Drosophila melanogaster

15 known processes

dpr (Dmel_CG13439)

defective proboscis extension response

(Aliases: CG13439,Dmel\CG13439,Dpr-1,DPR1)

dpr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory perception of taste GO:0050909 25 0.940
detection of sucrose stimulus GO:0009731 1 0.888
single organism behavior GO:0044708 391 0.837
Fly
response to maltose GO:0034286 1 0.810
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.683
detection of chemical stimulus GO:0009593 93 0.664
detection of carbohydrate stimulus GO:0009730 1 0.520
detection of monosaccharide stimulus GO:0034287 1 0.419
detection of light stimulus GO:0009583 58 0.391
sensory perception of chemical stimulus GO:0007606 116 0.381
sensory perception of salty taste GO:0050914 3 0.331
detection of glucose GO:0051594 1 0.286
detection of stimulus involved in sensory perception GO:0050906 92 0.274
sensory perception GO:0007600 196 0.269
detection of hexose stimulus GO:0009732 1 0.210
neurological system process GO:0050877 358 0.210
response to glucose GO:0009749 2 0.187
detection of stimulus GO:0051606 156 0.159
response to monosaccharide GO:0034284 4 0.158
salt aversion GO:0035199 3 0.156
courtship behavior GO:0007619 68 0.132
response to organic substance GO:0010033 284 0.129
Fly
cation transport GO:0006812 110 0.115
Fly
cyclic nucleotide biosynthetic process GO:0009190 25 0.103
response to oxygen containing compound GO:1901700 200 0.093
Fly
response to hexose GO:0009746 3 0.089
response to trehalose GO:0010353 3 0.078
cgmp biosynthetic process GO:0006182 8 0.074
phototransduction visible light GO:0007603 27 0.073
open tracheal system development GO:0007424 204 0.072
aromatic compound catabolic process GO:0019439 166 0.064
response to abiotic stimulus GO:0009628 341 0.061
glycosyl compound catabolic process GO:1901658 112 0.061
response to reactive oxygen species GO:0000302 24 0.061
inter male aggressive behavior GO:0002121 60 0.060
feeding behavior GO:0007631 50 0.059
response to radiation GO:0009314 155 0.059
sensory perception of sweet taste GO:0050916 14 0.056
detection of chemical stimulus involved in sensory perception of taste GO:0050912 13 0.052
ribonucleoside catabolic process GO:0042454 112 0.052
rhodopsin mediated signaling pathway GO:0016056 21 0.051
catabolic process GO:0009056 409 0.051
divalent metal ion transport GO:0070838 26 0.051
Fly
multi organism behavior GO:0051705 175 0.051
cgmp metabolic process GO:0046068 11 0.051
nucleotide catabolic process GO:0009166 109 0.051
organonitrogen compound metabolic process GO:1901564 318 0.049
cellular catabolic process GO:0044248 372 0.048
cellular response to light stimulus GO:0071482 37 0.048
g protein coupled receptor signaling pathway GO:0007186 136 0.046
ion transmembrane transport GO:0034220 122 0.045
carbohydrate derivative biosynthetic process GO:1901137 85 0.044
cyclic nucleotide metabolic process GO:0009187 28 0.043
transmembrane transport GO:0055085 139 0.041
organophosphate metabolic process GO:0019637 195 0.040
chemosensory behavior GO:0007635 106 0.040
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.040
ribonucleoside metabolic process GO:0009119 127 0.039
small molecule metabolic process GO:0044281 305 0.038
ribose phosphate metabolic process GO:0019693 145 0.038
detection of disaccharide stimulus GO:0034288 1 0.038
gtp catabolic process GO:0006184 72 0.038
purine nucleoside catabolic process GO:0006152 112 0.038
glycosyl compound metabolic process GO:1901657 127 0.038
nucleoside triphosphate metabolic process GO:0009141 120 0.038
nucleobase containing compound catabolic process GO:0034655 165 0.038
protein heterooligomerization GO:0051291 4 0.038
guanosine containing compound metabolic process GO:1901068 74 0.037
gtp metabolic process GO:0046039 72 0.037
nucleoside phosphate catabolic process GO:1901292 110 0.037
respiratory system development GO:0060541 213 0.036
response to nutrient levels GO:0031667 114 0.036
purine nucleoside triphosphate catabolic process GO:0009146 108 0.036
purine ribonucleoside catabolic process GO:0046130 112 0.036
purine containing compound catabolic process GO:0072523 112 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.036
organic substance catabolic process GO:1901575 308 0.036
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.036
detection of visible light GO:0009584 38 0.035
regulation of reproductive process GO:2000241 54 0.035
nucleotide metabolic process GO:0009117 161 0.035
purine nucleoside metabolic process GO:0042278 127 0.034
single organism catabolic process GO:0044712 228 0.034
nucleoside phosphate biosynthetic process GO:1901293 34 0.034
nucleoside metabolic process GO:0009116 127 0.034
nucleoside triphosphate catabolic process GO:0009143 108 0.033
response to oxidative stress GO:0006979 86 0.033
detection of abiotic stimulus GO:0009582 66 0.033
purine containing compound metabolic process GO:0072521 155 0.033
ribonucleotide metabolic process GO:0009259 145 0.033
nucleobase containing small molecule metabolic process GO:0055086 174 0.033
male mating behavior GO:0060179 70 0.033
purine nucleotide biosynthetic process GO:0006164 29 0.032
intracellular signal transduction GO:0035556 300 0.032
purine nucleoside triphosphate metabolic process GO:0009144 119 0.032
taxis GO:0042330 304 0.032
metal ion transport GO:0030001 74 0.032
Fly
purine ribonucleotide metabolic process GO:0009150 145 0.032
heterocycle catabolic process GO:0046700 166 0.032
carbohydrate derivative metabolic process GO:1901135 217 0.032
single organism biosynthetic process GO:0044711 206 0.032
ribonucleoside triphosphate catabolic process GO:0009203 108 0.032
cellular nitrogen compound catabolic process GO:0044270 165 0.032
organonitrogen compound biosynthetic process GO:1901566 117 0.031
biological adhesion GO:0022610 138 0.031
guanosine containing compound catabolic process GO:1901069 74 0.031
synaptic transmission GO:0007268 288 0.030
imaginal disc derived appendage development GO:0048737 399 0.030
purine ribonucleotide catabolic process GO:0009154 109 0.030
nucleoside phosphate metabolic process GO:0006753 162 0.030
homeostatic process GO:0042592 199 0.030
tissue morphogenesis GO:0048729 297 0.029
purine nucleotide metabolic process GO:0006163 146 0.029
drinking behavior GO:0042756 2 0.029
organophosphate catabolic process GO:0046434 112 0.029
protein complex assembly GO:0006461 200 0.028
phototransduction GO:0007602 52 0.028
detection of external stimulus GO:0009581 66 0.028
adult behavior GO:0030534 137 0.028
Fly
dendrite development GO:0016358 204 0.028
epiboly involved in wound healing GO:0090505 2 0.028
organonitrogen compound catabolic process GO:1901565 128 0.028
anatomical structure homeostasis GO:0060249 97 0.027
macromolecular complex assembly GO:0065003 256 0.027
regulation of multicellular organismal development GO:2000026 414 0.027
carbohydrate derivative catabolic process GO:1901136 118 0.027
detection of chemical stimulus involved in sensory perception of sweet taste GO:0001582 11 0.027
developmental maturation GO:0021700 172 0.026
larval behavior GO:0030537 42 0.026
cell junction organization GO:0034330 57 0.026
regulation of cell cycle GO:0051726 291 0.025
protein complex biogenesis GO:0070271 201 0.025
ribonucleotide catabolic process GO:0009261 109 0.025
ribonucleoside triphosphate metabolic process GO:0009199 119 0.025
response to light stimulus GO:0009416 124 0.025
cell proliferation GO:0008283 299 0.025
phagocytosis GO:0006909 215 0.024
energy taxis GO:0009453 21 0.024
morphogenesis of an epithelium GO:0002009 276 0.024
purine ribonucleoside metabolic process GO:0046128 127 0.024
appendage development GO:0048736 401 0.023
regulation of behavior GO:0050795 75 0.023
cell division GO:0051301 248 0.023
phototaxis GO:0042331 21 0.023
immune system process GO:0002376 347 0.023
purine ribonucleotide biosynthetic process GO:0009152 28 0.023
response to extracellular stimulus GO:0009991 116 0.023
negative regulation of response to stimulus GO:0048585 258 0.023
ribose phosphate biosynthetic process GO:0046390 28 0.022
sensory organ morphogenesis GO:0090596 260 0.022
locomotory behavior GO:0007626 176 0.022
purine containing compound biosynthetic process GO:0072522 30 0.022
behavioral response to ethanol GO:0048149 49 0.022
Fly
response to temperature stimulus GO:0009266 106 0.022
organic cyclic compound catabolic process GO:1901361 168 0.021
regulation of synapse structure and activity GO:0050803 128 0.021
multi organism reproductive behavior GO:0044705 121 0.020
ion transport GO:0006811 145 0.020
Fly
dendrite morphogenesis GO:0048813 199 0.020
transcription from rna polymerase ii promoter GO:0006366 368 0.020
regulation of multi organism process GO:0043900 131 0.019
nucleoside catabolic process GO:0009164 112 0.019
salivary gland morphogenesis GO:0007435 145 0.019
morphogenesis of embryonic epithelium GO:0016331 94 0.019
defense response to bacterium GO:0042742 178 0.019
divalent inorganic cation transport GO:0072511 30 0.019
Fly
regulation of intracellular signal transduction GO:1902531 236 0.019
larval locomotory behavior GO:0008345 27 0.018
detection of chemical stimulus involved in sensory perception of smell GO:0050911 50 0.018
establishment of localization in cell GO:0051649 402 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
programmed cell death GO:0012501 257 0.018
vesicle mediated transport GO:0016192 381 0.018
cell cell junction organization GO:0045216 55 0.018
purine nucleotide catabolic process GO:0006195 109 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.018
cell adhesion involved in heart morphogenesis GO:0061343 12 0.017
regulation of tube architecture open tracheal system GO:0035152 68 0.017
nuclear division GO:0000280 332 0.017
regulation of catalytic activity GO:0050790 185 0.017
cell cell adhesion GO:0098609 26 0.017
protein localization GO:0008104 284 0.017
protein transport GO:0015031 155 0.017
innate immune response GO:0045087 144 0.017
wing disc morphogenesis GO:0007472 344 0.016
cellular response to radiation GO:0071478 52 0.016
body morphogenesis GO:0010171 2 0.016
sensory perception of pain GO:0019233 4 0.016
gland morphogenesis GO:0022612 145 0.016
actin filament based process GO:0030029 220 0.016
cellular response to water stimulus GO:0071462 2 0.016
positive regulation of cell communication GO:0010647 250 0.016
regulation of cellular component biogenesis GO:0044087 201 0.016
single organism cellular localization GO:1902580 180 0.016
imaginal disc derived wing morphogenesis GO:0007476 337 0.015
endocytosis GO:0006897 310 0.015
regulation of localization GO:0032879 275 0.015
cyclic purine nucleotide metabolic process GO:0052652 25 0.015
aggressive behavior GO:0002118 63 0.015
telencephalon development GO:0021537 2 0.015
negative regulation of gene expression GO:0010629 387 0.015
immune response GO:0006955 246 0.015
multicellular organismal homeostasis GO:0048871 41 0.015
growth GO:0040007 359 0.015
mating behavior GO:0007617 106 0.015
small gtpase mediated signal transduction GO:0007264 88 0.015
response to hyperoxia GO:0055093 3 0.015
store operated calcium entry GO:0002115 3 0.015
Fly
proteolysis GO:0006508 192 0.015
regulation of cell development GO:0060284 215 0.014
negative regulation of biosynthetic process GO:0009890 277 0.014
male courtship behavior GO:0008049 63 0.014
response to decreased oxygen levels GO:0036293 58 0.014
wound healing spreading of epidermal cells GO:0035313 1 0.014
compound eye morphogenesis GO:0001745 249 0.014
cell junction assembly GO:0034329 42 0.014
synapse assembly GO:0007416 143 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
negative regulation of growth GO:0045926 84 0.014
regulation of transport GO:0051049 181 0.014
multicellular organismal reproductive behavior GO:0033057 110 0.014
compound eye development GO:0048749 307 0.014
forebrain development GO:0030900 2 0.014
response to biotic stimulus GO:0009607 294 0.014
positive regulation of signal transduction GO:0009967 223 0.014
regulation of anatomical structure size GO:0090066 163 0.014
inorganic ion transmembrane transport GO:0098660 73 0.013
regulation of cell cycle process GO:0010564 181 0.013
cell adhesion GO:0007155 136 0.013
positive regulation of biosynthetic process GO:0009891 316 0.013
death GO:0016265 284 0.013
post embryonic appendage morphogenesis GO:0035120 385 0.013
rna processing GO:0006396 147 0.013
positive regulation of signaling GO:0023056 243 0.013
carboxylic acid metabolic process GO:0019752 92 0.013
establishment of organelle localization GO:0051656 122 0.013
regulation of synapse organization GO:0050807 110 0.013
negative regulation of signaling GO:0023057 219 0.013
septate junction assembly GO:0019991 26 0.013
organelle assembly GO:0070925 198 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
behavioral response to pain GO:0048266 3 0.013
cellular response to chemical stimulus GO:0070887 199 0.013
cellular response to hexose stimulus GO:0071331 1 0.013
cell migration GO:0016477 238 0.013
organic substance transport GO:0071702 257 0.013
sodium ion transport GO:0006814 22 0.013
immune response activating signal transduction GO:0002757 2 0.013
phosphorylation GO:0016310 294 0.013
notch signaling pathway GO:0007219 120 0.013
response to oxygen levels GO:0070482 59 0.013
eye morphogenesis GO:0048592 260 0.012
ras protein signal transduction GO:0007265 88 0.012
response to disaccharide GO:0034285 12 0.012
cellular response to carbohydrate stimulus GO:0071322 4 0.012
regulation of immune system process GO:0002682 176 0.012
mechanosensory behavior GO:0007638 12 0.012
immune response regulating signaling pathway GO:0002764 2 0.012
negative regulation of developmental process GO:0051093 201 0.012
positive regulation of response to stimulus GO:0048584 323 0.012
cell motility GO:0048870 251 0.012
epiboly GO:0090504 2 0.012
response to other organism GO:0051707 293 0.012
regionalization GO:0003002 416 0.012
regulation of camp biosynthetic process GO:0030817 12 0.012
positive regulation of molecular function GO:0044093 136 0.012
synaptic growth at neuromuscular junction GO:0051124 119 0.011
mating GO:0007618 120 0.011
camera type eye development GO:0043010 4 0.011
cellular protein modification process GO:0006464 438 0.011
mitotic nuclear division GO:0007067 213 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.011
positive regulation of catabolic process GO:0009896 105 0.011
organophosphate biosynthetic process GO:0090407 46 0.011
regulation of tube size open tracheal system GO:0035151 43 0.011
regulation of cell differentiation GO:0045595 302 0.011
organic acid metabolic process GO:0006082 103 0.011
regulation of neurogenesis GO:0050767 158 0.011
regulation of vesicle mediated transport GO:0060627 59 0.011
cell death GO:0008219 279 0.011
localization of cell GO:0051674 257 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
salivary gland development GO:0007431 162 0.011
cellular macromolecule localization GO:0070727 220 0.011
single organism intracellular transport GO:1902582 207 0.011
developmental growth GO:0048589 280 0.011
cellular amino acid metabolic process GO:0006520 61 0.011
response to organonitrogen compound GO:0010243 75 0.011
pattern recognition receptor signaling pathway GO:0002221 2 0.011
synapse organization GO:0050808 196 0.011
cellular response to organic substance GO:0071310 132 0.011
mrna processing GO:0006397 104 0.011
gliogenesis GO:0042063 80 0.011
regulation of catabolic process GO:0009894 170 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
salivary gland histolysis GO:0035070 88 0.011
regulation of synaptic transmission GO:0050804 69 0.011
regulation of organelle organization GO:0033043 196 0.011
actin cytoskeleton organization GO:0030036 206 0.011
positive regulation of cellular biosynthetic process GO:0031328 316 0.011
muscle structure development GO:0061061 224 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
positive regulation of rna biosynthetic process GO:1902680 266 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.011
regulation of mitotic cell cycle phase transition GO:1901990 130 0.011
regulation of synapse assembly GO:0051963 94 0.011
regulation of nervous system development GO:0051960 248 0.011
protein phosphorylation GO:0006468 169 0.010
positive regulation of transcription dna templated GO:0045893 266 0.010
multi multicellular organism process GO:0044706 123 0.010
water homeostasis GO:0030104 3 0.010
wound healing spreading of cells GO:0044319 2 0.010
positive regulation of cellular catabolic process GO:0031331 95 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.010
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.010
oxoacid metabolic process GO:0043436 103 0.010
response to carbohydrate GO:0009743 15 0.010
cell cycle phase transition GO:0044770 140 0.010
regulation of cell maturation GO:1903429 27 0.010

dpr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
respiratory system disease DOID:1579 0 0.127
lower respiratory tract disease DOID:0050161 0 0.127
disease of anatomical entity DOID:7 0 0.127
renal tubular transport disease DOID:447 0 0.111
kidney disease DOID:557 0 0.111
urinary system disease DOID:18 0 0.111
bronchial disease DOID:1176 0 0.033
bronchiectasis DOID:9563 0 0.033
nervous system disease DOID:863 0 0.016
disease of metabolism DOID:0014667 0 0.012
liddle syndrome DOID:0050477 0 0.011
disease of cellular proliferation DOID:14566 0 0.010