Drosophila melanogaster

81 known processes

bru (Dmel_CG2478)

brunelleschi

(Aliases: CG2478,Dmel\CG2478,38D.28)

bru biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic cytokinesis GO:0033206 33 0.999
meiosis ii GO:0007135 23 0.999
cytokinetic process GO:0032506 27 0.997
meiotic nuclear division GO:0007126 151 0.997
meiotic cell cycle GO:0051321 171 0.997
meiotic cell cycle process GO:1903046 132 0.995
meiosis i GO:0007127 59 0.986
cytoskeleton dependent cytokinesis GO:0061640 81 0.983
meiotic spindle organization GO:0000212 36 0.981
nuclear division GO:0000280 332 0.980
organelle fission GO:0048285 340 0.978
meiosis ii cytokinesis GO:0007111 11 0.975
meiosis i cytokinesis GO:0007110 12 0.963
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.944
regulation of protein complex disassembly GO:0043244 29 0.943
actomyosin contractile ring contraction GO:0000916 12 0.939
meiotic spindle stabilization GO:0043147 8 0.932
contractile ring contraction GO:0036213 12 0.922
regulation of spindle organization GO:0090224 17 0.881
spindle organization GO:0007051 253 0.866
cytokinesis GO:0000910 90 0.854
male meiosis GO:0007140 52 0.844
spindle stabilization GO:0043146 14 0.798
regulation of protein depolymerization GO:1901879 27 0.787
negative regulation of microtubule depolymerization GO:0007026 21 0.766
regulation of microtubule depolymerization GO:0031114 24 0.761
actomyosin contractile ring assembly GO:0000915 10 0.754
negative regulation of protein complex disassembly GO:0043242 23 0.754
negative regulation of protein depolymerization GO:1901880 23 0.752
microtubule depolymerization GO:0007019 25 0.718
male meiosis cytokinesis GO:0007112 26 0.707
cell division GO:0051301 248 0.703
regulation of microtubule cytoskeleton organization GO:0070507 41 0.702
actomyosin contractile ring organization GO:0044837 10 0.636
protein complex disassembly GO:0043241 36 0.617
protein depolymerization GO:0051261 31 0.560
assembly of actomyosin apparatus involved in cytokinesis GO:0000912 11 0.529
negative regulation of cytoskeleton organization GO:0051494 30 0.502
regulation of cell cycle process GO:0010564 181 0.485
regulation of microtubule based process GO:0032886 49 0.480
microtubule polymerization or depolymerization GO:0031109 39 0.478
actomyosin structure organization GO:0031032 56 0.437
regulation of cytoskeleton organization GO:0051493 89 0.432
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.398
negative regulation of cellular component organization GO:0051129 108 0.356
spermatocyte division GO:0048137 13 0.281
regulation of cell cycle GO:0051726 291 0.266
cellular protein complex disassembly GO:0043624 35 0.261
cellular component disassembly GO:0022411 46 0.231
male meiosis chromosome segregation GO:0007060 10 0.205
spindle assembly GO:0051225 80 0.193
macromolecular complex assembly GO:0065003 256 0.188
regulation of organelle organization GO:0033043 196 0.182
meiotic chromosome segregation GO:0045132 59 0.152
organelle assembly GO:0070925 198 0.117
macromolecular complex disassembly GO:0032984 37 0.113
chromosome segregation GO:0007059 157 0.101
protein complex assembly GO:0006461 200 0.083
protein complex biogenesis GO:0070271 201 0.078
spermatogenesis GO:0007283 200 0.075
actin cytoskeleton organization GO:0030036 206 0.062
actin filament based process GO:0030029 220 0.059
imaginal disc derived appendage development GO:0048737 399 0.057
appendage morphogenesis GO:0035107 397 0.055
endomembrane system organization GO:0010256 119 0.051
gland morphogenesis GO:0022612 145 0.050
sphingolipid metabolic process GO:0006665 19 0.047
positive regulation of macromolecule metabolic process GO:0010604 405 0.046
organonitrogen compound metabolic process GO:1901564 318 0.043
negative regulation of organelle organization GO:0010639 56 0.042
imaginal disc derived appendage morphogenesis GO:0035114 395 0.041
vesicle mediated transport GO:0016192 381 0.040
response to abiotic stimulus GO:0009628 341 0.039
positive regulation of rna metabolic process GO:0051254 271 0.039
wing disc morphogenesis GO:0007472 344 0.038
membrane organization GO:0061024 112 0.037
regionalization GO:0003002 416 0.036
synaptic transmission GO:0007268 288 0.036
small molecule metabolic process GO:0044281 305 0.035
male gamete generation GO:0048232 201 0.035
catabolic process GO:0009056 409 0.035
phagocytosis GO:0006909 215 0.034
cell motility GO:0048870 251 0.033
embryonic axis specification GO:0000578 107 0.033
establishment of localization in cell GO:0051649 402 0.033
nucleus organization GO:0006997 45 0.032
organic substance catabolic process GO:1901575 308 0.032
aromatic compound catabolic process GO:0019439 166 0.031
programmed cell death GO:0012501 257 0.031
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.029
positive regulation of cellular biosynthetic process GO:0031328 316 0.029
positive regulation of biosynthetic process GO:0009891 316 0.028
regulation of cell cycle phase transition GO:1901987 130 0.027
rac protein signal transduction GO:0016601 3 0.027
cell cell signaling involved in cell fate commitment GO:0045168 210 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.025
membrane lipid metabolic process GO:0006643 22 0.025
chromosome organization GO:0051276 360 0.025
organonitrogen compound biosynthetic process GO:1901566 117 0.025
segmentation GO:0035282 207 0.025
blastoderm segmentation GO:0007350 159 0.025
regulation of cellular component biogenesis GO:0044087 201 0.024
endocytosis GO:0006897 310 0.024
carbohydrate derivative metabolic process GO:1901135 217 0.024
mitotic spindle organization GO:0007052 220 0.024
mitotic cell cycle phase transition GO:0044772 138 0.024
histolysis GO:0007559 102 0.024
macromolecule catabolic process GO:0009057 161 0.024
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.024
male meiosis i GO:0007141 9 0.023
maintenance of protein location GO:0045185 28 0.023
body morphogenesis GO:0010171 2 0.022
regulation of cellular amine metabolic process GO:0033238 3 0.022
mesodermal cell migration GO:0008078 7 0.022
regulation of synapse structure and activity GO:0050803 128 0.022
salivary gland development GO:0007431 162 0.022
nucleobase containing small molecule metabolic process GO:0055086 174 0.022
regulation of developmental growth GO:0048638 174 0.022
eye morphogenesis GO:0048592 260 0.021
lateral inhibition GO:0046331 206 0.021
protein modification process GO:0036211 438 0.021
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.021
regulation of intracellular signal transduction GO:1902531 236 0.021
regulation of nervous system development GO:0051960 248 0.020
compound eye photoreceptor cell differentiation GO:0001751 140 0.020
photoreceptor cell differentiation GO:0046530 170 0.020
cell death GO:0008219 279 0.019
anterior posterior pattern specification GO:0009952 136 0.019
localization of cell GO:0051674 257 0.019
stem cell division GO:0017145 69 0.019
carboxylic acid metabolic process GO:0019752 92 0.019
rho protein signal transduction GO:0007266 14 0.019
photoreceptor cell development GO:0042461 96 0.019
regulation of synapse organization GO:0050807 110 0.018
cellular amine metabolic process GO:0044106 12 0.018
purine containing compound metabolic process GO:0072521 155 0.018
mrna processing GO:0006397 104 0.018
purine ribonucleotide catabolic process GO:0009154 109 0.018
salivary gland morphogenesis GO:0007435 145 0.018
imaginal disc derived wing morphogenesis GO:0007476 337 0.018
positive regulation of transcription dna templated GO:0045893 266 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.018
heterocycle catabolic process GO:0046700 166 0.018
regulation of mitotic cell cycle phase transition GO:1901990 130 0.018
cellular catabolic process GO:0044248 372 0.017
nucleobase containing compound catabolic process GO:0034655 165 0.017
oxoacid metabolic process GO:0043436 103 0.017
developmental growth GO:0048589 280 0.017
positive regulation of gene expression GO:0010628 290 0.017
eye photoreceptor cell development GO:0042462 81 0.017
ribonucleoside catabolic process GO:0042454 112 0.017
single organism biosynthetic process GO:0044711 206 0.017
embryonic pattern specification GO:0009880 174 0.017
compound eye photoreceptor development GO:0042051 78 0.017
positive regulation of nucleic acid templated transcription GO:1903508 266 0.016
modification dependent macromolecule catabolic process GO:0043632 79 0.016
cellular macromolecule localization GO:0070727 220 0.016
compound eye development GO:0048749 307 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
cellular macromolecule catabolic process GO:0044265 136 0.016
golgi organization GO:0007030 66 0.016
epithelial cell differentiation GO:0030855 322 0.016
positive regulation of rna biosynthetic process GO:1902680 266 0.016
regulation of programmed cell death GO:0043067 152 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
gland development GO:0048732 191 0.015
regulation of cell projection organization GO:0031344 92 0.015
tripartite regional subdivision GO:0007351 103 0.015
negative regulation of gene expression GO:0010629 387 0.015
regulation of cellular component size GO:0032535 98 0.015
very long chain fatty acid metabolic process GO:0000038 4 0.015
mitotic nuclear division GO:0007067 213 0.015
spindle assembly involved in mitosis GO:0090307 50 0.015
forebrain development GO:0030900 2 0.015
apoptotic process GO:0006915 159 0.015
maintenance of protein location in cell GO:0032507 26 0.015
synapse assembly GO:0007416 143 0.015
protein localization GO:0008104 284 0.014
amine metabolic process GO:0009308 12 0.014
cell cycle phase transition GO:0044770 140 0.014
maintenance of location in cell GO:0051651 28 0.014
multicellular organismal aging GO:0010259 140 0.014
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.014
tissue death GO:0016271 102 0.014
compound eye morphogenesis GO:0001745 249 0.014
exocrine system development GO:0035272 162 0.014
metal ion homeostasis GO:0055065 44 0.014
purine containing compound catabolic process GO:0072523 112 0.014
organophosphate metabolic process GO:0019637 195 0.014
pronuclear migration GO:0035046 4 0.014
cell migration GO:0016477 238 0.014
nuclear envelope organization GO:0006998 7 0.014
appendage development GO:0048736 401 0.013
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.013
anterior posterior axis specification embryo GO:0008595 103 0.013
positive regulation of multicellular organismal process GO:0051240 143 0.013
mitotic cytokinesis GO:0000281 50 0.013
sister chromatid segregation GO:0000819 92 0.013
cilium organization GO:0044782 41 0.013
adult behavior GO:0030534 137 0.013
regulation of multicellular organismal development GO:2000026 414 0.013
regulation of compound eye cone cell fate specification GO:0042682 4 0.013
negative regulation of mitotic cell cycle GO:0045930 109 0.013
nucleotide metabolic process GO:0009117 161 0.013
spermatid development GO:0007286 98 0.013
cellular ketone metabolic process GO:0042180 24 0.013
regulation of neuron projection development GO:0010975 69 0.013
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.012
telencephalon development GO:0021537 2 0.012
maintenance of location GO:0051235 73 0.012
plasma membrane organization GO:0007009 26 0.012
protein catabolic process GO:0030163 101 0.012
regulation of mitotic cell cycle GO:0007346 190 0.012
positive regulation of protein localization to plasma membrane GO:1903078 3 0.012
lipid metabolic process GO:0006629 121 0.012
neuroblast proliferation GO:0007405 74 0.012
intracellular signal transduction GO:0035556 300 0.012
pseudocleavage involved in syncytial blastoderm formation GO:0030589 9 0.012
cation homeostasis GO:0055080 51 0.012
cellular response to dna damage stimulus GO:0006974 223 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
regulation of mrna processing GO:0050684 71 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
spindle elongation GO:0051231 83 0.012
protein phosphorylation GO:0006468 169 0.012
regulation of organ morphogenesis GO:2000027 78 0.012
cell projection assembly GO:0030031 94 0.012
ras protein signal transduction GO:0007265 88 0.012
regulation of neuron differentiation GO:0045664 103 0.012
ribose phosphate metabolic process GO:0019693 145 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
regulation of catabolic process GO:0009894 170 0.011
germline ring canal formation GO:0030725 13 0.011
fatty acid elongation GO:0030497 3 0.011
germ line stem cell division GO:0042078 25 0.011
spindle assembly involved in male meiosis GO:0007053 5 0.011
alternative mrna splicing via spliceosome GO:0000380 60 0.011
regulation of anatomical structure size GO:0090066 163 0.011
snrna processing GO:0016180 14 0.011
transcription from rna polymerase ii promoter GO:0006366 368 0.011
connective tissue development GO:0061448 3 0.011
establishment of mitotic spindle orientation GO:0000132 13 0.011
carbohydrate metabolic process GO:0005975 82 0.011
cellular response to radiation GO:0071478 52 0.011
nucleoside catabolic process GO:0009164 112 0.011
single organism behavior GO:0044708 391 0.011
phosphorylation GO:0016310 294 0.010
single organism membrane organization GO:0044802 93 0.010
cellular protein modification process GO:0006464 438 0.010
purine ribonucleoside metabolic process GO:0046128 127 0.010
salivary gland histolysis GO:0035070 88 0.010
establishment of planar polarity GO:0001736 87 0.010
cytoplasmic transport GO:0016482 130 0.010
cellular macromolecular complex assembly GO:0034622 153 0.010
establishment or maintenance of cell polarity GO:0007163 167 0.010
chemotaxis GO:0006935 249 0.010
regulation of cell development GO:0060284 215 0.010
synaptic growth at neuromuscular junction GO:0051124 119 0.010
cellular amino acid metabolic process GO:0006520 61 0.010

bru disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
auditory system disease DOID:2742 0 0.026
autosomal dominant nonsyndromic deafness DOID:0050564 0 0.026
nonsyndromic deafness DOID:0050563 0 0.026
sensory system disease DOID:0050155 0 0.026
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026