cycle GO:0045930 109 0.011
melanization defense response GO:0035006 45 0.011
autophagic cell death GO:0048102 83 0.011
ovarian follicle cell development GO:0030707 248 0.011
response to light stimulus GO:0009416 124 0.011
learning or memory GO:0007611 141 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.011
mesenchymal cell differentiation GO:0048762 1 0.011
regionalization GO:0003002 416 0.010
cellular response to carbohydrate stimulus GO:0071322 4 0.010
cellular response to starvation GO:0009267 61 0.010
protein maturation GO:0051604 71 0.010
regulation of cellular localization GO:0060341 136 0.010
positive regulation of multicellular organismal process GO:0051240 143 0.010
positive regulation of phosphorus metabolic process GO:0010562 139 0.010
response to nutrient levels GO:0031667 114 0.010
peptide metabolic process GO:0006518 80 0.010
aromatic compound catabolic process GO:0019439 166 0.010
sensory perception of pain GO:0019233 4 0.010
peripheral nervous system development GO:0007422 52 0.010
positive regulation of exocytosis GO:0045921 4 0.010
telencephalon development GO:0021537 2 0.010

Ho disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
cardiovascular system disease DOID:1287 0 0.025
disease of metabolism DOID:0014667 0 0.017
nervous system disease DOID:863 0 0.017
urinary system disease DOID:18 0 0.017
inherited metabolic disorder DOID:655 0 0.016
sensory system disease DOID:0050155 0 0.014