Drosophila melanogaster

31 known processes

CG10440 (Dmel_CG10440)

CG10440 gene product from transcript CG10440-RA

(Aliases: Dmel\CG10440)

CG10440 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.135
Human
imaginal disc derived appendage morphogenesis GO:0035114 395 0.113
negative regulation of cellular biosynthetic process GO:0031327 277 0.110
Human
negative regulation of cellular metabolic process GO:0031324 382 0.110
Human
positive regulation of nucleic acid templated transcription GO:1903508 266 0.100
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.090
Human
eye morphogenesis GO:0048592 260 0.076
neuron projection guidance GO:0097485 241 0.076
negative regulation of transcription dna templated GO:0045892 237 0.075
Human
appendage morphogenesis GO:0035107 397 0.075
positive regulation of macromolecule metabolic process GO:0010604 405 0.072
transcription from rna polymerase ii promoter GO:0006366 368 0.069
negative regulation of rna metabolic process GO:0051253 251 0.067
Human
imaginal disc derived appendage development GO:0048737 399 0.066
wing disc morphogenesis GO:0007472 344 0.065
post embryonic appendage morphogenesis GO:0035120 385 0.064
protein modification process GO:0036211 438 0.062
cellular protein modification process GO:0006464 438 0.061
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.060
positive regulation of rna biosynthetic process GO:1902680 266 0.059
appendage development GO:0048736 401 0.057
imaginal disc derived wing morphogenesis GO:0007476 337 0.056
negative regulation of nucleic acid templated transcription GO:1903507 240 0.055
Human
regionalization GO:0003002 416 0.055
positive regulation of gene expression GO:0010628 290 0.052
tissue morphogenesis GO:0048729 297 0.052
compound eye development GO:0048749 307 0.050
ovarian follicle cell development GO:0030707 248 0.049
positive regulation of rna metabolic process GO:0051254 271 0.049
multi multicellular organism process GO:0044706 123 0.049
chemotaxis GO:0006935 249 0.049
axon development GO:0061564 297 0.049
negative regulation of biosynthetic process GO:0009890 277 0.049
Human
regulation of multicellular organismal development GO:2000026 414 0.048
vesicle mediated transport GO:0016192 381 0.047
taxis GO:0042330 304 0.047
epithelial cell development GO:0002064 274 0.047
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.046
negative regulation of rna biosynthetic process GO:1902679 240 0.044
Human
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.043
positive regulation of transcription dna templated GO:0045893 266 0.042
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.041
Human
establishment or maintenance of cell polarity GO:0007163 167 0.040
axon guidance GO:0007411 233 0.040
cell motility GO:0048870 251 0.040
cell division GO:0051301 248 0.040
endocytosis GO:0006897 310 0.039
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.039
axonogenesis GO:0007409 290 0.038
positive regulation of biosynthetic process GO:0009891 316 0.038
regulation of cell differentiation GO:0045595 302 0.037
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.037
Human
spindle organization GO:0007051 253 0.036
positive regulation of signaling GO:0023056 243 0.036
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.036
regulation of cell cycle GO:0051726 291 0.036
negative regulation of gene expression GO:0010629 387 0.035
Human
defense response GO:0006952 300 0.035
cell maturation GO:0048469 144 0.035
eye development GO:0001654 323 0.035
dendrite development GO:0016358 204 0.034
catabolic process GO:0009056 409 0.034
epithelial cell differentiation GO:0030855 322 0.034
cellular catabolic process GO:0044248 372 0.033
phosphorylation GO:0016310 294 0.033
sensory organ morphogenesis GO:0090596 260 0.033
aggressive behavior GO:0002118 63 0.033
positive regulation of cellular biosynthetic process GO:0031328 316 0.032
developmental growth GO:0048589 280 0.032
death GO:0016265 284 0.032
notch signaling pathway GO:0007219 120 0.032
compound eye photoreceptor cell differentiation GO:0001751 140 0.032
cell migration GO:0016477 238 0.032
positive regulation of cell communication GO:0010647 250 0.031
positive regulation of response to stimulus GO:0048584 323 0.031
segmentation GO:0035282 207 0.031
male mating behavior GO:0060179 70 0.031
oxoacid metabolic process GO:0043436 103 0.031
homeostatic process GO:0042592 199 0.031
organic acid metabolic process GO:0006082 103 0.030
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.030
reproductive behavior GO:0019098 122 0.030
organelle fission GO:0048285 340 0.030
neurological system process GO:0050877 358 0.029
axis specification GO:0009798 167 0.029
carboxylic acid metabolic process GO:0019752 92 0.029
regulation of localization GO:0032879 275 0.029
embryonic pattern specification GO:0009880 174 0.029
camera type eye development GO:0043010 4 0.029
body morphogenesis GO:0010171 2 0.028
organonitrogen compound metabolic process GO:1901564 318 0.028
regulation of intracellular signal transduction GO:1902531 236 0.027
organic substance catabolic process GO:1901575 308 0.027
compound eye morphogenesis GO:0001745 249 0.027
male courtship behavior GO:0008049 63 0.027
dendrite morphogenesis GO:0048813 199 0.027
forebrain development GO:0030900 2 0.026
g protein coupled receptor signaling pathway GO:0007186 136 0.026
regulation of molecular function GO:0065009 217 0.026
phagocytosis GO:0006909 215 0.026
brain development GO:0007420 120 0.026
small molecule metabolic process GO:0044281 305 0.026
intracellular signal transduction GO:0035556 300 0.026
central nervous system development GO:0007417 201 0.026
eye photoreceptor cell differentiation GO:0001754 145 0.025
response to oxygen containing compound GO:1901700 200 0.025
male gamete generation GO:0048232 201 0.025
epithelial cell migration GO:0010631 148 0.025
protein localization GO:0008104 284 0.025
macromolecular complex assembly GO:0065003 256 0.025
chromosome organization GO:0051276 360 0.025
embryo development ending in birth or egg hatching GO:0009792 152 0.025
Zebrafish
locomotory behavior GO:0007626 176 0.025
larval development GO:0002164 104 0.024
cellular amino acid metabolic process GO:0006520 61 0.024
cell adhesion GO:0007155 136 0.024
courtship behavior GO:0007619 68 0.024
programmed cell death GO:0012501 257 0.024
salivary gland development GO:0007431 162 0.023
anatomical structure homeostasis GO:0060249 97 0.023
exocrine system development GO:0035272 162 0.023
signal transduction by phosphorylation GO:0023014 107 0.023
multi organism behavior GO:0051705 175 0.023
morphogenesis of an epithelium GO:0002009 276 0.023
stem cell proliferation GO:0072089 88 0.023
connective tissue development GO:0061448 3 0.023
ameboidal type cell migration GO:0001667 151 0.023
regulation of cellular catabolic process GO:0031329 157 0.023
multicellular organismal reproductive behavior GO:0033057 110 0.023
columnar cuboidal epithelial cell development GO:0002066 249 0.023
inter male aggressive behavior GO:0002121 60 0.023
regulation of nervous system development GO:0051960 248 0.022
response to other organism GO:0051707 293 0.022
anterior posterior pattern specification GO:0009952 136 0.022
nuclear division GO:0000280 332 0.022
regulation of cellular protein metabolic process GO:0032268 243 0.022
blastoderm segmentation GO:0007350 159 0.022
neural precursor cell proliferation GO:0061351 75 0.022
response to organic substance GO:0010033 284 0.022
establishment of localization in cell GO:0051649 402 0.022
cell death GO:0008219 279 0.022
positive regulation of multicellular organismal process GO:0051240 143 0.021
regulation of catalytic activity GO:0050790 185 0.021
imaginal disc derived leg morphogenesis GO:0007480 80 0.021
leg disc development GO:0035218 92 0.021
regulation of transport GO:0051049 181 0.021
proteolysis GO:0006508 192 0.021
response to biotic stimulus GO:0009607 294 0.021
embryonic development via the syncytial blastoderm GO:0001700 148 0.021
tissue migration GO:0090130 155 0.020
negative regulation of cell differentiation GO:0045596 143 0.020
immune system process GO:0002376 347 0.020
cellular ketone metabolic process GO:0042180 24 0.020
cellular response to chemical stimulus GO:0070887 199 0.020
dorsal ventral pattern formation GO:0009953 133 0.020
chaeta development GO:0022416 97 0.020
positive regulation of signal transduction GO:0009967 223 0.020
response to abiotic stimulus GO:0009628 341 0.020
mapk cascade GO:0000165 107 0.020
regulation of cell cycle process GO:0010564 181 0.020
synapse organization GO:0050808 196 0.020
regulation of phosphate metabolic process GO:0019220 210 0.019
positive regulation of transport GO:0051050 92 0.019
regulation of catabolic process GO:0009894 170 0.019
leg disc morphogenesis GO:0007478 80 0.019
protein phosphorylation GO:0006468 169 0.019
mitotic nuclear division GO:0007067 213 0.019
tube development GO:0035295 244 0.019
cell proliferation GO:0008283 299 0.019
regulation of mitotic cell cycle GO:0007346 190 0.019
mitotic spindle organization GO:0007052 220 0.019
single organism biosynthetic process GO:0044711 206 0.019
positive regulation of cellular component organization GO:0051130 156 0.019
single organism behavior GO:0044708 391 0.019
amine metabolic process GO:0009308 12 0.019
regulation of programmed cell death GO:0043067 152 0.019
regulation of anatomical structure morphogenesis GO:0022603 242 0.019
spermatid development GO:0007286 98 0.018
regulation of protein metabolic process GO:0051246 256 0.018
response to bacterium GO:0009617 198 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
respiratory system development GO:0060541 213 0.018
telencephalon development GO:0021537 2 0.018
positive regulation of cell migration GO:0030335 2 0.018
single organism catabolic process GO:0044712 228 0.018
negative regulation of response to stimulus GO:0048585 258 0.018
Zebrafish Fly
response to external biotic stimulus GO:0043207 293 0.018
response to lipopolysaccharide GO:0032496 4 0.018
gland development GO:0048732 191 0.018
developmental maturation GO:0021700 172 0.018
regulation of growth GO:0040008 233 0.018
pigment metabolic process GO:0042440 84 0.017
embryonic axis specification GO:0000578 107 0.017
protein transport GO:0015031 155 0.017
eye photoreceptor cell development GO:0042462 81 0.017
protein modification by small protein conjugation or removal GO:0070647 106 0.017
carbohydrate derivative metabolic process GO:1901135 217 0.017
secretion GO:0046903 109 0.017
photoreceptor cell development GO:0042461 96 0.017
cellular amine metabolic process GO:0044106 12 0.017
spermatogenesis GO:0007283 200 0.017
muscle structure development GO:0061061 224 0.017
steroid catabolic process GO:0006706 1 0.017
positive regulation of cell motility GO:2000147 3 0.017
establishment of organelle localization GO:0051656 122 0.017
open tracheal system development GO:0007424 204 0.017
gland morphogenesis GO:0022612 145 0.017
regulation of notch signaling pathway GO:0008593 100 0.017
salivary gland morphogenesis GO:0007435 145 0.017
detection of external stimulus GO:0009581 66 0.017
response to radiation GO:0009314 155 0.017
cellular response to dna damage stimulus GO:0006974 223 0.017
regulation of mapk cascade GO:0043408 92 0.017
cellularization GO:0007349 90 0.017
enzyme linked receptor protein signaling pathway GO:0007167 179 0.017
organic cyclic compound catabolic process GO:1901361 168 0.017
mating behavior GO:0007617 106 0.016
compound eye photoreceptor development GO:0042051 78 0.016
negative regulation of signal transduction GO:0009968 206 0.016
Zebrafish
growth GO:0040007 359 0.016
meiotic cell cycle GO:0051321 171 0.016
muscle organ development GO:0007517 127 0.016
localization of cell GO:0051674 257 0.016
organelle assembly GO:0070925 198 0.016
detection of stimulus GO:0051606 156 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
regulation of hydrolase activity GO:0051336 97 0.016
organic substance transport GO:0071702 257 0.016
biological adhesion GO:0022610 138 0.016
multi organism reproductive behavior GO:0044705 121 0.016
chromatin organization GO:0006325 207 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
single organism intracellular transport GO:1902582 207 0.016
mating GO:0007618 120 0.016
photoreceptor cell differentiation GO:0046530 170 0.015
hindbrain development GO:0030902 2 0.015
sex differentiation GO:0007548 81 0.015
neuron recognition GO:0008038 101 0.015
anterior posterior axis specification GO:0009948 109 0.015
digestive tract morphogenesis GO:0048546 127 0.015
tube morphogenesis GO:0035239 191 0.015
neuroblast proliferation GO:0007405 74 0.015
apoptotic process GO:0006915 159 0.015
cytoplasmic transport GO:0016482 130 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
immune response GO:0006955 246 0.015
negative regulation of cell communication GO:0010648 223 0.015
Zebrafish
regulation of peptidase activity GO:0052547 39 0.015
digestive tract development GO:0048565 149 0.015
ras protein signal transduction GO:0007265 88 0.015
regulation of apoptotic process GO:0042981 130 0.014
regulation of organ morphogenesis GO:2000027 78 0.014
regulation of phosphorylation GO:0042325 147 0.014
innate immune response GO:0045087 144 0.014
establishment of planar polarity GO:0001736 87 0.014
morphogenesis of a polarized epithelium GO:0001738 93 0.014
regulation of response to stress GO:0080134 200 0.014
autophagy GO:0006914 108 0.014
mesenchymal cell development GO:0014031 1 0.014
rna localization GO:0006403 115 0.014
positive regulation of molecular function GO:0044093 136 0.014
negative regulation of molecular function GO:0044092 51 0.014
cellular protein localization GO:0034613 160 0.014
sensory perception GO:0007600 196 0.014
hormone catabolic process GO:0042447 3 0.014
cellular homeostasis GO:0019725 80 0.014
peptidyl amino acid modification GO:0018193 105 0.014
response to nutrient levels GO:0031667 114 0.014
circadian behavior GO:0048512 76 0.014
response to organic cyclic compound GO:0014070 89 0.014
glycoprotein biosynthetic process GO:0009101 41 0.014
anterior posterior axis specification embryo GO:0008595 103 0.014
actin cytoskeleton organization GO:0030036 206 0.013
single organism cellular localization GO:1902580 180 0.013
kidney development GO:0001822 3 0.013
protein maturation GO:0051604 71 0.013
regulation of neurogenesis GO:0050767 158 0.013
protein modification by small protein conjugation GO:0032446 79 0.013
imaginal disc pattern formation GO:0007447 91 0.013
protein ubiquitination GO:0016567 70 0.013
regulation of anatomical structure size GO:0090066 163 0.013
regulation of cell cycle phase transition GO:1901987 130 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
regulation of proteolysis GO:0030162 87 0.013
wnt signaling pathway GO:0016055 98 0.013
Zebrafish
developmental programmed cell death GO:0010623 138 0.013
organophosphate metabolic process GO:0019637 195 0.013
meiotic nuclear division GO:0007126 151 0.013
regulation of behavior GO:0050795 75 0.013
Fly
cellular macromolecule catabolic process GO:0044265 136 0.013
protein processing GO:0016485 68 0.013
regulation of cell death GO:0010941 173 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
cell cell adhesion GO:0098609 26 0.013
epithelium migration GO:0090132 148 0.013
endomembrane system organization GO:0010256 119 0.013
positive regulation of hydrolase activity GO:0051345 78 0.013
embryonic morphogenesis GO:0048598 206 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
response to alcohol GO:0097305 95 0.013
regulation of wnt signaling pathway GO:0030111 68 0.013
Zebrafish
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
organonitrogen compound biosynthetic process GO:1901566 117 0.012
head development GO:0060322 135 0.012
rna processing GO:0006396 147 0.012
retina development in camera type eye GO:0060041 4 0.012
mitotic cell cycle phase transition GO:0044772 138 0.012
tripartite regional subdivision GO:0007351 103 0.012
cell cycle checkpoint GO:0000075 95 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.012
spinal cord development GO:0021510 1 0.012
lateral inhibition GO:0046331 206 0.012
adult behavior GO:0030534 137 0.012
positive regulation of protein metabolic process GO:0051247 128 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
regulation of cell development GO:0060284 215 0.012
response to light stimulus GO:0009416 124 0.012
regulation of mitotic cell cycle phase transition GO:1901990 130 0.012
positive regulation of peptidase activity GO:0010952 29 0.012
cell cycle phase transition GO:0044770 140 0.012
neuromuscular junction development GO:0007528 149 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
regulation of endopeptidase activity GO:0052548 36 0.012
macromolecule catabolic process GO:0009057 161 0.012
reproductive system development GO:0061458 74 0.012
negative regulation of nervous system development GO:0051961 92 0.012
positive regulation of cell death GO:0010942 69 0.012
heterocycle catabolic process GO:0046700 166 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
response to monosaccharide GO:0034284 4 0.012
regulation of protein modification process GO:0031399 112 0.012
regulation of defense response GO:0031347 102 0.012
intracellular transport GO:0046907 228 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
cellular macromolecule localization GO:0070727 220 0.012
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
cell fate specification GO:0001708 71 0.012
carbohydrate metabolic process GO:0005975 82 0.012
camera type eye morphogenesis GO:0048593 2 0.012
single organism carbohydrate metabolic process GO:0044723 72 0.012
regulation of organelle organization GO:0033043 196 0.011
tissue death GO:0016271 102 0.011
establishment of tissue polarity GO:0007164 87 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
histolysis GO:0007559 102 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
response to hexose GO:0009746 3 0.011
developmental growth involved in morphogenesis GO:0060560 65 0.011
negative regulation of signaling GO:0023057 219 0.011
Zebrafish
regulation of cell projection organization GO:0031344 92 0.011
cardiovascular system development GO:0072358 82 0.011
positive regulation of mapk cascade GO:0043410 63 0.011
instar larval development GO:0002168 55 0.011
cellular response to ethanol GO:0071361 4 0.011
androgen metabolic process GO:0008209 1 0.011
rna splicing via transesterification reactions GO:0000375 73 0.011
organic hydroxy compound metabolic process GO:1901615 83 0.011
nitrogen compound transport GO:0071705 85 0.011
epithelial cell migration open tracheal system GO:0007427 32 0.011
positive regulation of apoptotic process GO:0043065 47 0.011
cell cell signaling involved in cell fate commitment GO:0045168 210 0.011
sulfur compound metabolic process GO:0006790 59 0.011
purine nucleotide catabolic process GO:0006195 109 0.011
regulation of small gtpase mediated signal transduction GO:0051056 93 0.011
negative regulation of developmental process GO:0051093 201 0.011
purine containing compound metabolic process GO:0072521 155 0.011
neuron fate commitment GO:0048663 50 0.011
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.011
circulatory system development GO:0072359 82 0.011
positive regulation of catabolic process GO:0009896 105 0.011
regulation of mrna processing GO:0050684 71 0.011
glycosyl compound catabolic process GO:1901658 112 0.011
cellular response to organic substance GO:0071310 132 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
meiotic cell cycle process GO:1903046 132 0.011
covalent chromatin modification GO:0016569 106 0.011
defense response to other organism GO:0098542 225 0.011
skeletal muscle fiber development GO:0048741 3 0.011
protein complex biogenesis GO:0070271 201 0.011
hindgut morphogenesis GO:0007442 58 0.010
response to heat GO:0009408 63 0.010
oocyte axis specification GO:0007309 108 0.010
gastrulation GO:0007369 70 0.010
spermatid differentiation GO:0048515 114 0.010
regulation of response to external stimulus GO:0032101 115 0.010
positive regulation of phosphorylation GO:0042327 87 0.010
wing disc pattern formation GO:0035222 66 0.010
intracellular mrna localization GO:0008298 66 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
rhythmic process GO:0048511 106 0.010
imaginal disc derived leg segmentation GO:0036011 26 0.010
carbohydrate derivative biosynthetic process GO:1901137 85 0.010
organonitrogen compound catabolic process GO:1901565 128 0.010
eggshell formation GO:0030703 105 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.010
positive regulation of nervous system development GO:0051962 69 0.010
positive regulation of cell differentiation GO:0045597 64 0.010
aromatic compound catabolic process GO:0019439 166 0.010
rna splicing GO:0008380 83 0.010
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.010
salivary gland histolysis GO:0035070 88 0.010
purine ribonucleotide metabolic process GO:0009150 145 0.010
response to extracellular stimulus GO:0009991 116 0.010
positive regulation of developmental process GO:0051094 143 0.010
reproductive structure development GO:0048608 74 0.010
spindle assembly GO:0051225 80 0.010

CG10440 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.085
nervous system disease DOID:863 0 0.021
musculoskeletal system disease DOID:17 0 0.017
disease of metabolism DOID:0014667 0 0.015
inherited metabolic disorder DOID:655 0 0.015
disease of cellular proliferation DOID:14566 0 0.012
sensory system disease DOID:0050155 0 0.011
cancer DOID:162 0 0.010