Drosophila melanogaster

0 known processes

CHMP2B (Dmel_CG4618)

Charged multivesicular body protein 2b

(Aliases: CG4618,Dmel\CG4618,cg4618)

CHMP2B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vacuolar transport GO:0007034 13 0.813
endosomal transport GO:0016197 44 0.505
regulation of multi organism process GO:0043900 131 0.307
membrane budding GO:0006900 4 0.266
Human
single organism intracellular transport GO:1902582 207 0.257
vesicle organization GO:0016050 44 0.240
Human
establishment of localization in cell GO:0051649 402 0.235
regulation of erbb signaling pathway GO:1901184 42 0.218
interspecies interaction between organisms GO:0044419 16 0.217
Human
intracellular transport GO:0046907 228 0.213
negative regulation of erbb signaling pathway GO:1901185 29 0.206
endosome transport via multivesicular body sorting pathway GO:0032509 12 0.190
single organism cellular localization GO:1902580 180 0.169
single organism membrane budding GO:1902591 2 0.164
negative regulation of response to stimulus GO:0048585 258 0.162
cytoplasmic transport GO:0016482 130 0.151
catabolic process GO:0009056 409 0.149
protein localization GO:0008104 284 0.119
establishment or maintenance of cell polarity GO:0007163 167 0.114
growth GO:0040007 359 0.105
negative regulation of cell communication GO:0010648 223 0.098
regulation of localization GO:0032879 275 0.095
epithelial cell differentiation GO:0030855 322 0.092
vesicle mediated transport GO:0016192 381 0.088
Human
regulation of epithelial cell proliferation GO:0050678 4 0.087
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.086
positive regulation of multi organism process GO:0043902 40 0.083
negative regulation of signaling GO:0023057 219 0.083
organic substance transport GO:0071702 257 0.082
regulation of cellular localization GO:0060341 136 0.082
negative regulation of signal transduction GO:0009968 206 0.077
membrane fusion GO:0061025 42 0.072
establishment of protein localization GO:0045184 163 0.069
imaginal disc derived appendage development GO:0048737 399 0.069
cellular catabolic process GO:0044248 372 0.064
appendage development GO:0048736 401 0.064
endocytosis GO:0006897 310 0.064
secretion GO:0046903 109 0.063
protein transport GO:0015031 155 0.062
maintenance of location in cell GO:0051651 28 0.062
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 8 0.061
epithelial cell development GO:0002064 274 0.061
enzyme linked receptor protein signaling pathway GO:0007167 179 0.061
cellular macromolecule localization GO:0070727 220 0.059
regulation of cell proliferation GO:0042127 163 0.058
ovarian follicle cell development GO:0030707 248 0.056
modification dependent macromolecule catabolic process GO:0043632 79 0.055
response to starvation GO:0042594 97 0.053
single organism membrane organization GO:0044802 93 0.053
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 15 0.051
epidermal growth factor receptor signaling pathway GO:0007173 58 0.051
cell proliferation GO:0008283 299 0.050
humoral immune response GO:0006959 117 0.050
organonitrogen compound metabolic process GO:1901564 318 0.049
cellular protein localization GO:0034613 160 0.049
regulation of transport GO:0051049 181 0.048
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.047
phagocytosis GO:0006909 215 0.046
regulation of notch signaling pathway GO:0008593 100 0.045
appendage morphogenesis GO:0035107 397 0.044
dendrite morphogenesis GO:0048813 199 0.043
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.041
response to nutrient levels GO:0031667 114 0.041
purine nucleoside triphosphate metabolic process GO:0009144 119 0.040
nucleoside phosphate metabolic process GO:0006753 162 0.040
germarium derived egg chamber formation GO:0007293 101 0.039
organelle fission GO:0048285 340 0.039
autophagy GO:0006914 108 0.038
maintenance of location GO:0051235 73 0.037
post embryonic appendage morphogenesis GO:0035120 385 0.037
cell death GO:0008219 279 0.036
single organism catabolic process GO:0044712 228 0.036
positive regulation of transport GO:0051050 92 0.036
organic substance catabolic process GO:1901575 308 0.036
nucleoside triphosphate metabolic process GO:0009141 120 0.036
purine nucleotide metabolic process GO:0006163 146 0.035
macromolecule catabolic process GO:0009057 161 0.034
intracellular signal transduction GO:0035556 300 0.034
wing disc morphogenesis GO:0007472 344 0.033
negative regulation of notch signaling pathway GO:0045746 41 0.033
regulation of intracellular signal transduction GO:1902531 236 0.033
proteolysis GO:0006508 192 0.032
developmental growth GO:0048589 280 0.031
columnar cuboidal epithelial cell development GO:0002066 249 0.031
carbohydrate derivative metabolic process GO:1901135 217 0.030
body morphogenesis GO:0010171 2 0.030
organophosphate metabolic process GO:0019637 195 0.029
response to extracellular stimulus GO:0009991 116 0.029
regulation of growth GO:0040008 233 0.029
mitotic cell cycle phase transition GO:0044772 138 0.029
embryo development ending in birth or egg hatching GO:0009792 152 0.028
positive regulation of response to stimulus GO:0048584 323 0.028
cellular macromolecule catabolic process GO:0044265 136 0.028
secretion by cell GO:0032940 101 0.027
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.027
negative regulation of cellular metabolic process GO:0031324 382 0.027
regionalization GO:0003002 416 0.026
regulation of response to stress GO:0080134 200 0.026
morphogenesis of an epithelium GO:0002009 276 0.026
nucleoside triphosphate catabolic process GO:0009143 108 0.026
ribose phosphate metabolic process GO:0019693 145 0.025
ribonucleoside triphosphate metabolic process GO:0009199 119 0.025
protein complex biogenesis GO:0070271 201 0.025
symbiosis encompassing mutualism through parasitism GO:0044403 16 0.025
Human
purine ribonucleotide metabolic process GO:0009150 145 0.025
response to organic substance GO:0010033 284 0.025
notch signaling pathway GO:0007219 120 0.024
carbohydrate derivative catabolic process GO:1901136 118 0.024
nucleobase containing small molecule metabolic process GO:0055086 174 0.024
organic cyclic compound catabolic process GO:1901361 168 0.024
single organism biosynthetic process GO:0044711 206 0.024
establishment of protein localization to organelle GO:0072594 62 0.024
dendrite development GO:0016358 204 0.024
negative regulation of epithelial cell proliferation GO:0050680 4 0.024
regulation of cell cycle GO:0051726 291 0.023
regulation of secretion GO:0051046 44 0.023
localization of cell GO:0051674 257 0.022
organic hydroxy compound metabolic process GO:1901615 83 0.022
cellular protein catabolic process GO:0044257 83 0.022
negative regulation of gene expression GO:0010629 387 0.022
adult behavior GO:0030534 137 0.022
single organism behavior GO:0044708 391 0.022
nucleotide metabolic process GO:0009117 161 0.022
response to organophosphorus GO:0046683 2 0.021
cellular response to starvation GO:0009267 61 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.021
gland development GO:0048732 191 0.021
ribonucleoside metabolic process GO:0009119 127 0.021
transcription from rna polymerase ii promoter GO:0006366 368 0.021
ubiquitin dependent protein catabolic process GO:0006511 78 0.021
small molecule metabolic process GO:0044281 305 0.021
epidermis development GO:0008544 65 0.021
oxidoreduction coenzyme metabolic process GO:0006733 2 0.021
erbb signaling pathway GO:0038127 58 0.021
purine containing compound metabolic process GO:0072521 155 0.021
nucleoside metabolic process GO:0009116 127 0.020
death GO:0016265 284 0.019
nuclear division GO:0000280 332 0.019
purine nucleotide catabolic process GO:0006195 109 0.019
male gamete generation GO:0048232 201 0.019
regulation of cell cycle process GO:0010564 181 0.019
modification dependent protein catabolic process GO:0019941 78 0.019
protein localization to golgi apparatus GO:0034067 3 0.019
actin filament based process GO:0030029 220 0.019
purine ribonucleoside metabolic process GO:0046128 127 0.019
regulation of cell differentiation GO:0045595 302 0.019
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.019
intracellular protein transport GO:0006886 104 0.019
imaginal disc derived appendage morphogenesis GO:0035114 395 0.019
positive regulation of cellular component organization GO:0051130 156 0.019
biological adhesion GO:0022610 138 0.019
single organism membrane fusion GO:0044801 42 0.019
g protein coupled receptor signaling pathway GO:0007186 136 0.019
ribonucleotide metabolic process GO:0009259 145 0.018
muscle structure development GO:0061061 224 0.018
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.018
heterocycle catabolic process GO:0046700 166 0.018
epidermal cell differentiation GO:0009913 51 0.018
forebrain development GO:0030900 2 0.018
purine nucleoside metabolic process GO:0042278 127 0.018
antimicrobial humoral response GO:0019730 99 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.018
ovarian follicle cell stalk formation GO:0030713 17 0.017
segmentation GO:0035282 207 0.017
regulation of secretion by cell GO:1903530 39 0.017
aromatic compound catabolic process GO:0019439 166 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.017
response to external biotic stimulus GO:0043207 293 0.017
regulation of developmental growth GO:0048638 174 0.017
organelle fusion GO:0048284 46 0.017
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.017
cellular response to chemical stimulus GO:0070887 199 0.017
dorsal closure GO:0007391 79 0.017
cell division GO:0051301 248 0.016
negative regulation of cellular biosynthetic process GO:0031327 277 0.016
imaginal disc derived wing morphogenesis GO:0007476 337 0.016
cell migration GO:0016477 238 0.016
ribonucleoside catabolic process GO:0042454 112 0.016
exocytosis GO:0006887 28 0.016
programmed cell death GO:0012501 257 0.016
regulation of cell development GO:0060284 215 0.016
actin cytoskeleton organization GO:0030036 206 0.016
immune response GO:0006955 246 0.016
regulation of vesicle mediated transport GO:0060627 59 0.016
small gtpase mediated signal transduction GO:0007264 88 0.016
nucleoside catabolic process GO:0009164 112 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
mitotic nuclear division GO:0007067 213 0.016
cell adhesion GO:0007155 136 0.016
negative regulation of cell cycle phase transition GO:1901988 103 0.016
response to abiotic stimulus GO:0009628 341 0.016
organophosphate catabolic process GO:0046434 112 0.016
nucleobase containing compound catabolic process GO:0034655 165 0.015
maintenance of protein location in cell GO:0032507 26 0.015
negative regulation of growth GO:0045926 84 0.015
muscle organ development GO:0007517 127 0.015
developmental maturation GO:0021700 172 0.015
posttranscriptional regulation of gene expression GO:0010608 145 0.015
positive regulation of intracellular signal transduction GO:1902533 116 0.015
autophagic vacuole fusion GO:0000046 15 0.015
regulation of immune response GO:0050776 118 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.015
determination of adult lifespan GO:0008340 137 0.015
membrane organization GO:0061024 112 0.015
Human
negative regulation of cell proliferation GO:0008285 69 0.015
multicellular organismal aging GO:0010259 140 0.014
regulation of multicellular organismal development GO:2000026 414 0.014
regulation of nervous system development GO:0051960 248 0.014
protein catabolic process GO:0030163 101 0.014
negative regulation of mitotic cell cycle GO:0045930 109 0.014
defense response GO:0006952 300 0.014
meiotic cell cycle GO:0051321 171 0.014
gtp metabolic process GO:0046039 72 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
cell cycle phase transition GO:0044770 140 0.014
positive regulation of signaling GO:0023056 243 0.014
histolysis GO:0007559 102 0.014
positive regulation of cell communication GO:0010647 250 0.014
exocrine system development GO:0035272 162 0.014
purine nucleoside triphosphate catabolic process GO:0009146 108 0.014
spermatogenesis GO:0007283 200 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
negative regulation of rna metabolic process GO:0051253 251 0.013
cellular response to organic substance GO:0071310 132 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
regulation of neuron differentiation GO:0045664 103 0.013
head involution GO:0008258 35 0.013
cation transport GO:0006812 110 0.013
innate immune response GO:0045087 144 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
defense response to gram negative bacterium GO:0050829 94 0.013
positive regulation of exocytosis GO:0045921 4 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
jak stat cascade GO:0007259 49 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
salivary gland morphogenesis GO:0007435 145 0.013
positive regulation of secretion GO:0051047 22 0.013
gtp catabolic process GO:0006184 72 0.013
lipid metabolic process GO:0006629 121 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
tissue death GO:0016271 102 0.013
response to decreased oxygen levels GO:0036293 58 0.013
regulation of programmed cell death GO:0043067 152 0.013
cellular macromolecular complex assembly GO:0034622 153 0.013
regulation of antimicrobial peptide production GO:0002784 44 0.012
skin development GO:0043588 65 0.012
regulation of cell shape GO:0008360 113 0.012
phenol containing compound metabolic process GO:0018958 57 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.012
immune system process GO:0002376 347 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
eye development GO:0001654 323 0.012
nucleoside monophosphate metabolic process GO:0009123 52 0.012
negative regulation of nervous system development GO:0051961 92 0.012
ethanolamine containing compound metabolic process GO:0042439 4 0.012
regulation of cellular protein metabolic process GO:0032268 243 0.012
cytoskeleton dependent intracellular transport GO:0030705 44 0.012
endomembrane system organization GO:0010256 119 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.012
regulation of defense response GO:0031347 102 0.012
negative regulation of cell cycle GO:0045786 116 0.012
guanosine containing compound catabolic process GO:1901069 74 0.012
response to other organism GO:0051707 293 0.012
synapse assembly GO:0007416 143 0.012
mrna processing GO:0006397 104 0.012
cell motility GO:0048870 251 0.012
cell maturation GO:0048469 144 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
taxis GO:0042330 304 0.012
cellular protein modification process GO:0006464 438 0.011
negative regulation of developmental process GO:0051093 201 0.011
positive regulation of signal transduction GO:0009967 223 0.011
negative regulation of biosynthetic process GO:0009890 277 0.011
eye morphogenesis GO:0048592 260 0.011
apoptotic process GO:0006915 159 0.011
regulation of catalytic activity GO:0050790 185 0.011
regulation of mrna metabolic process GO:1903311 72 0.011
protein targeting GO:0006605 64 0.011
embryonic pattern specification GO:0009880 174 0.011
positive regulation of tor signaling GO:0032008 13 0.011
regulation of neurogenesis GO:0050767 158 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
regulation of antimicrobial humoral response GO:0002759 50 0.011
ribonucleoside triphosphate catabolic process GO:0009203 108 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
cellular response to extracellular stimulus GO:0031668 64 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
regulation of nucleotide metabolic process GO:0006140 62 0.011
camera type eye development GO:0043010 4 0.011
anterior posterior axis specification GO:0009948 109 0.011
response to biotic stimulus GO:0009607 294 0.011
cellular response to dna damage stimulus GO:0006974 223 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
nucleotide catabolic process GO:0009166 109 0.011
proteasomal protein catabolic process GO:0010498 59 0.011
response to bacterium GO:0009617 198 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
positive regulation of biosynthetic process GO:0009891 316 0.011
microtubule based transport GO:0010970 42 0.011
photoreceptor cell differentiation GO:0046530 170 0.011
amine metabolic process GO:0009308 12 0.011
positive regulation of gene expression GO:0010628 290 0.011
regulation of anatomical structure size GO:0090066 163 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
regulation of protein metabolic process GO:0051246 256 0.011
regulation of epidermal cell differentiation GO:0045604 3 0.010
purine ribonucleoside catabolic process GO:0046130 112 0.010
microtubule based movement GO:0007018 51 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.010
compound eye development GO:0048749 307 0.010
tissue morphogenesis GO:0048729 297 0.010
growth of symbiont involved in interaction with host GO:0044116 9 0.010
regulation of cell cycle phase transition GO:1901987 130 0.010
negative regulation of developmental growth GO:0048640 64 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.010
regulation of protein modification process GO:0031399 112 0.010
oxoacid metabolic process GO:0043436 103 0.010
salivary gland histolysis GO:0035070 88 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.010
guanosine containing compound metabolic process GO:1901068 74 0.010
negative regulation of intracellular signal transduction GO:1902532 57 0.010
positive regulation of molecular function GO:0044093 136 0.010
positive regulation of developmental process GO:0051094 143 0.010

CHMP2B disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
Human
nervous system disease DOID:863 0 0.012
Human