Drosophila melanogaster

0 known processes

Las (Dmel_CG5231)

Lipoic acid synthase

(Aliases: Dmel\CG5231,CG5231)

Las biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small molecule metabolic process GO:0044281 305 0.070
mitochondrion organization GO:0007005 65 0.067
organonitrogen compound metabolic process GO:1901564 318 0.065
neurological system process GO:0050877 358 0.051
single organism biosynthetic process GO:0044711 206 0.041
organonitrogen compound biosynthetic process GO:1901566 117 0.040
establishment of localization in cell GO:0051649 402 0.038
organic acid metabolic process GO:0006082 103 0.035
single organism membrane organization GO:0044802 93 0.034
vesicle mediated transport GO:0016192 381 0.033
purine containing compound metabolic process GO:0072521 155 0.033
death GO:0016265 284 0.031
developmental growth GO:0048589 280 0.031
single organism cellular localization GO:1902580 180 0.030
oxoacid metabolic process GO:0043436 103 0.029
cellular catabolic process GO:0044248 372 0.029
carboxylic acid metabolic process GO:0019752 92 0.028
carbohydrate derivative metabolic process GO:1901135 217 0.028
nucleobase containing small molecule metabolic process GO:0055086 174 0.028
organophosphate metabolic process GO:0019637 195 0.027
single organism intracellular transport GO:1902582 207 0.027
response to abiotic stimulus GO:0009628 341 0.027
single organism behavior GO:0044708 391 0.027
immune response activating signal transduction GO:0002757 2 0.026
ribonucleoside metabolic process GO:0009119 127 0.026
purine ribonucleoside metabolic process GO:0046128 127 0.026
nucleotide metabolic process GO:0009117 161 0.026
phagocytosis GO:0006909 215 0.026
endocytosis GO:0006897 310 0.025
phosphorylation GO:0016310 294 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.025
regulation of cellular amine metabolic process GO:0033238 3 0.025
negative regulation of cellular metabolic process GO:0031324 382 0.025
nucleoside triphosphate metabolic process GO:0009141 120 0.025
cellular macromolecule localization GO:0070727 220 0.024
phosphatidylethanolamine metabolic process GO:0046337 1 0.024
negative regulation of biosynthetic process GO:0009890 277 0.024
nucleoside phosphate biosynthetic process GO:1901293 34 0.024
nucleoside phosphate metabolic process GO:0006753 162 0.024
ribonucleoside triphosphate metabolic process GO:0009199 119 0.023
organic substance transport GO:0071702 257 0.023
positive regulation of response to stimulus GO:0048584 323 0.022
protein complex biogenesis GO:0070271 201 0.022
organic substance catabolic process GO:1901575 308 0.022
intracellular signal transduction GO:0035556 300 0.022
epithelial cell differentiation GO:0030855 322 0.022
macromolecular complex assembly GO:0065003 256 0.022
protein transport GO:0015031 155 0.021
cellular amino acid metabolic process GO:0006520 61 0.021
nucleoside metabolic process GO:0009116 127 0.021
epithelial cell development GO:0002064 274 0.021
body morphogenesis GO:0010171 2 0.021
cellular amine metabolic process GO:0044106 12 0.021
ribonucleotide metabolic process GO:0009259 145 0.020
response to organic substance GO:0010033 284 0.020
ribose phosphate metabolic process GO:0019693 145 0.020
oocyte differentiation GO:0009994 145 0.020
cytoplasmic transport GO:0016482 130 0.020
catabolic process GO:0009056 409 0.020
detection of stimulus GO:0051606 156 0.020
regulation of intracellular signal transduction GO:1902531 236 0.020
protein complex assembly GO:0006461 200 0.020
response to biotic stimulus GO:0009607 294 0.019
intracellular transport GO:0046907 228 0.019
negative regulation of response to stimulus GO:0048585 258 0.019
negative regulation of cellular biosynthetic process GO:0031327 277 0.019
amine metabolic process GO:0009308 12 0.019
purine nucleotide metabolic process GO:0006163 146 0.019
purine containing compound biosynthetic process GO:0072522 30 0.019
defense response to other organism GO:0098542 225 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.019
regionalization GO:0003002 416 0.019
purine ribonucleotide metabolic process GO:0009150 145 0.018
immune response regulating signaling pathway GO:0002764 2 0.018
positive regulation of signaling GO:0023056 243 0.018
sensory perception GO:0007600 196 0.018
lipid metabolic process GO:0006629 121 0.018
positive regulation of biosynthetic process GO:0009891 316 0.018
purine nucleotide biosynthetic process GO:0006164 29 0.018
regulation of cell cycle GO:0051726 291 0.017
ribose phosphate biosynthetic process GO:0046390 28 0.017
positive regulation of cell communication GO:0010647 250 0.017
response to other organism GO:0051707 293 0.017
purine nucleoside metabolic process GO:0042278 127 0.017
response to bacterium GO:0009617 198 0.017
response to lipopolysaccharide GO:0032496 4 0.017
regulation of phosphate metabolic process GO:0019220 210 0.017
membrane organization GO:0061024 112 0.017
regulation of localization GO:0032879 275 0.016
response to external biotic stimulus GO:0043207 293 0.016
camera type eye development GO:0043010 4 0.016
response to oxygen containing compound GO:1901700 200 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.016
single organism catabolic process GO:0044712 228 0.016
atp metabolic process GO:0046034 49 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.016
locomotory behavior GO:0007626 176 0.016
purine ribonucleotide biosynthetic process GO:0009152 28 0.016
negative regulation of gene expression GO:0010629 387 0.016
organelle assembly GO:0070925 198 0.016
carbohydrate derivative biosynthetic process GO:1901137 85 0.016
rna processing GO:0006396 147 0.016
homeostatic process GO:0042592 199 0.016
establishment of protein localization GO:0045184 163 0.015
cellular response to chemical stimulus GO:0070887 199 0.015
negative regulation of signaling GO:0023057 219 0.015
spermatogenesis GO:0007283 200 0.015
growth GO:0040007 359 0.015
glycosyl compound metabolic process GO:1901657 127 0.015
ethanolamine containing compound metabolic process GO:0042439 4 0.015
purine nucleoside monophosphate metabolic process GO:0009126 50 0.015
response to organophosphorus GO:0046683 2 0.015
cell death GO:0008219 279 0.015
defense response GO:0006952 300 0.015
positive regulation of macromolecule metabolic process GO:0010604 405 0.015
sex differentiation GO:0007548 81 0.015
protein localization GO:0008104 284 0.015
cellular protein modification process GO:0006464 438 0.015
defense response to bacterium GO:0042742 178 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.014
negative regulation of cell communication GO:0010648 223 0.014
segmentation GO:0035282 207 0.014
regulation of transport GO:0051049 181 0.014
immune response GO:0006955 246 0.014
regulation of cellular protein metabolic process GO:0032268 243 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.014
embryonic axis specification GO:0000578 107 0.014
positive regulation of signal transduction GO:0009967 223 0.013
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
organophosphate biosynthetic process GO:0090407 46 0.013
negative regulation of developmental process GO:0051093 201 0.013
regulation of developmental growth GO:0048638 174 0.013
programmed cell death GO:0012501 257 0.013
gland development GO:0048732 191 0.013
regulation of immune system process GO:0002682 176 0.013
detection of stimulus involved in sensory perception GO:0050906 92 0.013
transcription from rna polymerase ii promoter GO:0006366 368 0.012
response to wounding GO:0009611 94 0.012
cell proliferation GO:0008283 299 0.012
regulation of cell death GO:0010941 173 0.012
kidney development GO:0001822 3 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
protein modification process GO:0036211 438 0.012
pattern recognition receptor signaling pathway GO:0002221 2 0.012
regulation of molecular function GO:0065009 217 0.012
multicellular organismal aging GO:0010259 140 0.012
activation of innate immune response GO:0002218 4 0.012
male gamete generation GO:0048232 201 0.012
eye development GO:0001654 323 0.012
protein targeting GO:0006605 64 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.012
transmembrane transport GO:0055085 139 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
open tracheal system development GO:0007424 204 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
positive regulation of cellular biosynthetic process GO:0031328 316 0.012
columnar cuboidal epithelial cell development GO:0002066 249 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.012
ovarian follicle cell development GO:0030707 248 0.012
regulation of response to stress GO:0080134 200 0.012
compound eye morphogenesis GO:0001745 249 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
protein transmembrane transport GO:0071806 4 0.012
endomembrane system organization GO:0010256 119 0.012
embryonic pattern specification GO:0009880 174 0.012
actin filament based process GO:0030029 220 0.011
ribonucleotide biosynthetic process GO:0009260 28 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
regulation of defense response GO:0031347 102 0.011
oligosaccharide transport GO:0015772 2 0.011
response to glucose GO:0009749 2 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
regulation of catalytic activity GO:0050790 185 0.011
ion transport GO:0006811 145 0.011
determination of adult lifespan GO:0008340 137 0.011
cellular response to dna damage stimulus GO:0006974 223 0.011
aromatic compound catabolic process GO:0019439 166 0.011
negative regulation of signal transduction GO:0009968 206 0.011
regulation of growth GO:0040008 233 0.011
axis specification GO:0009798 167 0.011
intracellular protein transport GO:0006886 104 0.011
tripartite regional subdivision GO:0007351 103 0.011
response to nutrient levels GO:0031667 114 0.011
innate immune response GO:0045087 144 0.011
imaginal disc derived wing morphogenesis GO:0007476 337 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.011
cellular lipid metabolic process GO:0044255 83 0.011
nitrogen compound transport GO:0071705 85 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
response to radiation GO:0009314 155 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
monocarboxylic acid transport GO:0015718 3 0.011
intracellular protein transmembrane transport GO:0065002 4 0.010
regulation of immune response GO:0050776 118 0.010
sterol homeostasis GO:0055092 4 0.010
regulation of notch signaling pathway GO:0008593 100 0.010
cell division GO:0051301 248 0.010
negative regulation of rna metabolic process GO:0051253 251 0.010
small molecule biosynthetic process GO:0044283 37 0.010
cation transport GO:0006812 110 0.010
embryo development ending in birth or egg hatching GO:0009792 152 0.010
respiratory system development GO:0060541 213 0.010
germarium derived egg chamber formation GO:0007293 101 0.010
protein localization to organelle GO:0033365 82 0.010
forebrain development GO:0030900 2 0.010
compound eye development GO:0048749 307 0.010
negative regulation of transcription dna templated GO:0045892 237 0.010

Las disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.053
disease of metabolism DOID:0014667 0 0.027
nervous system disease DOID:863 0 0.024
inherited metabolic disorder DOID:655 0 0.022
disease of cellular proliferation DOID:14566 0 0.016
sensory system disease DOID:0050155 0 0.013
cancer DOID:162 0 0.013
organ system cancer DOID:0050686 0 0.013
central nervous system disease DOID:331 0 0.010
eye and adnexa disease DOID:1492 0 0.010