Drosophila melanogaster

57 known processes

Hira (Dmel_CG12153)

CG12153 gene product from transcript CG12153-RA

(Aliases: Dmel\CG12153,CG12153,hira,HIRA,Dhh,ssm,dhira,dHira)

Hira biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single fertilization GO:0007338 24 0.995
male pronucleus assembly GO:0035039 6 0.972
fertilization GO:0009566 26 0.965
nucleus organization GO:0006997 45 0.927
negative regulation of gene expression epigenetic GO:0045814 77 0.678
chromatin organization GO:0006325 207 0.640
negative regulation of gene expression GO:0010629 387 0.506
Yeast
negative regulation of cellular biosynthetic process GO:0031327 277 0.491
Yeast
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.421
Yeast
chromatin remodeling GO:0006338 72 0.376
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.334
protein modification process GO:0036211 438 0.295
gene silencing GO:0016458 138 0.265
glycosyl compound catabolic process GO:1901658 112 0.260
nucleoside triphosphate catabolic process GO:0009143 108 0.260
ribonucleoside catabolic process GO:0042454 112 0.251
regulation of gene expression epigenetic GO:0040029 128 0.225
regulation of organelle organization GO:0033043 196 0.220
organophosphate metabolic process GO:0019637 195 0.186
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.179
Yeast
negative regulation of biosynthetic process GO:0009890 277 0.172
Yeast
purine nucleoside metabolic process GO:0042278 127 0.169
organonitrogen compound metabolic process GO:1901564 318 0.156
purine nucleoside triphosphate catabolic process GO:0009146 108 0.148
purine ribonucleotide catabolic process GO:0009154 109 0.146
negative regulation of nucleic acid templated transcription GO:1903507 240 0.144
Yeast
cellular protein modification process GO:0006464 438 0.138
negative regulation of cellular metabolic process GO:0031324 382 0.137
Yeast
nucleoside triphosphate metabolic process GO:0009141 120 0.130
nucleoside phosphate metabolic process GO:0006753 162 0.130
cellular nitrogen compound catabolic process GO:0044270 165 0.127
catabolic process GO:0009056 409 0.125
purine ribonucleotide metabolic process GO:0009150 145 0.123
positive regulation of nucleoside metabolic process GO:0045979 47 0.119
ribonucleoside triphosphate catabolic process GO:0009203 108 0.118
small molecule metabolic process GO:0044281 305 0.118
heterocycle catabolic process GO:0046700 166 0.117
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.116
nucleoside metabolic process GO:0009116 127 0.115
organelle fusion GO:0048284 46 0.115
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.113
chromatin silencing GO:0006342 76 0.113
aromatic compound catabolic process GO:0019439 166 0.111
purine nucleotide catabolic process GO:0006195 109 0.108
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.105
Yeast
ribonucleotide catabolic process GO:0009261 109 0.104
organic substance catabolic process GO:1901575 308 0.102
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.101
Yeast
negative regulation of rna metabolic process GO:0051253 251 0.098
Yeast
organonitrogen compound catabolic process GO:1901565 128 0.097
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.096
negative regulation of rna biosynthetic process GO:1902679 240 0.090
Yeast
oocyte development GO:0048599 124 0.088
regulation of dna metabolic process GO:0051052 34 0.087
carbohydrate derivative metabolic process GO:1901135 217 0.087
glycosyl compound metabolic process GO:1901657 127 0.084
positive regulation of molecular function GO:0044093 136 0.083
ribonucleoside triphosphate metabolic process GO:0009199 119 0.082
positive regulation of cellular biosynthetic process GO:0031328 316 0.082
regulation of small gtpase mediated signal transduction GO:0051056 93 0.081
dna recombination GO:0006310 32 0.080
positive regulation of gtpase activity GO:0043547 43 0.079
organophosphate catabolic process GO:0046434 112 0.077
nucleotide catabolic process GO:0009166 109 0.076
nucleoside phosphate catabolic process GO:1901292 110 0.075
regulation of phosphate metabolic process GO:0019220 210 0.075
regulation of ras protein signal transduction GO:0046578 93 0.074
nucleobase containing compound catabolic process GO:0034655 165 0.073
ribose phosphate metabolic process GO:0019693 145 0.072
regulation of protein metabolic process GO:0051246 256 0.071
ribonucleotide metabolic process GO:0009259 145 0.070
regulation of cellular catabolic process GO:0031329 157 0.068
carbohydrate derivative catabolic process GO:1901136 118 0.068
purine nucleotide metabolic process GO:0006163 146 0.067
dna metabolic process GO:0006259 227 0.065
purine containing compound catabolic process GO:0072523 112 0.065
axis specification GO:0009798 167 0.064
positive regulation of catalytic activity GO:0043085 118 0.063
regulation of protein modification process GO:0031399 112 0.062
regulation of cellular protein metabolic process GO:0032268 243 0.062
mitotic spindle organization GO:0007052 220 0.060
negative regulation of transcription dna templated GO:0045892 237 0.060
Yeast
purine nucleoside catabolic process GO:0006152 112 0.060
chromosome organization GO:0051276 360 0.059
regulation of phosphorus metabolic process GO:0051174 210 0.059
purine containing compound metabolic process GO:0072521 155 0.058
purine ribonucleoside metabolic process GO:0046128 127 0.058
heterochromatin organization GO:0070828 25 0.054
ras protein signal transduction GO:0007265 88 0.054
macromolecule catabolic process GO:0009057 161 0.052
small gtpase mediated signal transduction GO:0007264 88 0.052
purine ribonucleoside catabolic process GO:0046130 112 0.052
regulation of catabolic process GO:0009894 170 0.051
positive regulation of nucleic acid templated transcription GO:1903508 266 0.051
cellular macromolecule catabolic process GO:0044265 136 0.050
regulation of purine nucleotide metabolic process GO:1900542 62 0.047
embryo development ending in birth or egg hatching GO:0009792 152 0.046
Worm
regulation of hydrolase activity GO:0051336 97 0.046
imaginal disc derived appendage development GO:0048737 399 0.046
nucleotide metabolic process GO:0009117 161 0.046
positive regulation of catabolic process GO:0009896 105 0.046
cellular catabolic process GO:0044248 372 0.043
positive regulation of transcription dna templated GO:0045893 266 0.042
regulation of chromosome organization GO:0033044 64 0.042
protein catabolic process GO:0030163 101 0.041
histone modification GO:0016570 106 0.041
regulation of nucleotide catabolic process GO:0030811 48 0.040
cell division GO:0051301 248 0.039
regulation of nucleotide metabolic process GO:0006140 62 0.039
nucleoside catabolic process GO:0009164 112 0.039
positive regulation of organelle organization GO:0010638 65 0.039
guanosine containing compound catabolic process GO:1901069 74 0.039
organic cyclic compound catabolic process GO:1901361 168 0.038
anterior posterior axis specification GO:0009948 109 0.038
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.038
regulation of cell cycle GO:0051726 291 0.037
single organism catabolic process GO:0044712 228 0.037
posttranscriptional gene silencing by rna GO:0035194 45 0.036
regulation of cellular component biogenesis GO:0044087 201 0.036
female meiotic division GO:0007143 70 0.036
dna conformation change GO:0071103 105 0.035
protein localization GO:0008104 284 0.035
positive regulation of rna metabolic process GO:0051254 271 0.033
vesicle mediated transport GO:0016192 381 0.032
positive regulation of cellular catabolic process GO:0031331 95 0.032
ribonucleoside metabolic process GO:0009119 127 0.031
regulation of multi organism process GO:0043900 131 0.030
nucleobase containing small molecule metabolic process GO:0055086 174 0.030
dna alkylation GO:0006305 4 0.029
anterior posterior pattern specification GO:0009952 136 0.029
modification dependent protein catabolic process GO:0019941 78 0.028
ubiquitin dependent protein catabolic process GO:0006511 78 0.028
regulation of purine nucleotide catabolic process GO:0033121 48 0.028
regulation of molecular function GO:0065009 217 0.028
mitotic dna integrity checkpoint GO:0044774 75 0.027
appendage development GO:0048736 401 0.027
single organism cellular localization GO:1902580 180 0.027
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.027
double strand break repair via nonhomologous end joining GO:0006303 5 0.027
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.026
regionalization GO:0003002 416 0.026
regulation of catalytic activity GO:0050790 185 0.026
cellular ketone metabolic process GO:0042180 24 0.026
dna packaging GO:0006323 91 0.026
positive regulation of protein modification process GO:0031401 58 0.025
cellular component maintenance GO:0043954 23 0.025
posttranscriptional regulation of gene expression GO:0010608 145 0.025
endocytosis GO:0006897 310 0.024
positive regulation of cellular component organization GO:0051130 156 0.024
extracellular structure organization GO:0043062 46 0.024
cellular protein catabolic process GO:0044257 83 0.023
methylation GO:0032259 47 0.023
proteolysis GO:0006508 192 0.023
camera type eye development GO:0043010 4 0.023
regulation of reproductive process GO:2000241 54 0.022
chromatin modification GO:0016568 147 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.021
leg disc development GO:0035218 92 0.021
positive regulation of macromolecule metabolic process GO:0010604 405 0.021
post embryonic appendage morphogenesis GO:0035120 385 0.021
cytokinesis GO:0000910 90 0.021
regulation of gtp catabolic process GO:0033124 44 0.020
positive regulation of nucleotide metabolic process GO:0045981 55 0.020
dna replication GO:0006260 48 0.020
mrna metabolic process GO:0016071 124 0.020
establishment or maintenance of cell polarity GO:0007163 167 0.020
purine nucleoside triphosphate metabolic process GO:0009144 119 0.020
mitotic g2 m transition checkpoint GO:0044818 70 0.020
sensory organ morphogenesis GO:0090596 260 0.019
cell motility GO:0048870 251 0.019
leg disc morphogenesis GO:0007478 80 0.019
positive regulation of ras gtpase activity GO:0032320 36 0.019
response to organic substance GO:0010033 284 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
ribonucleoside monophosphate catabolic process GO:0009158 39 0.019
homeostatic process GO:0042592 199 0.019
response to abiotic stimulus GO:0009628 341 0.018
dna methylation GO:0006306 4 0.018
larval development GO:0002164 104 0.018
establishment of protein localization GO:0045184 163 0.018
cellular protein complex assembly GO:0043623 71 0.018
modification dependent macromolecule catabolic process GO:0043632 79 0.018
gene silencing by rna GO:0031047 57 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.018
regulation of cellular amine metabolic process GO:0033238 3 0.018
snrna metabolic process GO:0016073 14 0.017
posttranscriptional gene silencing GO:0016441 46 0.017
negative regulation of cellular component organization GO:0051129 108 0.017
macromolecule methylation GO:0043414 45 0.017
columnar cuboidal epithelial cell development GO:0002066 249 0.017
histone methylation GO:0016571 40 0.017
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.017
anterior posterior axis specification embryo GO:0008595 103 0.017
positive regulation of cellular component biogenesis GO:0044089 80 0.016
tripartite regional subdivision GO:0007351 103 0.016
spindle assembly involved in mitosis GO:0090307 50 0.016
double strand break repair GO:0006302 26 0.016
spindle organization GO:0007051 253 0.016
cell cycle phase transition GO:0044770 140 0.016
mrna processing GO:0006397 104 0.015
positive regulation of protein metabolic process GO:0051247 128 0.015
regulation of gtpase activity GO:0043087 44 0.015
organelle assembly GO:0070925 198 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
positive regulation of response to stimulus GO:0048584 323 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
stem cell maintenance GO:0019827 67 0.015
cellular component assembly involved in morphogenesis GO:0010927 151 0.015
positive regulation of cell communication GO:0010647 250 0.015
snrna processing GO:0016180 14 0.015
rna interference GO:0016246 27 0.014
appendage morphogenesis GO:0035107 397 0.014
meiotic cell cycle GO:0051321 171 0.014
regulation of cell cycle process GO:0010564 181 0.014
positive regulation of phosphate metabolic process GO:0045937 139 0.014
protein complex assembly GO:0006461 200 0.014
sex differentiation GO:0007548 81 0.014
regulation of nucleoside metabolic process GO:0009118 50 0.014
positive regulation of gtp catabolic process GO:0033126 43 0.014
spermatogenesis GO:0007283 200 0.014
regulation of protein catabolic process GO:0042176 55 0.013
neuron recognition GO:0008038 101 0.013
covalent chromatin modification GO:0016569 106 0.013
dorsal ventral pattern formation GO:0009953 133 0.013
protein alkylation GO:0008213 43 0.013
spindle assembly GO:0051225 80 0.013
gtp metabolic process GO:0046039 72 0.013
regulation of transport GO:0051049 181 0.013
establishment of localization in cell GO:0051649 402 0.013
enzyme linked receptor protein signaling pathway GO:0007167 179 0.013
stem cell development GO:0048864 79 0.012
cellular response to organic substance GO:0071310 132 0.012
macromolecular complex assembly GO:0065003 256 0.012
histone exchange GO:0043486 21 0.012
axon guidance GO:0007411 233 0.012
extracellular matrix organization GO:0030198 32 0.012
rna processing GO:0006396 147 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
regulation of cell differentiation GO:0045595 302 0.011
dorsal appendage formation GO:0046843 47 0.011
rna 3 end processing GO:0031123 45 0.011
dendrite morphogenesis GO:0048813 199 0.011
organelle fission GO:0048285 340 0.011
single organism behavior GO:0044708 391 0.011
rho protein signal transduction GO:0007266 14 0.011
defense response to other organism GO:0098542 225 0.011
positive regulation of nucleotide catabolic process GO:0030813 46 0.010
dna methylation or demethylation GO:0044728 4 0.010
negative regulation of organelle organization GO:0010639 56 0.010
rna splicing via transesterification reactions GO:0000375 73 0.010
regulation of cell maturation GO:1903429 27 0.010
negative regulation of cell cycle GO:0045786 116 0.010
ncrna 3 end processing GO:0043628 17 0.010

Hira disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org