Drosophila melanogaster

115 known processes

NFAT (Dmel_CG11172)

NFAT homolog

(Aliases: NFAT5,EP1335,dNFAT,MESR1,Dmel\CG11172,CG11172,NF-AT5)

NFAT biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synapse organization GO:0050808 196 0.965
synaptic growth at neuromuscular junction GO:0051124 119 0.940
regulation of neurogenesis GO:0050767 158 0.931
synapse assembly GO:0007416 143 0.854
neuromuscular junction development GO:0007528 149 0.814
response to organic substance GO:0010033 284 0.745
regulation of nervous system development GO:0051960 248 0.722
negative regulation of signaling GO:0023057 219 0.708
negative regulation of cell communication GO:0010648 223 0.675
eye development GO:0001654 323 0.616
cellular response to chemical stimulus GO:0070887 199 0.611
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.584
regulation of neuron differentiation GO:0045664 103 0.567
regulation of multicellular organismal development GO:2000026 414 0.563
eye photoreceptor cell differentiation GO:0001754 145 0.562
response to abiotic stimulus GO:0009628 341 0.554
enzyme linked receptor protein signaling pathway GO:0007167 179 0.553
axon development GO:0061564 297 0.526
negative regulation of signal transduction GO:0009968 206 0.503
taxis GO:0042330 304 0.496
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.491
cell death GO:0008219 279 0.488
Mouse
negative regulation of response to stimulus GO:0048585 258 0.488
positive regulation of transcription dna templated GO:0045893 266 0.485
Human Mouse
eye morphogenesis GO:0048592 260 0.476
regulation of protein metabolic process GO:0051246 256 0.455
locomotory behavior GO:0007626 176 0.434
transcription from rna polymerase ii promoter GO:0006366 368 0.414
Human Mouse
intracellular signal transduction GO:0035556 300 0.399
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.382
Mouse
circulatory system development GO:0072359 82 0.379
Mouse
negative regulation of intracellular signal transduction GO:1902532 57 0.369
cardiovascular system development GO:0072358 82 0.365
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.359
Human Mouse
regulation of neuron projection development GO:0010975 69 0.348
regulation of cellular amino acid metabolic process GO:0006521 0 0.344
compound eye morphogenesis GO:0001745 249 0.343
regulation of cell cycle GO:0051726 291 0.338
regulation of cell development GO:0060284 215 0.328
regulation of cell differentiation GO:0045595 302 0.321
Mouse
axon guidance GO:0007411 233 0.319
regulation of cellular protein metabolic process GO:0032268 243 0.315
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.301
Human Mouse
regulation of synapse organization GO:0050807 110 0.298
epithelial cell differentiation GO:0030855 322 0.286
erbb signaling pathway GO:0038127 58 0.286
regulation of programmed cell death GO:0043067 152 0.283
Mouse
organelle fission GO:0048285 340 0.281
developmental growth GO:0048589 280 0.278
biological adhesion GO:0022610 138 0.268
positive regulation of synapse assembly GO:0051965 29 0.257
regulation of synapse structure and activity GO:0050803 128 0.253
regulation of cellular ketone metabolic process GO:0010565 3 0.246
regulation of molecular function GO:0065009 217 0.244
negative regulation of cellular metabolic process GO:0031324 382 0.243
Mouse
negative regulation of protein metabolic process GO:0051248 85 0.242
regulation of apoptotic process GO:0042981 130 0.238
Mouse
sensory organ morphogenesis GO:0090596 260 0.237
regulation of protein phosphorylation GO:0001932 64 0.235
catabolic process GO:0009056 409 0.231
neurological system process GO:0050877 358 0.229
immune response regulating signaling pathway GO:0002764 2 0.226
Human
negative regulation of erbb signaling pathway GO:1901185 29 0.224
regulation of intracellular signal transduction GO:1902531 236 0.221
death GO:0016265 284 0.215
Mouse
homeostatic process GO:0042592 199 0.213
regulation of protein kinase activity GO:0045859 51 0.210
regulation of response to stress GO:0080134 200 0.208
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.206
growth GO:0040007 359 0.206
chemotaxis GO:0006935 249 0.205
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.203
Mouse
macromolecule catabolic process GO:0009057 161 0.201
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.201
Mouse
larval development GO:0002164 104 0.200
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.198
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.198
Mouse
wnt signaling pathway GO:0016055 98 0.197
cellular response to organic substance GO:0071310 132 0.195
positive regulation of molecular function GO:0044093 136 0.191
protein phosphorylation GO:0006468 169 0.189
response to endogenous stimulus GO:0009719 119 0.188
positive regulation of rna biosynthetic process GO:1902680 266 0.186
Human Mouse
phosphorylation GO:0016310 294 0.184
regulation of cellular localization GO:0060341 136 0.184
axonogenesis GO:0007409 290 0.182
photoreceptor cell differentiation GO:0046530 170 0.180
organelle assembly GO:0070925 198 0.180
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.178
Mouse
positive regulation of signal transduction GO:0009967 223 0.178
Mouse
organic acid metabolic process GO:0006082 103 0.177
regulation of phosphate metabolic process GO:0019220 210 0.177
negative regulation of small gtpase mediated signal transduction GO:0051058 13 0.173
negative regulation of cell cycle GO:0045786 116 0.172
single organism cellular localization GO:1902580 180 0.172
compound eye photoreceptor cell differentiation GO:0001751 140 0.170
carboxylic acid metabolic process GO:0019752 92 0.170
regulation of cell death GO:0010941 173 0.169
Mouse
cellular catabolic process GO:0044248 372 0.168
positive regulation of developmental process GO:0051094 143 0.167
Mouse
cellular protein modification process GO:0006464 438 0.166
appendage morphogenesis GO:0035107 397 0.165
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.161
regulation of growth GO:0040008 233 0.159
small molecule metabolic process GO:0044281 305 0.159
circadian behavior GO:0048512 76 0.157
positive regulation of response to stimulus GO:0048584 323 0.156
Human Mouse
response to other organism GO:0051707 293 0.155
regulation of catalytic activity GO:0050790 185 0.153
protein modification process GO:0036211 438 0.153
regulation of localization GO:0032879 275 0.152
negative regulation of cell proliferation GO:0008285 69 0.152
immune response activating signal transduction GO:0002757 2 0.150
Human
regionalization GO:0003002 416 0.148
negative regulation of phosphorus metabolic process GO:0010563 45 0.148
brain development GO:0007420 120 0.148
positive regulation of response to external stimulus GO:0032103 44 0.144
regulation of synapse assembly GO:0051963 94 0.144
oxoacid metabolic process GO:0043436 103 0.142
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.139
Human Mouse
positive regulation of protein metabolic process GO:0051247 128 0.138
regulation of circadian rhythm GO:0042752 49 0.136
regulation of phosphorus metabolic process GO:0051174 210 0.132
regulation of photoreceptor cell differentiation GO:0046532 34 0.131
negative regulation of ras protein signal transduction GO:0046580 13 0.131
regulation of cellular component biogenesis GO:0044087 201 0.130
establishment of localization in cell GO:0051649 402 0.127
regulation of hydrolase activity GO:0051336 97 0.125
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 8 0.125
positive regulation of rna metabolic process GO:0051254 271 0.123
Human Mouse
response to external biotic stimulus GO:0043207 293 0.119
negative regulation of mitotic cell cycle GO:0045930 109 0.119
regulation of wnt signaling pathway GO:0030111 68 0.117
organic substance transport GO:0071702 257 0.117
negative regulation of molecular function GO:0044092 51 0.117
autophagy GO:0006914 108 0.115
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.115
regulation of developmental growth GO:0048638 174 0.113
positive regulation of macromolecule metabolic process GO:0010604 405 0.113
Human Mouse
regulation of organelle organization GO:0033043 196 0.112
secretion GO:0046903 109 0.112
positive regulation of cell differentiation GO:0045597 64 0.112
Mouse
negative regulation of biosynthetic process GO:0009890 277 0.112
Mouse
negative regulation of cellular protein metabolic process GO:0032269 85 0.112
positive regulation of phosphate metabolic process GO:0045937 139 0.112
positive regulation of nervous system development GO:0051962 69 0.110
organic substance catabolic process GO:1901575 308 0.108
peptidyl tyrosine phosphorylation GO:0018108 24 0.108
regulation of phosphorylation GO:0042325 147 0.108
vesicle mediated transport GO:0016192 381 0.107
apoptotic signaling pathway GO:0097190 27 0.106
Mouse
endocytosis GO:0006897 310 0.106
immune system process GO:0002376 347 0.104
Human Mouse
kidney development GO:0001822 3 0.104
positive regulation of neurogenesis GO:0050769 41 0.104
regulation of mitosis GO:0007088 56 0.104
peptidyl threonine phosphorylation GO:0018107 2 0.104
positive regulation of cellular amine metabolic process GO:0033240 0 0.102
mrna metabolic process GO:0016071 124 0.102
regulation of mitotic cell cycle GO:0007346 190 0.102
organonitrogen compound metabolic process GO:1901564 318 0.102
cellular ketone metabolic process GO:0042180 24 0.101
circadian rhythm GO:0007623 105 0.100
signal release GO:0023061 49 0.098
regulation of behavior GO:0050795 75 0.098
immune response GO:0006955 246 0.098
Human
regulation of anatomical structure morphogenesis GO:0022603 242 0.098
Mouse
negative regulation of gene expression GO:0010629 387 0.098
Mouse
establishment of tissue polarity GO:0007164 87 0.096
actin filament based process GO:0030029 220 0.094
peptidyl amino acid modification GO:0018193 105 0.094
photoreceptor cell axon guidance GO:0072499 23 0.092
cell motility GO:0048870 251 0.092
Human
negative regulation of phosphorylation GO:0042326 35 0.092
dorsal ventral pattern formation GO:0009953 133 0.092
positive regulation of cell migration GO:0030335 2 0.090
establishment or maintenance of cell polarity GO:0007163 167 0.090
cellular macromolecule catabolic process GO:0044265 136 0.089
response to extracellular stimulus GO:0009991 116 0.088
tissue morphogenesis GO:0048729 297 0.088
Mouse
nuclear import GO:0051170 51 0.087
positive regulation of cellular component organization GO:0051130 156 0.086
Mouse
cellular response to dna damage stimulus GO:0006974 223 0.083
regulation of mapk cascade GO:0043408 92 0.083
regulation of secretion by cell GO:1903530 39 0.083
neuroblast proliferation GO:0007405 74 0.083
positive regulation of autophagy GO:0010508 21 0.083
proteolysis GO:0006508 192 0.081
compound eye development GO:0048749 307 0.081
protein import GO:0017038 55 0.080
positive regulation of biosynthetic process GO:0009891 316 0.079
Human Mouse
positive regulation of multicellular organismal process GO:0051240 143 0.079
Mouse
imaginal disc pattern formation GO:0007447 91 0.079
heart process GO:0003015 37 0.078
regulation of protein modification process GO:0031399 112 0.078
regulation of r7 cell differentiation GO:0045676 15 0.078
appendage development GO:0048736 401 0.075
morphogenesis of a polarized epithelium GO:0001738 93 0.073
heart development GO:0007507 82 0.071
Mouse
response to light stimulus GO:0009416 124 0.071
Mouse
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.071
regulation of cellular response to stress GO:0080135 89 0.071
cellular response to growth factor stimulus GO:0071363 30 0.071
inositol lipid mediated signaling GO:0048017 4 0.071
phosphatidylinositol mediated signaling GO:0048015 4 0.071
response to oxidative stress GO:0006979 86 0.071
cellular protein localization GO:0034613 160 0.070
neuron projection guidance GO:0097485 241 0.069
programmed cell death GO:0012501 257 0.069
Mouse
locomotor rhythm GO:0045475 56 0.068
regulation of response to external stimulus GO:0032101 115 0.068
imaginal disc derived appendage morphogenesis GO:0035114 395 0.068
positive regulation of histone deacetylation GO:0031065 2 0.067
negative regulation of cellular component organization GO:0051129 108 0.066
enteroendocrine cell differentiation GO:0035883 1 0.066
positive regulation of transport GO:0051050 92 0.065
regulation of erbb signaling pathway GO:1901184 42 0.065
cellular response to endogenous stimulus GO:0071495 80 0.065
cell cycle checkpoint GO:0000075 95 0.064
negative regulation of transcription dna templated GO:0045892 237 0.064
Mouse
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.064
positive regulation of phosphorylation GO:0042327 87 0.063
imaginal disc derived appendage development GO:0048737 399 0.063
regulation of system process GO:0044057 36 0.063
Mouse
negative regulation of defense response GO:0031348 35 0.063
rhythmic behavior GO:0007622 76 0.063
response to organic cyclic compound GO:0014070 89 0.062
mitotic cell cycle checkpoint GO:0007093 88 0.062
establishment of protein localization to organelle GO:0072594 62 0.061
calcium ion transport GO:0006816 24 0.060
Mouse
posttranscriptional regulation of gene expression GO:0010608 145 0.060
single organism biosynthetic process GO:0044711 206 0.060
regulation of nurse cell apoptotic process GO:0045477 9 0.059
cellular response to oxygen containing compound GO:1901701 79 0.059
positive regulation of cell development GO:0010720 61 0.059
cytoplasmic transport GO:0016482 130 0.058
regulation of cellular amine metabolic process GO:0033238 3 0.058
single organism behavior GO:0044708 391 0.058
negative regulation of cell cycle process GO:0010948 109 0.058
mapk cascade GO:0000165 107 0.056
regulation of transport GO:0051049 181 0.055
regulation of immune response GO:0050776 118 0.055
Human
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.055
regulation of cytoplasmic transport GO:1903649 47 0.055
compound eye photoreceptor fate commitment GO:0001752 36 0.055
sex differentiation GO:0007548 81 0.055
response to biotic stimulus GO:0009607 294 0.055
negative regulation of rna metabolic process GO:0051253 251 0.055
Mouse
spindle organization GO:0007051 253 0.054
negative regulation of multicellular organismal process GO:0051241 142 0.054
cell cell adhesion GO:0098609 26 0.053
amine metabolic process GO:0009308 12 0.053
positive regulation of phosphorus metabolic process GO:0010562 139 0.052
cellular homeostasis GO:0019725 80 0.052
epidermal growth factor receptor signaling pathway GO:0007173 58 0.052
oocyte axis specification GO:0007309 108 0.052
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.052
positive regulation of macroautophagy GO:0016239 8 0.051
establishment of planar polarity GO:0001736 87 0.051
cellular response to lipopolysaccharide GO:0071222 3 0.050
regulation of axon extension involved in axon guidance GO:0048841 4 0.050
positive regulation of hydrolase activity GO:0051345 78 0.050
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.050
Human Mouse
reproductive structure development GO:0048608 74 0.050
regulation of immune system process GO:0002682 176 0.050
Human
cell growth GO:0016049 108 0.049
gene silencing GO:0016458 138 0.049
response to growth factor GO:0070848 31 0.049
post embryonic appendage morphogenesis GO:0035120 385 0.049
negative regulation of organelle organization GO:0010639 56 0.048
response to oxygen containing compound GO:1901700 200 0.048
regulation of epithelial cell differentiation GO:0030856 4 0.047
sensory organ boundary specification GO:0008052 22 0.047
cellular amino acid metabolic process GO:0006520 61 0.047
negative regulation of cellular biosynthetic process GO:0031327 277 0.047
Mouse
negative regulation of cell cell adhesion GO:0022408 8 0.046
cell cycle phase transition GO:0044770 140 0.046
Mouse
anatomical structure homeostasis GO:0060249 97 0.046
posttranscriptional gene silencing GO:0016441 46 0.046
phagocytosis GO:0006909 215 0.046
positive regulation of neuron projection development GO:0010976 14 0.045
positive regulation of intracellular signal transduction GO:1902533 116 0.045
rhythmic process GO:0048511 106 0.045
protein catabolic process GO:0030163 101 0.044
digestive tract development GO:0048565 149 0.044
cellular amine metabolic process GO:0044106 12 0.044
actin cytoskeleton organization GO:0030036 206 0.044
trunk segmentation GO:0035290 8 0.043
regulation of cell cycle phase transition GO:1901987 130 0.043
regulation of secretion GO:0051046 44 0.043
positive regulation of proteolysis GO:0045862 52 0.043
rna catabolic process GO:0006401 37 0.042
response to wounding GO:0009611 94 0.042
muscle structure development GO:0061061 224 0.042
Mouse
positive regulation of cell motility GO:2000147 3 0.042
extrinsic apoptotic signaling pathway GO:0097191 1 0.042
cellular response to hormone stimulus GO:0032870 44 0.041
nuclear division GO:0000280 332 0.041
cell maturation GO:0048469 144 0.041
regulation of intracellular transport GO:0032386 64 0.041
sensory perception of chemical stimulus GO:0007606 116 0.041
wing disc pattern formation GO:0035222 66 0.041
response to nutrient levels GO:0031667 114 0.040
embryo development ending in birth or egg hatching GO:0009792 152 0.040
response to temperature stimulus GO:0009266 106 0.040
energy derivation by oxidation of organic compounds GO:0015980 32 0.040
Mouse
regulation of neuroblast proliferation GO:1902692 34 0.040
r7 cell differentiation GO:0045466 43 0.040
signal transduction by phosphorylation GO:0023014 107 0.040
photoreceptor cell development GO:0042461 96 0.039
positive regulation of cell communication GO:0010647 250 0.039
Mouse
cell division GO:0051301 248 0.039
regulation of mitotic cell cycle phase transition GO:1901990 130 0.039
chaeta development GO:0022416 97 0.039
cellular response to insulin stimulus GO:0032869 28 0.038
macromolecular complex assembly GO:0065003 256 0.038
regulation of cell cell adhesion GO:0022407 21 0.038
organ growth GO:0035265 56 0.038
eye photoreceptor cell fate commitment GO:0042706 37 0.038
rna processing GO:0006396 147 0.038
regulation of stem cell proliferation GO:0072091 40 0.038
defense response to bacterium GO:0042742 178 0.038
regulation of defense response GO:0031347 102 0.037
positive regulation of apoptotic signaling pathway GO:2001235 4 0.037
Mouse
semaphorin plexin signaling pathway GO:0071526 4 0.037
regulation of carbohydrate metabolic process GO:0006109 10 0.037
regulation of catabolic process GO:0009894 170 0.036
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.036
eye photoreceptor cell development GO:0042462 81 0.036
photoreceptor cell fate commitment GO:0046552 41 0.036
morphogenesis of an epithelium GO:0002009 276 0.036
Mouse
learning or memory GO:0007611 141 0.036
negative regulation of developmental process GO:0051093 201 0.036
regulation of cell projection organization GO:0031344 92 0.036
digestive system development GO:0055123 149 0.036
dephosphorylation GO:0016311 51 0.036
renal system development GO:0072001 72 0.035
somatic muscle development GO:0007525 66 0.035
positive regulation of catalytic activity GO:0043085 118 0.035
intracellular transport GO:0046907 228 0.035
semaphorin plexin signaling pathway involved in regulation of photoreceptor cell axon guidance GO:2000305 2 0.035
circulatory system process GO:0003013 37 0.035
protein complex biogenesis GO:0070271 201 0.035
lipid metabolic process GO:0006629 121 0.035
purine nucleotide metabolic process GO:0006163 146 0.034
protein transport GO:0015031 155 0.034
regulation of cell migration GO:0030334 22 0.034
multicellular organismal reproductive behavior GO:0033057 110 0.034
regulation of proteolysis GO:0030162 87 0.034
sevenless signaling pathway GO:0045500 4 0.034
response to nitrogen compound GO:1901698 90 0.034
antimicrobial humoral response GO:0019730 99 0.034
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.034
intracellular protein transport GO:0006886 104 0.033
regulation of cellular component movement GO:0051270 42 0.033
protein localization GO:0008104 284 0.033
cellularization GO:0007349 90 0.033
negative regulation of phosphate metabolic process GO:0045936 45 0.033
oxidation reduction process GO:0055114 123 0.033
Mouse
detection of visible light GO:0009584 38 0.033
positive regulation of cellular biosynthetic process GO:0031328 316 0.033
Human Mouse
positive regulation of r7 cell differentiation GO:0045678 7 0.033
blood circulation GO:0008015 26 0.032
positive regulation of cell death GO:0010942 69 0.032
Mouse
protein processing GO:0016485 68 0.032
neuron fate commitment GO:0048663 50 0.032
positive regulation of catabolic process GO:0009896 105 0.032
organ formation GO:0048645 39 0.032
regulation of multi organism process GO:0043900 131 0.031
motor neuron axon guidance GO:0008045 58 0.031
embryonic development via the syncytial blastoderm GO:0001700 148 0.031
internal protein amino acid acetylation GO:0006475 38 0.031
reproductive system development GO:0061458 74 0.031
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.031
epithelial cell development GO:0002064 274 0.030
establishment of protein localization GO:0045184 163 0.030
positive regulation of protein phosphorylation GO:0001934 34 0.030
negative regulation of synapse assembly GO:0051964 39 0.030
chromosome segregation GO:0007059 157 0.030
development of primary sexual characteristics GO:0045137 50 0.030
protein localization to organelle GO:0033365 82 0.030
regulation of epithelial cell proliferation GO:0050678 4 0.029
organic cyclic compound catabolic process GO:1901361 168 0.029
nuclear transcribed mrna catabolic process GO:0000956 24 0.029
neuron death GO:0070997 27 0.029
synaptic transmission GO:0007268 288 0.029
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.029
peptidyl tyrosine modification GO:0018212 24 0.029
columnar cuboidal epithelial cell development GO:0002066 249 0.029
regulation of map kinase activity GO:0043405 17 0.029
larval midgut histolysis GO:0035069 22 0.029
signal transduction in response to dna damage GO:0042770 3 0.029
response to starvation GO:0042594 97 0.029
positive regulation of feeding behavior GO:2000253 8 0.029
gonad development GO:0008406 50 0.028
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.028
cardiac cell fate determination GO:0060913 3 0.028
negative regulation of nucleic acid templated transcription GO:1903507 240 0.028
Mouse
substrate adhesion dependent cell spreading GO:0034446 2 0.028
regulation of gene silencing GO:0060968 63 0.028
cellular response to starvation GO:0009267 61 0.028
anterior posterior axis specification embryo GO:0008595 103 0.028
detection of stimulus involved in sensory perception GO:0050906 92 0.028
positive regulation of nucleic acid templated transcription GO:1903508 266 0.028
Human Mouse
regulation of chromosome organization GO:0033044 64 0.028
negative regulation of cell differentiation GO:0045596 143 0.027
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.027
spinal cord development GO:0021510 1 0.027
regulation of organ morphogenesis GO:2000027 78 0.027
positive regulation of programmed cell death GO:0043068 62 0.027
Mouse
positive regulation of axon guidance GO:1902669 1 0.027
organonitrogen compound biosynthetic process GO:1901566 117 0.027
cell migration GO:0016477 238 0.026
Human
bmp signaling pathway GO:0030509 27 0.026
single organismal cell cell adhesion GO:0016337 45 0.026
generation of precursor metabolites and energy GO:0006091 42 0.026
Mouse
dna damage checkpoint GO:0000077 78 0.026
regulation of gene expression epigenetic GO:0040029 128 0.026
axis specification GO:0009798 167 0.026
maintenance of location GO:0051235 73 0.026
stem cell proliferation GO:0072089 88 0.026
cellular macromolecular complex assembly GO:0034622 153 0.026
male sex differentiation GO:0046661 25 0.026
neuron maturation GO:0042551 31 0.026
glandular epithelial cell differentiation GO:0002067 1 0.025
positive regulation of protein modification process GO:0031401 58 0.025
chemical homeostasis GO:0048878 92 0.025
mrna catabolic process GO:0006402 33 0.025
cell fate commitment involved in formation of primary germ layer GO:0060795 10 0.025
peripheral nervous system neuron development GO:0048935 8 0.025
single organism cell adhesion GO:0098602 47 0.025
cell fate specification GO:0001708 71 0.025
hematopoietic or lymphoid organ development GO:0048534 57 0.025
Mouse
protein targeting GO:0006605 64 0.025
sperm individualization GO:0007291 48 0.025
dorsal ventral axon guidance GO:0033563 2 0.025
central nervous system development GO:0007417 201 0.025
regulation of protein catabolic process GO:0042176 55 0.025
protein autophosphorylation GO:0046777 15 0.025
connective tissue development GO:0061448 3 0.024
response to lipid GO:0033993 38 0.024
cell adhesion GO:0007155 136 0.024
blastoderm segmentation GO:0007350 159 0.024
positive regulation of cellular protein metabolic process GO:0032270 118 0.024
forebrain development GO:0030900 2 0.024
positive regulation of apoptotic process GO:0043065 47 0.024
Mouse
single organism nuclear import GO:1902593 51 0.024
localization of cell GO:0051674 257 0.024
Human
axon extension involved in axon guidance GO:0048846 10 0.024
ion homeostasis GO:0050801 55 0.024
regulation of embryonic development GO:0045995 68 0.024
regulation of ras protein signal transduction GO:0046578 93 0.024
nephron development GO:0072006 3 0.023
erk1 and erk2 cascade GO:0070371 39 0.023
planar cell polarity pathway involved in axis elongation GO:0003402 3 0.023
protein targeting to nucleus GO:0044744 51 0.023
negative regulation of catalytic activity GO:0043086 42 0.023
innate immune response activating signal transduction GO:0002758 2 0.023
regulation of reproductive process GO:2000241 54 0.023
bmp signaling pathway involved in malpighian tubule cell chemotaxis GO:0061353 3 0.023
regulation of anatomical structure size GO:0090066 163 0.023
mesenchymal cell development GO:0014031 1 0.023
Mouse
heart contraction GO:0060047 26 0.023
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 4 0.023
negative regulation of epithelial cell proliferation GO:0050680 4 0.023
modification dependent protein catabolic process GO:0019941 78 0.023
ubiquitin dependent protein catabolic process GO:0006511 78 0.023
head development GO:0060322 135 0.023
single organism intracellular transport GO:1902582 207 0.022
regulation of neuron death GO:1901214 26 0.022
divalent metal ion transport GO:0070838 26 0.022
Mouse
stress activated protein kinase signaling cascade GO:0031098 55 0.022
pigmentation GO:0043473 75 0.022
regulation of transferase activity GO:0051338 58 0.022
cellular carbohydrate metabolic process GO:0044262 22 0.022
regulation of cellular response to growth factor stimulus GO:0090287 13 0.022
regulation of kinase activity GO:0043549 53 0.022
negative regulation of rna biosynthetic process GO:1902679 240 0.022
Mouse
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.022
protein modification by small protein removal GO:0070646 28 0.022
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 2 0.022
organophosphate metabolic process GO:0019637 195 0.022
cytokinesis GO:0000910 90 0.022
positive regulation of mapk cascade GO:0043410 63 0.021
cell cell signaling involved in cell fate commitment GO:0045168 210 0.021
segmentation GO:0035282 207 0.021
positive regulation of nurse cell apoptotic process GO:0045850 5 0.021
regulation of cell cycle process GO:0010564 181 0.021
peptidyl threonine modification GO:0018210 3 0.021
small gtpase mediated signal transduction GO:0007264 88 0.021
positive regulation of growth GO:0045927 75 0.021

NFAT disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.131
acquired metabolic disease DOID:0060158 0 0.131
disease of anatomical entity DOID:7 0 0.056
vascular disease DOID:178 0 0.056
cardiovascular system disease DOID:1287 0 0.056
disease of cellular proliferation DOID:14566 0 0.025
artery disease DOID:0050828 0 0.023