Drosophila melanogaster

62 known processes

tho2 (Dmel_CG31671)

CG31671 gene product from transcript CG31671-RA

(Aliases: Tho2,CG31671,THO2,Dmel\CG31671,CG4263)

tho2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oocyte differentiation GO:0009994 145 0.998
oocyte development GO:0048599 124 0.993
pole plasm mrna localization GO:0019094 49 0.993
oocyte axis specification GO:0007309 108 0.967
pole plasm oskar mrna localization GO:0045451 46 0.965
rna localization GO:0006403 115 0.953
oocyte construction GO:0007308 112 0.952
pole plasm assembly GO:0007315 61 0.895
pole plasm rna localization GO:0007316 52 0.857
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.689
oocyte anterior posterior axis specification GO:0007314 72 0.669
cytoplasm organization GO:0007028 64 0.667
mitotic spindle organization GO:0007052 220 0.625
maternal determination of anterior posterior axis embryo GO:0008358 74 0.560
intracellular mrna localization GO:0008298 66 0.548
regulation of mrna metabolic process GO:1903311 72 0.531
mrna metabolic process GO:0016071 124 0.467
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.461
blastoderm segmentation GO:0007350 159 0.430
anterior posterior pattern specification GO:0009952 136 0.415
regionalization GO:0003002 416 0.398
negative regulation of gene expression GO:0010629 387 0.384
cell maturation GO:0048469 144 0.364
mrna processing GO:0006397 104 0.339
positive regulation of macromolecule metabolic process GO:0010604 405 0.296
growth GO:0040007 359 0.277
negative regulation of cellular biosynthetic process GO:0031327 277 0.260
spindle organization GO:0007051 253 0.255
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.252
gene silencing by mirna GO:0035195 22 0.250
circulatory system development GO:0072359 82 0.247
cell proliferation GO:0008283 299 0.246
anterior posterior axis specification GO:0009948 109 0.242
embryonic pattern specification GO:0009880 174 0.236
regulation of protein metabolic process GO:0051246 256 0.236
anterior posterior axis specification embryo GO:0008595 103 0.229
multi organism behavior GO:0051705 175 0.229
multicellular organismal reproductive behavior GO:0033057 110 0.228
negative regulation of rna biosynthetic process GO:1902679 240 0.191
cellular macromolecule localization GO:0070727 220 0.185
rna splicing GO:0008380 83 0.180
rna splicing via transesterification reactions GO:0000375 73 0.179
tripartite regional subdivision GO:0007351 103 0.176
regulation of mrna processing GO:0050684 71 0.165
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.162
dorsal ventral axis specification GO:0009950 66 0.160
segmentation GO:0035282 207 0.160
dna metabolic process GO:0006259 227 0.159
single organism cellular localization GO:1902580 180 0.158
posttranscriptional gene silencing by rna GO:0035194 45 0.155
gene silencing GO:0016458 138 0.155
mrna splicing via spliceosome GO:0000398 73 0.151
head development GO:0060322 135 0.142
positive regulation of cellular biosynthetic process GO:0031328 316 0.142
regulation of mrna splicing via spliceosome GO:0048024 64 0.141
regulation of reproductive process GO:2000241 54 0.136
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.131
axis specification GO:0009798 167 0.130
embryonic axis specification GO:0000578 107 0.128
positive regulation of gene expression GO:0010628 290 0.125
establishment of nucleus localization GO:0040023 26 0.125
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.125
developmental maturation GO:0021700 172 0.124
central nervous system development GO:0007417 201 0.121
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.120
single fertilization GO:0007338 24 0.118
establishment of localization in cell GO:0051649 402 0.115
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.113
nucleus localization GO:0051647 34 0.110
brain development GO:0007420 120 0.106
nuclear transcribed mrna catabolic process GO:0000956 24 0.105
mrna transport GO:0051028 15 0.105
axon development GO:0061564 297 0.100
regulation of multi organism process GO:0043900 131 0.099
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.093
regulation of cell differentiation GO:0045595 302 0.084
organic substance transport GO:0071702 257 0.084
regulation of multicellular organismal development GO:2000026 414 0.083
vesicle mediated transport GO:0016192 381 0.082
regulation of gene expression epigenetic GO:0040029 128 0.081
establishment of rna localization GO:0051236 47 0.080
regulation of rna splicing GO:0043484 69 0.079
dna templated transcription elongation GO:0006354 18 0.075
death GO:0016265 284 0.074
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.072
regulation of oocyte development GO:0060281 27 0.071
immune system process GO:0002376 347 0.071
gonad development GO:0008406 50 0.070
development of primary sexual characteristics GO:0045137 50 0.070
negative regulation of biosynthetic process GO:0009890 277 0.070
protein modification process GO:0036211 438 0.069
nuclear migration GO:0007097 20 0.067
endocytosis GO:0006897 310 0.066
aromatic compound catabolic process GO:0019439 166 0.066
dna methylation or demethylation GO:0044728 4 0.064
neuron projection guidance GO:0097485 241 0.063
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 8 0.063
alternative mrna splicing via spliceosome GO:0000380 60 0.063
small molecule metabolic process GO:0044281 305 0.059
response to biotic stimulus GO:0009607 294 0.058
cell death GO:0008219 279 0.057
positive regulation of rna metabolic process GO:0051254 271 0.056
regulation of cellular protein metabolic process GO:0032268 243 0.055
regulation of nuclear division GO:0051783 58 0.055
oocyte microtubule cytoskeleton organization GO:0016325 35 0.053
posttranscriptional regulation of gene expression GO:0010608 145 0.052
dorsal ventral pattern formation GO:0009953 133 0.052
taxis GO:0042330 304 0.051
negative regulation of rna metabolic process GO:0051253 251 0.050
negative regulation of cellular metabolic process GO:0031324 382 0.050
negative regulation of nucleic acid templated transcription GO:1903507 240 0.050
larval development GO:0002164 104 0.050
regulation of molecular function GO:0065009 217 0.048
organelle localization GO:0051640 148 0.044
axon guidance GO:0007411 233 0.042
rna transport GO:0050658 46 0.041
regulation of localization GO:0032879 275 0.040
germarium derived oocyte differentiation GO:0030706 29 0.039
cell cycle phase transition GO:0044770 140 0.037
forebrain development GO:0030900 2 0.037
reproductive structure development GO:0048608 74 0.035
oocyte dorsal ventral axis specification GO:0007310 34 0.034
positive regulation of biosynthetic process GO:0009891 316 0.034
sex differentiation GO:0007548 81 0.033
body morphogenesis GO:0010171 2 0.033
translation GO:0006412 69 0.033
protein localization GO:0008104 284 0.032
nucleobase containing compound catabolic process GO:0034655 165 0.032
germarium derived oocyte fate determination GO:0007294 26 0.032
oxoacid metabolic process GO:0043436 103 0.032
mrna 3 end processing GO:0031124 28 0.031
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.031
single organism behavior GO:0044708 391 0.031
intracellular signal transduction GO:0035556 300 0.031
cellular response to chemical stimulus GO:0070887 199 0.030
signal transduction by phosphorylation GO:0023014 107 0.030
chromatin silencing GO:0006342 76 0.029
atp metabolic process GO:0046034 49 0.029
neurological system process GO:0050877 358 0.028
oocyte fate determination GO:0030716 27 0.028
nuclear division GO:0000280 332 0.028
peptidyl proline modification GO:0018208 3 0.028
cardiovascular system development GO:0072358 82 0.027
developmental growth GO:0048589 280 0.027
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.027
homeostatic process GO:0042592 199 0.026
positive regulation of nucleic acid templated transcription GO:1903508 266 0.026
positive regulation of transcription dna templated GO:0045893 266 0.026
dsrna fragmentation GO:0031050 15 0.026
response to other organism GO:0051707 293 0.025
organic substance catabolic process GO:1901575 308 0.025
axonogenesis GO:0007409 290 0.024
regulation of organelle organization GO:0033043 196 0.024
response to oxygen containing compound GO:1901700 200 0.024
organic cyclic compound catabolic process GO:1901361 168 0.024
cellular amino acid metabolic process GO:0006520 61 0.024
chromosome organization GO:0051276 360 0.024
posttranscriptional gene silencing GO:0016441 46 0.024
nucleobase containing compound transport GO:0015931 56 0.023
response to abiotic stimulus GO:0009628 341 0.023
programmed cell death GO:0012501 257 0.022
response to external biotic stimulus GO:0043207 293 0.022
bicoid mrna localization GO:0045450 8 0.022
positive regulation of rna biosynthetic process GO:1902680 266 0.022
heart development GO:0007507 82 0.021
regulation of programmed cell death GO:0043067 152 0.021
cellular nitrogen compound catabolic process GO:0044270 165 0.021
negative regulation of protein metabolic process GO:0051248 85 0.021
regulation of gene silencing GO:0060968 63 0.021
cellular response to oxygen containing compound GO:1901701 79 0.021
multi organism reproductive behavior GO:0044705 121 0.020
regulation of cell death GO:0010941 173 0.019
regulation of meiosis GO:0040020 3 0.019
regulation of neuron projection development GO:0010975 69 0.019
regulation of developmental growth GO:0048638 174 0.019
positive regulation of signaling GO:0023056 243 0.019
macromolecule methylation GO:0043414 45 0.019
sister chromatid segregation GO:0000819 92 0.018
embryo development ending in birth or egg hatching GO:0009792 152 0.018
cell division GO:0051301 248 0.018
regulation of cell proliferation GO:0042127 163 0.018
dna alkylation GO:0006305 4 0.017
regulation of cell development GO:0060284 215 0.017
negative regulation of programmed cell death GO:0043069 72 0.017
positive regulation of cellular component organization GO:0051130 156 0.017
ribonucleoprotein complex subunit organization GO:0071826 28 0.017
regulation of catalytic activity GO:0050790 185 0.017
meiotic cell cycle GO:0051321 171 0.016
germarium derived egg chamber formation GO:0007293 101 0.016
production of mirnas involved in gene silencing by mirna GO:0035196 10 0.016
phagocytosis GO:0006909 215 0.016
maternal specification of dorsal ventral axis oocyte germ line encoded GO:0007311 4 0.016
spliceosomal complex assembly GO:0000245 1 0.016
gene silencing by rna GO:0031047 57 0.016
methylation GO:0032259 47 0.016
purine nucleoside monophosphate metabolic process GO:0009126 50 0.016
regulation of mrna 3 end processing GO:0031440 7 0.016
regulation of transport GO:0051049 181 0.016
multi multicellular organism process GO:0044706 123 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
organonitrogen compound metabolic process GO:1901564 318 0.015
reproductive system development GO:0061458 74 0.015
spinal cord development GO:0021510 1 0.015
cellular ketone metabolic process GO:0042180 24 0.015
regulation of dna templated transcription elongation GO:0032784 17 0.015
developmental pigmentation GO:0048066 68 0.015
positive regulation of response to stimulus GO:0048584 323 0.015
retina development in camera type eye GO:0060041 4 0.015
response to organic substance GO:0010033 284 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.014
apoptotic process GO:0006915 159 0.014
secretion GO:0046903 109 0.014
organic acid metabolic process GO:0006082 103 0.014
negative regulation of cell communication GO:0010648 223 0.014
cellular response to organic substance GO:0071310 132 0.014
negative regulation of signaling GO:0023057 219 0.013
rna processing GO:0006396 147 0.013
endomembrane system organization GO:0010256 119 0.013
positive regulation of developmental process GO:0051094 143 0.013
eye photoreceptor cell development GO:0042462 81 0.013
macromolecule catabolic process GO:0009057 161 0.013
karyosome formation GO:0030717 22 0.013
chemosensory behavior GO:0007635 106 0.013
negative regulation of transcription dna templated GO:0045892 237 0.013
regulation of immune system process GO:0002682 176 0.013
cell motility GO:0048870 251 0.013
meiotic cell cycle process GO:1903046 132 0.013
cell recognition GO:0008037 102 0.013
regulation of cell cycle process GO:0010564 181 0.013
protein alkylation GO:0008213 43 0.013
detection of stimulus GO:0051606 156 0.013
intracellular transport GO:0046907 228 0.012
wound healing GO:0042060 75 0.012
regulation of oskar mrna translation GO:0046011 8 0.012
mrna catabolic process GO:0006402 33 0.012
cellular protein modification process GO:0006464 438 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
female germ line cyst formation GO:0048135 42 0.012
production of sirna involved in rna interference GO:0030422 11 0.012
regulation of apoptotic process GO:0042981 130 0.012
mitotic cell cycle checkpoint GO:0007093 88 0.012
regulation of mitotic cell cycle GO:0007346 190 0.012
fertilization GO:0009566 26 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.011
cell type specific apoptotic process GO:0097285 38 0.011
positive regulation of signal transduction GO:0009967 223 0.011
centrosome organization GO:0051297 163 0.011
cellular response to lipid GO:0071396 20 0.011
single organism biosynthetic process GO:0044711 206 0.011
response to lipid GO:0033993 38 0.011
positive regulation of hydrolase activity GO:0051345 78 0.011
regulation of mitosis GO:0007088 56 0.011
ribonucleoprotein complex assembly GO:0022618 23 0.011
organelle fission GO:0048285 340 0.011
regulation of cell maturation GO:1903429 27 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
aggressive behavior GO:0002118 63 0.011
cell fate determination GO:0001709 91 0.011
golgi organization GO:0007030 66 0.011
rna 3 end processing GO:0031123 45 0.011
interspecies interaction between organisms GO:0044419 16 0.011
chromosome segregation GO:0007059 157 0.010
rna catabolic process GO:0006401 37 0.010
stem cell differentiation GO:0048863 117 0.010
protein secretion GO:0009306 45 0.010
ribose phosphate metabolic process GO:0019693 145 0.010
macromolecular complex assembly GO:0065003 256 0.010
organophosphate catabolic process GO:0046434 112 0.010
negative regulation of cellular protein metabolic process GO:0032269 85 0.010
nucleic acid transport GO:0050657 46 0.010
peptidyl amino acid modification GO:0018193 105 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 16 0.010

tho2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.111
nervous system disease DOID:863 0 0.012