Drosophila melanogaster

24 known processes

heix (Dmel_CG5876)

heixuedian

(Aliases: l(2)35Fc,Dmel\CG5876,124/1,ipa-6d,CG5876,BG:DS02740.7,l(2)k12401)

heix biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
glycoprotein biosynthetic process GO:0009101 41 0.333
immune system process GO:0002376 347 0.259
hemocyte differentiation GO:0042386 38 0.257
cellular response to starvation GO:0009267 61 0.246
oligosaccharide biosynthetic process GO:0009312 10 0.230
vesicle mediated transport GO:0016192 381 0.214
axon guidance GO:0007411 233 0.195
epithelial cell development GO:0002064 274 0.186
regulation of immune system process GO:0002682 176 0.172
taxis GO:0042330 304 0.163
columnar cuboidal epithelial cell development GO:0002066 249 0.159
regulation of hemocyte differentiation GO:0045610 22 0.154
carbohydrate derivative biosynthetic process GO:1901137 85 0.134
wing disc morphogenesis GO:0007472 344 0.129
single organism biosynthetic process GO:0044711 206 0.104
neuron projection guidance GO:0097485 241 0.100
axon development GO:0061564 297 0.097
response to organic substance GO:0010033 284 0.084
photoreceptor cell differentiation GO:0046530 170 0.082
chemotaxis GO:0006935 249 0.080
proteoglycan biosynthetic process GO:0030166 10 0.080
cellular response to extracellular stimulus GO:0031668 64 0.079
epithelial cell differentiation GO:0030855 322 0.079
regulation of multicellular organismal development GO:2000026 414 0.072
cellular response to nutrient levels GO:0031669 62 0.072
embryonic morphogenesis GO:0048598 206 0.068
imaginal disc derived wing morphogenesis GO:0007476 337 0.068
ion transmembrane transport GO:0034220 122 0.066
compound eye photoreceptor cell differentiation GO:0001751 140 0.065
homeostatic process GO:0042592 199 0.064
epithelial cell migration GO:0010631 148 0.062
secretion GO:0046903 109 0.062
ovarian follicle cell development GO:0030707 248 0.060
cell proliferation GO:0008283 299 0.060
carbohydrate metabolic process GO:0005975 82 0.060
endomembrane system organization GO:0010256 119 0.059
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.059
regionalization GO:0003002 416 0.059
endocytosis GO:0006897 310 0.058
organonitrogen compound biosynthetic process GO:1901566 117 0.057
ameboidal type cell migration GO:0001667 151 0.057
aminoglycan metabolic process GO:0006022 18 0.054
axonogenesis GO:0007409 290 0.054
protein modification process GO:0036211 438 0.054
stem cell differentiation GO:0048863 117 0.052
eye photoreceptor cell fate commitment GO:0042706 37 0.052
epithelium migration GO:0090132 148 0.051
organic acid metabolic process GO:0006082 103 0.051
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.051
regulation of cell differentiation GO:0045595 302 0.050
carbohydrate derivative metabolic process GO:1901135 217 0.050
transcription from rna polymerase ii promoter GO:0006366 368 0.048
metal ion homeostasis GO:0055065 44 0.048
single organism behavior GO:0044708 391 0.048
regulation of transport GO:0051049 181 0.047
appendage morphogenesis GO:0035107 397 0.046
ion transport GO:0006811 145 0.045
neuron fate commitment GO:0048663 50 0.044
single organism carbohydrate metabolic process GO:0044723 72 0.044
response to alcohol GO:0097305 95 0.044
response to starvation GO:0042594 97 0.044
transmembrane transport GO:0055085 139 0.044
photoreceptor cell fate commitment GO:0046552 41 0.043
post embryonic appendage morphogenesis GO:0035120 385 0.043
tissue migration GO:0090130 155 0.042
regulation of localization GO:0032879 275 0.042
response to oxygen containing compound GO:1901700 200 0.042
muscle structure development GO:0061061 224 0.041
peptide metabolic process GO:0006518 80 0.041
positive regulation of signal transduction GO:0009967 223 0.040
ovarian follicle cell migration GO:0007297 121 0.040
phagocytosis GO:0006909 215 0.039
organonitrogen compound metabolic process GO:1901564 318 0.039
glycoprotein metabolic process GO:0009100 41 0.038
growth GO:0040007 359 0.038
digestive tract development GO:0048565 149 0.038
positive regulation of cell motility GO:2000147 3 0.038
chemical homeostasis GO:0048878 92 0.038
eye photoreceptor cell differentiation GO:0001754 145 0.037
behavioral response to ethanol GO:0048149 49 0.037
organic substance transport GO:0071702 257 0.037
negative regulation of signal transduction GO:0009968 206 0.037
positive regulation of response to stimulus GO:0048584 323 0.037
immune response GO:0006955 246 0.037
regulation of cellular component biogenesis GO:0044087 201 0.036
g protein coupled receptor signaling pathway GO:0007186 136 0.035
small molecule metabolic process GO:0044281 305 0.035
immune effector process GO:0002252 98 0.034
response to glucose GO:0009749 2 0.034
regulation of immune response GO:0050776 118 0.034
mating behavior GO:0007617 106 0.034
negative regulation of gene expression GO:0010629 387 0.033
response to organic cyclic compound GO:0014070 89 0.033
programmed cell death GO:0012501 257 0.033
transition metal ion homeostasis GO:0055076 17 0.033
positive regulation of secretion GO:0051047 22 0.033
sensory organ morphogenesis GO:0090596 260 0.033
negative regulation of biosynthetic process GO:0009890 277 0.033
apoptotic process GO:0006915 159 0.032
adult behavior GO:0030534 137 0.032
purine containing compound metabolic process GO:0072521 155 0.032
heparan sulfate proteoglycan metabolic process GO:0030201 10 0.032
localization of cell GO:0051674 257 0.031
cell migration GO:0016477 238 0.031
regulation of anatomical structure morphogenesis GO:0022603 242 0.030
negative regulation of multicellular organismal process GO:0051241 142 0.030
catabolic process GO:0009056 409 0.030
regulation of cell cycle GO:0051726 291 0.030
negative regulation of response to stimulus GO:0048585 258 0.030
eye development GO:0001654 323 0.030
positive regulation of cell communication GO:0010647 250 0.030
response to monosaccharide GO:0034284 4 0.029
cell death GO:0008219 279 0.029
regulation of autophagy GO:0010506 62 0.029
neuron recognition GO:0008038 101 0.029
compound eye morphogenesis GO:0001745 249 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.028
compound eye development GO:0048749 307 0.028
cellular response to carbohydrate stimulus GO:0071322 4 0.027
regulation of cell growth GO:0001558 43 0.027
regulation of epithelial cell proliferation GO:0050678 4 0.027
multicellular organismal aging GO:0010259 140 0.027
border follicle cell migration GO:0007298 113 0.027
response to nutrient levels GO:0031667 114 0.027
single organism intracellular transport GO:1902582 207 0.027
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.027
membrane organization GO:0061024 112 0.027
response to lipopolysaccharide GO:0032496 4 0.027
death GO:0016265 284 0.027
imaginal disc derived appendage development GO:0048737 399 0.027
inositol lipid mediated signaling GO:0048017 4 0.026
regulation of programmed cell death GO:0043067 152 0.026
cellular response to organic substance GO:0071310 132 0.026
imaginal disc derived appendage morphogenesis GO:0035114 395 0.026
regulation of photoreceptor cell differentiation GO:0046532 34 0.025
mapk cascade GO:0000165 107 0.025
cellular response to monosaccharide stimulus GO:0071326 2 0.025
regulation of cell proliferation GO:0042127 163 0.025
regulation of vesicle mediated transport GO:0060627 59 0.024
open tracheal system development GO:0007424 204 0.024
secretion by cell GO:0032940 101 0.024
positive regulation of signaling GO:0023056 243 0.024
peptidyl amino acid modification GO:0018193 105 0.024
regulation of cellular component size GO:0032535 98 0.024
extracellular structure organization GO:0043062 46 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.024
establishment of localization in cell GO:0051649 402 0.024
regulation of cellular amine metabolic process GO:0033238 3 0.024
embryonic pattern specification GO:0009880 174 0.023
compound eye photoreceptor fate commitment GO:0001752 36 0.023
positive regulation of cell migration GO:0030335 2 0.023
protein transport GO:0015031 155 0.023
regulation of catalytic activity GO:0050790 185 0.023
organic substance catabolic process GO:1901575 308 0.023
digestive system development GO:0055123 149 0.022
cell motility GO:0048870 251 0.022
regulation of phosphate metabolic process GO:0019220 210 0.022
cellular metal ion homeostasis GO:0006875 31 0.022
hindgut development GO:0061525 58 0.022
salivary gland development GO:0007431 162 0.022
cellular homeostasis GO:0019725 80 0.022
cellular chemical homeostasis GO:0055082 40 0.021
response to biotic stimulus GO:0009607 294 0.021
aminoglycan biosynthetic process GO:0006023 11 0.021
heart development GO:0007507 82 0.021
central nervous system development GO:0007417 201 0.021
gland morphogenesis GO:0022612 145 0.021
nitrogen compound transport GO:0071705 85 0.021
salivary gland morphogenesis GO:0007435 145 0.021
glycosaminoglycan biosynthetic process GO:0006024 7 0.021
proteoglycan metabolic process GO:0006029 10 0.021
macromolecule catabolic process GO:0009057 161 0.021
response to extracellular stimulus GO:0009991 116 0.020
divalent inorganic cation transport GO:0072511 30 0.020
defense response GO:0006952 300 0.020
endosomal transport GO:0016197 44 0.020
lipid metabolic process GO:0006629 121 0.020
atp metabolic process GO:0046034 49 0.020
protein glycosylation GO:0006486 32 0.020
metal ion transport GO:0030001 74 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.020
vesicle organization GO:0016050 44 0.020
muscle organ development GO:0007517 127 0.020
locomotory behavior GO:0007626 176 0.020
regulation of anatomical structure size GO:0090066 163 0.020
negative regulation of developmental process GO:0051093 201 0.019
lateral inhibition GO:0046331 206 0.019
negative regulation of growth GO:0045926 84 0.019
digestive tract morphogenesis GO:0048546 127 0.019
establishment of protein localization GO:0045184 163 0.019
response to other organism GO:0051707 293 0.019
regulation of organ morphogenesis GO:2000027 78 0.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.019
inorganic ion transmembrane transport GO:0098660 73 0.019
regulation of notch signaling pathway GO:0008593 100 0.018
cellular protein modification process GO:0006464 438 0.018
terminal region determination GO:0007362 25 0.018
cellular response to external stimulus GO:0071496 66 0.018
cell growth GO:0016049 108 0.018
carbohydrate biosynthetic process GO:0016051 17 0.018
intracellular signal transduction GO:0035556 300 0.018
positive regulation of immune response GO:0050778 63 0.018
regulation of phosphorus metabolic process GO:0051174 210 0.018
cell maturation GO:0048469 144 0.018
regulation of stress activated mapk cascade GO:0032872 41 0.017
imaginal disc derived wing vein specification GO:0007474 48 0.017
cellular response to hexose stimulus GO:0071331 1 0.017
forebrain development GO:0030900 2 0.017
response to hexose GO:0009746 3 0.017
ribose phosphate metabolic process GO:0019693 145 0.017
tissue morphogenesis GO:0048729 297 0.017
dorsal ventral pattern formation GO:0009953 133 0.017
response to external biotic stimulus GO:0043207 293 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
purine nucleoside catabolic process GO:0006152 112 0.017
regulation of apoptotic process GO:0042981 130 0.017
eye morphogenesis GO:0048592 260 0.016
determination of adult lifespan GO:0008340 137 0.016
positive regulation of catabolic process GO:0009896 105 0.016
intracellular protein transport GO:0006886 104 0.016
chondroitin sulfate proteoglycan metabolic process GO:0050654 3 0.016
anterior posterior pattern specification GO:0009952 136 0.016
nucleoside catabolic process GO:0009164 112 0.016
negative regulation of intracellular signal transduction GO:1902532 57 0.016
organic cyclic compound catabolic process GO:1901361 168 0.016
positive regulation of transport GO:0051050 92 0.016
negative regulation of signaling GO:0023057 219 0.016
regulation of hormone levels GO:0010817 40 0.016
innate immune response GO:0045087 144 0.016
amine metabolic process GO:0009308 12 0.016
macromolecule glycosylation GO:0043413 32 0.015
exocrine system development GO:0035272 162 0.015
development of primary female sexual characteristics GO:0046545 12 0.015
bmp signaling pathway GO:0030509 27 0.015
purine nucleoside metabolic process GO:0042278 127 0.015
protein localization GO:0008104 284 0.015
regulation of behavior GO:0050795 75 0.015
blastoderm segmentation GO:0007350 159 0.015
negative regulation of cell communication GO:0010648 223 0.015
pattern recognition receptor signaling pathway GO:0002221 2 0.015
instar larval development GO:0002168 55 0.015
gland development GO:0048732 191 0.015
cellular nitrogen compound catabolic process GO:0044270 165 0.015
multi organism behavior GO:0051705 175 0.015
purine ribonucleoside catabolic process GO:0046130 112 0.015
cellular catabolic process GO:0044248 372 0.015
extracellular matrix organization GO:0030198 32 0.015
skeletal muscle fiber development GO:0048741 3 0.015
reproductive behavior GO:0019098 122 0.015
positive regulation of cell death GO:0010942 69 0.014
purine ribonucleotide metabolic process GO:0009150 145 0.014
r7 cell fate commitment GO:0007465 12 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
cellular macromolecule localization GO:0070727 220 0.014
response to decreased oxygen levels GO:0036293 58 0.014
establishment or maintenance of cell polarity GO:0007163 167 0.014
cellular response to organic cyclic compound GO:0071407 32 0.014
regulation of lipid metabolic process GO:0019216 15 0.014
hemopoiesis GO:0030097 46 0.014
extrinsic apoptotic signaling pathway GO:0097191 1 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
positive regulation of mapk cascade GO:0043410 63 0.014
cation transport GO:0006812 110 0.014
phosphatidylinositol mediated signaling GO:0048015 4 0.014
organelle localization GO:0051640 148 0.014
positive regulation of molecular function GO:0044093 136 0.014
appendage development GO:0048736 401 0.014
single organism catabolic process GO:0044712 228 0.014
heterocycle catabolic process GO:0046700 166 0.014
notch signaling pathway GO:0007219 120 0.014
positive regulation of lipid metabolic process GO:0045834 4 0.014
regulation of molecular function GO:0065009 217 0.013
organic hydroxy compound metabolic process GO:1901615 83 0.013
regulation of jnk cascade GO:0046328 40 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.013
humoral immune response GO:0006959 117 0.013
photoreceptor cell development GO:0042461 96 0.013
anterior posterior axis specification embryo GO:0008595 103 0.013
regulation of catabolic process GO:0009894 170 0.013
cellular response to chemical stimulus GO:0070887 199 0.013
neuromuscular junction development GO:0007528 149 0.013
oxoacid metabolic process GO:0043436 103 0.013
glycosaminoglycan metabolic process GO:0030203 11 0.013
aromatic compound catabolic process GO:0019439 166 0.013
jnk cascade GO:0007254 50 0.013
regulation of carbohydrate metabolic process GO:0006109 10 0.013
positive regulation of immune system process GO:0002684 68 0.013
muscle cell development GO:0055001 50 0.013
regulation of embryonic development GO:0045995 68 0.013
cellular ion homeostasis GO:0006873 39 0.013
nucleoside triphosphate metabolic process GO:0009141 120 0.013
positive regulation of nucleic acid templated transcription GO:1903508 266 0.013
response to sterol GO:0036314 34 0.013
regulation of mapk cascade GO:0043408 92 0.013
muscle fiber development GO:0048747 12 0.013
peptidyl threonine phosphorylation GO:0018107 2 0.012
autophagy GO:0006914 108 0.012
actin filament based process GO:0030029 220 0.012
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.012
ribonucleotide metabolic process GO:0009259 145 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
cell type specific apoptotic process GO:0097285 38 0.012
limb development GO:0060173 1 0.012
biological adhesion GO:0022610 138 0.012
striated muscle cell development GO:0055002 50 0.012
cell cycle arrest GO:0007050 4 0.012
cellular cation homeostasis GO:0030003 38 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.012
embryonic hindgut morphogenesis GO:0048619 48 0.012
negative regulation of notch signaling pathway GO:0045746 41 0.012
negative regulation of homeostatic process GO:0032845 2 0.012
courtship behavior GO:0007619 68 0.012
positive regulation of developmental process GO:0051094 143 0.012
peptidyl tyrosine phosphorylation GO:0018108 24 0.012
aging GO:0007568 143 0.012
r7 cell differentiation GO:0045466 43 0.012
r3 r4 cell differentiation GO:0048056 12 0.012
establishment of organelle localization GO:0051656 122 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
developmental growth GO:0048589 280 0.012
cation homeostasis GO:0055080 51 0.012
macromolecular complex assembly GO:0065003 256 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
tube morphogenesis GO:0035239 191 0.012
ras protein signal transduction GO:0007265 88 0.011
response to ethanol GO:0045471 59 0.011
negative regulation of cellular metabolic process GO:0031324 382 0.011
regulation of developmental growth GO:0048638 174 0.011
sulfur compound metabolic process GO:0006790 59 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
rna localization GO:0006403 115 0.011
regulation of growth GO:0040008 233 0.011
regulation of cellular localization GO:0060341 136 0.011
tube development GO:0035295 244 0.011
regulation of lamellipodium organization GO:1902743 15 0.011
negative regulation of cellular biosynthetic process GO:0031327 277 0.011
phosphate ion transport GO:0006817 4 0.011
cellular lipid metabolic process GO:0044255 83 0.011
eye photoreceptor cell development GO:0042462 81 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
stress activated protein kinase signaling cascade GO:0031098 55 0.011
regulation of cell development GO:0060284 215 0.011
regulation of actin filament based process GO:0032970 42 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
respiratory system development GO:0060541 213 0.011
mesoderm development GO:0007498 78 0.011
protein catabolic process GO:0030163 101 0.011
carboxylic acid metabolic process GO:0019752 92 0.011
regulation of cell death GO:0010941 173 0.011
mesenchymal cell differentiation GO:0048762 1 0.011
macroautophagy GO:0016236 42 0.010
transition metal ion transport GO:0000041 16 0.010
positive regulation of macromolecule metabolic process GO:0010604 405 0.010
positive regulation of cell differentiation GO:0045597 64 0.010
response to endogenous stimulus GO:0009719 119 0.010
cellular amine metabolic process GO:0044106 12 0.010
photoreceptor cell axon guidance GO:0072499 23 0.010
sensory perception GO:0007600 196 0.010
intracellular transport GO:0046907 228 0.010
small gtpase mediated signal transduction GO:0007264 88 0.010
maintenance of gastrointestinal epithelium GO:0030277 3 0.010
male gamete generation GO:0048232 201 0.010
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.010
purine nucleotide metabolic process GO:0006163 146 0.010
purine containing compound catabolic process GO:0072523 112 0.010
single organism cellular localization GO:1902580 180 0.010
camera type eye development GO:0043010 4 0.010
renal system development GO:0072001 72 0.010

heix disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
nervous system disease DOID:863 0 0.011